Presentation
[…] on Admission - Yes) Total Medicare Hospitalizations - Oct 2015 to Sep 2018 (Present on Admission - Yes) Total National Projected Hospitalizations - Annualized (Present on Admission - Not Y) Total Medicare Hospitalizations - Oct 2015 to Sep 2018 (Present [dexur.com]
All endodermal sinus tumors presented AFP elevation at diagnosis. In patients with mixed tumors, three presented high AFP and β-HCG, one presented high AFP, and two presented high β-HCG. [scielo.br]
It is an unpredictable entity due to its atypical metastatic profile at presentation. [jcmtjournal.com]
Case Presentation This 22-year-old man of European descent presented with unspecific scrotal discomfort lasting for two weeks. Clinical history is uneventful. The patient is unmarried and has no children so far. [hindawi.com]
In contrast, traumatic injury, epididymo-orchitis and testicular torsion present with significant pain. [cancertherapyadvisor.com]
Entire Body System
- Pain
Lower back pain, shortness of breath, chest pain, and bloody sputum or phlegm can be symptoms of later-stage testicular cancer. Swelling of 1 or both legs or shortness of breath from a blood clot can be symptoms of testicular cancer. [cancer.net]
I was still working at the time and the pain and that was just horrendous, I was just sort of total pain. I used to come home, sit in bed, go to bed and just sort of sit upright because I couldn't lie down with the pain. [healthtalk.org]
[…] fatigue, fever, sweating, coughing, shortness of breath or mild chest pains Headache and confusion In boys, testicular cancer can also cause early signs of puberty, such as accelerated voice deepening and the growth of facial and body hair. [moffitt.org]
Orchitis is a painful swelling of one or both testicles. It is caused by a bacterial or viral infection. Orchitis is most common in boys after puberty. It is usually treated with antibiotics. [cancer.ca]
Case Presentation A 44-year- old male patient presented to the emergency department with right and left lower quadrant pain. It was learnt that he had dysuria along with consistent pain. [clinicsinsurgery.com]
- Swelling
Stand in front of the mirror and look for any swelling on the skin of the scrotum. Feel the size and weight of the testicles first. With fingers and thumbs press around and be receptive to any lumps or unusual swellings. [medicalnewstoday.com]
Swelling of 1 or both legs or shortness of breath from a blood clot can be symptoms of testicular cancer. A blood clot in a large vein is called deep venous thrombosis or DVT. [cancer.net]
Consult a doctor if you have any of these symptoms: Swelling in the scrotum A lump or swelling in either testicle Build-up of fluid on the scrotum Dull ache in the groin or lower abdomen Pain or discomfort in the scrotum or a testicle Cleveland Clinic [my.clevelandclinic.org]
Lumps, swellings and asymmetry are not always due to cancer, but it is sensible to have any lump or swelling examined by a doctor. Here men we interviewed describe how they found a lump while taking a bath or a shower. [healthtalk.org]
Most swellings and lumps in the scrotum are not due to cancer. There are various other causes. However, you should always tell a doctor if you discover a swelling or lump in one of your testicles (testes). It needs checking out as soon as possible. [patient.info]
- Infertility
Infertility: Men who are infertile have a higher likelihood of developing testicular cancer. [my.clevelandclinic.org]
Other side effects, like infertility, are possible. If the tumor is malignant, and the man has a normal testicle on the other side, then TSS is not recommended. [urologyhealth.org]
Treatments may also cause infertility. If you may want children later on, you should consider sperm banking before treatment. NIH: National Cancer Institute [medlineplus.gov]
If you’re diagnosed with testicular cancer, you’re more likely to have lower fertility, or complete infertility, even before any treatment starts. [andrologyaustralia.org]
- Pathologist
A pathologist is a specially trained doctor who identifies cancerous cells and tumors. DF/BWCC pathologists are well-known for their expert evaluation of testicular cancer. They will diagnose and classify your cancer quickly and competently. [dana-farber.org]
Germinal cell tumors Due to the frequent appearance of several tumor type components in germinal tumors of the testis, the pathologist must study several microscopic sections. [oncolex.org]
A pathologist examines the biopsy under a microscope. [dovemed.com]
Panel composition The European Association of Urology (EAU) Guidelines Panel on Testicular Cancer consists of a multidisciplinary group of clinicians including, urologists, oncologists, radiotherapists and a pathologist. [uroweb.org]
