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Lung Scarring


Presentation

  • They found that cough was present in 84% of patients. It was more common in patients with advanced disease and in those who had never smoked.[wiley.com]
  • Presents more than 120 high-quality images which complement the discussion of specific diseases and provide a clear framework for understanding difficult pulmonary concepts.[books.google.de]
  • For lungs to return to a healthy structure after injury, fibroblasts — cells in collective tissue that produces collagen and other wound-healing fibers — must be present, but not at excessive levels.[rtmagazine.com]
  • Christopher Ryerson, MD, of the University of California, San Francisco and his colleagues studied 242 patients with idiopathic pulmonary fibrosis and found that cough was present in 84 percent of patients.[medicaldaily.com]
Pulmonary Disorder
  • Guides you through the anatomy, physiology, and pathophysiology relevant to major pulmonary disorders, and then focuses on the clinical aspects and treatment of specific diseases.[books.google.de]
  • Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal pulmonary disorder.[clinicaltrials.gov]
  • The first modern evidence of fibrotic pulmonary disorder in an asbestos worker was discovered in an autopsy performed by Dr Montague-Murray in England in 1899, and reported on in 1907.[asbestosassociation.com.au]
Dermatitis
  • Minocycline is also used to treat several other diseases such as nocardiasis, mycobacteriosis, leprosy, lyme disease, pyoderma gangrenosum, autoimmune bullous dermatitis, carteaud disease, and prurigo.[clinicaltrials.gov]
Vaginal Dryness
  • As women reach menopause and beyond, more than 80% will experience symptoms such as hot flashes, night sweats, sleep disturbance, and vaginal dryness. [1] Estrogen, with or without progestin, is the most effective treatment for many of these symptoms.[news.cancerconnect.com]

Workup

  • Diagnosis and treatment of lung cancer is a complex topic and a pulmonary specialist should be involved in the workup of a suspected lung cancer.[medicinenet.com]
X-Ray Abnormal
  • X-ray abnormalities include thickening of the lining of the lungs and tiny lines marking the lower portions of the lungs. However, up to 20% of patients have completely normal-appearing chest X-rays.[medicinenet.com]
  • Stages of sarcoidosis describe the chest x-ray abnormality: Stage I disease has only enlarged hilar and mediastinal lymph nodes (these gland sit outside the lungs); Stage II disease has enlarged lymph glands as seen in Stage I disease, but it also has[sarcoid-network.org]
Chest X-Ray Abnormal
  • Stages of sarcoidosis describe the chest x-ray abnormality: Stage I disease has only enlarged hilar and mediastinal lymph nodes (these gland sit outside the lungs); Stage II disease has enlarged lymph glands as seen in Stage I disease, but it also has[sarcoid-network.org]
Pericardial Effusion
  • No pleural or pericardial effusions. Central airways patent. I've had a chronic barking cough and am an occasional smoker and ex full time smoker (never again!).[healthunlocked.com]

Treatment

  • Treatment The lung scarring that occurs in interstitial lung disease is irreversible and treatment will not always be effective. Treatments may improve symptoms temporarily or slow the disease’s progress.[sleepandlungcare.com.au]
  • […] severity and complications of disease and potential side effects of treatment.[chicagohealthonline.com]
  • This specialist is most familiar with diagnosis and treatment of this disorder and will be your best resource for the newest updates in treatment.[spokesman.com]
  • Follow your doctor’s advice for both treatment course and follow up. Sticking to your disease management plan if the scarring results from radiation for lung cancer treatment or another chronic condition. This may include immunotherapy.[healthline.com]
  • The goals of treatment are to hopefully slow the progression of the disease, reduce symptom flare-ups and help the person with pulmonary fibrosis to live an active and healthy life.[lunginstitute.com]

Prognosis

  • Lung scarring, or pulmonary fibrosis is a devastating disease with poor prognosis. We are particularly interested in Idiopathic Pulmonary Fibrosis, which is a scarring disease of unknown origin.[urmc.rochester.edu]
  • Ryerson and his colleagues concluded that patients with idiopathic pulmonary fibrosis that cough may have a worse prognosis compared with patients who do not cough.[medicaldaily.com]
  • However, for any individual, prognosis is difficult to determine with high accuracy. (Robert H.[chicagohealthonline.com]
  • The authors concluded that patients with idiopathic pulmonary fibrosis who cough may have a worse prognosis compared with patients who do not cough.[wiley.com]

Etiology

  • Since the 1930s, scars have been postulated to play an etiologic role in lung cancer, 12 based on the observation that lung cancers frequently arise in proximity to scar tissue.[ncbi.nlm.nih.gov]
  • (Etiology) The following are some of the known or suspected causes of Radiation-Induced Pulmonary Fibrosis: Radiation therapy for certain cancers administered to the chest region; the cancers may include breast, lung, and neck cancers Radiation exposure[dovemed.com]
  • Blood tests: These tests are used to evaluate blood markers that may suggest an underlying autoimmune etiology for pulmonary fibrosis, including, for example, rheumatoid arthritis, lupus and scleroderma Treatment of Pulmonary Fibrosis There is no current[foundation.chestnet.org]

Epidemiology

  • A study published in the American Journal of Epidemiology provides additional evidence that postmenopausal hormone therapy consisting of estrogen alone increases the risk of endometrial (uterine) cancer in women who have not had a hysterectomy.[news.cancerconnect.com]
  • Seite 69 - Epidemiology is defined as the study of the distribution and determinants of health-related states or events in specified populations, and the application of this study to control of health problems. ‎[books.google.de]
  • Inflammation in the development of lung cancer: epidemiological evidence. Expert Rev Anticancer Ther. 2008; 8 (4):605–615. [ PubMed ] [ Google Scholar ] 9. Ballaz S, Mulshine JL.[ncbi.nlm.nih.gov]
  • Schluger, Prof of Medicine, Epidemiology and Environmental Health Science Columbia University, is an annual visitor to MSIH where he participates in the 2nd year Respiratory Clerkship, training MSIH students as they study the thorax “system” in anatomy[msih.bgu.ac.il]
  • The Epidemiology of Interstitial Lung Diseases. Am J Respir Crit Care Med. Oct 1994;150(4):967-72. cited by Michaelson JE, Aguayo SM, Roman J. Idiopathic Pulmonary Fibrosis: A Practical Approach for Diagnosis and Management. Chest.[en.wikipedia.org]
Sex distribution
Age distribution

Pathophysiology

  • Guides you through the anatomy, physiology, and pathophysiology relevant to major pulmonary disorders, and then focuses on the clinical aspects and treatment of specific diseases.[books.google.de]

Prevention

  • […] cardiology at the Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease.[hopkinsmedicine.org]
  • All three studies compared the effects of both oxygen and air in all participants while they did an exercise test, while preventing them from knowing which treatment they were being given.[cochrane.org]
  • Treatment is aimed at preventing more scarring, improving symptoms and maintaining the ability to get around and stay healthy. Medications to reduce inflammation, such as prednisone, are commonly administered.[spokesman.com]
  • For the first time ever, molecular therapy for the repair of damage to the lungs caused by genes and cells and thus for the prevention of fibrosis or tumors, which also occur as a result of DNA damage, may be within reach," said first author Dr.[phys.org]

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