He presented with dyspnea grade III according to the Medical Research Council. [ncbi.nlm.nih.gov]

• Pain

  OBJECTIVE: Our objective was to examine variability in pain levels following lung transplantation, and examine individual biopsychosocial factors influencing changes in pain. [ncbi.nlm.nih.gov]

• Sepsis

  Two weeks postoperatively, he suffered from central vein catheter-related sepsis due to methicillin-sensitive Staphylococcus aureus. After being successfully treated for sepsis, he was discharged. [ncbi.nlm.nih.gov]

  Founded in 1905 to combat TB, the ATS has grown to tackle asthma, COPD, lung cancer, sepsis, acute respiratory distress, and sleep apnea, among other diseases. [thoracic.org]

  The first patient died 2 months after transplantation from sepsis, while the second patient was living at the time of their publication [7]. [academic.oup.com]

• Fever

  Manifestations of Lung Transplant Rejection by Category Rejection Category Manifestations Hyperacute Poor oxygenation, fever, cough, dyspnea, decreased FEV 1 Accelerated Poor oxygenation, fever, cough, dyspnea, infiltrate seen on chest x-ray, decreased [merckmanuals.com]

  Symptoms include fever, cough and dyspnea. Physical exam may reveal fever and changes in the pulmonary exam, such as crackles or rhonchi. [aspergillus.org.uk]

  Signs of heart rejection include fatigue, swelling of the arms or legs, weight gain, and fever. [emedicinehealth.com]

  Call your transplant team if you have signs of rejection, such as: Fever of 100.4°F (38°C) or higher, or as advised by your medical team Flu-like symptoms such as body aches Fluid in the lung Tiredness Feeling short of breath Cough New chest pain [hopkinsmedicine.org]

• Falling

  United States of America. 2 Office of the Clinical Director, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America. 3 Advanced Lung Disease and Transplant Program, Inova Fairfax Hospital, Falls [ncbi.nlm.nih.gov]

  He had been waiting for a transplant since last fall, according to Dr. William A. Baumgartner, who directs the heart-lung transplant program at Johns Hopkins. [query.nytimes.com]

  To diagnose BOS there must be a fall in FEV 1 of 10–19% or a greater than 25% decrease in FEF 25–75 and the drop must be sustained on two occasions more than 3 weeks apart [ 22 ]. [breathe.ersjournals.com]

  ISHLT criteria for timing of referral in patients with cystic fibrosis are as follows [8] : FEV 1 that has fallen to 30% or a patient with advanced disease with a rapidly falling FEV 1 A 6-minute walk distance Development of pulmonary hypertension in [emedicine.com]

• Weight Loss

  Symptoms of AAT deficiency include: Shortness of breath and wheezing Repeated lung infections Tiredness Rapid heartbeat upon standing Vision problems Weight loss Some people have no symptoms and do not develop complications. [wexnermedical.osu.edu]

  Those who can walk are enrolled in exercise and weight-loss programs to improve their overall condition. [emedicinehealth.com]

  Symptoms may be non-specific, including fever, weight loss, breathlessness and lethargy. The most common radiological findings are solitary or multiple pulmonary nodules. [breathe.ersjournals.com]

  Other indicators of poor prognosis are weight loss, recurrent pneumothoraces, frequent hospitalization, and hemoptysis. Liou and colleagues have validated a 5-year survivorship model for cystic fibrosis. [emedicine.com]

• Cough

  Although the patient maintained complete remission, dry cough and back pain appeared 8 years after the chemotherapy. [ncbi.nlm.nih.gov]

  Manifestations of Lung Transplant Rejection by Category Rejection Category Manifestations Hyperacute Poor oxygenation, fever, cough, dyspnea, decreased FEV 1 Accelerated Poor oxygenation, fever, cough, dyspnea, infiltrate seen on chest x-ray, decreased [merckmanuals.com]

  The most common symptoms of chronic bronchitis include a cough, often called smoker’s cough, coughing up mucus, wheezing and chest discomfort. [uwmedicine.org]

