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Low Protein Diet


Presentation

  • In the present study, we investigated the impact of a low-protein diet on patients' nutritional status in a longitudinal cohort study in peritoneal dialysis patients.[ncbi.nlm.nih.gov]
  • The urine of the present case contained 2-methylcitric acid, 3-hydroxypropionic acid, N-propionylglycine, 2-hydroxy-3-methylbutyric acid, N-tiglylglycine, 3-hydroxyvaleric acid and glutaric acid.[ncbi.nlm.nih.gov]
  • Two siblings, aged 32 and 27 years, with BBS are presented. On admission both patients were obese, with body mass indexes (BMI) of 40 and 39 kg/m2. Their creatinine clearances (CrCl) were 41 and 24 mL/min.[ncbi.nlm.nih.gov]
  • In the present study, we have examined the effect of a low protein, low phosphorus diet on circulating levels of leptin, tumour necrosis factor (TNF)-alpha, and insulin in patients with CRF.[ncbi.nlm.nih.gov]
  • DESIGN: In the present study, the effects of LPD regimen on depressive symptoms in elderly type 2 diabetic subjects with renal failure were investigated.[ncbi.nlm.nih.gov]
Fatigue
  • Without enough of these amino acids, the body starts to experience the subtle signs of low oxygen, which typically manifests itself as low energy levels , fatigue and tiredness.[stack.com]
  • If the person has trouble excreting urine, like many patients with a compromised liver or kidneys, the waste from nitrogen builds up in the bloodstream causing nausea, headaches, fatigue, and further damage to the liver and kidneys.[arizonadigestivehealth.com]
  • Far from increasing energy, that eating style might leave you fatigued and nauseated. Constipation can also be a problem because animal-based protein sources provide little or no fiber.[consumerreports.org]
  • This will cause fatigue and a lack of hunger. If you have chronic kidney failure , eating this way can slow your need for dialysis for up to a year. With kidney failure, you may also need to make other changes.[winchesterhospital.org]
  • If the kidneys, which are responsible for excretion of urea, are not functioning properly (renal failure), or if high levels of protein are continually present in the diet, urea builds up in the bloodstream causing loss of appetite and fatigue.[freedieting.com]
Abdominal Obesity
  • Bardet-Biedl syndrome (BBS) is a rare autosomal-recessive disorder characterized by abdominal obesity, mental retardation, dysmorphic extremities, retinal dystrophy, hypogonadism, and kidney structural abnormalities or functional impairment.[ncbi.nlm.nih.gov]
  • Brinkworth GD, Buckley JD, Noakes M, Clifton PM : Renal function following long-term weight loss in individuals with abdominal obesity on a very-low-carbohydrate diet vs high-carbohydrate diet. J Am Diet Assoc, 2010; 110, 633–638. 29.[nature.com]
Noncompliance
  • RESULTS: Decline rate of GFR, elevation of Cr and BUN and reduction in 1/Cr were significantly lower in compliant patients than in noncompliant patients (p CONCLUSION: LPD therapy is effective in suppressing the progression of CRF when it is well-adhered[ncbi.nlm.nih.gov]
Myopathy
  • KEYWORDS: Bethlem myopathy; Ullrich congenital muscular dystrophy; autophagy; clinical trial; collagen VI; low-protein diet; muscular dystrophies[ncbi.nlm.nih.gov]
Progressive Loss of Vision
  • Abstract Gyrate atrophy of the choroid and retina is an autosomal recessive chorioretinal dystrophy which leads to a slowly progressive loss of vision.[ncbi.nlm.nih.gov]
Eczema
  • In addition to upping your protein intake, these eczema home remedies can help heal your skin too. Sign Up for Our Newsletters Get articles sent right to your inbox Enjoy the BEST stories, advice & jokes! Reader Interactions[rd.com]

Treatment

  • Dietary treatment improved 0.09 QALYs after 2 years, 0.16 after 3 years, 0.36 after 5 years, and up to 0.93 incremental QALYs after the first 10 years.[ncbi.nlm.nih.gov]
  • This study suggests that, in the long-term treatment of gyrate atrophy, the efficacy in slowing the progression of chorioretinal changes and the palatability of a completely natural low-protein diet make this treatment a potentially viable alternative[ncbi.nlm.nih.gov]
  • Data from 57 patients aged or 70 years, with glomerular filtration rate (GFR) 5-7 mL/min, previously participating in a clinical trial demonstrating non-inferior mortality and morbidity of starting sVLPD compared to dialysis treatment, were analysed:[ncbi.nlm.nih.gov]
  • CDDP was also associated with a lower hospitalization rate and reduced need of erythropoietin, as well as of drugs used for treatment of calcium-phosphate abnormalities, thus leading to a significant cost-saving.[ncbi.nlm.nih.gov]
  • Even though, activated charcoal is a cheap treatment for working as adsorbent for nitrogenous products its utility is very limited.[ncbi.nlm.nih.gov]