Condition of the specimen—fresh, in formalin, intact, incised by surgeon or pathologist, etc. C. Identification—patient name, case number, laterality, specimen identification (“labelled as … ”) D. [nature.com]
- Falling
GOING WITHOUT THE FLOW The Moment The Niagara Falls Ran Dry in 1969, In Photos In June 1969, the US Army Corps of Engineers turned off American Falls, one of three waterfalls that makes up Niagara Falls. [digg.com]
There was history of blunt trauma during a fall. It was hard, proximal to the left testis of 5X5 cm in size, non fluctuant, and non transilluminant. The overlying skin was free. A diagnosis of chronic haematocele was made. [ispub.com]
Traumatic fracture is caused by excessive force on an otherwise normal bone, such as falling from heights, traffic accidents, gunshots, sport injuries or even traumatic birth. Pathological fracture describes fracture in abnormal or weakened bones. [limblength.org]
The stages are called Stage I, II or III (1, 2 or 3) and then letters indicate where in the stage the cancer falls, for example stage IIa is somewhat less severe that stage IIb. [testicularcancersociety.org]
Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet 1993;341(8857):1392–5. Walcott FL, Hauptmann M, Duphorne CM, Pillow PC, Strom SS, Sigurdson AJ. [hellenicurology.com]
Gastrointestinal
- Nausea
Radiation therapy may cause the following temporary side effects: tiredness rashes muscle stiffness joint stiffness loss of appetite nausea Chemotherapy Chemotherapy is the use of chemicals (medication) to destroy cancer cells. [medicalnewstoday.com]
Other differences in women with nausea such as dietary preferences may also exist.47 At this time, no definitive conclusions can be drawn about the association of nausea in pregnancy and testicular cancer. [onlinelibrary.wiley.com]
Alternative Nonpharmacologic Management of Nausea and Vomiting. National Cancer Institute, États-Unis. [Consulté le 15 août 2005]. www.nci.nih.gov 5. Gruzelier JH. [passeportsante.net]
Advanced symptoms include: neck mass; coughing or trouble breathing; stomach problems such as nausea, vomiting, bleeding or anorexia; lower back pain; bone pain; nerve pain or leg swelling. [testicularcancersociety.org]
Other potential side effects include nausea, diarrhea and fatigue. A special device can be used to protect the unaffected testicle to preserve fertility. Chemotherapy refers to the use of drugs in treating cancer. [medical-dictionary.thefreedictionary.com]
- Vomiting
Alternative Nonpharmacologic Management of Nausea and Vomiting. National Cancer Institute, États-Unis. [Consulté le 15 août 2005]. www.nci.nih.gov 5. Gruzelier JH. [passeportsante.net]
As a result, they may cause various problems, including hair loss, lowered resistance to infection, loss of appetite, nausea and vomiting, and mouth sores. [tcrc.acor.org]
As chemotherapy attacks healthy cells as well as cancerous ones, the patient may experience the following temporary side effects: nausea vomiting hair loss mouth sores tiredness malaise Most people immediately link chemotherapy with uncomfortable side [medicalnewstoday.com]
Advanced symptoms include: neck mass; coughing or trouble breathing; stomach problems such as nausea, vomiting, bleeding or anorexia; lower back pain; bone pain; nerve pain or leg swelling. [testicularcancersociety.org]
For example, meditation and relaxation exercises may prove effective in reducing nausea and vomiting. Some dietary modifications and nutritional supplements may be helpful in assisting with recovery after surgery. [medical-dictionary.thefreedictionary.com]
Musculoskeletal
- Back Pain
Lower back pain, shortness of breath, chest pain, and bloody sputum or phlegm can be symptoms of later-stage testicular cancer. Swelling of 1 or both legs or shortness of breath from a blood clot can be symptoms of testicular cancer. [cancer.net]
[…] or discomfort in a testicle or the scrotum Enlargement or tenderness of the breasts Back pain Cancer usually affects only one testicle. [mayoclinic.org]
Less common symptoms include: feeling of heaviness in the scrotum swelling or lump in the testicle change in the size or shape of the testicle feeling of unevenness pain or ache in the lower abdomen, the testicle or scrotum back pain enlargement or tenderness [cancer.org.au]
- Low Back Pain
The earliest sign of testicular cancer is a small, hard, painless lump that cannot be separated from the testicle; it is occasionally accompanied by low back pain. Men often describe a feeling of “heaviness” or “dragging” in the testicles. [medical-dictionary.thefreedictionary.com]
Skin
- Night Sweats
In 25-41% of patients the disease presentation is with fever, night sweats, and weight loss but are more frequent in the advanced stage 39, 40, 41. The involvement of retroperitoneal lymph nodes often leads to pain and ascites 42. [wcrj.net]
