Presentation
Three of these four cases with lymphocytic gastritis presented an endoscopic diagnosis of enanthematous pangastritis, and one presented erosive pangastritis. [ncbi.nlm.nih.gov]
[…] loss and anorexia (Gut 1990;31:282) Cases associated with Ménétrier disease may present with protein losing enteropathy (Hum Pathol 1991;22:379) Diagnosis Established by gastric biopsy Case reports 2 year old child autopsy findings after presenting with [tistorysjloveu2.tistory.com]
Entire Body System
- Asymptomatic
Some individuals may not exhibit any symptoms (asymptomatic). Common symptoms that do occur include nausea, vomiting, diarrhea and pain in the upper middle region of the stomach (epigastric pain). [rarediseases.org]
Relationship of Helicobacter pylori to serum pepsinogens in an asymptomatic Japanese population. Gastroenterology. 1992 Mar. 102(3):760-6. [Medline]. Sugiyama T, Nishikawa K, Komatsu Y, et al. [emedicine.medscape.com]
Both gastritis and gastropathy may be clinically asymptomatic. [cmej.org.za]
Our patient, after jejunostomy creation and starting of enteral nutrition, was asymptomatic, and so, in April 2016, hormone therapy with fulvestrant was started (500 mg, day 0, 14, and 28 and every 28 days thereafter by intramuscular injection). [hindawi.com]
- Surgical Procedure
This is a minor surgical procedure where a sample of affected lymph node tissue is removed and studied in a laboratory. [nhs.uk]
Learning about the patient's past medical history, focusing on any prior issues or surgical procedures. Clarifying the patient's current medication regimen, including prescriptions, over-the-counter medications, and supplements. [en.wikipedia.org]
Massive growth of yeast organisms in the gastric lumen (yeast bezoar) is a potential complication of gastric surgical procedures, usually for peptic ulcer disease. [clinicalgate.com]
- Sepsis
[…] carcinoma Gastroduodenal ulcer Intoxication Liver failure Lymphocytic gastritis Mallory-Weiss Tear Menetrier's Disease Pancreas carcinoma Pancreatitis Peptic ulcer Perforated ulcer Radiation Reflux esophagitis Renal Failure Respiratory failure Sarcoidosis Sepsis [wikidoc.org]
However, regular use can lead to gastritis.[27] Additionally, severe physiologic stress ("stress ulcers") from sepsis, hypoxia, trauma, or surgery, is also a common etiology for acute erosive gastritis. [en.wikipedia.org]
Gastrointestinal
- Vomiting
A 7-year-old spayed female domestic shorthair cat was referred for chronic intermittent vomiting. The frequency of vomiting increased recently, and the cat showed anorexia at presentation. [dbpia.co.kr]
An obstruction further down in the intestine or colon will cause delayed vomiting. [en.wikipedia.org]
Patients with persistent nausea, vomiting, and anorexia after day 20 underwent upper intestinal endoscopy and mucosal biopsy. [ncbi.nlm.nih.gov]
World J Surg Oncol 2017 ; 15 : 123. 2 Just scratching the surface: intractable nausea and vomiting. Am J Med 2015 ; 128 : e3 – 5. 3, et al. Scirrhous gastric carcinoma: endoscopy versus upper gastrointestinal radiography. [academic.oup.com]
- Gastropathy
Lymphocytic gastritis has recently been reported to be associated with other forms of hypertrophic gastropathies. We present a case of hypertrophic gastropathy with gastric adenocarcinoma, with both Menetrier's disease and lymphocyte gastritis. [ncbi.nlm.nih.gov]
Reactive gastropathy / chemical gastritis Includes most acute gastritis Various causes including: Alcohol NSAIDS and other drugs Bile and/or duodenal contents (alkaline) reflux Frequently post-surgical Chronic gastritis and chronic active gastritis Non-atrophic [surgpathcriteria.stanford.edu]
- Nausea
Patients with persistent nausea, vomiting, and anorexia after day 20 underwent upper intestinal endoscopy and mucosal biopsy. [ncbi.nlm.nih.gov]
