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Lymphocytic Myocarditis


Presentation

  • A patient with Whipple's disease presented with a long prodromal period characterized by granulomatous lymphadenitis and progressive lymphedema of the extremities.[ncbi.nlm.nih.gov]
  • VCAM-1 was also present on 50% (P 0.05) of the samples from the 5 patients with acute myocarditis, but was not present in those with non-specific cardiomyopathy.[ncbi.nlm.nih.gov]
  • Lymphocytic myocarditis, an immune disorder of left ventricular dysfunction with sometimes confounding clinical presentations, occurs rarely during pregnancy.[ncbi.nlm.nih.gov]
  • Cardiac autoantibodies were present in 19 responders (90%) and in none of the nonresponders.[ncbi.nlm.nih.gov]
  • Diagnosing lymphocytic myocarditis (LM) is challenging because of the large variation in clinical presentation and the limitations inherent in current diagnostic tools.[ncbi.nlm.nih.gov]
Congestive Heart Failure
  • Despite vigorous antithyroid treatment including a beta-blocker, glucocorticoid and potassium iodide, the patient eventually succumbed to refractory congestive heart failure in 4 days. Autopsy revealed lymphocytic myocarditis.[ncbi.nlm.nih.gov]
  • A 23-year-old woman developed congestive heart failure and severe left ventricular dysfunction 32 months after a bilateral lung allograft for cystic fibrosis.[ncbi.nlm.nih.gov]
  • No patient had congestive heart failure.[ncbi.nlm.nih.gov]
  • Overall mortality and morbidity from congestive heart failure was assessed at 28 days.[ncbi.nlm.nih.gov]
Heart Disease
  • A 14-year-old boy without overt heart disease underwent encircling ventriculotomy and cryoablation because of ventricular tachycardia resistant to antiarrhythmic therapy.[ncbi.nlm.nih.gov]
  • In two of them, ventricular tachycardia was identified by mass screening for heart disease. Two patients received oral steroids and two received pulse steroid therapy.[ncbi.nlm.nih.gov]
  • The other 6 had ECG abnormalities identified by mass screening for heart disease, and subsequently had been histologically diagnosed as having non-specific cardiomyopathy.[ncbi.nlm.nih.gov]
  • Additionally, medical procedures such as electrical cardioversion, and long-lasting illnesses such as kidney disease and heart disease, can cause high levels of troponin in the blood.[aviationtravelwriter.wordpress.com]
  • He is a Consultant in the Division of Cardiovascular Diseases, specializing in the areas of pulmonary hypertension, valvular heart disease, and hospital coronary care.[books.google.com]
Tachycardia
  • We conclude that unexplained ventricular tachycardia may be the only manifestation of clinically silent myocarditis.[ncbi.nlm.nih.gov]
  • A 14-year-old boy without overt heart disease underwent encircling ventriculotomy and cryoablation because of ventricular tachycardia resistant to antiarrhythmic therapy.[ncbi.nlm.nih.gov]
  • Ventricular tachycardia/fibrillation could not be provoked in the laboratory during repeat electrophysiologic testing in five of the six patients.[ncbi.nlm.nih.gov]
  • Here, we report a 46-year-old woman who presented with hyperpyrexia and sinus tachycardia subsequent to accidental neck contusion. Her hyperthyroidism was verified by abnormal biochemical changes.[ncbi.nlm.nih.gov]
  • This report describes the case of a 33-year-old woman with biopsy-proven, active lymphocytic myocarditis manifested by intractable ventricular tachycardia, nonspecific intraventricular block, and myocardial dysfunction.[ncbi.nlm.nih.gov]
Cardiomegaly
  • Cardiomegaly with biatrial enlargement. Abnormal hyperintense signals involving the myocardium on T2 DIR, as compared to the skeletal muscle, the ratio is 3:1 . Early enhancement when comparedT1 DIR pre to post contrast.[radiopaedia.org]
  • […] growth of the ventricles what patient demographic is most likely to get hypertrophic cardiomyopathy male patients 20-50 years old what gross and histological changes are seen in hypertrophic cardiomyopathy Gross: Lack of LV compliance, LA dilation, cardiomegaly[quizlet.com]
Cardiac Signs and Symptoms
  • The book and DVD package is designed to provide comprehensive coverage of every aspect of cardiovascular medicine from cardiac signs and symptoms and the full range of cardiac imaging techniques through management of peripheral vascular disease and the[books.google.com]
Contusion
  • Here, we report a 46-year-old woman who presented with hyperpyrexia and sinus tachycardia subsequent to accidental neck contusion. Her hyperthyroidism was verified by abnormal biochemical changes.[ncbi.nlm.nih.gov]

