Presentation
We present four cases and a brief review of the literature to highlight HSP in the differential diagnosis of patients who present with any of the typical clinical signs and symptoms. [ncbi.nlm.nih.gov]
The mortality rate in patients who present with hematochezia is only 19 percent, compared with 83 percent in patients with any other presenting symptom. [aafp.org]
These terms mean that cancer is present in the vessels (arteries, veins, and/or lymphatics) of the colon and that there is an increased chance that cancer could spread out of the colon. [adasp.org]
These can present even as young as 10 years' of age. [netdoctor.co.uk]
Entire Body System
- Fatigue
Symptoms of colon cancer may include persistent constipation or diarrhea, blood in the stool, and unexplained fatigue or weight loss. [msdmanuals.com]
Diarrhea or constipation A feeling that your bowel does not empty completely Blood (either bright red or very dark) in your stool Stools that are narrower than usual Frequent gas pains or cramps, or feeling full or bloated Weight loss with no known reason Fatigue [medlineplus.gov]
Common side effects include: hair loss nausea fatigue vomiting Combination therapies often mix multiple types of chemotherapy or combine chemotherapy with other treatments. [medicalnewstoday.com]
The symptoms of anemia include weakness, easy fatiguability, shortness of breath and palpitations. These symptoms are explained by the anatomy of ascending colon. [livestrong.com]
Gastrointestinal
- Hematochezia
Hematochezia as the presenting symptom tends to be associated with tumors located in the descending colon. [aafp.org]
- Lower Abdominal Pain
[…] liver, abdominal bloating, pain in lower back or bladder symptoms such as urinary frequency or blood in the urine. [bccancer.bc.ca]
Workup
Your doctor will require a staging workup, including colonoscopy, CEA blood level, chest X-ray, and CT scan of the abdomen and pelvis, to determine if the cancer has spread. [mycoloncancercoach.org]
You may be referred to an enterostomal therapist (a health care professional, often a nurse, trained to help people with their colostomies) as part of your initial workup. [healthywomen.org]
[…] structures (T4) N0 M0 Stage IIA T3 N0 M0 Stage IIB T4a N0 M0 Stage IIC T4b N0 M0 Stage IIIA T1-2 T1 N1/N1c N2a M0 Stage IIIB T3-4a T2-3 T1-2 N1/N1c N2a N2b M0 Stage IIIC T4a T3-4a T4b N2a N2b N1-2 M0 Stage IVA T1-4 N1-3 M1a Stage IVB T1-4 N1-3 M1b See Workup [emedicine.medscape.com]
Treatment
English Ecansya is indicated for the treatment of: for the adjuvant treatment of patients following surgery of stage III (Dukes’ stage C) colon cancer (see section 5.1). [mymemory.translated.net]
The treatment you get for your colorectal cancer may depend on the “stage” of the disease. For all except stage IV, you’ll first get surgery to remove the tumor. You may also get other treatments. [webmd.com]
Chemotherapy may also be used after surgery (called adjuvant treatment). Most adjuvant treatment is given for about 6 months. [cancer.org]
When treatment is necessary, it is not due to the rash itself. Treatment is needed for causes such as leukemia, or effects including kidney failure. [medicalnewstoday.com]
Any questions you may have about colorectal cancer, treatments or clinical trials can be answered by your doctor. [bswhealth.com]
Prognosis
Prognosis Gastrointestinal or pulmonary bleeding can be life-threatening. The long term prognosis depends on the extent of the renal involvement. [orpha.net]
These have a worse prognosis than non-mucinous carsinomas. Photomicrograph of a primary mucinous adenocarcinoma. Click to enlarge. [oncolex.org]
For the current study, the researchers sought to confirm a link between tumor location and prognosis in metastatic colon cancer (mCRC). They used data from three separate studies which included a total of 2,027 patients. [medicaldaily.com]
The overall prognosis in HSP is excellent, but the long-term morbidity depends on the renal and neurologic involvement. [ncbi.nlm.nih.gov]
Etiology
Etiology SHP is associated with deposition of IgA-dominant immune complexes in arterioles, capillaries, and venules, but the exact etiology remains unknown. [orpha.net]
It is a multifactorial disease process, with etiology encompassing genetic factors, environmental exposures (including diet), and inflammatory conditions of the digestive tract. [emedicine.medscape.com]
Epidemiology
Related Journals: American Journal of Epidemiology, Journal of Clinical Epidemiology, Cancer Epidemiology Biomarkers and Prevention, International Journal of Epidemiology, Epidemiology, Journal of Immunology, Annual Review of Immunology, Journal of Allergy [colorectal-cancer.imedpub.com]
缅甸边境地区一起恶性疟暴发疫情调查分析 1 孟连县疾病预防控制中心, 云南 孟连 665800; 2 英国无国界世界卫生组织驻缅甸第二特区办事处; 3 云南省虫媒传染病防控研究重点实验室(筹建), 云南省寄生虫病防治所, 云南 普洱 665000 Epidemiological analysis of an outbreak of Plasmodium falciparum in the border areas of Myanmar YU Ai-shui1, YANG Yong-hui1, LI [bmsw.net.cn]
Summary Epidemiology SHP usually affects children and is rare in adults. Annual incidence in children is estimated at between 1/6,660 and 1/4,880, whereas it is estimated at around 1/1,000,000 in adults. The male-to-female ratio is 1.5:1. [orpha.net]
Poster No. 253 COMPA Page 95 and 96: Poster No. 265 Poster No. 266 Poste Page 97 and 98: Poster No. 280 ORGAN-SPECIFIC AUTOA Page 99 and 100: Poster Viewing Three Friday 01 May Page 101 and 102: Poster No. 303 Poster No. 304 Poste Page 103 and 104: Epidemiology [yumpu.com]
The mortality data came from the National Cancer Institute's Surveillance, Epidemiology and End Results Program, as reported by the National Center for Health Statistics, which tracks cause-specific mortality rates. [edition.cnn.com]
Pathophysiology
Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 126. National Cancer Institute website. [medlineplus.gov]
Sleisinger & Fordtran's Gastrointestinal and liver disease; pathophysiology, diagnosis, management. 6th ed. Philadelphia: Saunders, 1998. 11. Launoy G, Smith TC, Duffy SW, Bouvier V. [aafp.org]
Pathophysiology Genetically, colorectal cancer represents a complex disease, and genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma. [emedicine.medscape.com]
Prevention
[…] and early detection of cervical cancer: American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer. [nccn.org]
We need everybody to join us in the effort because that's how we can make the advances that will allow us to do a better job of preventing what is truly a preventable disease, at least, in large part. [news-medical.net]
Visit our Cancer Nutrition Services Program for recipes and nutrition recommendations to prevent or reduce your risk of cancer. Kale contains special cancer preventing properties. Learn more » [stanfordhealthcare.org]
The procedure takes 15 - 30 minutes during which time the patient is sedated to prevent discomfort. [coloncancerfoundation.org]
"Screening for Colorectal Cancer" in Guide to Clinical Preventative Services, 2nd Edition, Report of the U.S. Preventative Services Task Force, U.S. [labtestsonline.org]