Presentation
We report here a patient with adenocarcinoma of the lung who, after declining chemotherapy and radiotherapy, presented with tumour response following self-administration of cannabidiol, a non-psychoactive compound present in Cannabis sativa. [cannabis-med.org]
The only exception is when the patient presents solely for administration of chemotherapy, immunotherapy, or radiation therapy. [hcpro.com]
[…] before the discovery of the primary tumor. [3] In contrast to other orbital metastases, breast carcinoma can have a bilateral presentation in up to 15-20% of cases. [eyewiki.aao.org]
Case presentation A 58-year-old premenopausal female with underlying diseases of Chiari I malformation with syringomyelia C1-T10 levels presented to the outpatient surgical unit in a Thai provincial hospital. [dovepress.com]
Entire Body System
- Lymphedema
More common but less serious ones include skin burns, irritation or discoloration, fatigue, and lymphedema. Some types of hormone therapy lower estrogen levels in women, and increase the risk for osteoporosis. [healthline.com]
NLN: Position Statement Paper by the National Lymphedema Network: Lymphedema Risk Reduction Practices. May 2010. Accessed 8/31/20. 3. [msdmanuals.com]
[…] sentinel node biopsy radiation modified radical mastectomy resection of nipple, entire breast, pectoralis minor, and level I-II axillary nodes level III axillary nodes removed if involved complications long thoracic nerve damage results in winged scapula lymphedema [medbullets.com]
We evaluate secondary lymphedema that results from anticancer therapy for breast cancer under 13.10E if the lymphedema is treated by surgery to salvage or restore the functioning of an upper extremity. [ssa.gov]
Respiratoric
- Pleural Effusion
INTRODUCTION The first step in the etiological investigation of a pleural effusion is to determine whether the effusion is a transudate or an exudate. [scielo.br]
Pleural effusion, ascites, pathological fracture, and spinal compression can occur with advanced disease. interventions The treatment of choice is resection of the lump with removal of varying amounts of surrounding healthy tissue, ranging from a margin [medical-dictionary.thefreedictionary.com]
Musculoskeletal
- Back Pain
Felt upper back pain and numbness of Left arm 5 Consulted at a private clinic. FNAB was done showing malignant cells. Advised surgery. 1 mo PTA – Sought second opinion at PGH. Slide review done. Mammogram requested. [slideplayer.com]
Eyes
- Blurred Vision
Women should promptly report certain symptoms to their doctor: Any changes in their breasts Pain Loss of appetite or weight Changes in menstruation Bleeding from the vagina (if not associated with menstrual periods) Blurred vision Any symptoms that seem [msdmanuals.com]
Breast
- Nipple Discharge
Another symptom is bloody nipple discharge if the tumor is positioned beneath the nipple, which is the case in 50 percent of papillary carcinomas. [breasthealthandhealing.org]
[…] changes, no nipple discharge Left: 3.5x4.5cm firm slightly tender slightly moveable mass at the 11 o clock direction 10 cm from the nipple, no axillary nodes, no skin and nipple changes, no nipple discharge 14 Cardio vascular: Adynamic precordium, distinct [slideplayer.com]
discharge Physical exam firm immobile, painless lump some skin changes redness, ulcerations, edema, and nodularity axillary lymphadenopathy in more advanced cases breast skin edema with dimpling ( peau d' orange ) represents obstruction of the lymphatics [medbullets.com]
Women should still be familiar with their normal breast tissue and report any changes in appearance, size, or feel of the tissue or nipples, or any nipple discharge to their health care provider. [oncolink.org]
Common examples include: N63 – Unspecified lump in breast N64.52 – Nipple discharge N64.4 - Mastodynia R92.0 – Mammographic microcalcification found on diagnostic imaging of breast R92.1 – Mammographic calcification found on diagnostic imaging of breast [rccb.org]
- Breast Mass
Signs and symptoms Characteristics Benign Malignant Breast mass – a dominant mass is a distinct mass that is asymmetric with the other breast. Benign findings are often associated with cysts, fibroadenomas, or fibrocystic changes. [pathophys.org]
The breast mass was initially misdiagnosed as invasive ductal carcinoma. [nature.com]
This is in contrast to ICD-9-CM, where lumps and masses are reported with code 611.72 ( Lump or mass in breast ), but nodule is reported with code 793.89 [ Other (abnormal) findings on radiological examination of breast ]. [rccb.org]
We describe an MGCT that presented as a right breast mass in a 79-year-old Japanese woman. Local excision was performed for the primary tumor, which was diagnosed as an atypical GCT, but 15 months later, the tumor recurred at the same site. [link.springer.com]
A mass detected by breast self-examination, clinical breast examination, or mammogram requires follow-up. Ultrasonography helps distinguish cysts from a solid mass. [medical-dictionary.thefreedictionary.com]
- Mastodynia
Common examples include: N63 – Unspecified lump in breast N64.52 – Nipple discharge N64.4 - Mastodynia R92.0 – Mammographic microcalcification found on diagnostic imaging of breast R92.1 – Mammographic calcification found on diagnostic imaging of breast [rccb.org]
Workup
She was diagnosed as AML - M2 in the year 2007 after a complete workup. She was treated with the standard induction chemotherapy regimen of 3 + 7 daunomycin and cytarabine. [ccij-online.org]
Patients require a systemic workup to evaluate for metastases to other organ systems, and a multidisciplinary team including oncology, radiation oncology, and ophthalmology are necessary. [eyewiki.aao.org]
