We present four cases and a brief review of the literature to highlight HSP in the differential diagnosis of patients who present with any of the typical clinical signs and symptoms. [ncbi.nlm.nih.gov]

The mortality rate in patients who present with hematochezia is only 19 percent, compared with 83 percent in patients with any other presenting symptom. [aafp.org]

Bowel obstruction or perforation may result in sudden incapacitation, while chronic anemia may present a more subtle risk for incapacitation. [aopa.org]

The barium and air create an outline around your colon, allowing the doctor to see if abnormalities are present. Other tests. [secondopinion-tv.org]

During the physical exam, your doctor will press on your abdomen to see if there is any discomfort or masses present. [verywell.com]

• Weight Loss

  Symptoms of colon cancer may include persistent constipation or diarrhea, blood in the stool, and unexplained fatigue or weight loss. [msdmanuals.com]

  loss with no known reason Fatigue Nausea or vomiting Because you may not have symptoms at first, it's important to have screening tests. [medlineplus.gov]

  loss In most cases, people who have these symptoms do not have cancer. [keckmedicine.org]

  loss Constant feeling of fatigue or tiredness Diagnosis Tests used to identify potential colon cancers include: Fecal occult blood test Colonoscopy Sigmoidoscopy Barium enema CT colonography Additional tests may confirm the presence of colon cancer, [cancer.uvahealth.com]

• Fatigue

  Symptoms of colon cancer may include persistent constipation or diarrhea, blood in the stool, and unexplained fatigue or weight loss. [msdmanuals.com]

  Common side effects include: hair loss nausea fatigue vomiting Combination therapies often mix multiple types of chemotherapy or combine chemotherapy with other treatments. [medicalnewstoday.com]

  The symptoms of anemia include weakness, easy fatiguability, shortness of breath and palpitations. These symptoms are explained by the anatomy of ascending colon. [livestrong.com]

• Familial Adenomatous Polyposis

  […] member known to have familial adenomatous polyposis. [nccs.com.sg]

  Scientists have discovered several genes contributing to a susceptibility to two types of colon cancer: FAP (familial adenomatous polyposis) So far, only one gene has been discovered that leads to FAP: the APC gene, located on human chromosome 5. [genome.gov]

  Adenomatous polyposis syndromes account for about 15 to 20 percent of these tumors, or 1 to 2 percent of all colon cancers. 6 FAMILIAL ADENOMATOUS POLYPOSIS SYNDROMES Familial adenomatous polyposis is an autosomal dominant syndrome in which hundreds to [aafp.org]

  Other factors that may increase your chance of colon cancer include: Hereditary conditions such as familial adenomatous polyposis Personal history of colon or rectal cancer, or polyps Family history of colon or rectal cancer, especially a parent, sibling [cancer.uvahealth.com]

  Several inherited conditions also increase the risk of colon cancer, including: attenuated familial adenomatous polyposis familial adenomatous polyposis (FAP) Gardner syndrome, which is a different type of FAP Lynch syndrome, or hereditary nonpolyposis [medicalnewstoday.com]

• Swelling

  Swelling around the hand and wrist. Although arthralgias are more common in HSP, arthritis can occur as well as periarticular swelling, such as the tenosynovitis shown here. Figure 6. Swelling around the ankle and foot. Figure 7. [hopkinsvasculitis.org]

  Take your child back to the GP if they have HSP and they have increasing pain or swelling, blood in their stools or urine, or if you are worried at all. [rch.org.au]

  Symptoms of Henoch-Schonlein Purpura The classic symptoms of HSP are rash, joint pain and swelling, abdominal pain, and/or related kidney disease, including blood in urine. [webmd.com]

  Physical exam to check for tenderness, swelling, and/or unusual growths. [mycoloncancercoach.org]

  People with Henoch-Schonlein purpura often have pain and swelling around the joints — mainly in the knees and ankles. Joint pain sometimes precedes the classical rash by one or two weeks. [mayoclinic.org]

• Asymptomatic

  Non-resection versus resection for an asymptomatic primary tumour in patients with unresectable Stage IV colorectal cancer. Cochrane Database of Systematic Reviews 2012, Issue 8. Art. No.: CD008997. DOI: 10.1002/14651858.CD008997.pub2 [cochrane.org]

