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Luteinizing Hormone Deficiency
Lh Luteinising Hormone Defic

Presentation

Stress-related hypogonadotropic hypogonadism presents in women as amenorrhea. [emedicine.medscape.com]

Females present with primary amenorrhea, and some males present with micropenis. Kallmann syndrome results from the congenital absence of GnRH-producing neurons in the hypothalamus. [thehealthscience.com]

Abstract: A case report of an 18-year-old male with luteinizing hormone (LH) deficiency in hereditary congenital adrenal hypoplasia, probably of the cytomegalic type, is presented. [popline.org]

Presenting underlying mechanisms and pathologies, as well as diagnostic methods, Growth Hormone Deficiency will provide the most up-to-date essential information and evidence on this condition for the clinical endocrinologist. [books.google.com]

Our case highlights the various endocrinological presentations that can present concomitantly with this rare syndrome. Case report A 32 year old woman came to our clinic for the evaluation of amenorrhea and hyperprolactinemia. [f1000research.com]

Entire Body System

  • Male Hypogonadism

    Irvin Hirsch, Male Hypogonadism, Merck Manuals Dec 2014 [dontcookyourballs.com]

    Male Hypogonadism. ARUP Consult. Available online at https://arupconsult.com/content/hypogonadism-male?_ga=2.126530189.1479446145.1525530915-171446445.1522145782. Accessed on 5/05/19. Vogiatzi, M. (2018 February 11, Updated). Hypogonadism. [labtestsonline.it]

    Male hypogonadism due to a mutation in the gene for the beta-subunit of follicle-stimulating hormone. N Engl J Med. 1998 Jun 11. 338(24):1729-32. [Medline]. Kalantaridou SN, Makrigiannakis A, Zoumakis E, Chrousos GP. [emedicine.medscape.com]

  • Tall Stature

    Signs and symptoms of excess GH In children (gigantism): Abnormally rapid growth Very tall stature Painful joints Excessive sweating. [innerbody.com]

Workup

Consider MRI if workup suggests hypothalamic or pituitary mass or other abnormality (eg, abnormal pituitary hormone levels, visual field lesions, or neurologic signs). Testicular ultrasound if testicular masses are detected on examination. [hiv.va.gov]

In both women and men, LH is often used in conjunction with other tests ( FSH, testosterone, estradiol and progesterone ): In the workup of infertility To aid in the diagnosis of pituitary disorders that can affect LH production To help diagnose conditions [labtestsonline.org]

Treatment

Measures of treatment effect We used the following measures of the effect of treatment. [cochranelibrary.com]

Luteinizing Hormone Deficiency Treatment Treatment options can be directed at the hypogonadism on its own or the pituitary dysfunction. [healthhype.com]

Treatment Medical Care Hypogonadotropic hypogonadism Treatment of hypogonadotropic hypogonadism depends on the gender and age of the patient as well as their desire for current fertility. [emedicine.medscape.com]

More studies are needed in infertile male patients with LH variants to demonstrate if recombinant LH or hCG treatment could be beneficial in selected populations. [austinpublishinggroup.com]

Apart from the demographic data, anamnestic details e.g. reason for the infertility, duration of the unfulfilled wish for children, past medical treatment for conception and accompanying illnesses will be documented. [clinicaltrials.gov]

Prognosis

Improving the criteria for POR, with a stratification that incorporates prognosis for pregnancy, may help to improve ART success rates for women with this condition. [excemed.org]

Outlook (Prognosis) Acute pituitary infarction is a potentially life-threatening event. Prognosis for chronic deficiency (which is detected and treated) is good. [medicine.georgetown.edu]

What Is the Prognosis for Hypopituitarism? With appropriate treatment, the prognosis is very good. [emedicinehealth.com]

What is the prognosis for a person with PROP1-related Combined Pituitary Hormone Deficiency? People with PROP1-related CPHD are typically able to live a normal lifespan. [counsyl.com]

Outlook If hormone replacement therapy is adequate, the prognosis is good. Complications are often related to the underlying disease. For More Information Visit the Pituitary Network Association web site. [webmd.com]

Etiology

The final section describes the different etiologies of GH deficiency, from molecular mechanisms and gene abnormalities to cranial radiation and traumatic brain injury, along with syndromes related to this deficiency. [books.google.com]

They are organised into groups, and further divided into clinical, etiological or histopathological sub-types. [orpha.net]

When considering pathology related to the pituitary itself, the most common etiology of either over- or under-production of pituitary hormones in adults is a pituitary lesion. [clinicaladvisor.com]

Although these 421 patients were only screened for KAL1, this result implies that KAL1 mutations only contribute to CPHD/SOD etiology to a minor extent, if any. [nature.com]

Further, the extent of excessive visceral fat is negatively correlated with GH production, whereas exercise appears to be positively correlated. 2 There are many different etiologies for GHD in adults. [ajmc.com]

Epidemiology

Epidemiology Hypopituitarism is a rare disorder that affects less than 200,000 individuals in the United States, with an incidence of 4.2 cases per 100,000 people per year. [news-medical.net]

Genatlas disease for FSHB Gene delayed puberty,primary amenorrhea,infertility (FSH deficiency,isolated),hypogonadism in man Relevant External Links for FSHB Genetic Association Database (GAD) FSHB Human Genome Epidemiology (HuGE) Navigator FSHB Atlas [genecards.org]

Whether this condition results from inadequate LH secretion to stimulate progesterone production by the corpus luteum or an inadequate response of the corpus luteum to appropriate LH stimulation is unclear. [7, 8, 12] Epidemiology Frequency United States [thehealthscience.com]

It has been shown that the degree of elevation in lipid level 3 and the severity of bone mineral loss correlate with the severity of GHD. 4 Epidemiologic studies have clearly shown that adults with hypopituitarism, including GHD, display an increased [ajmc.com]

Epidemiology Frequency United States Hypogonadotropic hypogonadism has an overall incidence of approximately 1:10,000 to 1:86,000 men and women. Two thirds of the time, this is associated with anosmia (ie, Kallmann syndrome). [emedicine.medscape.com]

Pathophysiology

[…] disease/hypopituitarism/overview.html http://www.mayoclinic.org/diseases-conditions/hypopituitarism/home/ovc-20201485 Further Reading Hypopituitarism Diagnosis Hypopituitarism Treatment Hypopituitarism Causes Hypopituitarism Epidemiology Hypopituitarism Pathophysiology [news-medical.net]

Clinically, only FSH is used as a marker of testicular dysfunction. [4] Pathophysiology Hypothalamic causes of LH deficiency Kallmann syndrome Kallmann syndrome was first described by Franz Hosef Kallmann in 1944 and refers to congenital secondary hypogonadism [thehealthscience.com]

Pathophysiology [ edit ] The pituitary gland is located at the base of the brain, and intimately connected with the hypothalamus. [en.wikipedia.org]

Prevention

Seite 142 - Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. ‎ [books.google.de]

Plate sealers not used or reused Cover assay plate with plate sealer, use a fresh sealer each time to prevent contamination [biovision.com]

Prevention Pituitary adenomas are not associated with any known lifestyle or environmental risk factors, so there are no available methods to prevent the condition. [innerbody.com]

Getting pregnant requires that the delicate balance of hormones is intact; any disturbance in the hormone balance can result in menstrual difficulties that prevent pregnancy. [livestrong.com]

If estradiol is started within 10 years of menopause, it can prevent spine and hip bone fractures. Estradiol also promotes puberty. Ovulation induction agents (like follitropin alfa, clomiphene citrate) promote ovulation. [healthhype.com]

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