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Lymph Node Metastasis


Presentation

  • The clinical presentation, diagnostic procedure, treatment, and outcome of this case were presented, with a review of the related literature.[ncbi.nlm.nih.gov]
Burning Pain
  • The patient was a 58-year-old man, complaints of intermittent burning pain in his both ears for 2 years, and for the recent one month the pain turn to continuous accompanied with a mild discomfort in the throat, he had neither hoarseness, dysphagia, nor[ncbi.nlm.nih.gov]
Varicella-Zoster Virus Infection
  • Abstract Herpes zoster is a reactivated varicella-zoster virus infection and demonstrates typical dermatomal distribution. We herein describe a case of a 41-year-old woman with a history of ovarian cancer.[ncbi.nlm.nih.gov]
Cervical Lymphadenopathy
  • The presence of metastatic cervical lymphadenopathy is of particular importance as with every single nodal metastasis, survival of the patient is reduced by one half.[ccij-online.org]
  • Cervical lymphadenopathy: ratio of long- to short-axis diameter as a predictor of malignancy. Br J Radiol 1995;68:266–270. 6. Leboulleux S, Girard E, Rose M, Travagli JP, Sabbah N, Caillou B, et al.[e-ultrasonography.org]
Sternoclavicular Joint Pain
  • Abstract A 73-year-old man complained of sternoclavicular joint pain; blood tests revealed elevated C-reactive protein. The patient developed delirium; magnetic resonance imaging showed metastatic bone tumors. He died two weeks after admission.[ncbi.nlm.nih.gov]
Subcutaneous Mass
  • Two subcutaneous masses of 2 cm 1 cm were found below the original incision 10 months after the operation, and regional lymphadenectomy was performed.[ncbi.nlm.nih.gov]
Subcutaneous Mass
  • Two subcutaneous masses of 2 cm 1 cm were found below the original incision 10 months after the operation, and regional lymphadenectomy was performed.[ncbi.nlm.nih.gov]
Nipple Discharge
  • The patient had intermittent, bloody nipple discharge without skin changes of the nipple-areolar region. We considered the clinical diagnosis of intraductal papilloma.[ncbi.nlm.nih.gov]
Bloody Nipple Discharge
  • The patient had intermittent, bloody nipple discharge without skin changes of the nipple-areolar region. We considered the clinical diagnosis of intraductal papilloma.[ncbi.nlm.nih.gov]
Neck Mass
  • NPC and CCUP are both with the neck mass as the first complaint, so there are relatively many CCUP patients diagnosed in our center.[onlinelibrary.wiley.com]
Vaginal Bleeding
  • We report the case of a 53-year-old woman who presented with vaginal bleeding. Clinical examination revealed a tumor sized 1.5 cm in diameter localized in the subendometrial region of the uterine wall.[ncbi.nlm.nih.gov]

Workup

  • Diagnostic workup revealed a (68)Ga-labeled prostate-specific membrane antigen-targeted ligand tracer uptaking nodule that was initially interpreted as lymph node metastasis but eventually identified as a splenunculus by scintigraphy with (99m)Tc pertechnetate-labeled[ncbi.nlm.nih.gov]
  • Take home messages Intramammary lymph node metastasis requires challenging workup There is urgent need to clarify its importance Breast Cancer patients should always undergo treatment in multidisciplinary context Consent Written informed consent from[f1000research.com]
  • Diagnostic workup and staging Diagnostic workup included complete medical history, physical examination, and hematological examination including tumor biomarker, anti‐Epstein–Barr virus antibody, and Epstein–Barr virus DNA.[onlinelibrary.wiley.com]
  • Preoperative US, neck CT, and CT-guided US were performed and reported independently for the staging workup. Each of the patients underwent surgery for thyroid papillary cancer within one month of the preoperative exam.[e-ultrasonography.org]

Treatment

  • Regional lymph node metastasis was identified after additional surgical treatment. After surgical treatment, our patient received chemotherapy consisting of etoposide and carboplatin for 3 months.[ncbi.nlm.nih.gov]

Prognosis

  • It was concluded that the preoperative NLR and PLR may be the predictors for LNM and prognosis in patients with advanced gastric cancer; nevertheless, they cannot predict LNM and prognosis in patients with EGC.[ncbi.nlm.nih.gov]

Etiology

  • Castleman disease is a rare lymphoproliferative disorder which etiology is unknown. It is divided into 2 subtypes: the plasma cell variant and the hyaline vascular variant. The most common site is the hilum of the lungs and mediastinum.[ncbi.nlm.nih.gov]
  • ., and Harris, CC (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. ‎ Page 137 - Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. ‎[books.google.com]
  • Etiology Any of the following may cause SCC: Exposure to sunlight Chemical carcinogens, such as arsenic and hydrocarbons HPV Ionizing radiation Cigarette smoke Chronic irritation or ulceration Alcohol In addition, immunocompromised patients have a much[emedicine.medscape.com]

Epidemiology

  • METHODS: Patients underwent resection and at least one lymph node examined were identified from the Surveillance, Epidemiology, and End Results database.[ncbi.nlm.nih.gov]
  • Textbook of Cancer Epidemiology. 2th ed. Oxford University Press; 2008. Mendonça GA, Silva AM, Caula WM. [Tumor characteristics and five-year survival in breast cancer patients at the National Cancer Institute, Rio de Janeiro, Brazil].[acm.org.br]
  • Oral squamous cell carcinoma: Epidemiology, clinical presentation and treatment. J Cancer Ther 2012;3:263-8. 4. World Health Organization. Control of oral cancer in developing countries. A WHO meeting. Bull World Health Organ 1984;62:817-30. 5.[amsjournal.com]
  • International Journal of Epidemiology, 39 (2), 598–610. doi: 10.1093/ije/dyp392. CrossRef PubMed Google Scholar 12. Benson, J. R., & della Rovere, G. Q. (2007). Management of the axilla in women with breast cancer.[doi.org]
  • Global epidemiology. In: Shah JP, Johnson NW, Batsakis JG, editors. Oral Cancer. London: Martin Dunitz Publication; 2003. 2. Divya MR, Nagesh KS, Iyengar AR, Gupta J, Reddi NS. Recent advances in the treatment of oral cancer: An overview.[ccij-online.org]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology [ edit ] Metastatic tumors are very common in the late stages of cancer. The spread of metastasis may occur via the blood or the lymphatics or through both routes.[en.wikipedia.org]

Prevention

  • However, whether undergoing prophylactic central lymph node (CLN) dissection or lateral lymph node (LLN) dissections to prevent metastasis is still controversial.[ncbi.nlm.nih.gov]
  • For decades, the oncology community has focused on adjuvant therapies in an effort to prevent distant metastasis.[cancerres.aacrjournals.org]

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