Edit concept Question Editor Create issue ticket



  • Abstract A 36 year old woman presented with malabsorption and macroamylasemia. The macroamylase was characterized and shown to be a complex of pancreatic amylase and immunoglobulin A(IgA).[ncbi.nlm.nih.gov]
  • This syndrome is presented in a patient with cholecystitis and a partial small bowel obstruction accompanied by persistent pre- and postoperative hyperamylasemia with proven macroamylasemia.[ncbi.nlm.nih.gov]
  • Hyperamylasemia was not present at the diagnosis of myeloma and appeared at the relapse of the disease, simultaneously with the appearance of an additional gamma-chain oligoclonal component, suggesting a possible role of these chains in producing macroamylasemia[ncbi.nlm.nih.gov]
  • CASE REPORT: Authors presented their own clinical observation of a young woman who was diagnosed to have macroamylasemia on the background of splenosis due to the splenectomy after blunt abdominal injury.[ncbi.nlm.nih.gov]
  • MAIN FINDINGS: The patient is a 31-year-old G2P1 who presented to the ob/gyn triage with the complaint of recurrent right-sided abdominal pain. Serum amylase values were elevated.[ncbi.nlm.nih.gov]
  • URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services.[lutheranhealthcare.org]
Chronic Abdominal Pain
  • CASE REPORT: An 11-year-old girl was referred for chronic abdominal pain and growth retardation associated with persistent hyperamylasemia and suspected chronic pancreatitis.[ncbi.nlm.nih.gov]


  • This disorder should be considered in a patient with asymptomatic hyperamylasemia because its detection can obviate a prolonged diagnostic workup. The condition requires no treatment and may be transient.[ncbi.nlm.nih.gov]
Amylase Increased
  • Amylase increases may occur postoperatively, resulting in increased S-type and P-type isoamylases; however, an increase in salivary amylase is more common.[emedicine.medscape.com]


  • However, in the presence of symptoms, especially of abdominal origin, it is important that this condition be identified accurately in order to avoid unnecessary treatment for pancreatitis or other related diseases.[ncbi.nlm.nih.gov]
  • On the other hand, acute pancreatitis is a serious illness demanding recognition and treatment. Persistently normal pancreatic scans convincingly exclude acute pancreatitis and should alert one to the possible presence of macroamylasemia.[ncbi.nlm.nih.gov]
  • The condition requires no treatment and may be transient. Macroamylasemia is one of several immunoglobulin-complexed enzyme (ICE) disorders. MacroLDemia, an ICE disorder of lactate dehydrogenase (LD), shares features with macroamylasemia.[ncbi.nlm.nih.gov]
  • Significant updates on bariatric surgery, Barrett's esophagus, endoscopic ultrasound, endosonography, treatment of liver disease, and much more keep you current on the latest advances.[books.google.ro]


  • The Grey Turner sign (ecchymoses of the flanks) and the Cullen sign (ecchymoses of the umbilical region) indicate extravasation of hemorrhagic exudate, occur in 1% of cases, and portend a poor prognosis.[msdmanuals.com]


  • Abstract CONTEXT: Article analyzes current data on macroamylasemia and splenosis, their etiology and diagnostics in particular.[ncbi.nlm.nih.gov]
  • Only one patient had family history of macroamylasemia, but 2 patients had relatives with elevated amylase of unknown etiology.[omicsonline.org]
  • Particular attention has been devoted to the manage ment of the more difficult therapeutic problems such as severe protracted pancreatitis, pancreatitis of unknown etiology, pancreatic pseudocyst, and pancreatic insufficiency.[books.google.ro]
  • This is the best test to use when the etiology of hyperamylasemia is obscure. Ref: iMedicine 2002 03192002[enotes.tripod.com]


  • Linguistic Variant - Portuguese, Brazil) 2015AB LNC-RU-RU (LOINC Linguistic Variant - Russian, Russia) 2015AB LNC-TR-TR (LOINC Linguistic Variant - Turkish, Turkey) 2015AB LNC-ZH-CN (LOINC Linguistic Variant - Chinese, China) 2015AB MCM (Glossary of Clinical Epidemiologic[doctor.am]
Sex distribution
Age distribution


  • Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 58. Updated by: Michael M.[medlineplus.gov]
  • Molecular and Systemic Pathophysiology Amylase is an extracellular digestive enzyme that acts to cleave starch into di- and monosaccharides. The active cytoplasmatic form contains 496 amino acids with a molecular weight of around 54 kDa.[link.springer.com]
  • Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 58. Text only Tests for Macroamylasemia Reviewed By: Michael M.[leehealth.org]
  • Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 58. Tests for Macroamylasemia Reviewed By: Michael M.[huronregional.org]
  • Keywords Amylases; Creatine Kinase; macroamylase INTRODUCTION A distinctive characteristic of macroenzymes is a molecular mass higher than that of the corresponding enzymes normally found in serum under physiological or pathophysiological conditions [[pancreas.imedpub.com]


  • Abstract Macroamylasemia is a condition characterized by a serum amylase activity increase due to complex macromolecules whose large size prevents its urinary excretion.[ncbi.nlm.nih.gov]
  • Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection.[books.google.ro]
  • Differential diagnosis in this case would have prevented unnecessary and expensive treatment for pancreatitis and spared stress to the patient caused by the pancreatitis misdiagnosis.[degruyter.com]
  • Other possible ways to prevent infection of necrotizing pancreatitis include selective digestive tract decontamination and use of enteral rather than parenteral feeding.[randyamy.com]
  • NCI_CTEP-SDC (Cancer Therapy Evaluation Program - Simple Disease Classification) 2015AB NCI_CareLex (Content Archive Resource Exchange Lexicon) 2015AB NCI_DCP (NCI Division of Cancer Prevention Program) 2015AB NCI_DICOM (Digital Imaging Communications[doctor.am]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!