  You may have coughing or wheezing. The shortness of breath becomes so severe that it limits your exercise and daily activities. [emedicinehealth.com]

• Dyspnea

  The purpose of this prospective study was to examine the effects of Nordic walking on lung function, perception of dyspnea, and health-related quality of life in patients referred for lung transplantation. [ncbi.nlm.nih.gov]

  Manifestations of Lung Transplant Rejection by Category Rejection Category Manifestations Hyperacute Poor oxygenation, fever, cough, dyspnea, decreased FEV 1 Accelerated Poor oxygenation, fever, cough, dyspnea, infiltrate seen on chest x-ray, decreased [merckmanuals.com]

• Respiratory Distress

  Extended (intra-pericardial) left pneumonectomy was successfully performed, but the patient died a few weeks later due to acute respiratory distress syndrome. [ncbi.nlm.nih.gov]

  Founded in 1905 to combat TB, the ATS has grown to tackle asthma, COPD, lung cancer, sepsis, acute respiratory distress, and sleep apnea, among other diseases. [thoracic.org]

  Repeated chest roentgenograms revealed changes consistent with adult respiratory distress syndrome (ARDS). Tracheostomy was required on hospital day 23. [academic.oup.com]

  Infants with this condition usually die within days or weeks of birth due to severe respiratory distress. [stlouischildrens.org]

• Respiratory Insufficiency

  Lung or heart-lung transplantation is an option for patients who have respiratory insufficiency or failure and who remain at risk of death despite optimal medical treatment. [msdmanuals.com]

  insufficiency or failure and who remain at risk of death despite optimal medical treatment. [merckmanuals.com]

• Overeating

  Her chest wall was extremely flattened over time, and her respiratory condition progressively deteriorated. She underwent semielective bilateral living-donor lobar lung transplantation. [ncbi.nlm.nih.gov]

  Over the ensuing decade, the number of lung transplants performed worldwide increased rapidly. In 1987, approximately 45 transplants were performed, and by 1990, over 400 were performed worldwide. [secondwindstl.org]

• Nausea

  Signs of rejection: fever; flu-like symptoms, including chills, dizziness, nausea, general feeling of illness, night sweats; increased difficulty in breathing; worsening pulmonary test results; increased chest pain or tenderness; increase or decrease [en.wikipedia.org]

  Other symptoms include the following: Nausea and vomiting Weight gain Confusion Swelling of your arms and legs ( edema ) Severe fatigue and tiredness Decreased urine The main symptom for lung disease is shortness of breath. [emedicinehealth.com]

• Vomiting

  Other symptoms include the following: Nausea and vomiting Weight gain Confusion Swelling of your arms and legs ( edema ) Severe fatigue and tiredness Decreased urine The main symptom for lung disease is shortness of breath. [emedicinehealth.com]

  […] transplantation include: Squamous cell skin carcinoma within the last 2 years Body mass index of 38 Single vessel coronary artery disease Aspergillus colonisation of the lungs Current smoker Symptoms or signs of acute rejection may include: Breathlessness Hypoxia Vomiting [breathe.ersjournals.com]

• Hypertension

  Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension caused by alteration of pulmonary veins. [ncbi.nlm.nih.gov]

  […] hospitalization Rapid lung function decline World Health Organization functional class IV Pulmonary arterial hypertension The median survival for patients with primary pulmonary hypertension is 2.8 years. [emedicine.com]

• Heart Disease

  […] congenital heart disease The Freeman Hospital is the primary transplant centre in the UK to offer heart transplants for adults with complex congenital heart disease. [newcastle-hospitals.org.uk]

  We also have expertise in managing complex illnesses, coronary artery disease, valvular heart disease and multi-drug resistant infections. Our transplant teams are experienced in multi-organ transplants as well. [health.ucsd.edu]

  In addition, the risk of bone and heart disease is increased. Lung Transplantation Referral for evaluation for lung transplantation should be considered when the FEV1 approaches 30%. [thelamfoundation.org]