Urogenital
- Cryptorchidism
Cryptorchidism is best corrected surgically in childhood. Correcting cryptorchidism decreases the risk of testicular cancer. However, even if cryptorchidism is corrected, the risk of cancer is still higher than for men who never had cryptorchidism. [merckmanuals.com]
Characteristics of the Cohort of Men Who Underwent Surgery for Cryptorchidism. [nejm.org]
Cryptorchidism Clinical Pediatric Urology Third Edition. Philadelphia, Saunders. 1992;2:1050-83. Swerdlow AJ, Higgins CD, Pike MC. Risk of testicular cancer in cohort of boys with cryptorchidism. BMJ. 1997;314(7093):1507-11. [clinicsinsurgery.com]
[…] risk is greatest in cases of bilateral cryptorchidism. [aafp.org]
- Testicular Mass
Conclusion Currently, no typical ultrasound features can definitively distinguish intratesticular adenomatoid tumors from malignant testicular masses. [eurjmedres.biomedcentral.com]
Seminomas commonly metastasize through the lymphatic system and patients might present with signs of disseminated disease rather than a testicular mass. [lecturio.com]
Biopsy finding On gross examination: right testicular mass of 13 cm × 8 cm × 6 cm with cut surface showing a solid variegated appearance. Left testicular mass of 10 cm × 8 cm × 6 cm with cut surface showing a solid variegated appearance. [jcmtjournal.com]
Larger masses may develop a more heterogeneous appearance as a result of hemorrhage and necrosis. Leukemia, lymphoma, and metastases may also present as testicular masses. [sonoworld.com]
- Scrotal Mass
History Part 3: Competing diagnoses that can mimic scrotal/testicular nodules or masses. A focal scrotal abscess can feel like a scrotal mass. [cancertherapyadvisor.com]
A scrotal mass is an abnormal bulge or lump inside your scrotum. The scrotum is a sac of skin that contains your testicles. A scrotal mass can be a swollen testicle or it can contain fluid or other tissue. [healthline.com]
Many patients discover the mass themselves after minor scrotal trauma. [msdmanuals.com]
[…] from other scrotal masses, including testicular germ cell tumors. [ncbi.nlm.nih.gov]
- Painless Testicular Mass
We report a case of 52-year-old male patient with a history of human immunodeficiency virus who presented with a painless, testicular mass for 2 months. [ncbi.nlm.nih.gov]
However, ITGCN does not appear to occur in testes harboring prepubertal yolk sac tumors. [8] A painless testicular mass is the most common finding in a child with a testicular tumor. [indianjcancer.com]
Most of the patients with AGCT presented with slowly growing painless testicular masses with several of whom reporting a duration of symptoms for many years [7, 22, 30]. [hindawi.com]
Most common germ cell tumor Mean age is 40 yrs Very rare in children Patients present with painless testicular mass 30 % have metastases at presentation, but only 3% have symptoms related to metastases. 11. [slideshare.net]
A painless testicular mass is the classic presentation for testicular cancer, although a number of patients present with diffuse pain or swelling. Ultrasonography may be helpful in confirming the presence of a scrotal mass within the testicle. [aafp.org]
- Scrotal Pain
The main manifestations were testicular tumor and scrotal pain. [scielo.br]
Indications include the following [10] : Evaluation of scrotal pain, including but not limited to testicular trauma, ischemia/torsion, and infectious or inflammatory scrotal disease. [emedicine.medscape.com]
Figure 10a Figure 10b Testicular hematoma mimicking a tumor in a 36-year-old man who presented with right scrotal pain after being injured during a soccer game. [pubs.rsna.org]
Here we report the case of a 22-year-old male who presented with unspecific scrotal symptoms. Scrotal sonography disclosed a 6 mm hypoechoic intratesticular lesion. [hindawi.com]
Workup
Review Topic QID: 106375 5 No further workup, instruct patient to return if symptomatic M1 Select Answer to see Preferred Response PREFERRED RESPONSE 2 Sorry, this question is for PEAK Premium Subscribers only ARTICLES (4) VIDEOS (1) Topic COMMENTS (12 [medbullets.com]
Metastatic workup was done: contrast-enhanced computed tomography of whole abdomen and pelvis was within normal limits. [jcmtjournal.com]
Laboratory workup disclosed no abnormal results. [hindawi.com]
These patients should undergo a full course of antibiotics and if the swelling is not resolved after that, they should undergo further workup to exclude possible testicular tumor. [lecturio.com]
Treatment
Treatment options include: Surveillance Surgery Radiation Chemotherapy Before any treatment starts, men should talk with their urologist about if they want to have a child. [urologyhealth.org]
