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Loss of Vision

Blind


Presentation

  • CLINICAL PICTURE: We describe 2 patients who presented similarly with acute onset binocular reversible visual loss.[ncbi.nlm.nih.gov]
  • Rhinosinusitis is a common condition which may present with complications commonly involving the orbit and the intracranial space.[ncbi.nlm.nih.gov]
  • Bacterial orbital cellulitis is a condition that rarely presents with complete loss of vision. A case is reported of a 69-year-old man who presented with fulminant onset of proptosis, significant ophthalmoplegia and no perception of light.[ncbi.nlm.nih.gov]
  • Described in the present report is the case of a 26-year-old man who presented with complaints of pain, redness, blurred and loss of vision in the right eye, and swelling of the upper face due to a gunshot injury he had sustained 35 days prior.[ncbi.nlm.nih.gov]
  • Abstract We present a case report of young man with Type 1 diabetes who developed acute visual loss after initially presenting with diabetic ketoacidosis. The diagnosis of invasive paranasal sinusoidal aspergillosis was made following CT and biopsy.[ncbi.nlm.nih.gov]
Pleural Effusion
  • Marked left side pleural effusion and massive pericardial effusion with bilateral hydronephrosis were detected by plain X-ray, echocardiography, and computed tomography, respectively.[ncbi.nlm.nih.gov]
Respiratory Distress
  • Within a few minutes after taking the first dose of the drug, the patient experienced respiratory distress, dizziness, confusion with pain, and loss of color vision, followed by almost complete loss of vision in the right eye.[ncbi.nlm.nih.gov]
Strabismus
  • Strabismus , or squinting, causes victims to have trouble aligning one or both eyes. Homonymous hemianopia is the most common vision impairment. It can be in one or both eyes.[catastrophicallyinjured.com]
  • Suggested resource: www.mdsupport.org/library/stargrdt.html Strabismus Condition in which the eyes are not both directed toward the same point simultaneously. Strabismus occurs when eye muscles are not working together properly.[afb.org]
  • Strabismus Strabismus is an eye condition in which the eyes are not aligned properly and point in different directions. One eye may look straight ahead, while the other may turn inward, outward, downward or upward.[us.optelec.com]
  • Common visual conditions that are found in children with Cerebral Palsy include strabismus, cataracts and refractive issues. Strabismus is a severely turned eye that makes it impossible for both eyes to work together.[cerebralpalsy.org]
  • American Association for Pediatric Ophthalmology and Strabismus www.aapos.org FamilyConnect (For Parents of Children with Visual Impairments) www.familyconnect.org Prevent Blindness America www.preventblindness.org The Association for Retinopathy of Prematurity[mychildwithoutlimits.org]
Tic Disorder
  • Differential diagnosis with tic disorders is discussed, and the patient's treatment approach is described. Although rare, severe clinical complications can occur in OCD.[ncbi.nlm.nih.gov]
Myoclonic Jerking
  • Despite oral inosiplex and supportive care, patient developed generalized seizures with frequent myoclonic jerks and rapidly progressed into coma.[ncbi.nlm.nih.gov]

Workup

  • Further workup requires ophthalmologic consultation and MRI of the head to evaluate for white matter plaque presence. 1-3,29-32 Orbital Infection , particularly orbital cellulitis , leads to visual loss in the later stages of disease.[emdocs.net]
Pericardial Effusion
  • Marked left side pleural effusion and massive pericardial effusion with bilateral hydronephrosis were detected by plain X-ray, echocardiography, and computed tomography, respectively.[ncbi.nlm.nih.gov]
Gliosis
  • In this model, idebenone protected against the loss of retinal ganglion cells, reduction in retinal thickness and gliosis.[ncbi.nlm.nih.gov]
Pleural Effusion
  • Marked left side pleural effusion and massive pericardial effusion with bilateral hydronephrosis were detected by plain X-ray, echocardiography, and computed tomography, respectively.[ncbi.nlm.nih.gov]