Immunohistochemical studies are often employed in the workup of spindle cell lesions of breast, especially in the group with a monophasic pattern. The most important task is to exclude the potential diagnosis of metaplastic CA. [sigmaaldrich.com]
(See Workup.) Increased public awareness and improved screening have led to earlier diagnosis, at stages amenable to complete surgical resection and curative therapies. [emedicine.medscape.com]
Pleura
- Pleural Effusion
INTRODUCTION The first step in the etiological investigation of a pleural effusion is to determine whether the effusion is a transudate or an exudate. [scielo.br]
Pleural effusion, ascites, pathological fracture, and spinal compression can occur with advanced disease. interventions The treatment of choice is resection of the lump with removal of varying amounts of surrounding healthy tissue, ranging from a margin [medical-dictionary.thefreedictionary.com]
Treatment
Radiation treatments used to last for several weeks, but advances in radiation treatments has lead to very targeted treatments that may only take one week. [knowcancer.com]
Often different types of treatment are used together to achieve the best result. [hopkinsmedicine.org]
Talk to your doctor to determine the best course of treatment for your situation. [webmd.com]
Treatment-related leukemia typically occurs in the first 10 years after treatment after which risk tapers a little. [ccij-online.org]
Prognosis
Prognosis The prognosis for people with breast tumors depends largely on the size, type and staging of the tumor. When detected early enough, the prognosis for people with breast tumors is generally very good. [knowcancer.com]
These differences often affect prognosis. Tumor characteristics, such as hormone receptor status and HER2 status, also affect prognosis. Learn more about factors that affect prognosis. [ww5.komen.org]
Prevention, and Complications Prognosis lymph node involvement is the single most important prognostic factor TNM staging extranodal metastases has more significance than lymph node metastasis Prevention mammography effective screening tool except in [medbullets.com]
The prognosis of Paget’s disease depends on the prognosis of the underlying carcinoma. [med-ed.virginia.edu]
Larger primary tumor: Larger tumors are more likely to be node-positive, but they also confer a worse prognosis independent of nodal status. High-grade tumor: Patients with poorly differentiated tumors have a worse prognosis. [msdmanuals.com]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
ICD-10-CM Codes › C00-D49 Neoplasms › C50-C50 Malignant neoplasms of breast › Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]
The detection of high-oncogenic HPV genotypes in patients with breast cancer supports the hypothesis of an etiologic role for the virus in breast cancer development. [ncbi.nlm.nih.gov]
[…] factor: Treatment-related, syndromic, and due to shared etiologic influences. [8] Although a causal link has not been proven, these neoplasms are thought to be a direct consequence of mutational events caused by cytotoxic therapy. [ccij-online.org]
The etiology of MPMTs remains unclear. [journals.plos.org]
Epidemiology
Introduction Epidemiology breast cancer is the most common cancer and second most common cause of death in adult women Risk factors BRCA1 and BRCA2 mutations associated with multiple / early onset breast and ovarian cancer other genetic relationships [medbullets.com]
An analysis of Surverllance, Epidemiology, and End Results Program Data. Cancer 68: 2069–2073. pmid:1913556 View Article PubMed/NCBI Google Scholar 15. [journals.plos.org]
The international variation in breast cancer rates: an epidemiological assessment. Breast Cancer Res Treat. 1991 May. 18 Suppl 1:S11-7. [Medline]. Kaaks R. Nutrition, hormones, and breast cancer: is insulin the missing link?. [emedicine.medscape.com]
The predominance of females among patients with cancer observed in the present study is in contrast to international epidemiological data. [scielo.br]
Epidemiology Age: There is a steady increase in the incidence of breast cancer, as women grow older. The age-specific incidence rate is highest in postmenopausal women. [med-ed.virginia.edu]
Pathophysiology
Breast Cancer Pathophysiology Breast cancer is a malignant tumor that starts in the cells of the breast. Like other cancers, there are several factors that can raise the risk of getting breast cancer. [news-medical.net]
Types of invasive breast carcinoma include ductal, lobular, and mixed. [5] Pathophysiology To date, the basis for breast carcinoma as the most common primary metastatic process to the orbit is unclear. [eyewiki.aao.org]
Pathophysiology The current understanding of breast cancer etiopathogenesis is that invasive cancers arise through a series of molecular alterations at the cell level. [emedicine.medscape.com]
Prevention
Related information Information for Health Professionals – Recommendations on Prevention and Screening for Breast Cancer Cancer Prevention Series 4 – Breast Cancer Prevention and Screening For further information about women's health, please visit the [chp.gov.hk]
Unfortunately, cost sometimes prevents women from choosing breast-conserving surgery. [stopcancerfund.org]
Preventive surgery is an option for women at high risk. [medicalnewstoday.com]
Papillary Breast Cancer Treatment Local therapy is aimed at preventing the cancer from coming back in the breast. Local therapy includes surgery (lumpectomy or mastectomy), and may include radiation. [hopkinsmedicine.org]
Preventive surgery. Women with a very high risk of breast cancer may choose to have their healthy breasts surgically removed (prophylactic mastectomy). [mayoclinic.org]