Keywords Lymphoblastic lymphoma, Precursor-B cell, Skeletal involvement at presentation Introduction Lymphoblastic lymphoma (LL) of the B cell type is uncommon, and extranodal presentation is even rarer. [amhsr.org]

Here we present a case of hypothalamic obesity syndrome as the primary presentation of a toddler found to have CNS+ B-cell lymphoblastic lymphoma. Cytogenetic studies on diagnostic cerebrospinal fluid revealed MLL gene rearrangement (11q23). [ncbi.nlm.nih.gov]

Patients with precursor T-cell lymphoblastic lymphomas usually present with lymphadenopathy and mediastinal mass. Pleural effusion may be present. [cureus.com]

• Severe Clinical Course

  Despite the severe clinical course, the patient recovered and was discharged with only residual symptoms. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. [ncbi.nlm.nih.gov]

• Diplopia

  CASE REPORT: A 12-year-old boy presented with worsening left-sided weakness, nausea, vomiting, headache, blurred vision, and diplopia. Magnetic resonance imaging revealed right parietal gyral thickening with faint meningeal contrast enhancement. [ncbi.nlm.nih.gov]

• Subcutaneous Nodule

  Subcutaneous nodules located on the head or neck of infants should raise suspicion for lymphoma and biopsy should be performed in order to rule out malignancy. A prompt diagnosis is imperative when considering the aggressive nature of LBLs. [ncbi.nlm.nih.gov]

• Eczema

  Patches are usually flat, possibly scaly, and look like a rash; plaques are thicker, raised, usually itchy lesions that are often mistaken for eczema, psoriasis, or dermatitis; and tumors are raised bumps, which may or may not ulcerate. [lymphoma.org]

METHODS: In this review, we summarize the cases discussed during the workshop, review the pertinent and most recent literature on the respective topics, and provide a few key points that may aid in the workup of patients with B-ALL/LBL. [ncbi.nlm.nih.gov]

She was given supportive care and detailed lab workup was started. [cureus.com]

• Ovarian Mass

  A 15-year-old girl presented with bilateral ovarian masses, which, on biopsy proved to be precursor B-cell lymphoblastic lymphoma. [ncbi.nlm.nih.gov]

Treatments Chemotherapy is the main treatment for lymphoblastic lymphomas. Some people may also be offered radiation therapy or a stem cell transplant. [cancer.ca]

Treatment schedule was based on the previous, LSA2-L2 derived, AIEOP LNH-92 protocol. [ncbi.nlm.nih.gov]

Patients sometimes present with respiratory emergency; pleural effusions can also occur • Patients with T-ALL present with large mediastinal or other tissue masses with a high leukocyte count Prognosis and treatment • Prognosis of T-LBL depends on the [doctorlib.info]

t(12;21)(p13;q22) TEL-AML1 (ETV6-RUNX1); blasts with hyperdiploidy (50 - 66 chromosomes with no structural alterations) Poor prognosis: t(9;22)(q34;q11.2) BCR-ABL1; t(v;11q23) MLL rearranged; blasts with hypodiploidy (< 46 chromosomes); t(1;19)(q23; [pathologyoutlines.com]

The prognosis of the condition is guarded and is evaluated on a case-by-case basis Typically for Lymphoblastic Lymphoma, if all of the following prognostic indicators are noted, then the prognosis is worse. [dovemed.com]

Attempt to make a preoperative diagnosis is crucial because ovarian NHL responds well to chemotherapy and has a good prognosis. [ncbi.nlm.nih.gov]

We describe the case of an infant with primary cutaneous B-cell LBL who was initially diagnosed by a primary care physician with an infectious etiology and consequently treated with topical and oral antibiotics. [ncbi.nlm.nih.gov]

Definition / general Pre B lymphoblastic leukemia is defined as 20% or more lymphoblasts in bone marrow Terminology Disorder of immature B cells that usually affects children, and often presents with diffuse multiorgan involvement Etiology Derived from [pathologyoutlines.com]

Conversely, a diagnosis of ALL requires at least 20% lymphoblasts in marrow. [2] Etiology and Pathophysiology Lymphoblastic lymphoma is associated with exposure to radiation or pesticides and congenital or acquired immunosuppression and is more common [emedicine.medscape.com]

(Etiology) Lymphocytes are a type of white blood cells that are responsible for providing immunity in the human body. B-cells and T-cells are the two different types of lymphocytes. [dovemed.com]

The aim of the present analysis was to characterize the clinical features and histologic subtypes and to assess the clinical prognostic factors for 696 adult patients with LL, the largest epidemiologic sample to date. [ncbi.nlm.nih.gov]

Epidemiology B-ALL is predominantly a disease of childhood (75% of cases <6 years old). B lymphoblastic lymphoma constitutes ~10% of cases of lymphoblastic lymphoma and 75% of cases are less than 18 years old. [e-immunohistochemistry.info]

As a result, the true number of women with lipedema, or its epidemiology, is unknown. [lipedema.org]

[…] peripheral blood and bone marrow involvement is extensive, the term acute lymphoblastic leukemia (T-ALL) is used Pathogenesis • T-cell progenitor or thymic lymphocytes are considered the normal counterparts for T-ALL and T-LBL, respectively Clinical features Epidemiology [doctorlib.info]

Haematology (51) Internal Medicine (51) Pathology and Forensic Medicine (48) Oncology, Radiation Therapy (35) Physiology and Pathophysiology (27) Paediatrics, Neonatology (17) Medical Chemistry and Biochemistry (16) Surgery, Traumatology and Orthopaedics [portal.mefanet.cz]

Pathophysiological dilemmas of lipedema. Med Hypotheses. 2014;83:599–606. CrossrefPubMedGoogle Scholar [4] Fife CE, Maus EA, Carter MJ. Lipedema: a frequently misdiagnosed and misunderstood fatty deposition syndrome. [degruyter.com]

IBS continues to be a therapeutic challenge because of its diverse symptomatology and lack of a single pathophysiological target for drug intervention. [kiss.kstudy.com]

The underlying pathophysiology of large fat cells and surrounding hyaluronic acid and water can also be found in diabetes, therefore studying the fat in either condition is crucial. [obesityaction.org]

Primary testicular lymphoblastic B cell lymphoma is an aggressive disease and it is necessary a multimodal therapy (surgery, chemotherapy and radiotherapy) to prevent metastasis. [ncbi.nlm.nih.gov]

CNS prophylaxis may be given to prevent lymphoma cells from spreading to the brain and spinal cord. [cancer.ca]

Some of these cells include red blood cells which carry oxygen, platelets which are used to form blood clots and prevent bleeding, and white blood cells whose function is to fight infection. [cumc.columbia.edu]

(Korean J Med 2014;86:664-672) 다운로드 (기관인증 필요) 초록보기 Antiplatelet therapies have been widely used to prevent cardiovascular diseases. [kiss.kstudy.com]