  Commencing invasive screening and polypectomies in asymptomatic people at age 50 is just as absurd as taking contraceptives after menopause. Rectal Exam: A gloved and lubricated finger is inserted to check for lumps. [thetruthaboutcancer.com]

  This malignancy has a significant incidence, is life-threatening and has a long asymptomatic period during which it can be diagnosed in an early stage that is amenable to treatment. A number of colorectal screening tests are available. [aafp.org]

  The prognosis tends to be worse in symptomatic as compared to asymptomatic individuals. The most common presenting symptom of colorectal cancer is rectal bleeding. [patients.gi.org]

  Screening for colorectal cancer The term "screening" is properly applied only to the use of testing to look for evidence of cancer or pre-cancerous polyps in individuals who are asymptomatic and at only average risk for a type of cancer. [medicinenet.com]

• Constipation

  People may experience some chronic pain and anemia along with intermittent constipation. [livestrong.com]

  They’re more likely to occur during pregnancy, aging, sitting for long periods of time, chronic constipation or diarrhea, straining or lifting heavy objects. [keckmedicine.org]

  Symptoms of colon cancer may include persistent constipation or diarrhea, blood in the stool, and unexplained fatigue or weight loss. [msdmanuals.com]

  Hemorrhoids can also be caused by: Pregnancy Aging Sitting for long periods of time Chronic constipation or diarrhea Straining Lifiting objects that are too heavy Symptoms of Hemorrhoids Although the most common symptom of hemorrhoids is blood in the [stopcoloncancernow.com]

• Vomiting

  Often, people with left-sided cancers present to the emergency room with a quartet of symptoms--abdominal pain, abdominal distention, vomiting and constipation. These are symptoms of bowel obstruction, a surgical emergency. [livestrong.com]

  A feeling that your bowel does not empty completely Blood (either bright red or very dark) in your stool Stools that are narrower than usual Frequent gas pains or cramps, or feeling full or bloated Weight loss with no known reason Fatigue Nausea or vomiting [medlineplus.gov]

  Common side effects include: hair loss nausea fatigue vomiting Combination therapies often mix multiple types of chemotherapy or combine chemotherapy with other treatments. [medicalnewstoday.com]

  Often, a person has nausea and/or vomiting and a loss of appetite. Diverticulitis Diverticulitis refers to inflammation of colon diverticulum (a pouch located in the colon wall). [verywell.com]

  Abdominal or pelvic pain or bloating Unexplained weight loss Vomiting If you experience any of these signs or symptoms, it is important to see your doctor for evaluation. [my.clevelandclinic.org]

• Nausea

  Treatment also kills other rapidly dividing cells such as blood cells, and cells of the hair root and digestive tract, resulting in commonly known side effects like hair loss and nausea. Radiation. [innerbody.com]

  […] constipation A feeling that your bowel does not empty completely Blood (either bright red or very dark) in your stool Stools that are narrower than usual Frequent gas pains or cramps, or feeling full or bloated Weight loss with no known reason Fatigue Nausea [medlineplus.gov]

  Gut problems such as nausea, vomiting, diarrhea, or stomach pain. Kidney problems, particularly protein or blood in the urine. Excessive tiredness. [medicalnewstoday.com]

  Try ginger if nausea is a problem because of chemotherapy. A cup of ginger tea or the powdered herb (100 to 200 mg) every four hours may quell symptoms. Take it with food to avoid stomach irritation. [besthealthmag.ca]

• Rectal Pain

  Later stages of bowel cancer include: Blood in stools Constipation or diarrhoea that continues for more than 6 weeks Stomach or rectal pain Unexplained weight loss Bleeding in the bowel can cause anaemia, which in turn can lead to persistent tiredness [diabetes.co.uk]

  Bowel cancer symptoms Symptoms of bowel cancer include: change in bowel habit with diarrhoea, constipation or the feeling of incomplete emptying thin bowel movements blood in the stools abdominal pain, bloating or cramping anal or rectal pain a lump in [cancer.org.au]

  This test, called a digital rectal exam, is a quick screen to make sure that any bleeding is actually coming from your rectum. This is not painful, but it is mildly uncomfortable for some people. It takes only a few seconds. [emedicinehealth.com]

• Hematochezia

  Hematochezia as the presenting symptom tends to be associated with tumors located in the descending colon. [aafp.org]

