Presentation
Residual nodes were present in 10% of patients at the end of 9-month treatment with rifampicin, isoniazid and ethambutol, including prolonged or modified regimens in some individuals. [ncbi.nlm.nih.gov]
Entire Body System
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Fever
[…] extrapulmonary tuberculosis that is located in lymph node, and has symptom lymphadenopathy, has symptom fever, has symptom weight loss, has symptom fatigue, has symptom night sweats and has symptom cough Tuberculous cervical lymphadenitis Lymph Node Tuberculosis [wikidata.org]
Sweet's syndrome (SS) is an acute neutrophilic dermatosis characterised by abrupt onset of fever, leukocytosis and cutaneous eruption, with dermal neutrophilia on skin biopsy. [ncbi.nlm.nih.gov]
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Chills
A 21-year-old man came to our hospital with persistent pain in his right lower quadrant of abdomen for more than 1 month, but had no diarrhea, fever, chills, weight loss, or other constitutional symptoms. [ncbi.nlm.nih.gov]
NTM infections do not show other notable constitutional symptoms, but scrofula caused by tuberculosis is usually accompanied by other symptoms of the disease, such as fever, chills, malaise and weight loss in about 43% of the patients. [en.wikipedia.org]
They include: A cough that lasts more than 3 weeks Chest pain Coughing up blood Feeling tired all the time Night sweats Chills Fever Loss of appetite Weight loss If you experience any of these symptoms, see your doctor to get tested. [webmd.com]
Immune System
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Cervical Lymphadenopathy
After one month of antituberculous treatment, the cervical lymphadenopathy and left parotid lumpiness disappeared. Tuberculous parotitis and neoplasms have similar clinical manifestations. [ncbi.nlm.nih.gov]
Imaging alone is often unable to categorically distinguish tuberculous lymphadenitis from other causes of cervical lymphadenopathy and necrotic/cystic lymphadenopathy. [radiopaedia.org]
Recent statistics for NTM indicate an increase in prevalence and isolation of cervical lymphadenopathy caused by NTM. Because NTM is not generally reportable, the true incidence is difficult to determine. [emedicine.com]
Directly observed treatment short course in immunocompetent patients of tuberculous cervical lymphadenopathy treated in revised national tuberculosis control programme. [journal.frontiersin.org]
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Inguinal Lymphadenopathy
We present a case report and a review of literature of isolated tubercular inguinal lymphadenopathy presenting as acute lymphadenitis, which is even rarer. [ispub.com]
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Abdominal Lymphadenopathy
Tuberculosis abdominal lymphadenopathy causing reversible renovascular hypertension. JAPI 2000 ; 48 : 530-2. 15. Hewlett D Jr, Duncanson FP, Jagadha V, Lieberman J, Lenox TH, Wormser GP, et al. [lungindia.com]
Gastrointestinal
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Abdominal Pain
We report the case of a 38 year old Pakistani man with abdominal pain of several months duration, who was initially diagnosed with a pancreatic neoplasm after detecting a mass in the pancreatic isthmus by computed tomography (CT) and abdominal magnetic [ncbi.nlm.nih.gov]
Pain 542 Celiac Disease 543 Pancreatitis 544 Cholecystitis 546 Endocrine System 548 Thyroid Disorders 551 Adrenal Disorders 557 Puberty and Gonadal Disorders 563 Growth Disorders 567 Pituitary Disorders 572 Type 1 InsulinDependent Diabetes Mellitus 573 [books.google.com]
Case presentation A 23-year-old Japanese man presented to our hospital with lower abdominal pain. He showed no symptoms such as fever, weight loss, night sweats or anorexia. [jmedicalcasereports.biomedcentral.com]
pain, and other nontypical symptoms. [journals.lww.com]
Symptoms can include: persistently swollen glands abdominal pain pain and loss of movement in an affected bone or joint confusion a persistent headache fits (seizures) TB affecting other parts of the body is more common in people who have a weakened immune [nhs.uk]
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Nausea
Clinically, the symptoms of abdominal TB lymphadenitis are varied and nonspecific, and include abdominal pain, fever, weight loss, abdominal mass, jaundice, nausea, vomiting, and diarrhea. [sonoworld.com]
Feeling sick (nausea). Itching. Feeling generally more unwell. If you have any of these, stop the tablets and see a doctor urgently. Vision changes (if taking ethambutol). Early symptoms are slight loss of vision or loss of colour vision. [patient.info]
Four patients developed mild pruritus to ATT which responded to antihistamines and two patients developed nausea to ATT which responded to antiemetics ( Figure 14 ). Figure 14: Adverse drug reactions to ATT. [omicsonline.org]
Jaw & Teeth
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Parotid Swelling
Parotid gland Mycobacterial infection is a rare disease that causes parotid swelling without disease-specific manifestations. We present a case of intraparotid lymph node tuberculosis that mimicked a tumour. [ncbi.nlm.nih.gov]
Skin
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Delayed Wound Healing
1 Fine needle non-aspiration cytology for the diagnosis of cervical lymph node tuberculosis: a single center experience. ( 30017875 ) 2018 2 High IL-6 and VEGF-A levels correlate with delayed wound healing in cervical lymph node tuberculosis patients. [malacards.org]
Breast
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Breast Mass
At the end of this treatment, she was also investigated for a breast mass that proved to be benign; however, enlarged lymph nodes were discovered in the right armpit were discovered upon further investigation. [ncbi.nlm.nih.gov]
Face, Head & Neck
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Neck Mass
