A case of giant lymph node hyperplasia presenting as a lump in the neck is reported together with a review of the literature relating to the presentation of this unusual disorder in the head and neck. [ncbi.nlm.nih.gov]

• Fever of Unknown Origin

  One patient's disease had a subacute course with fevers of unknown origin, mucocutaneous candidiasis, and progressive thrombocytopenia, while the other patient's disease had a fulminant course with anemia, thrombocytopenia, and splenic lymphoma. [ncbi.nlm.nih.gov]

• Soft Tissue Mass

  Conventional radiographs show a well-defined soft tissue mass. [jpgmonline.com]

• Mediastinal Disease

  IgG4-related sclerosing disease Treatment should be considered for lung, pleural, or mediastinal disease that is associated with symptoms, physiologic impairment, or progression over time. [pulmonologyadvisor.com]

• Xanthoma

  Abstract A patient is described who had generalized plane xanthomas, cutaneous vasculitis, peliosis hepatis, and intraabdominal giant lymph node hyperplasia of the plasma cell type. [ncbi.nlm.nih.gov]

• Xanthelasma

  Abstract We present a new case of hepatic sinusoidal dilatation associated to giant lymph node hyperplasia or Castleman's disease in a 23-year-old patient with xanthelasmas and history of celiac disease. [ncbi.nlm.nih.gov]

• Chronic Dermatitis

  In this paper 6 cases of chronic dermatitis, pruritus [jamanetwork.com]

• Neck Swelling

  Cerviral lymphadenopathy and other neck swelling, in an introduction to the symptoms and signs of surgical disease. 2nd ed. London, Arnold, 1991, pp.249-56. 5. Aird, I. [jpma.org.pk]

• Meningism

  Although uncommon, the localized form of this disease can manifest in the central nervous system, typically as a meningeal-based intracranial lesion. Castleman's disease involving the spine is exceedingly rare. [ncbi.nlm.nih.gov]

• Frontal Headache

  Abstract A 30-year-old woman, who, since the age of 20, had epileptic seizures, was hospitalized in 1972 because of frontal headaches, nausea, and vomiting. [ncbi.nlm.nih.gov]

In general clinical practice, a liver lesion workup is performed differently in different clinical backgrounds. [hindawi.com]

An evaluation of the probability of malignant causes and the effectiveness of physicians' workup. J Fam Pract. 1988;27:373–6. 5. Kelly CS, Kelly RE Jr. Lymphadenopathy in children. Pediatr Clin North Am. 1998;45:875–88. 6. [aafp.org]

A complete clinical workup of the patient was done. Laboratory investigations revealed serum bilirubin (1.1 mg/dl); direct (0.6 mg/dl); alkaline phosphatase 208 IU/L; ALT 64IU/L. [cancerjournal.net]

Intraparenchymal lymph nodes Intrapulmonary lymph nodes are often identified incidentally during imaging performed for the workup of other disorders since patients are usually asymptomatic. [pulmonologyadvisor.com]

The diagnosis of LV requires a full workup including a detailed history and a thorough physical examination. Due to its myriad forms, a high index of suspicion is the key to making the diagnosis. [oatext.com]

• Multiple Pulmonary Nodules

  Chest imaging typically reveals single or multiple pulmonary nodules or masses. Men and women are affected equally, and the median age at diagnosis is sixty-five. [pulmonologyadvisor.com]

• Hyperprolactinemia

  Endocrinologic abnormalities included decreased testosterone with elevated luteinizing hormone and follicle-stimulating hormone, as well as hyperprolactinemia and possible hypothyroidism. [ncbi.nlm.nih.gov]

• Liver Biopsy

  A liver biopsy showed sinusoidal dilatation. Fifteen months later, a computed axial tomography showed a retroperitoneal tumor that turned out to be a giant lymph node hyperplasia. [ncbi.nlm.nih.gov]

Awareness of this possibility may help avoid invasive procedures and over-treatment. Copyright 2015 Elsevier Ireland Ltd. All rights reserved. [ncbi.nlm.nih.gov]

