A case of giant lymph node hyperplasia presenting as a lump in the neck is reported together with a review of the literature relating to the presentation of this unusual disorder in the head and neck. [ncbi.nlm.nih.gov]

• Anemia

  The anemia was characterized by iron deficiency from selective malabsorption of iron, and by features of the anemia of chronic disorders. [ncbi.nlm.nih.gov]

• Asymptomatic

  The authors report a case of giant lymph node hyperplasia that presented as a right supraclavicular mass in an asymptomatic two-month-old female infant. [ncbi.nlm.nih.gov]

• Constitutional Symptom

  The patients presented with constitutional symptoms, multifocal lymphadenopathy, hepatomegaly, and/or splenomegaly. The laboratory findings included peripheral blood cytopenias, polyclonal hypergammaglobulinemia, and renal and hepatic dysfunction. [ncbi.nlm.nih.gov]

  Despite 10% of patients suffering constitutional symptoms such as sweating and weight loss, removal of the tumour results in very good outcome. Development of lymphoma is rare. POEMS syndrome may be present in cases of Castleman's syndrome. [gpnotebook.com]

  The majority of such patients present with constitutional symptoms. [scielo.br]

  Constitutional symptoms such as fatigue, malaise, and fever, often associated with impressive cervical lymphadenopathy and atypical lymphocytosis, are seen most commonly with mononucleosis syndromes. [aafp.org]

• Hypertension

  CASE REPORT: A 61-year old white male with weight loss and listlessness presented with moderate arterial hypertension and leukopenia. [ncbi.nlm.nih.gov]

  The patient had hypertension and osteoporosis. Fibroma and glandular lesion were the clinical hypotheses. [omicsonline.org]

• Heart Disease

  Your recognised location is United States (US) More: Guidance Coronary heart disease Source: Finnish Medical Society Duodecim This article is freely available only to users in the UK. [evidence.nhs.uk]

• Jaundice

  There was no history of fever, jaundice or pruritus and no past relevant medical history. Physical examination showed absence of pallor, icterus or any palpable lymph nodes. Right upper quadrant was tender with a positive Murphy's sign. [cancerjournal.net]

  Nakashiro H, Tokunaga O, Watanabe T, Ishibashi K, Kuwaki T (1991) Localized lymphoid hyperplasia (pseudolymphoma) of the pancreas presenting with obstructive jaundice. Hum Pathol 22: 724-726. [pancreas.imedpub.com]

• Neck Swelling

  Cerviral lymphadenopathy and other neck swelling, in an introduction to the symptoms and signs of surgical disease. 2nd ed. London, Arnold, 1991, pp.249-56. 5. Aird, I. [jpma.org.pk]

In general clinical practice, a liver lesion workup is performed differently in different clinical backgrounds. [hindawi.com]

A complete clinical workup of the patient was done. Laboratory investigations revealed serum bilirubin (1.1 mg/dl); direct (0.6 mg/dl); alkaline phosphatase 208 IU/L; ALT 64IU/L. [cancerjournal.net]

An evaluation of the probability of malignant causes and the effectiveness of physicians' workup. J Fam Pract. 1988;27:373–6. 5. Kelly CS, Kelly RE Jr. Lymphadenopathy in children. Pediatr Clin North Am. 1998;45:875–88. 6. [aafp.org]

Intraparenchymal lymph nodes Intrapulmonary lymph nodes are often identified incidentally during imaging performed for the workup of other disorders since patients are usually asymptomatic. [pulmonologyadvisor.com]

The diagnosis of LV requires a full workup including a detailed history and a thorough physical examination. Due to its myriad forms, a high index of suspicion is the key to making the diagnosis. [oatext.com]

• Human Herpesvirus 8

  Links: differential diagnosis histology POEMS syndrome human herpesvirus 8 [gpnotebook.com]

  Detection of human herpesvirus-8 in peripheral blood mononuclear cells from adult Japanese patients with multicentric Castleman’s disease. Br J Haematol. 2003;120:471-77. [rarediseases.org]

  In recent years, it’s become clear that another virus, known as human herpesvirus-8 (HHV-8) or Kaposi sarcoma herpesvirus (KSHV), is often found in the lymph node cells of people with multicentric CD. [cancer.org]

  HIV is a relevant risk factor for this condition, and it has been demonstrated that all the HIV patients with multicentric Castleman disease are coinfected with the human herpesvirus 8 (HHV-8). [radiopaedia.org]

  Over the last decade, a large body of evidence has given support to the view that infection with human herpesvirus 8 (HHV-8 or Kaposi's sarcoma-associated herpesvirus) is important in the etiology and management of CD.2 In this paper we present a patient [scielo.br]

