Presentation
Presented with midline ulcerated mass. Diagnosis: Squamous cell carcinoma, arising actinic cheilitis 64 year old male with a long history of cigarette smoking presents with an a symetrical nodular mass in the retromolar region. [oralcancerfoundation.org]
Updated, reorganized, and revised throughout, this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation [books.google.com]
Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management. Oral Oncology 45 (2009) 317–323. Medline. [dermnetnz.org]
Numbers show each treatment plan (i.e. ‘1’ for a conventional parallel-opposed plan and ‘2’ for the present RTRT 4-beam plan). Figure 3. Dose–volume histogram (DVH). [academic.oup.com]
Entire Body System
- Dentist
The dentist will then feel your jaw and neck for any lumps or abnormalities. What Happens If My Dentist Finds Something Suspicious? Stay calm. [mouthhealthy.org]
Your doctor or dentist will examine your mouth area. [sharecare.com]
Call your dentist's office immediately if you notice any changes in the appearance of your mouth or any of the signs and symptoms mentioned above. See your dentist on a regular schedule. [webmd.com]
Protect your mouth by seeing a dentist regularly. [colgate.com]
- Swelling
Swelling. Jaw cancer tumors of any significant size will eventually cause a swelling on the face or inside the mouth. Tumors that grow on the inner side of the jawbone can cause a swelling inside the mouth. [dental-health-advice.com]
Symptoms are swelling, pain, tenderness, and unexplained tooth mobility; some tumors are discovered on routine dental x-rays, whereas others are found on routine examinations of the oral cavity and teeth. [merckmanuals.com]
Other symptoms include pain, numbness, and swelling. You may also experience trouble swallowing or moving your tongue or jaw. [sharecare.com]
Any swellings/thickenings, lumps/bumps, rough spots/crusts. Oral cancer doesn't feel like normal gum- it has a scratchy, rougher surface almost sandy in its texture. [jamiethedentist.com]
[…] on the gums, tongue, tonsil, or lining of the mouth A sore throat or persistent feeling that something is caught in the throat Difficulty swallowing or chewing Difficulty moving the jaw or tongue Numbness of the tongue or other area of the mouth Jaw swelling [cancercenter.com]
- Weakness
The most common side effects of any neck dissection are numbness of the ear, weakness when raising the arm above the head, and weakness of the lower lip. [cancer.org]
[…] coughing difficulty breathing weight loss Salivary gland cancer swelling or a lump near the ear, jaw, lip, or inside the mouth different appearance on each side of the face or neck difficulty swallowing or opening mouth widely drooping, numbness or muscle weakness [cancervic.org.au]
Some of these “red flags” include: There is weakness in the muscles of the face on the side of the lump. The lump is attached to the skin on top of it. The skin inside the mouth has a sore or looks different from the skin around it. [headandneckcancerguide.org]
Back in my room I felt sore around the stomach area and generally weak. I was put on a saline drip to keep me hydrated and had to have no food or drink for 12 hours. [mouthcancerfoundation.org]
The after effects often include fatigue, speech problems, trouble maintaining weight, thyroid issues, swallowing difficulties, inability to swallow, memory loss, weakness, dizziness, high frequency hearing loss and sinus damage. [en.wikipedia.org]
- Severe Pain
They can also cause bone tenderness and severe pain. Bony outgrowths (torus palatinus, torus mandibularis) may develop on the palate or mandible. [merckmanuals.com]
Oral cancer can cause severe pain and can cause a bad odor ( halitosis ) in the mouth. Mandibular Tori is different from oral cancer in several ways. Lower Tori symptoms include more symmetrical, smooth growth along the jaw. [mandibulartori.com]
By this time, I had severe pain in my ear. The ENT removed the painful lump, telling us it did not look like cancer, but he was sending it for a biopsy anyway. Four days later we got the call that changed my life forever. [sixstepscreening.org]
Gastrointestinal
- Vomiting
Nausea – some of the many short-term side effects of chemotherapy include nausea, vomiting and hair loss. Palliative care Sometimes, the cancer is too advanced and a cure isn’t possible. [betterhealth.vic.gov.au]
The following adverse effects may occur: fatigue vomiting nausea hair loss weakened immune system, increasing the risk of infection These effects usually go away after finishing treatment. [medicalnewstoday.com]
Side-effects include anorexia, temporary hair loss, nausea, vomiting, and weight loss. Pre-chemotherapy drugs are also given, such as anti-emetics, to reduce side-effects of chemotherapy. [cancerwall.com]
