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Long Bone Fracture


Presentation

  • The authors present evidence that supports a predominantly accidental etiology for isolated spiral tibial fractures of young children.[ncbi.nlm.nih.gov]
  • In this article, we review the presentation, causes, and management of FES presenting with CFE, report a case, and review the literature.[ncbi.nlm.nih.gov]
  • Eleven presented with sudden drop in hemoglobin level, dropping 4.2 g/dL on average. Nine presented with thrombocytopenia, and 10 presented with sudden drop in platelet count, dropping 140,000/dL on average.[ncbi.nlm.nih.gov]
  • The background data of the present participants were almost identical to the subjects participating in the National Health and Nutrition Survey of 2003. Overall, 49.6 % of the subjects had a 25(OH)D value[ncbi.nlm.nih.gov]
  • The present study examines these limitations, based on comparative or large-scale studies from which certain significant results emerge.[ncbi.nlm.nih.gov]
Suggestibility
  • Results are suggestive of a possible interaction between IGF-I and bone repair processes as other investigators have suggested on the basis of animal experiments.[ncbi.nlm.nih.gov]
  • RESULTS: After adjusting for age, gender, race, insurance, and comorbidities, the HR of mortality was 2.89 (95% CI, 2.56-3.28; p CONCLUSIONS: This data suggests that open fracture carries a worse prognosis compared to closed fracture at the same anatomical[ncbi.nlm.nih.gov]
  • Our experiments suggest that the modeling, nail selection, and visualization modules yield adequate results and that fluoroscopic image processing with submillimetric accuracy is practically feasible on clinical images.[ncbi.nlm.nih.gov]
  • The authors suggest that open reduction and internal fixation with cement augmentation is a favorable treatment option for those patients suitable for surgery. However, postoperative radiation therapy may be associated with a low rate of union.[ncbi.nlm.nih.gov]
  • Animal models suggest a key role for dihydroxylated vitamin D metabolites in fracture healing, as evidenced by increases in serum concentration of 24R,25-dihydroxyvitamin D (24R,25[OH]₂D) after long bone fracture.[ncbi.nlm.nih.gov]
Withdrawn
  • Blood samples were withdrawn from the injured patients of all groups at: (a) 24 h, (b) 72 h, (c) 1 week, (d) 2 weeks, and (e) 3 weeks from the time of injury. A 10-ml blood aliquot was withdrawn each time.[karger.com]
Excitement
  • The approaches described, including mode excitation, velocity expressions and energy percentage criteria, may also contribute to ultrasonic monitoring of long bone fracture healing.[ncbi.nlm.nih.gov]
  • The dependence of healing on the interplate distance suggests that maintaining sufficient current across the plates is necessary to allow healing, which for larger bones may be achieved by increasing the area of the plates, the applied voltage, or the excitation[ncbi.nlm.nih.gov]
  • An axial transmission technique has been used to quantify the impact of the gap breakage width and fracture angle on the amplitudes of low order guided wave modes S 0 and A 0 under a 100 kHz narrowband excitation.[ncbi.nlm.nih.gov]
Neglect
  • This article presents a series in which 9 of 10 such spiral fractures were most likely the result of an accident and not child abuse or gross neglect.[ncbi.nlm.nih.gov]
  • KW - Biomechanics KW - Child abuse KW - Fracture morphology UR - UR - U2 - 10.1016/j.chiabu.2003.01.001 DO - 10.1016/j.chiabu.2003.01.001 M3 - Review article VL - 28 SP - 505 EP - 524 JO - Child Abuse and Neglect JF - Child Abuse and Neglect SN - 0145[scholars.northwestern.edu]