Prognosis

  • […] essential amino acids and keto-analogues allows a considerable reduction of the protein intake to be achieved which brings about reduction of glomerular hyperfiltration which actually retards the progression of renal failure and improves its short-term prognosis[ncbi.nlm.nih.gov]
  • Conclusion and future research A diet intervention by LPD has modest but significant effects on the course of kidney prognosis in patients with diabetic nephropathy, especially when the intervention is sustainable regarding patients’ compliance.[bmjopen.bmj.com]
  • Holz and Olle Stål, Raptor localization predicts prognosis and tamoxifen response in estrogen receptor-positive breast cancer, Breast Cancer Research and Treatment, 10.1007/s10549-017-4508-x, (2017). Coryn L. Stump, Robert P.[doi.org]

Etiology

  • Kojiro Michitaka, Shuhei Nishiguchi, Yutaka Aoyagi, Yoichi Hiasa, Yoshio Tokumoto and Morikazu Onji, Etiology of liver cirrhosis in Japan: a nationwide survey, Journal of Gastroenterology, 10.1007/s00535-009-0128-5, 45, 1, (86-94), (2009). Harmit S.[doi.org]
  • Scant information has been published on the etiology of TNT in the last 20 years; therefore, recent epidemiological figures, both nationally and internationally, remain unknown.[doi.org]
  • Serum insulin-like growth factor I: tumor marker or etiologic factor? A prospective study of prostate cancer among Finnish men. Cancer Res. 63, 3991–3994 (2003). 85 Pollak, M., Blouin, M. J., Zhang, J. C. & Kopchick, J. J.[doi.org]

Epidemiology

  • , Shanghai, China. 3 Division of Nephrology and Hypertension, Harold Simmons Center for Kidney Disease Research and Epidemiology, University of California Irvine Medical Center, Orange, CA, USA - kkz@uci.edu. 4 Department of Epidemiology, UCLA Fielding[ncbi.nlm.nih.gov]
  • Author information 1 Harold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology & Hypertension, University of California Irvine Medical Center, 101 The City Drive South, Orange, CA, 92868-3217, USA. kkz@uci.edu. 2 Long[ncbi.nlm.nih.gov]
  • Future of Epidemiology Collection In 2018, the Society for Epidemiologic Research and the American Journal of Epidemiology set out to develop a collection of papers on “the future of epidemiology.”[aje.oxfordjournals.org]
  • Stampfer 2 Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School Boston, MA 3 Department of Epidemiology, Harvard School of Public Hearth Boston, MA Search for other works by this author on: Graham A.[doi.org]
  • This study lends epidemiologic support for phenotypic benefits of CR in humans and is consistent with the well‐known literature on animals with regard to CR phenotypes and healthy aging.[doi.org]
Sex distribution
Age distribution

Pathophysiology

  • The latter observations might have particularly important implications for understanding OI pathophysiology and designing more effective therapeutic interventions. Published by Elsevier B.V.[ncbi.nlm.nih.gov]

Prevention

  • In -AA HepG2 cells, C/EBPβ siRNA treatment did not prevent the activation of either ATF3 or ASNS in response to -AA, while ATF4 siRNA prevented the activation of ASNS but not ATF3.[ncbi.nlm.nih.gov]
  • CONCLUSION: A severe low-protein diet is effective not only in preventing deterioration in renal function, but also in maintaining nutritional state despite no supplementation of essential amino acids or keto analogues, even as serum creatinine level[ncbi.nlm.nih.gov]
  • OBJECTIVE: The efficacy of a low-protein diet in the secondary prevention of diabetic nephropathy is not established in patients with type 1 or type 2 diabetes mellitus.[ncbi.nlm.nih.gov]
  • BACKGROUND: While a low-protein diet may preserve residual renal function (RRF) in chronic kidney disease (CKD) patients before the start of dialysis, a high-protein intake is usually recommended in dialysis patients to prevent protein-energy wasting.[ncbi.nlm.nih.gov]
  • […] will help decrease toxins, allowing you to feel better and prevent any symptoms of high toxins in the blood A dietician will explain this special diet to you.[kznhealth.gov.za]

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