World J Surg Oncol 2017 ; 15 : 123. 2 Just scratching the surface: intractable nausea and vomiting. Am J Med 2015 ; 128 : e3 – 5. 3, et al. Scirrhous gastric carcinoma: endoscopy versus upper gastrointestinal radiography. [academic.oup.com]
When symptoms of gastritis do occur, they include abdominal pain or discomfort and sometimes nausea or vomiting. [merckmanuals.com]
- Abdominal Pain
[…] location of abdominal pain can provide information about what may be causing the pain. [en.wikipedia.org]
pain and iron deficiency anemia have been reported but presenting symptoms are variable (Pathol Case Rev 2008;13:167) Predominately recurrent vomiting, epigastric pain or chronic diarrhea is seen in pediatric patients (J Pediatr 1994;124:57) Cases associated [tistorysjloveu2.tistory.com]
However, the patient with gastritis usually presents with vague recurrent upper abdominal pain or discomfort, whereas in pancreatitis there is severe persistent pain of recent onset.Chronic pancreatitis is rare in your age group, but it can occur. [xsnygv.ga]
You should see a doctor if you have any of the following: Blood when you have a bowel movement Severe abdominal pain Heartburn not relieved by antacids Unintended weight loss Ongoing vomiting or diarrhea NIH: National Institute of Diabetes and Digestive [icdlist.com]
During her initial presentation, she initially was given an empiric trial of dicylcomine with improvement in pain. Subsequently, she presented to an emergency room due to abdominal pain, where a CT scan was done. [healio.com]
- Diarrhea
We have evaluated simultaneous small bowel and gastric biopsies from 22 patients with diarrhea or malabsorption, all of which showed small bowel changes characteristic of sprue or spruelike disease. [ncbi.nlm.nih.gov]
[…] vSlideID 1496 Diagnosis Lymphocytic gastritis Topography Stomach StainHaematoxylin & Eosin (H&E) Age32 years Sexfemale Clinical findingsFemale patient reporting recurrent episodes of diarrhea. In addition, she suffers from weight loss. [pathorama.ch]
You should see a doctor if you have any of the following: Blood when you have a bowel movement Severe abdominal pain Heartburn not relieved by antacids Unintended weight loss Ongoing vomiting or diarrhea NIH: National Institute of Diabetes and Digestive [icdlist.com]
This patient had reported watery diarrhea while on olmesartan (Benicar), an angiotensin two receptor inhibitor. Figure 2.139 Lymphocytic/collagenous gastritis pattern, olmesartan. [doctorlib.info]
The patient did not have watery diarrhea. Collagenous gastritis can occur in young patients, be restricted to the stomach, and can be associated with celiac disease. Collagenous Gastritis. [sites.google.com]
Liver, Gall & Pancreas
- Jaundice
Physical examination upon admission revealed no anemia (via conjunctival pallor examination), jaundice or pulmonary abnormalities. On palpation, the abdomen of the patient was soft and flat, with no areas of tenderness. [spandidos-publications.com]
Symptoms of liver lymphoma are often mild and non-specific and may include: Extreme fatigue Pain or swelling in the upper right abdomen Loss of appetite Nausea and vomiting Jaundice (yellowing of the skin and/or eyes) Dark urine Unintended weight loss [verywellhealth.com]
Skin
- Ulcer
This diagnosis should be considered in cases of diffuse gastric ulceration with bleeding in which the endoscopic appearances are not typical of peptic ulcer disease or drug-induced erosions. [ncbi.nlm.nih.gov]
"), burns ("Curling ulcer"), or severe infections.[1] Diet[edit] Evidence does not support a role for specific foods including spicy foods and coffee in the development of peptic ulcers.[20] People are usually advised to avoid foods that bother them.[ [en.wikipedia.org]