• Ulcer

  Ulcerative colitis and colorectal cancer Chronic ulcerative colitis causes inflammation of the inner lining of the colon. Colon cancer is a recognized complication of chronic ulcerative colitis. [medicinenet.com]

  Inflammatory polyps are usually found in people with an inflammatory bowel disease (IBD) such as ulcerative colitis. Hyperplastic and inflammatory polyps are usually found during a colonoscopy or sigmoidoscopy. [cancer.ca]

  These include ulcerative colitis, which is a break in the lining of the colon, and Crohn’s disease, which is inflammation of the gastrointestinal tract. Both ulcerative colitis and Crohn’s are types of inflammatory bowel disease (IBD). Lifestyle. [innerbody.com]

  Taking aspirin daily has some risks, including gastrointestinal bleeding and ulcers. These options are generally reserved for people with a high risk of colon cancer. [mayoclinic.org]

  In rare circumstances such as in longstanding ulcerative colitis or in cases where large numbers of polyps are found, then the entire colon may need to be removed. [emedicinehealth.com]

• Irritability

  Depending in your toilet habits, you can exacerbate irritation and cause more bleeding and itching. Excessive rubbing or cleaning of the affected area can just make it worse. [stopcoloncancernow.com]

  Across our AdventHealth network of care, we specialize in helping people like you learn to manage and overcome gastrointestinal disorders ranging from irritable bowel syndrome and diverticulosis to Crohn's disease and gastrointestinal cancers. [floridahospital.com]

  Here are some of the most common signs and symptoms of hemorrhoids: Itching or irritation in the anal area Bright red blood on toilet tissue, stool or in the toilet bowl Pain or discomfort, especially during bowel movements A sensitive or painful lump [keckmedicine.org]

  Irritable Bowel Syndrome Abdominal spasms and cramping are common in irritable bowel syndrome but are generally eased with defecation. [verywell.com]

  Henoch-Schönlein purpura (hee-nok shon-line per-per-a), or HSP, is a condition where blood vessels become inflamed (irritated and swollen). HSP usually affects the small blood vessels in the skin, causing a rash that is called purpura. [rch.org.au]

• Confusion

  Fissures are quite common in the general population, but are often confused with other causes ... Anal warts (condyloma acuminata) are caused by the human papilloma virus (HPV), the most common sexually transmitted disease (STD). [fascrs.org]

  Perhaps this is true of most cooks, when as Ruth says she is confused, lonely or frightened she heads into the kitchen to cook. [oracibo.com]

Your doctor will require a staging workup, including colonoscopy, CEA blood level, chest X-ray, and CT scan of the abdomen and pelvis, to determine if the cancer has spread. [mycoloncancercoach.org]

You may be referred to an enterostomal therapist (a health care professional, often a nurse, trained to help people with their colostomies) as part of your initial workup. [healthywomen.org]

[…] structures (T4) N0 M0 Stage IIA T3 N0 M0 Stage IIB T4a N0 M0 Stage IIC T4b N0 M0 Stage IIIA T1-2 T1 N1/N1c N2a M0 Stage IIIB T3-4a T2-3 T1-2 N1/N1c N2a N2b M0 Stage IIIC T4a T3-4a T4b N2a N2b N1-2 M0 Stage IVA T1-4 N1-3 M1a Stage IVB T1-4 N1-3 M1b See Workup [emedicine.medscape.com]

• Colitis

  Ulcerative colitis and colorectal cancer Chronic ulcerative colitis causes inflammation of the inner lining of the colon. Colon cancer is a recognized complication of chronic ulcerative colitis. [medicinenet.com]

  Colon cancer also can develop from other conditions, such as colitis. What is Colon Polyp? A polyp is a growth that occurs in the colon and other organs. [starpoli.com]

  Inflammatory polyps are usually found in people with an inflammatory bowel disease (IBD) such as ulcerative colitis. Hyperplastic and inflammatory polyps are usually found during a colonoscopy or sigmoidoscopy. [cancer.ca]

  Also at high risk for developing colon cancers are people with any of the following: Ulcerative colitis or Crohn's colitis ( Crohn's disease ) Breast, uterine, or ovarian cancer now or in the past A family history of colon cancer The risk of colon cancer [emedicinehealth.com]