[…] or come back Men who are going to get radiation or chemotherapy may store their sperm before treatment, because these treatments may cause fertility problems. [merckmanuals.com]
Sometimes fertility can be interrupted by the treatments for both types of testicular germ cell tumours. For more information on fertility and cancer treatment visit our fertility info for men page. [canteen.org.au]
The main treatment options for testicular cancer are surgery, radiotherapy, and chemotherapy; the treatment of choice depends on the tumour type, risk scoring, and prognosis. [teachmesurgery.com]
Prognosis
Cases with intermediate prognosis should be treated with cycles of chemotherapy, whilst those with poor prognosis should be treated with one cycle of chemotherapy before reassessment (those with marker decline should have continued chemotherapy cycles [teachmesurgery.com]
Prognosis for testicular cancer Prognosis means the expected outcome of a disease. An individual's prognosis depends on the type and stage of cancer as well as their age and general health at the time of diagnosis. [cancer.org.au]
Prognosis of Testicular Cancer Prognosis is ranked good, intermediate or poor for non-seminoma tumors on some parameters Good prognosis is seen in: Primary testicular or retroperitoneal lesion No nonpulmonary visceral metastases low level of tumor markers [lecturio.com]
NSGCT: Patients with good-prognosis metastatic NSGCT should receive three cycles of BEP chemotherapy. [patient.info]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Urinalysis, urine culture and complete blood count help to differentiate infectious etiologies from non-infectious etiologies. Furthermore, in the case of infectious etiologies, urine culture results guide antimicrobrial selection. [cancertherapyadvisor.com]
ICD-10-CM Codes › C00-D49 Neoplasms › C60-C63 Malignant neoplasms of male genital organs › Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]
The publications considered in this overview are reliable scientific articles on the etiology of testicular cancer from different parts of the world. [onlinelibrary.wiley.com]
The etiology of IMT is not well-defined, but it is most accepted as a reparative process in response to trauma, chronic irritation, or infection. [ncbi.nlm.nih.gov]
Epidemiology
Testicular cancer Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Testicular cancer from other Diseases Epidemiology and Demographics Risk Factors Screening Natural History, [wikidoc.org]
Epidemiology 1996 ;7: 14 - 19 20. Swerdlow AJ, Higgins CD, Pike MC. Risk of testicular cancer in cohort of boys with cryptorchidism. BMJ 1997 ;314: 1507 - 1511 [Erratum, BMJ 1997;315:1129.] 21. [nejm.org]
This data briefing examines the epidemiology of the main types of testicular tumours, and considers the likely impact of such a change in coding. [ncin.org.uk]
Testicular tumors are rare and correspond to 1-2% of solid pediatric tumors in males.5 According to the Surveillance, Epidemiology, and End Results (SEER) program, from the U.S. [scielo.br]
Statistics adapted from the American Cancer Society's (ACS) publications, Cancer Facts & Figures 2017 and Cancer Facts & Figures 2020, the ACS website, and the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program (all [cancer.net]
Pathophysiology
Testicular cancer Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Testicular cancer from other Diseases Epidemiology and Demographics Risk Factors Screening Natural History, [wikidoc.org]
Pathophysiology of Testicular Cancer The exact cause of testicular cancer is unknown. [lecturio.com]
Pathophysiology The cause of testicular cancer is not known. The characteristic genetic change found is an isochromosome of the short arm of chromosome 12 [i(12p)], which is often seen in sporadic cancers. [emedicine.medscape.com]
Prevention
Secondary Prevention Cost-Effectiveness of Therapy Future or Investigational Therapies Case Studies Case #1 Testicular cancer On the Web Most recent articles Most cited articles Review articles CME Programs Powerpoint slides Images American Roentgen [wikidoc.org]
Prevention There's no way to prevent testicular cancer. Some doctors recommend regular testicle self-examinations to identify testicular cancer at its earliest stage. But not all doctors agree. [mayoclinic.org]
Causes, Risk Factors, and Prevention Learn about the risk factors for testicular cancer and if there are things you can do that might help lower your risk. Early Detection, Diagnosis, and Staging Know the signs and symptoms of testicular cancer. [cancer.org]
Prevention Preventing most cases testicular cancer is not possible, as the causes are largely unknown. Many men who develop testicular cancer do not have any known risk factors. [medicalnewstoday.com]