After diagnosis, all patients received antituberculous chemotherapy and one patient with pocket formation underwent total resection of neck masses with infectious skin. [jstage.jst.go.jp]
Examination found a large neck mass (8 cm by 5 cm) but was otherwise unremarkable. [bmj.com]
PPD should be the first line of investigation in the workup of a patient with a neck mass. Usefulness is diminished in individuals who have immunosuppression secondary to anergy. For nontuberculous mycobacterium (NTM), response is variable. [emedicine.com]
A 39-year-old Zambian man who was visiting the United States presented with a three-week history of a draining neck mass and a three-month history of swelling on the left side of his neck. [nejm.org]
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Cellulitis of the Face
Of the 35 patients treated with surgery and chemotherapy, two had gaping wounds, one infection and one cellulitis of the face and neck. [ncbi.nlm.nih.gov]
Workup
PPD should be the first line of investigation in the workup of a patient with a neck mass. Usefulness is diminished in individuals who have immunosuppression secondary to anergy. For nontuberculous mycobacterium (NTM), response is variable. [emedicine.com]
Chronic LD: Suggested Initial Workup 1. Complete blood counts, erythrocyte sedimentation rate, and a careful evaluation of the peripheral blood smear. ( 5, 15, 22, 26 ). 2. [journal.frontiersin.org]
X-Ray
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Left Pleural Effusion
One year later, the CT scan showed increased left axillary lymph nodes and a left pleural effusion. Direct and cultural examinations to exclude tuberculosis were again negative. [ncbi.nlm.nih.gov]
Treatment
Nine other patients had changes in treatment because of side-effects (5), drug-resistant organisms (3) and pregnancy (1). Treatment was prolonged in another seven patients, four in error and three because of previous drug treatment. [ncbi.nlm.nih.gov]
Prognosis
The prognosis of Scrofula is very good with appropriate treatment Please find comprehensive information on Scrofula regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, [dovemed.com]
[…] citation needed ] The affected nodes can be removed either by repeated aspiration, curettage or total excision (with the risk in the latter procedure, however, often causing unsightly scarring, damage to the facial nerve, or both). [ citation needed ] Prognosis [en.wikipedia.org]
Treatment and prognosis Treatment is with prolonged courses of multi-agent antimycobacterials and in some instances (after many months of medical management) surgical excision of residual nodal masses 6. [radiopaedia.org]
For example, in cancers, the condition of lymph nodes is significant for cancer staging, which decides the treatment to be employed and the prognosis. [thehealthsite.com]
Prognosis When taking treatment for tuberculosis in Norway, you will be cured. Normally, you will be called for check-ups for up to two years after you completed treatment. [lhl.no]
Etiology
Materials and Methods: Study included patients aged 6 years with peripheral lymphadenopathy of tubercular etiology attending a tertiary care hospital from Jan 2010 to Dec 2010. [ncbi.nlm.nih.gov]
Head Trauma 234 Sepsis and Septic Shock 242 Nonpolio Enteroviruses 332 Respiratory Syncytial Virus 334 Rhinoviruses 336 Roseola and Human Herpesviruses 337 Rubella 338 Rubeola 339 VaricellaZoster Virus 342 Viral Gastroenteritis 344 Disorders of Unknown Etiology [books.google.com]
Its diagnosis in this unusual site highlights the fact that migration is an etiologic factor not only in terms of migration from developing to developed countries but also migration within a developing country itself. [sciforschenonline.org]
Upregulation of PSME2 in LNTB tissue, thus, implicates a similar role of gene in diseases with related etiologies. ATP6V1B2 encodes a component of vacuolar ATPase (V-ATPase). [nature.com]
Etiology of Scrofula Cellular immunity, in particular the T-cell population, is instrumental in controlling infection. [emedicine.com]
Epidemiology
CONCLUSION: Most of the differences in the clinical presentation among patients from various geographic areas were driven by the epidemiology of TB and HIV in the countries of origin. [ncbi.nlm.nih.gov]
Epidemiological data were extracted from the hospital electronic database and medical records. [journals.plos.org]
There are many important changes incorporated into this edition, including the dramatic effect of AIDS on the incidence and clinical mani festations of mycobacterial infection, new developments in epidemiology and bacteriology, and thoroughly updated [books.google.com]
Most of the differences in the clinical presentation among patients from various geographic areas were driven by the epidemiology of TB and HIV in the countries of origin. [em-consulte.com]
Pathophysiology
Pathophysiology of Scrofula Mycobacterium tuberculosis is an obligate aerobe, non–spore-forming, slender rod. Humans are its only reservoir. Transmission is from person to person via respiratory route by inhalation of small aerosols. [emedicine.com]
Pathophysiology Mycobacterium tuberculosis is most commonly spread via the respiratory route by inhalation of infected aero-sols. [heartlandntbc.org]
Prevention
Centers for Disease Control and Prevention (CDC) 1600 Clifton Rd. [dovemed.com]
We should consider tuberculosis when cervical lymph node swelling is seen, and early diagnosis and treatment are needed to prevent the spread of infection to others. [jstage.jst.go.jp]
As with the first edition, it is hoped that this text will continue to represent a definitive resource for both the basic scientist and the clinician who deal with the prevention and treatment of mycobacterial infection. [books.google.com]
Lymph node biopsy and adequate histopathological assessment would have prevented these misdiagnoses and should be mandatory in suspected cases of lymph node tuberculosis when microscopy and cytology of fine needle aspirate does not show alcohol and acid [bmj.com]