I am suffering from smear suggestive of reactive hyperplasia of lymph node which is diagnosed by fnac test and it is in my neck This question featured in : Reactive lymphoid hyperplasia treatment Prostatic hyperplasia treatment Prostatic hyperplasia causes [practo.com]

Generalized or multicentric disease indicates a poor prognosis with short survival, with the neuropathic variant possessing resistance to steroids and chemotherapy and a corresponding worse prognosis. [ncbi.nlm.nih.gov]

[…] localized to a single group of lymph nodes (unicentric) or may involve many lymph nodes and organs containing lymphoid tissue (multicentric) Enlarged lymph nodes are a common feature of this disease, and the diagnosis is usually made by a tissue biopsy The prognosis [dovemed.com]

Abstract Angiofollicular lymph node hyperplasia is a disease of unknown etiology in which two distinct histologic forms are recognized: the hyalin vascular and the plasma-cell types. [ncbi.nlm.nih.gov]

EXPOSURES A complete exposure history is essential to determining the etiology of lymphadenopathy. [aafp.org]

Consult HON's world-wide database of medical meetings Browse - New search Refine the search for "Lupus Vulgaris" Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy Broader term [hon.ch]

Essential features Clinically manifests as lymph node enlargement No clonal process No cytologic or architectural atypia Terminology Reactive lymphoid hyperplasia Reactive follicular hyperplasia Diffuse paracortical hyperplasia Sinus histiocytosis Epidemiology [pathologyoutlines.com]

Methods Statistics Trigonometry Medical & Nursing Anatomy Anesthesiology Audiology Bacteriology Biochemistry Bioethics Biomedical Science Cardiology Cardiovascular Childbirth Chiropractic Dentistry Dermatology Diagnostic Imaging Drugs Endocrinology Epidemiology [brainscape.com]

Clinical and epidemiological observations of cutaneous tuberculosis in Larkana, Pakistan. Int J Dermatol 2002;41:159-65. 5. Tappeiner G. Tuberculosis and infections with atypical mycobacteria. [idoj.in]

An appraisal of epidemiologic, clinical, bacteriologic, histopathologic, and immunologic parameters in cutaneous tuberculosis. Int J Dermatol 1987;26:521-6. [ Links ] 12. Thomas S., Suhas S., Pai K.M., Raghu A.R. [scielo.br]

[…] intrinsic or environmental antigens Most lymph node enlargements are reactive In children, most lymphadenopathies are benign; in adults, chance of malignancy increases with age Sites Any lymph node group can be affected depending on the stimulation Pathophysiology [pathologyoutlines.com]

The aetiology and management of Castleman disease at 50 years: translating pathophysiology to patient care. Br J Haematol. 2005;129(1):3-17. [ Links ] 3. Kimura T, Inoue T, Katayama K, Hirose K, Imamura Y, Yamaguchi A. [scielo.br]

The aetiology and management of Castleman disease at 50 years: translating pathophysiology to patient care. Br J Haematol. 2005;129(1):3-17. Nishimoto N, Kanakura Y, Aozasa K, et al. [rarediseases.org]

The pathophysiology of RLH of the liver is not well understood. It was thought that reactive immune phenomena to various immune stimulants were implicated [8, 9]. [hindawi.com]

Associated infections include HIV and HHV-8, with HHV-8 thought to be involved in the pathophysiology of the disease in HIV infected patients. B. [clinicaladvisor.com]

Maintenance therapy may be required to prevent relapse. [ncbi.nlm.nih.gov]

[…] on the extent of the disease, and an individual’s response to treatment Please find comprehensive information on Castleman Disease (CD) regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention [dovemed.com]

Screening and prevention of colorectal cancer Source: Finnish Medical Society Duodecim This article is freely available only to users in the UK. [evidence.nhs.uk]

Our discussion, apoptosis, remember this is a cancer. 00:26 It will do everything in its power to upregulate anti-apoptotic factors. 00:31 So therefore, BCL-2 if upregulated prevents the release of cytochrome C from the mitochondria. 00:37 You are not [lecturio.com]