Presentation
Subgroup analysis and investigation of heterogeneity If data had sufficed, we would have undertaken subgroup analyses to test the effect of interventions in participants presenting with asymmetrical weakness versus symmetrical weakness and of patients [cochranelibrary.com]
Entire Body System
- Disability
Types of outcome measures Primary outcomes Our primary outcome was change in disability from baseline as measured by an appropriate, validated scale such as the lower limb scale of the Overall Disability Sum Score (ODSS) (Merkies 2002), at 12 months. [cochranelibrary.com]
- Unconsciousness
Sensory symptoms include paresthesias (tingling), hypesthesia (reduced sensation), allodynia (pain on touch) and autonomic dysfunction (damage to nerves that control unconscious functions). [cochranelibrary.com]
Treatment
Types of interventions Treatment with IVIg, corticosteroids, PE or any other form of immunotherapy for ILSP compared with no treatment, placebo, or other treatment. [cochranelibrary.com]
Prognosis
Since ILSP is similar to diabetic amyotrophy with respect to its pathophysiology, clinical features, and prognosis (Dyck 2001b; Dyck 2002), it may be relevant to note that an RCT found pulse methylprednisolone therapy not superior to placebo for functional [cochranelibrary.com]
Etiology
The etiology and pathogenesis of ILSP is uncertain, but the disorder is considered to be immune‐mediated in origin. [cochranelibrary.com]
Pathophysiology
Since ILSP is similar to diabetic amyotrophy with respect to its pathophysiology, clinical features, and prognosis (Dyck 2001b; Dyck 2002), it may be relevant to note that an RCT found pulse methylprednisolone therapy not superior to placebo for functional [cochranelibrary.com]
Prevention
The current standard treatment is insufficient to either relieve the pain or to prevent (ongoing) nerve damage. [cochranelibrary.com]