Workup

T Wave Inversion
  • Markers of myocardial damage ( troponin or creatine kinase cardiac isoenzymes) are elevated. [10] The ECG findings most commonly seen in myocarditis are diffuse T wave inversions; saddle-shaped ST-segment elevations may be present (these are also seen[en.wikipedia.org]

Treatment

  • In survivors, left ventricular function in myocarditis improved approximately 10% over 6 months without immunosuppressive treatment. Prednisone alone did not improve survival (P 0.2) or left ventricular function (P 0.11).[ncbi.nlm.nih.gov]
  • We chose to study the epidemiologic grounds and all major aspects of differential pathogenesis and treatment of this serious health problem.[ncbi.nlm.nih.gov]
  • Despite vigorous antithyroid treatment including a beta-blocker, glucocorticoid and potassium iodide, the patient eventually succumbed to refractory congestive heart failure in 4 days. Autopsy revealed lymphocytic myocarditis.[ncbi.nlm.nih.gov]
  • With the use of these histologic criteria, the endomyocardial biopsy may be helpful in the detection of active myocarditis and in the evaluation of treatment.[ncbi.nlm.nih.gov]
  • Holmes Springer Science & Business Media , 06.12.2007 - 2926 Seiten 0 Rezensionen Cardiovascular Medicine, 3rd Edition offers the most up-to-date, user-friendly guidance on the evaluation, diagnosis and medical and surgical treatment of heart and vascular[books.google.com]

Prognosis

  • Routine measurement of CRP may be a useful tool for determining the prognosis in patients with LM.[ncbi.nlm.nih.gov]
  • Heart transplantation (HT) for myocarditis has been controversial because of earlier reports of a poor prognosis after the procedure.[ncbi.nlm.nih.gov]
  • In general, the long-term prognosis in myocarditis is favorable but exercise stress may cause long-term sequelae or sudden death. It is thus essential to refrain from strenuous exercise during RTI.[ncbi.nlm.nih.gov]
  • This disease in contrast to fulminant myocarditis carries a poor prognosis. Treatment should include steroids with immunosuppressive therapy including cyclosporine and/or azathioprine that significantly improves prognosis 8.[escardio.org]
  • The late cardiac prognosis after Coxsackie-B infection. Acta Med Scand 1968;183:235–237. PubMed CrossRef Google Scholar 4. Bowles NE, Richardson PJ, Olsen EG, Archard LC.[link.springer.com]

