Moreover, as our patient's dysphagia improved with physiotherapy and swallowing/speech exercises, there is a possibility that it might have been because of the relative hypotonia of the pharyngeal muscles. [journals.sagepub.com]

Although our patient presented with acute-onset dysphagia, the reasons cannot be clearly stated. [journals.sagepub.com]

[…] severe micrognathia and a missense variant in MED12. 61 Prescott TE...Stray-Pedersen A 27286923 2016 20 Lujan-Fryns Syndrome (LFS): A Unique Combination of Hypernasality, Marfanoid Body Habitus, and Neuropsychiatric Issues, Presenting as Acute-Onset Dysphagia [malacards.org]

Although our patient presented with acute-onset dysphagia, the reasons cannot be clearly stated. [journals.sagepub.com]

[…] severe micrognathia and a missense variant in MED12. 61 Prescott TE...Stray-Pedersen A 27286923 2016 20 Lujan-Fryns Syndrome (LFS): A Unique Combination of Hypernasality, Marfanoid Body Habitus, and Neuropsychiatric Issues, Presenting as Acute-Onset Dysphagia [malacards.org]

Lujan (Lujan-Fryns) syndrome is characterised by tall stature with asthenic habitus, macrocephaly, a tall narrow face, maxillary hypoplasia, a high narrow palate with dental crowding, a small or receding chin, long hands with hyperextensible digits, hypernasal [portal.sahmriresearch.org]

LFS is characterised by tall stature with asthenic habitus, macrocephaly, a tall narrow face, maxillary hypoplasia, a high narrow palate, a small or receding chin, long hands with hyperextensible digits, hypernasal speech, hypotonia, mild-to-moderate [genome.jp]

Clinically, the patients can be recognized by the facial morphology in addition to the presentation of some of the following features: tall marfanoid stature, macrocephaly, long hands with hyperextensible digits, mild general hypotonia and mild to moderate [scielo.mec.pt]

Lujan (Lujan–Fryns) syndrome is characterised by tall stature with asthenic habitus, macrocephaly, a tall narrow face, maxillary hypoplasia, a high narrow palate with dental crowding, a small or receding chin, long hands with hyperextensible digits, hypernasal [digital.library.adelaide.edu.au]

On examination, the patient presented high stature, prominent forehead, large nose, deep and short filters, long narrow face, low-set ears, small mandible, long arms and fingers, and hypotonia (Figure). He also showed severe mental retardation. [scielo.br]

He denied any cough, headache, facial pain, or breathing problems. He did not have any paresthesias or weakness in any of his limbs. He had normal cranial nerve functions, including normal vision, hearing, and taste. [journals.sagepub.com]

They frequently present mental retardation with developmental delay and a distinctive behaviour, with hyperactive personality and excessive talkativeness. FGS is characterized by clinical variability and genetic heterogeneity. [scielo.mec.pt]

He did not have any paresthesias or weakness in any of his limbs. He had normal cranial nerve functions, including normal vision, hearing, and taste. He did not use any regular medications. [journals.sagepub.com]