Treatment

  • The aim of this study was to determine the rates of long-bone fractures and the proportion of misalignments as indicators of failed treatment or no treatment at all in skeletons from the Giza Necropolis dating to the Old Kingdom period (2700-2190 BC).[ncbi.nlm.nih.gov]
  • Non-surgical treatment may be recommended if little displacement (gap) and/or few bone fragments are present. If your overall health makes you a poor candidate for surgery, non-surgical treatment may also be considered. Initial treatment.[thpg.org]
  • Surgeons will not only be able to monitor the bone healing, but they will also be able to monitor the success of additional treatments such as ultrasound and bone morphologic proteins (BMPs). 2010 Elsevier Ltd. All rights reserved.[ncbi.nlm.nih.gov]
  • Class II fractures (pathologic--osteoporotic) heal well, require minimal specific treatment, and open reduction is usually contraindicated.[ncbi.nlm.nih.gov]
  • Antibiotic cement-coated interlocking nail for the treatment of infected nonunions and segmental bone defects. J Orthop Trauma. 2007;21:258–68. Klemm K. Treatment of infected pseudarthrosis of the femur and tibia with an interlocking nail.[ijoro.org]

Prognosis

  • RESULTS: After adjusting for age, gender, race, insurance, and comorbidities, the HR of mortality was 2.89 (95% CI, 2.56-3.28; p CONCLUSIONS: This data suggests that open fracture carries a worse prognosis compared to closed fracture at the same anatomical[ncbi.nlm.nih.gov]
  • UTSW / Parkland Memorial Hospital) and Stephen Alerhand, MD (@SAlerhand) Overview: When to suspect fat embolism syndrome (FES) Diagnosis of FES and further workup Pathophysiology of the syndrome Management of the critical patient with suspected FES Prognosis[emdocs.net]
  • Prognosis The older you are, the longer it takes to recover from a fracture. Children heal better and more rapidly, so that often after several years there is no visible trace of a fracture on X-rays.[whenithurtstomove.org]

Etiology

  • The authors present evidence that supports a predominantly accidental etiology for isolated spiral tibial fractures of young children.[ncbi.nlm.nih.gov]
  • In our patient, however, the constellation of long bone fractures, sudden hypoxemic respiratory failure, and focal neurologic findings suggested a specific etiology: fat embolism syndrome (FES).[emdocs.net]

Epidemiology

  • CONCLUSION: This 12-year interval retrospective study revealed modern epidemiologic results for FES in long bone fracture.[ncbi.nlm.nih.gov]
  • Borja-Aburto VH, Bustamante-Montes P, Garcia-Sancho MC, Villa-Romero AR (1990) Ionising radiation at low doses and cancer: epidemiological controversy. Rev Invest Clin 42: 312-316.[orthopedics.imedpub.com]
Sex distribution
Age distribution

Pathophysiology

  • The aim of this study was to evaluate possible differences in the serum concentrations of TGF-b1 in cigarette-smoking vs. non-smoking patients with timely and delayed fracture healing in order to understand pathophysiological pathways through which smoking[ncbi.nlm.nih.gov]
  • Emergency Medicine) // Edited by: Alex Koyfman, MD (@EMHighAK, EM Attending Physician, UTSW / Parkland Memorial Hospital) and Stephen Alerhand, MD (@SAlerhand) Overview: When to suspect fat embolism syndrome (FES) Diagnosis of FES and further workup Pathophysiology[emdocs.net]

Prevention

  • Strategies to prevent it and or identify early its development are desirable in order to improve the clinical course of the affected patients and their outcomes.[ncbi.nlm.nih.gov]
  • In other words, NSAIDS may prevent or delay bone healing. These results, however, have not been tested prospectively in humans.[clinicaltrials.gov]
  • Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses. J Bone Joint Surg Am. 1976;58(4):453-8. Eralp L, Kocaoglu M, Rashid H.[ijoro.org]
  • The nails were cut 1.5 cms long and bend to lie along the bony cortex to prevent skin and soft tissue impingement. All fractures had uncomplicated union.[ijoonline.com]
  • Contact an Orthopedic Surgeon in Los Angeles An accurate diagnosis and prompt treatment for a bone fracture are necessary in order to prevent long-term problems and to treat potential underlying causes for weakened bones like osteoarthritis or a tumor[drallison.org]

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