Etiology

  • Pathology by systems Cardiovascular system Heart lymphocytic myocarditis Sunday 9 January 2005 Etiology direct infection Viral infection Bacterial infection Bartonella henselae myocarditis postinfectious autoimmune reaction E.[humpath.com]
  • […] pathophysiology, what is the clinical presentation, what is the pathological presentation, what are the potential outcomes what: rare, fatal myocarditis patient: adults 20-50 etiology: unknown, but most likely autoimmune clinical: sudden onset heart[quizlet.com]
  • […] has been suggested for GCM, based on the antimyosin GCM Lewis rat model and a high prevalence of associated autoimmune disorders, especially inflammatory bowel disease Diagrams / tables Images hosted on other servers: Etiology of Myocarditis Clinical[pathologyoutlines.com]
  • Etiology From an etiologic perspective, myocarditis cases usually fall into 1 of the following 4 main categories: Infectious Postviral autoimmune-related Autoimmune-mediated (lupus myocarditis, giant-cell myocarditis [GCM]) Drug-associated (hypersensitivity[emedicine.medscape.com]
  • Myocarditis of unknown etiology (Fiedler’s ?) treated with ACTH: report of a case in a 7-year-old boy with improvement. J Pediatr 1953;42:591–599. PubMed CrossRef Google Scholar 2. Ainger LE. Acute aseptic myocarditis: corticosteroid therapy.[link.springer.com]

Epidemiology

  • We chose to study the epidemiologic grounds and all major aspects of differential pathogenesis and treatment of this serious health problem.[ncbi.nlm.nih.gov]
  • He has since completed further training in emergency medicine, clinical toxicology, clinical epidemiology and health professional education.[lifeinthefastlane.com]
  • […] encefalo - mielita evolutie severa cu - insuficienta cardio-respiratorie 323h79d 323h79d 323h79d 323h79d 323h79d 323h79d 323h79d 323h79d - pareze, paralizii 323h79d 323h79d 323h79d 323h79d 323h79d 323h79d 323h79d 323h79d 323h79d - coma DIAGNOSTIC Å Ü - epidemiologic[scritub.com]
  • […] eosinophilic and giant cell myocarditis (GCM) Terminology GCM has been termed idiopathic GCM, pernicious myocarditis, Fiedler myocarditis, acute idiopathic interstitial myocarditis, giant cell granulomatous myocarditis, and granulomatous myocarditis Epidemiology[pathologyoutlines.com]
Sex distribution
Age distribution

Pathophysiology

  • […] time what is the typical pathological presentation of lymphocytic myocarditis Gross: Flabby, dilated heart Microscopic: T cell infiltrate with myocyte necrosis what is lymphocytic myocarditis, what type of patient is it common in, what is the etiology/pathophysiology[quizlet.com]
  • […] myocarditis, Fiedler myocarditis, acute idiopathic interstitial myocarditis, giant cell granulomatous myocarditis, and granulomatous myocarditis Epidemiology Incidence difficult to determine as most cases are believed to be subclinical or underdiagnosed Pathophysiology[pathologyoutlines.com]
  • The present article will focus on the discussion of pathophysiological insights, indications, and options for myocardial biopsy, considering existing guidelines for biopsy ( 4 ) and the therapeutic options in acquired myocardial disorders based thereon[aerzteblatt.de]

Prevention

  • […] dangerous and life-threatening situation: in particular, the inflammation of the myocardial tissue of the heart may lead to severe consequences since the clinical history of the disease may be completely asymptomatic, any clinical sign may be lacking, thus preventing[ncbi.nlm.nih.gov]
  • […] comprehensive coverage of every aspect of cardiovascular medicine from cardiac signs and symptoms and the full range of cardiac imaging techniques through management of peripheral vascular disease and the genetic basis for cardiovascular disease to preventive[books.google.com]
  • An immunosuppressant compound, FK-506, prevents the progression of autoimmune myocarditis in rats. Clin Immunol Immunopathol 1992;62:321–326. PubMed CrossRef Google Scholar 32. McManus BM, Han L, Caruso R, Stratta RJ, Wilson JE.[link.springer.com]
  • Prevention There's no specific prevention for myocarditis. However, taking these steps to prevent infections might help: Avoid people who have a viral or flu-like illness until they've recovered.[mayoclinic.org]
  • Página 487 - Diphtheria, tetanus, and pertussis: recommendations for vaccine use and other preventive measures. Recommendations of the Immunization Practices Advisory Committee (ACIP). ‎[books.google.es]

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