Some patients develop ulcers or hypoproteinemia. The stomach appears normal or it may present with thickened gastric folds, often with multiple discrete mucosal nodules, ulcers, erosions, or elevations measuring 3 to 10mm in diameter. [humpath.com]
Neurologic
- Confusion
There is considerable confusion and contradiction in the medical literature regarding disorders involving large gastric folds. GHG is often used as a synonym for Menetrier disease. However, Menetrier disease is not a true form of gastritis. [rarediseases.org]
Get medical help right away if any of the following occur: vomiting blood rapid heartbeat difficulty breathing or swallowing extreme drowsiness passing out suddenly confusion Chronic gastritis puts you at risk for bleeding in your stomach and small intestine [healthline.com]
Some people confuse lymphoma with back pain. Lymph nodes can also swell during common infections, such as a cold. In lymphoma, the swelling does not resolve. Pain is also more likely to accompany the swelling if it has occurred due to an infection. [medicalnewstoday.com]
Rare ADRs include: headache, tiredness, dizziness, confusion, diarrhea, constipation, and rash.[5] In addition, gynecomastia occurred in 0.1% to .5% of men treated for nonhypersecretory conditions with cimetidine for 1 month or longer and in about 2% [en.wikipedia.org]
Moreover, many of the symptoms will be non-specific and easily confused with other, less serious diseases. Even so, there are tell-tale clues to watch out for if you think you may have lymphoma or have a family history of the disease. [verywellhealth.com]
Workup
A morphologic diagnosis of LG should prompt clinical and serologic workup to exclude underlying CD. © 2014 John Wiley & Sons Ltd. [ncbi.nlm.nih.gov]
A morphologic diagnosis of Lymphocytic gastritis should prompt clinical and serologic workup to exclude underlying celiac disease ] [histopathology-india.net]
Provides all the necessary tools to make a comprehensive diagnostic workup including data from ancillary techniques and molecular findings whenever appropriate. [books.google.com]
The mucosa can, however, also appear normal, which requires high clinical suspicion in further workup. The antrum and pylorus are most commonly involved in LP, while the fundus is the least involved. [cancertherapyadvisor.com]
[…] complete blood count, urine pregnancy test followed with quantitative blood beta-hCG Imaging: transvaginal ultrasound If patient is unstable: IV fluid resuscitation, urgent obstetrics and gynecology consultation If patient is stable: continue diagnostic workup [en.wikipedia.org]
Serum
- Lymphocytosis
When restricted to cases with lymphocytosis alone, LG is strongly associated with CD and not with active H. pylori infection. [ncbi.nlm.nih.gov]
The lymphocytosis may be patchy so that different biopsies may vary in the intensity of the intraepithelial lymphocytosis. [humpath.com]
Most cases show expansion of the lamina propria with a mixed lymphoplasmacytic inflammatory infiltrate, in addition to the intraepithelial lymphocytosis (Fig. 2.121). [doctorlib.info]
- Lymphocytes Increased
Increased intraepithelial lymphocytes Increased intraepithelial lymphocytes, expanded lamina propria Biopsy from area of nodular gastric mucosa Positive stains Lymphocytes are predominately CD3 positive T cells with CD8 co-expression Sample pathology [pathologyoutlines.com]
Increased intraepithelial lymphocytes Increased intraepithelial lymphocytes, expanded lamina propria Biopsy from area of nodular gastric mucosa Positive stains Lymphocytes are predominately CD3 positive T cells with CD8 co-expression Sample pathology [tistorysjloveu2.tistory.com]
Microbiology
- Helicobacter Pylori