Spine surgeons should be aware of this diagnosis as it has treatment and follow-up implications that differ from the neoplasms it can mimic. Complete surgical excision is an effective treatment for solitary lesions. [ncbi.nlm.nih.gov]

I am suffering from smear suggestive of reactive hyperplasia of lymph node which is diagnosed by fnac test and it is in my neck This question featured in : Reactive lymphoid hyperplasia treatment Prostatic hyperplasia treatment Prostatic hyperplasia causes [practo.com]

Generalized or multicentric disease indicates a poor prognosis with short survival, with the neuropathic variant possessing resistance to steroids and chemotherapy and a corresponding worse prognosis. [ncbi.nlm.nih.gov]

[…] localized to a single group of lymph nodes (unicentric) or may involve many lymph nodes and organs containing lymphoid tissue (multicentric) Enlarged lymph nodes are a common feature of this disease, and the diagnosis is usually made by a tissue biopsy The prognosis [dovemed.com]

Abstract Angiofollicular lymph node hyperplasia is a disease of unknown etiology in which two distinct histologic forms are recognized: the hyalin vascular and the plasma-cell types. [ncbi.nlm.nih.gov]

It is necessary to complete with exhaustive etiology investigation in front of this clinical presentation. [endocrine-abstracts.org]

follicular, paracortical / diffuse, sinus and mixed Etiology Multiple etiologic factors, including: Bacteria Fungi Viruses Chemicals Environmental pollutants Drugs: phenytoin, allopurinol, atenolol, gold, penicillin, quinidine Altered tissue components [pathologyoutlines.com]

Consult HON's world-wide database of medical meetings Browse - New search Refine the search for "Lupus Vulgaris" Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy Broader term [hon.ch]

Methods Statistics Trigonometry Medical & Nursing Anatomy Anesthesiology Audiology Bacteriology Biochemistry Bioethics Biomedical Science Cardiology Cardiovascular Childbirth Chiropractic Dentistry Dermatology Diagnostic Imaging Drugs Endocrinology Epidemiology [brainscape.com]

Essential features Clinically manifests as lymph node enlargement No clonal process No cytologic or architectural atypia Terminology Reactive lymphoid hyperplasia Reactive follicular hyperplasia Diffuse paracortical hyperplasia Sinus histiocytosis Epidemiology [pathologyoutlines.com]

Clinical and epidemiological observations of cutaneous tuberculosis in Larkana, Pakistan. Int J Dermatol 2002;41:159-65. 5. Tappeiner G. Tuberculosis and infections with atypical mycobacteria. [idoj.in]

An appraisal of epidemiologic, clinical, bacteriologic, histopathologic, and immunologic parameters in cutaneous tuberculosis. Int J Dermatol 1987;26:521-6. [ Links ] 12. Thomas S., Suhas S., Pai K.M., Raghu A.R. [scielo.br]

[…] intrinsic or environmental antigens Most lymph node enlargements are reactive In children, most lymphadenopathies are benign; in adults, chance of malignancy increases with age Sites Any lymph node group can be affected depending on the stimulation Pathophysiology [pathologyoutlines.com]

The aetiology and management of Castleman disease at 50 years: translating pathophysiology to patient care. Br J Haematol. 2005;129(1):3-17. Nishimoto N, Kanakura Y, Aozasa K, et al. [rarediseases.org]

The pathophysiology of RLH of the liver is not well understood. It was thought that reactive immune phenomena to various immune stimulants were implicated [8, 9]. [hindawi.com]

Associated infections include HIV and HHV-8, with HHV-8 thought to be involved in the pathophysiology of the disease in HIV infected patients. B. [clinicaladvisor.com]

The aetiology and management of Castleman disease at 50 years: translating pathophysiology to patient care. Br J Haematol. 2005;129(1):3-17. [ Links ] 3. Kimura T, Inoue T, Katayama K, Hirose K, Imamura Y, Yamaguchi A. [scielo.br]

Maintenance therapy may be required to prevent relapse. [ncbi.nlm.nih.gov]

[…] on the extent of the disease, and an individual’s response to treatment Please find comprehensive information on Castleman Disease (CD) regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention [dovemed.com]

Screening and prevention of colorectal cancer Source: Finnish Medical Society Duodecim This article is freely available only to users in the UK. [evidence.nhs.uk]

Patients with latent TB infection but no active disease may also be treated with antitubercular drugs to prevent development of active disease. See tuberculosis screening. Occasionally surgical excision of localised cutaneous TB is recommended. [dermnetnz.org]