Twelve patients (57%) had nerve territory-oriented macrodactyly, whereas 9 (43%) presented with lipomatous type. [ncbi.nlm.nih.gov]

• Surgical Procedure

  The surgical procedures which may be utilized for this problem are numerous, ranging from ablation of the digit as a primary surgical procedure to numerous defatting procedures combined with other techniques. [ncbi.nlm.nih.gov]

• Soft Tissue Mass

  Six patients underwent resection of the proximal phalanges together with bulk reduction of the soft tissue mass. Only soft tissue reduction was performed in the remaining two patients. [ncbi.nlm.nih.gov]

• Camping

  Furthermore, it was identified that GRIN3A and MAPT were regulated by the cAMP‑protein kinase A and extracellular signal‑regulated kinase 1/2 pathways, respectively. [ncbi.nlm.nih.gov]

• Suggestibility

  These facts suggest that this case of macrodactyly was sustained by an underlying disorder, namely, a "forme fruste" of neurofibromatosis, implying the existence of a still unknown pathogenetic mechanism. [ncbi.nlm.nih.gov]

In the case reported here, debulking combined with a shortening osteotomy was the treatment of choice. [ncbi.nlm.nih.gov]

Macrodactyly associated with Proteus syndrome should be distinguished from other forms of macrodactyly because of its poor prognosis and high rate of recurrence. [ncbi.nlm.nih.gov]

Abstract Macrodactyly or megalodactyly is a rare congenital malformation of essentially unknown etiology. Treatment of this affliction is generally surgical and is dependent on the type of growth rate of the enlarged digit. [ncbi.nlm.nih.gov]

The specific nerve pathophysiology in this form of macrodactyly has not been well described and a genetic etiology for this specific form of enlargement is unknown. [ncbi.nlm.nih.gov]

Although it is difficult to compare treatment regimens, epiphysiodesis/epiphysectomy was quite effective in the prevention of longitudinal overgrowth of the digits, but resection of the hypertrophic nerves was unsuccessful in preventing finger overgrowth [ncbi.nlm.nih.gov]