Influence of Helicobacter pylori. 61 Cabral VL...Miszputen SJ 19017282 2009 [malacards.org]
Helicobacter pylori in peptic ulcer disease. NIH Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease. JAMA. 1994 Jul 6. 272(1):65-9. [Medline]. Shiotani A, Nurgalieva ZZ, Yamaoka Y, Graham DY. Helicobacter pylori. [medscape.com]
pylori (Hp) and celiac disease (CD). [hindawi.com]
Although Helicobacter pylori is typically undetectable in LyG, patients respond to H. pylori antibiotic eradication therapy, suggesting a non-H. pylori microbial trigger for the disease. [ncbi.nlm.nih.gov]
Colonoscopy
- Colitis
[…] with collagenous gastritis and celiac disease, collagenous sprue has been seen in patients with collagenous colitis, lymphocytic colitis, lymphocytic gastritis, and ulcerative jejunitis. [medical-dictionary.thefreedictionary.com]
PMID: 10029639 Mar 1999 A novel enteropathy with partial villous atrophy, microscopic colitis, and pemphigoid change. PMID: 2661662 April 1989 Collagenous colitis and microscopic colitis: the watery diarrhea-colitis syndrome. [sites.google.com]
위염 또는 위장염 Eosinophilic gastritis or gastroenteritis K528 림프구성 결장염 Lymphocytic colitis K528 현미경적 결장염(콜라젠성 결장염 또는 림프구성 결장염) Microscopic colitis(collagenous colitis or lymphocytic colitis) K529 상세불명의 비감염성 위장염 및 결장염 Noninfective gastroenteritis and colitis [druginfo.co.kr]
No evidence of lymphocytic or collagenous colitis was found in the colon. The patient became symptom-free on a gluten exclusion diet and showed partial improvement of histopathologic findings after 3 months. [ncbi.nlm.nih.gov]
Lymphocytic colitis was common (38%, 5 of 13) in celiac disease with LG. Our results indicate that lymphocytic gastritis most commonly occurs in celiac disease and HP infection, but rarely with other entities. [mayoclinic.pure.elsevier.com]
- Polyps
The mucosal elevations persist after the erosions heal, resembling sessile hyperplastic polyps. The disorder affects the entire stomach. Somepatients develop hypertrophic lymphocytic gastritis. [humpath.com]
The book describes and illustrates the distinguishing features of non-neoplastic lesions, polyps, and neoplasms of the esophagus, stomach, small intestine, colon, and anus. [books.google.com]
In 84 patients (82%), a distinct associated entity was identified, including 39 with celiac disease, 30 with HP infection, 4 with varioliform gastritis, 2 each with inflammatory polyp, Crohn's disease, human immunodeficiency virus infection, lymphoma, [ncbi.nlm.nih.gov]
Other Pathologies
- Lymphocytic Infiltrate
Intraepithelial lymphocytes in small bowel and stomach were positive for the antibody MT-1, indicating a T-cell infiltrate at both sites. [ncbi.nlm.nih.gov]
Treatment
The patients histologically H pylori positive before treatment became H pylori negative. Dyspepsia scores also improved significantly after treatment. [ncbi.nlm.nih.gov]
Prognosis
There are many different types of non-Hodgkin's lymphoma, and the prognosis depends on the specific diagnosis. Prognosis can also vary within the same subtype. [everydayhealth.com]
In addition, they reviewed novel techniques that may help improve prognosis determination. [cancertherapyadvisor.com]
[…] lymphocytes/100 epithelial cells) Subtypes primary (idiopathic), secondary LM DDx Helicobacter gastritis, Crohn's disease, lymphoma Site stomach Associated Dx celiac disease (common), HIV Clinical history dependent on underlying cause Prevalence rare Prognosis [librepathology.org]
Prognosis Gastric LP has a very poor prognosis due to the frequent occurrence of peritoneal dissemination, lymphatic invasion and extension toward neighboring organs. The 5-year survival rate is around 10-20% in Japan and Europe. [orpha.net]