He was concerned that I would vomit up the nose feeder tube when radiotherapy commenced and it would be difficult and painful to replace, because of the soreness and swelling in my mouth and throat. [mouthcancerfoundation.org]
[…] or permanently Weight loss due to a sore mouth, which may make eating difficult Inability to wear dentures for a period of time Depending on the type of treatment, other side effects may include: Fatigue Dental problems lowered immune system Nausea Vomiting [hopkinsmedicine.org]
- Nausea
Nausea – some of the many short-term side effects of chemotherapy include nausea, vomiting and hair loss. Palliative care Sometimes, the cancer is too advanced and a cure isn’t possible. [betterhealth.vic.gov.au]
The following adverse effects may occur: fatigue vomiting nausea hair loss weakened immune system, increasing the risk of infection These effects usually go away after finishing treatment. [medicalnewstoday.com]
Side-effects include anorexia, temporary hair loss, nausea, vomiting, and weight loss. Pre-chemotherapy drugs are also given, such as anti-emetics, to reduce side-effects of chemotherapy. [cancerwall.com]
[…] temporarily or permanently Weight loss due to a sore mouth, which may make eating difficult Inability to wear dentures for a period of time Depending on the type of treatment, other side effects may include: Fatigue Dental problems lowered immune system Nausea [hopkinsmedicine.org]
Jaw & Teeth
- Poor Oral Hygiene
All of these symptoms are from poor oral hygiene, as well as types can not get brush properly when Torus is on the way. Mandibular torus Symptoms Vs. [mandibulartori.com]
Others include poor oral hygiene, irritation caused by ill-fitting dentures, rough surfaces on teeth and poor nutrition. [ucsfhealth.org]
Lydiatt, MD, director of head and neck cancer surgery at the University of Nebraska Medical Center, "Poor oral hygiene over a long period of time, 30 or 40 years, can be a cause oral cancer. This is because of chronic inflammation. [everydayhealth.com]
Risk factors may include: Tobacco use Regular and heavy alcohol consumption Advancing age Sun exposure Poor diet Poor oral hygiene Gum disease Habitual chewing of the lips or cheeks Irritants, such as breathing in smoky, or constantly polluted, atmospheres [betterhealth.vic.gov.au]
- Aphthous Ulceration
Case study: Aphthous ulcers in a 14-year-old girl. Krebs KT. Primary Care Clinic, Child Health Associates, Warrenton, VA, USA. 7. Laryngorhinootologie. 2009 Feb;88(2):112-5. Epub 2008 Dec 8. [capedental.com]
Cancer of the floor of mouth often looks like an ulcer and is painless. Sometimes people mistake this for a canker sore (aphthous ulcer). Often, by the time a patient sees a doctor for a diagnosis, the tumor has grown into the neck. [cedars-sinai.edu]
- Gingival Ulceration
Biopsy Physicians usually collect tissue samples from gingival ulcers and tumors and subject it to histologic examinations. Biopsy is the only test that determines malignancy in the gums. [cancerwall.com]
- Halitosis
Oral cancer can cause severe pain and can cause a bad odor ( halitosis ) in the mouth. Mandibular Tori is different from oral cancer in several ways. Lower Tori symptoms include more symmetrical, smooth growth along the jaw. [mandibulartori.com]
- Oral Ulcers
Secondary syphilis presenting as atypical oral ulceration–a case report. Hayes M, White D, Richards A. Birmingham Dental Hospital, St Chad’s Queensway, Birmingham, UK. 10. J Cancer Res Ther. 2012 Jan;8 Suppl:S111-5. [capedental.com]
Skin
- Ulcer
Diagnosis: Traumatic ulcer The right lateral tongue of this patient demonstrated the presence of an indurated, painless ulcer of unknown duration. [oralcancerfoundation.org]
A non-healing ulcer. A typical ulcer (in dentist speak RAS- = recurrent apthous ulceration), or for you Americans a 'canker sore' looks like this] with a thin red border and a little yellow or pale whiter inside. [jamiethedentist.com]
He told her it was just an ulcer and gave her some antibiotics. [capedental.com]
Ulcers that do not heal within three weeks, any unusual red or white patches, lumps in your neck or jaw area, or persistent hoarseness are all reasons for asking your dental team or doctor to examine you. [dentalhealth.org]
The skin may feel thicker or nodular, or there may be a persistent ulcer or erosion. What is important to note is the persistent nature of these abnormalities. Noncancerous lesions tend to resolve in a few weeks. [healthline.com]
- Freckles
Smokers may have a brown, freckle-like area on the lip instead. The most common sign is an open sore that does not heal. These sores, or ulcers, erode into underlying tissues and bleed intermittently. [livestrong.com]
