Presentation
In this study, we present a consanguineous family with three affected brothers, in whom we have identified a homozygous mutation in the spermatogenesis-specific gene SPATA16. [ncbi.nlm.nih.gov]
Volume should be more than 2 ml. motility Shows how many moving sperm are present. This aspect is vital to enabling the sperm unites with the egg in the Fallopian tube. [bostonivf.com]
In Figure 47-2, several similar examples are presented. In Patient A, the effective sperm count was 30,000/cc. In Patient B, the ESC was 116,850/cc and in Patient C, the ESC was 50,000/cc. [naprotechnology.com]
Because sperm development takes over 2 months, illness that was present during the first cycle may affect mature sperm, regardless of a man's health at the time of examination. [healthcommunities.com]
Presently, there are no proven therapies to correct an abnormal DNA integrity test result. [auanet.org]
Entire Body System
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Severe Pain
If you experience bleeding heavier than a menses, severe pain or temperature greater than 100.4, please call the office. Male fertility treatments can involve surgical procedures. [floridafertility.com]
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Rigor
Sperm and washing medium are combined and spun rigorously (centrifuged) and the process is repeated if necessary. The process separates sperm from white blood cells and fatty acids (prostaglandins) in the semen that may hinder sperm motility. [centerforurologiccare.com]
Skin
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Sparse to No Body Hair
This condition, which is caused by an extra X chromosome, results in infertility, sparse facial and body hair, abnormal breast enlargement (gynecomastia), and smaller than normal testes. [centerforurologiccare.com]
Ears
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Low Set Ears
These individuals are characterized by short stature, webbed neck, low-set ears, and cardiovascular abnormalities. Other chromosomal abnormalities include myotonic dystrophy, bilateral anorchia, sertoli-cell-only syndrome. [ucdenver.edu]
Neurologic
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Confusion
Male infertility should not be confused with erectile dysfunction, which is the inability to get or keep an erection long enough for sex and usually is treatable. [uabmedicine.org]
Two thirds of male patients don't know they're sterile because doctors use confusing language when diagnosing infertility rather than giving the facts, said Barnes. They use metaphors like “engines” and “baseball,” she added. [abcnews.go.com]
“Guys confuse libido and potency with fertility. They get worried that they will be stereotyped.” [webmd.com]
Male Infertility There is no more confused medical care in our field than what is delivered by many urologists to the couple that suffers from “male infertility.” [infertile.com]
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Meningism
meningitis, syphilis, mumps) Isolated LH deficiency (e.g., fertile eunuch syndrome) Radiation Testicular trauma Tumors of the pituitary gland, hypothalamus, or testicles To learn more about testosterone deficiency including symptoms, diagnosis, and [centerforurologiccare.com]
Workup
Our male infertility workup includes an in-depth look at the male partner’s medical history, a physical exam, and a Semen Analysis test. [bostonivf.com]
See Workup for more detail. [emedicine.medscape.com]
Computer-Assisted Routine Semen Analysis The semen analysis provides the most comprehensive assessment of semen quality and is considered the foundation of the basic infertility workup of a couple. [my.clevelandclinic.org]
Treatment
Home » Fertility Treatments Fertility Treatments - Step by Step Almost 60% of couples are able to conceive with these types of Fertility treatments suggesting that the majority of couples are able to conceive with basic fertility treatment interventions [floridafertility.com]
[…] cases where the above treatments are unsuccessful, or when the cause of male infertility is unknown or untreatable, IUI treatment or IVF treatment may be suggested. [infertility.about.com]
The treatments below are broken into 3 categories: Non-surgical therapy for Male Infertility Surgical Therapy for Male Infertility Treatment for Unknown Causes of Male Infertility Non-Surgical Treatment for Specific Male Infertility Conditions Many male [urologyhealth.org]
At MFS we offer the following treatments: Spinal Cord Injury Treatments Electroejaculation Therapy (EEJ) Hormone Deficiency Treatments Clomiphene Citrate (Clomid, Serophene) For Unexplained Low Sperm Count For Genetic Defects Varicocele Ligation Sperm [malefertility.md]
Today, there is much hope for male infertility treatment. Using high-tech treatments alongside commonsense lifestyle changes, you and your partner can benefit from the best treatments that let you get pregnant—and start your family. [attainfertility.com]
Prognosis
Prognosis With improvements in technology, the prognosis for infertile couples has changed from discouraging to quite promising. [drugs.com]
This treatment may be necessary as globozoospermic sperm can be less likely to activate the oocyte, an important stage in fertilisation.The treatment options currently available focus on overcoming the prognosis of infertility which is associated with [en.wikipedia.org]
Whilst a low sperm count is a poor prognostic feature, and the lower the count the worse the prognosis, it is not totally incompatible with fertility. A number of genetic disorders may be associated with infertility. [patient.info]
It used to be thought that these men could never father children and had the worst prognosis of any male infertility. In truth, most of these cases have been successful in our hands. [infertile.com]
Ultrastructural pathology of the sperm flagellum: association between flagellar pathology and fertility prognosis in severely asthenospermic men. Hum. Reprod., 1998, 13, 9: 2521–2526. 14. [bacandrology.biomedcentral.com]
Etiology
For couples who are having problems conceiving, approximately 40% of the time the etiology is related to the male partner. In another 20% of cases a combination of both male and female factors are responsible. [nashvillefertility.com]
See all Hide authors and affiliations Science Translational Medicine 13 Aug 2014: Vol. 6, Issue 249, pp. 249ra108 DOI: 10.1126/scitranslmed.3009071 Abstract Genital tract infection and reduced sperm motility are considered two pivotal etiological factors [stm.sciencemag.org]
Male infertility is estimated to represent about 20% of the etiologies. Among them, a rare type of teratozoospermia known as globozoospermia leads to disappointing pregnancy outcomes. [ncbi.nlm.nih.gov]
[…] a surgical or idiopathic etiology Male infertility. [emedicine.medscape.com]
Epidemiology
Epidemiology 6 (1995): 282-8. Schover, Leslie. Overcoming Male Infertility: Understanding Its Causes and Treatments. New York: John Wiley & Sons, 2000.Shaw, Gina. [livestrong.org]
Pathophysiology
Léandri, Sperm morphology: assessment, pathophysiology, clinical relevance, and state of the art in 2017, Andrology, 5, 5, (845-862), (2017). E. Moretti, N. A. Pascarelli, G. Belmonte, T. Renieri and G. [doi.org]
Pathophysiology Gonadal and sexual functions are mediated by the hypothalamic-pituitary-gonadal axis, a closed-loop system with feedback control from the testicles. [emedicine.medscape.com]
Prevention
Can male infertility be prevented? There is usually nothing that can be done to prevent male infertility caused by genetic problems or illness. However, there are actions that men can take to decrease the possibility of infertility. [americanpregnancy.org]
Vasectomy Varicocele Sperm production problems Ejaculatory disorders These prevent sperm from reaching the female. [resolve.org]
Can male infertility be prevented or avoided? You cannot always prevent male infertility. However, there are factors that can affect this condition that you should avoid. [familydoctor.org]
Many types of male infertility aren't preventable. [mayoclinic.org]
In men, hormone disorders; illness; reproductive anatomy, trauma, and obstruction; and sexual dysfunction can temporarily or permanently affect sperm and prevent conception. [healthcommunities.com]