The prognosis of NHL depends on the specific type. Explore the links on this page to learn more about lymphoma treatment, research, and clinical trials. [cancer.gov]
Etiology
H. pylori appears to be one etiological cause of lymphocytic gastritis. [ncbi.nlm.nih.gov]
[…] associations include celiac disease (Am J Surg Pathol 1999;23:153) Also associated with HIV infection, Crohn disease, Ménétrier disease, NSAIDs and lymphocytic or collagenous colitis Unknown etiology in up to 20% of cases (Am J Surg Pathol 1999;23:153 [tistorysjloveu2.tistory.com]
In approximately 20% of cases, the etiology is unknown. Some patients develop ulcers or hypoproteinemia. [humpath.com]
Epidemiology
주요논문 Epidemiological Correlation between Fecal Adenovirus Subgroups and Pediatric Intussusception in Korea [ JOURNAL OF KOREAN MEDICAL SCIENCE ] - 2017.10.01 소아에서의 헬리코박터 연관 림프구성 위염 [ PEDIATRIC GASTROENTEROLOGY, HEPATOLOGY & NUTRITION ] - 2014.09.30 CD4 [medulsan.ac.kr]
Summary Epidemiology Gastric LP accounts for about 10% of all gastric cancers but the exact prevalence in the general population is unknown. [orpha.net]
[…] endoscopic mucosal appearance of small nodules with central erosions and enlarged rugal folds) appears to represent a subset of lymphocytic gastritis (J Pathol 1989;158:19) ICD coding ICD-10: K52.89 - other specified noninfective gastroenteritis and colitis Epidemiology [tistorysjloveu2.tistory.com]
"Epidemiology of salivary gland infections". Oral and Maxillofacial Surgery Clinics of North America. 21 (3): 353–357. doi:10.1016/j.coms.2009.05.004. ISSN 1558-1365. PMID 19608052. [en.wikipedia.org]
Pathophysiology
Helicobacter pylori did not seem to play a role in the pathophysiology. Lymphocytic duodenitis was found in four patients. The relationship between lymphocytic gastritis, Ménétrier's disease and coeliac disease has further to be elucidated. [ncbi.nlm.nih.gov]
[…] endoscopic mucosal appearance of small nodules with central erosions and enlarged rugal folds) appears to represent a subset of lymphocytic gastritis (J Pathol 1989;158:19) ICD coding ICD-10: K52.89 - other specified noninfective gastroenteritis and colitis Pathophysiology [pathologyoutlines.com]
HIV/AIDS Crohn's disease (Crohn gastritis) Celiac disease ( lymphocytic gastritis ) [3] connective tissue disorders liver failure kidney failure Pathophysiology [ edit ] Chronic gastritis is a progressive, life-long inflammation. [en.wikipedia.org]
[…] setting (Pediatr Dev Pathol 2011;14:280) Sites Antral predominance or diffuse involvement may be associated with celiac disease (J Clin Pathol 1999;52:815) Corpus predominance may be associated with H. pylori infection (Am J Surg Pathol 1999;23:153) Pathophysiology [tistorysjloveu2.tistory.com]
Prevention
Prevention The widespread detection and treatment of H. pylori as a preventive measure in gastritis has been discussed but not resolved. [encyclopedia.com]
Preventing lymphoma There are no proven measures to prevent lymphoma, except potentially the avoidance of causes such as HIV infection. Source Understanding Non-Hodgkin Lymphoma, Cancer Council NSW ©2015. [cancer.org.au]
If you are diagnosed with lymphoma, talk with your doctor about whether joining a clinical trial is right for you. back to top Is Lymphoma Preventable? Because the cause of lymphoma remains unknown, there is no real way to prevent it. [hematology.org]
Cancer vaccine targets under evaluation in lymphoma clinical trials include: Personalized neoantigens: these abnormal proteins arise from mutations and are expressed exclusively by tumor cells Survivin: a protein that can prevent cellular death and is [cancerresearch.org]
This helps to prevent oedema (swelling due to excess fluid) and keeps the fluid levels in the body and the bloodstream within normal limits. To absorb fats from the digestive system. [lymphoma.org.au]