  Our surgeons perform life-saving heart and lung transplants on children who have: Congenital heart disease Cardiomyopathy Cystic fibrosis Pulmonary hypertension Types of Heart and Lung Transplants We Offer Our transplant surgeons at the Heart Institute [chp.edu]

  Other conditions include: pulmonary fibrosis/ interstitial lung disease pulmonary hypertension pulmonary vascular congenital heart diseases graft versus host disease of the lung after bone marrow transplantation chronic lung disease of infancy (CLD) Evaluation [childrenshospital.org]

• Mood Swings

  Progestins can cause fluid retention and mood swings. They are no longer routinely used in patients with LAM. Gonadotrophin-releasing hormone ( GnRH ) antagonists (receptor blockers ), such as LUPRON® (leuprolide), induce menopause. [thelamfoundation.org]

  Corticosteroids have many different side effects, including easy bruising of the skin, osteoporosis, damage or death of portions of bone, high blood pressure, high blood sugar or diabetes, stomach ulcers, weight gain, acne, mood swings, and a "moon" face [emedicinehealth.com]

• Dizziness

  Signs of rejection: fever; flu-like symptoms, including chills, dizziness, nausea, general feeling of illness, night sweats; increased difficulty in breathing; worsening pulmonary test results; increased chest pain or tenderness; increase or decrease [en.wikipedia.org]

Both patients performed the 6MWT for a lung transplantation workup while dependent on MV. [ncbi.nlm.nih.gov]

Candidates over the age of 70 years are not routinely referred for workup for lung transplantation. Arbitrary restrictions exist for most programs. The conventional definition offered for “elderly” patients is older than 65 years of age (Fig. 2 ). [link.springer.com]

Antiviral treatment with CDV was individually adapted according to anti-ADV immune responses, which provides a new method for tailoring antiviral treatment in lung transplant recipients. [ncbi.nlm.nih.gov]

CONCLUSION: Elevated mPAP, dPAP, and sPAP are related to worse prognosis in patients with esLD referred for lung transplantation. Copyright © 2018 Elsevier Inc. All rights reserved. [ncbi.nlm.nih.gov]

This case report describes infection by S. prolificans, which rarely becomes an etiologic agent in lung transplant patients, and shows that endobronchial topical amphotericin B instillation is a therapeutic option when systemic antifungal treatment is [ncbi.nlm.nih.gov]

This article reviews the epidemiology, pathogenesis, risk factors, prevention, and treatment of primary graft dysfunction. Copyright © 2017 Elsevier Inc. All rights reserved. [ncbi.nlm.nih.gov]

Epidemiology of aspergillosis in lung transplant recipients is fairly well-defined; the challenge remains both diagnosis and treatment of this disease. [aspergillus.org.uk]

[…] thromboembolic pulmonary hypertension ( CTEPH ) First lung-kidney transplant in Ohio (only 37 performed in the U.S. since 1995) Lung transplant research: Multidisciplinary research collaboration with Nationwide Children’s Hospital at the Center for the Epidemiological [wexnermedical.osu.edu]

Primary pulmonary hypertension: pathophysiology and therapy Stuart Rich 2. Genetics of pulmonary hypertension Richard C. Trembath and Rachel Harrison 3. Pathology of pulmonary hypertension Anne E. Bishop and Julia M. Polak 4. [cambridge.org]

Am J Respir Crit Care Med 172:379–383 CrossRef PubMed Google Scholar Verleden GM, Egan J, Israel-Biet D et al (2004) Chronic lung allograft rejection: prevalence, pathology, risk factors and pathophysiology. [link.springer.com]

[…] hypertension, CF, and COPD, each with a 6-month survival of 96%.. 64 This high early mortality seen after lung transplantation in patients with pulmonary hypertension likely reflects the ability of vasodilator therapy to prolong life despite significant pathophysiology [phaonlineuniv.org]

Long-term toxicities attributed to tacrolimus, such as nephrotoxicity and neurotoxicity, can limit the long-term success of tacrolimus in preventing allograft rejection. [ncbi.nlm.nih.gov]