  These include ulcerative colitis, which is a break in the lining of the colon, and Crohn’s disease, which is inflammation of the gastrointestinal tract. Both ulcerative colitis and Crohn’s are types of inflammatory bowel disease (IBD). Lifestyle. [innerbody.com]

Chemotherapy may also be used after surgery (called adjuvant treatment). Most adjuvant treatment is given for about 6 months. [cancer.org]

Any questions you may have about colorectal cancer, treatments or clinical trials can be answered by your doctor. [bswhealth.com]

Radiotherapy can be used as a standalone treatment to shrink a tumor or destroy cancer cells, or alongside other cancer treatments. Radiation treatments are not often used until a later stage. [medicalnewstoday.com]

Treatment Options for Colon Cancer For information about the treatments listed below, see the Treatment Option Overview section. [cancer.gov]

However, treatment can often slow down the progression of the cancer. The treatment of cancer is a developing area of medicine. New treatments continue to be developed and the information on outlook above is very general. [patient.info]

These have a worse prognosis than non-mucinous carsinomas. Photomicrograph of a primary mucinous adenocarcinoma. Click to enlarge. [oncolex.org]

For the current study, the researchers sought to confirm a link between tumor location and prognosis in metastatic colon cancer (mCRC). They used data from three separate studies which included a total of 2,027 patients. [medicaldaily.com]

Prognosis Gastrointestinal or pulmonary bleeding can be life-threatening. The long term prognosis depends on the extent of the renal involvement. [orpha.net]

Prognosis of Colorectal Cancer A prognosis is the probable outcome of an illness based upon all the relevant facts of the case. [nccs.com.sg]

Etiology SHP is associated with deposition of IgA-dominant immune complexes in arterioles, capillaries, and venules, but the exact etiology remains unknown. [orpha.net]

It is a multifactorial disease process, with etiology encompassing genetic factors, environmental exposures (including diet), and inflammatory conditions of the digestive tract. [emedicine.medscape.com]

Related Journals: American Journal of Epidemiology, Journal of Clinical Epidemiology, Cancer Epidemiology Biomarkers and Prevention, International Journal of Epidemiology, Epidemiology, Journal of Immunology, Annual Review of Immunology, Journal of Allergy [colorectal-cancer.imedpub.com]

Summary Epidemiology SHP usually affects children and is rare in adults. Annual incidence in children is estimated at between 1/6,660 and 1/4,880, whereas it is estimated at around 1/1,000,000 in adults. The male-to-female ratio is 1.5:1. [orpha.net]

Poster No. 253 COMPA Page 95 and 96: Poster No. 265 Poster No. 266 Poste Page 97 and 98: Poster No. 280 ORGAN-SPECIFIC AUTOA Page 99 and 100: Poster Viewing Three Friday 01 May Page 101 and 102: Poster No. 303 Poster No. 304 Poste Page 103 and 104: Epidemiology [yumpu.com]

The mortality data came from the National Cancer Institute's Surveillance, Epidemiology and End Results Program, as reported by the National Center for Health Statistics, which tracks cause-specific mortality rates. [edition.cnn.com]

However, most of these studies were retrospective epidemiologic studies and have yet to be validated in prospective, placebo-controlled, interventional trials. [emedicine.medscape.com]

Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 126. National Cancer Institute website. [medlineplus.gov]

Sleisinger & Fordtran's Gastrointestinal and liver disease; pathophysiology, diagnosis, management. 6th ed. Philadelphia: Saunders, 1998. 11. Launoy G, Smith TC, Duffy SW, Bouvier V. [aafp.org]

Pathophysiology Genetically, colorectal cancer represents a complex disease, and genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma. [emedicine.medscape.com]

The procedure takes 15 - 30 minutes during which time the patient is sedated to prevent discomfort. [coloncancerfoundation.org]

"Screening for Colorectal Cancer" in Guide to Clinical Preventative Services, 2nd Edition, Report of the U.S. Preventative Services Task Force, U.S. [labtestsonline.it]

Eating a rainbow of plant antioxidants is another strategy to prevent colon cancer. [thetruthaboutcancer.com]

Colorectal Cancer Prevention: Diet Eating a nutritious diet, getting enough exercise, and controlling body fat could prevent 45% of colorectal cancers, according to researchers. [onhealth.com]