Treatment

  • Early and aggressive treatment according to the LCH-II treatment protocol was administered and resulted in remission of the disease.[ncbi.nlm.nih.gov]
  • For the treatment of visual loss, differential diagnosis is important between infection and adverse effect of anti-tuberculous drugs.[ncbi.nlm.nih.gov]
  • Treatment aimed at a gradual return to normal functioning. The patient regained her sight and fully recovered. The final psychiatric diagnosis was psychogenic blindness.[ncbi.nlm.nih.gov]
  • Despite treatment with intravenous flucloxacillin, ceftriaxone and metronidazole, and later, penicillin after Streptococcus pyogenes was grown from tissue culture, there was no improvement in vision; however ocular motility returned to normal.[ncbi.nlm.nih.gov]
  • Delayed and incorrect treatment may result in permanent vision loss, secondary to angle closure glaucoma; therefore it is imperative that prescribing physicians are aware of this rare but serious ocular emergency.[ncbi.nlm.nih.gov]

Prognosis

  • Prognosis and further therapy depends on the systemic stage of disease, which has to be defined by diagnostic work-up.[ncbi.nlm.nih.gov]
  • The clinical presentation, management and prognosis are discussed.[ncbi.nlm.nih.gov]
  • They may have different causes and therefore carry a different prognosis. We studied the influence of differences between characteristics of transient monocular blindness on the diagnosis and management by general practitioners (GPs).[ncbi.nlm.nih.gov]
  • Prognosis is extremely poor. Recovery is unlikely if not treated within 30 minutes.[almostadoctor.co.uk]
  • Prognosis The age of symptom onset (younger patients having a more favorable prognosis) and the causative mutation (patients with MT-ND6 mutations showing highest recovery rates) are factors that determine the disease outcome.[orpha.net]

Etiology

  • Cerebral Hemorrhage/diagnosis Cerebral Hemorrhage/etiology* Female Humans Hypopituitarism/etiology Lymphoma, Large B-Cell, Diffuse/complications* Lymphoma, Large B-Cell, Diffuse/drug therapy Lymphoma, Large B-Cell, Diffuse/pathology Lymphoma, Large B-Cell[ncbi.nlm.nih.gov]
  • Careful patient selection and etiological diagnosis of AHP is required prior to developing a surgical strategy.[ncbi.nlm.nih.gov]
  • Examinations at several medical centers had been unable to establish an etiology.[ncbi.nlm.nih.gov]
  • Erdheim-Chester disease is a rare non-Langerhans-cell histiocytosis of unknown etiology with multi-organ involvement. A 19-year-old woman presented with orthopnea, severe fatigue, bilateral exophthalmos, and gradual loss of vision.[ncbi.nlm.nih.gov]
  • The etiology, clinical presentation, and possible complications are reviewed, as well as the importance of a regular clinical follow-up and early surgical cure.[ncbi.nlm.nih.gov]

Epidemiology

  • He has since completed further training in emergency medicine, clinical toxicology, clinical epidemiology and health professional education.[lifeinthefastlane.com]
  • Summary Epidemiology Prevalence of the disease is not well known but is estimated at 1/15,000 - 1/50,000 people worldwide. Clinical description Sudden, painless, acute or subacute central vision loss is often noted between the ages of 18 to 30.[orpha.net]
Sex distribution
Age distribution

Pathophysiology

  • Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. . Accessed Oct. 30, 2017. Merck Manual Professional Version. . Accessed Oct. 30, 2017.[mayoclinic.org]

Prevention

  • “Studies should also address how poor vision may lead to lower levels of physical and balance activities, as well as on how vision-related fall prevention strategies can be integrated with other fall prevention strategies to more effectively limit falls[futurity.org]
  • Importantly, approximately 90 per cent of blindness or vision impairment is preventable or treatable.[vision2020australia.org.au]
  • Large mucoceles should be removed as quickly as possible to prevent such unacceptable complications as permanent visual loss.[ncbi.nlm.nih.gov]
  • The best way to prevent vision loss from glaucoma is by going to the eye doctor and following your treatment plan as directed. Cataracts Cataracts are a clouding of the eye’s lens.[preventblindness.org]
  • If the person has atrial fibrillation or other reason for clots in the heart, then warfarin (Coumadin) or a related drug is usually used to prevent blood from clotting. If the source is in the neck, treatment might be medicine or surgery.[articles.chicagotribune.com]

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