The radiation from the sun can cause the loss of the skin’s immune function; fine and coarse wrinkles; freckles; mottled pigmentation; sallowness (yellow discoloration of the skin), telangiectasias (the dilation of small blood vessels under the skin), [capedental.com]
Workup
Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. [books.google.com]
Treatment
[…] the treatment approach of the authors. [books.google.com]
What are the treatment options for mouth cancer? Mouth cancer treatments which may be considered include radiotherapy, surgery and chemotherapy. [patient.info]
Treatment often involves surgery performed by a head and neck cancer surgeon. [mskcc.org]
Treatment of mouth cancer What treatment you’re offered will depend on what type of mouth cancer you have, where it is and how far it’s spread. Your doctor will discuss your treatment options with you. [bupa.co.uk]
Prognosis
[…] of origin, the prognosis is usually excellent with appropriate therapy. [dovemed.com]
Although a few cases have been reported in the literature, BSCC appears to be biologically virulent, with a propensity to aggressive local behavior, early regional and distant metastasis, and subsequent poor prognosis. [jstage.jst.go.jp]
[…] this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation, pathology, differential diagnosis, and prognosis [books.google.com]
Survival Rate Jaw Cancer Tonsil Cancer – Pictures, Symptoms, Survival Rate, Staging, Prognosis Duodenal Cancer – Symptoms, Prognosis, Survival Rate and Treatment Medullary Thyroid Cancer – Symptoms, Treatment, Prognosis [cancerwall.com]
In relation to prognosis, it has been widely accepted that CLNM dramatically reduce the long-term survival and prognosis in these patients is described as extremely poor. [ 6, 8, 15, 16 ] Capote-Moreno et al. [ 7 ] reported a decrease in the 5-year survival [parjournal.net]
Etiology
Updated, reorganized, and revised throughout, this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation [books.google.com]
Certain HPV strains are etiologic risk factors for Oropharyngeal Squamous Cell Carcinoma (OSCC) It is important to note that over 25% of all oral cancers occur in people who do not smoke and who only drink alcohol occasionally. [webmd.com]
Oral human papillomavirus (HPV), typically acquired via oral-genital contact, may have a role in the etiology of some oral cancers; however, HPV is identified in oral cancer much less often than it is in oropharyngeal cancer. [msdmanuals.com]
It is a lesion of unknown etiology that actually moves around the mouth over time. [capedental.com]
(Etiology) The cause of development of Adenoid Cystic Carcinoma of Gums is unknown. Some tumors have displayed a fused gene product of chromosome 6 and chromosome 9, called MYB-NFIB gene. [dovemed.com]
Epidemiology
"Epidemiology of oral cancer in Arab countries". Saudi Medical Journal. 37 (3): 249–55. doi : 10.15537/smj.2016.3.11388. PMC 4800887. [en.wikipedia.org]
National Cancer Institute, Surveillance, Epidemiology and End Result Program. Available at https://seer.cancer.gov/statfacts/html/oralcav.html. Accessed: May 20, 2017. Nagler R, Dayan D. The dual role of saliva in oral carcinogenesis. [emedicine.medscape.com]
Incidence, Epidemiology and Pathology Although cancers of the head and neck region only account for five percent of all cancers reported yearly in the human body, 30 percent of these cancers occur in the oral cavity. [ahns.info]
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA. 5. Fogorv Sz. 2009 Jun;102(3):103-9. [The oral lichen planus: doubts and evidence]. [capedental.com]
Pathophysiology
Pathophysiology In oral squamous cell carcinoma (OSCC), modern DNA technology, especially allelic imbalance (loss of heterozygosity) studies, have identified chromosomal changes suggestive of the involvement of tumor suppressor genes (TSGs), particularly [emedicine.medscape.com]
Pathophysiology [ edit ] Oral squamous cell carcinoma is the end product of an unregulated proliferation of mucous basal cells. [en.wikipedia.org]
Prevention
These startling statistics from the Centers from Disease Control and Prevention tell a warning tale, but there is some good news, too. If caught early, oral cancer is highly treatable. [consumer.healthday.com]
[…] say whether the HPV vaccine will prevent these cancers. [mouthhealthy.org]
Fluoride is used to help prevent the formation of cavities. [dana-farber.org]
Preventing mouth cancer The three most effective ways of preventing mouth cancer developing, or preventing it coming back after successful treatment, are: not smoking ensuring you don't drink more than the recommended weekly limits for alcohol eating [nhs.uk]
These cancers are very treatable if caught early, and are easily preventable. The most common causes of head and neck cancer are tobacco and alcohol use. [my.clevelandclinic.org]