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Malignant Neoplasm of the Testis


Presentation

  • For tumors in the sex cord-stromal category (with the exception of the juvenile granulosa cell tumor) specify if adverse prognostic features are present or absent.[nature.com]
  • Case presentation A 36-year-old Caucasian man presented to our institution with an acutely developed severe pain in his right testis.[jmedicalcasereports.biomedcentral.com]
  • Leukemia, lymphoma, and metastases may also present as testicular masses.[sonoworld.com]
  • Such bimodal presentation is also not mentioned but it was found on further analysis that probably in the present series it was due to extra-nodal non Hodgkin's lymphoma (NHL).[jpma.org.pk]
  • It must be emphasised that clinical guidelines present the best evidence available to the experts but following guideline recommendations will not necessarily result in the best outcome.[uroweb.org]
Intermittent Claudication
  • claudication intestine intracranial joint joint prosthesis kidney knee laceration lacrimal lower limb lung malignant molar pregnancy multiple muscle Neoplasm nerve newborn nondisplaced nontraumatic obstetrical trauma obstruction organ Osteochondrosis[books.google.com]
Back Pain
  • Lower back pain, shortness of breath, chest pain, and bloody sputum or phlegm can be symptoms of later-stage testicular cancer. Swelling of 1 or both legs or shortness of breath from a blood clot can be symptoms of testicular cancer.[cancer.net]
  • pain Cancer usually affects only one testicle.[mayoclinic.org]
  • Less common symptoms include: feeling of heaviness in the scrotum swelling or lump in the testicle change in the size or shape of the testicle feeling of unevenness pain or ache in the lower abdomen, the testicle or scrotum back pain enlargement or tenderness[cancer.org.au]
  • Advanced symptoms include: neck mass; coughing or trouble breathing; stomach problems such as nausea, vomiting, bleeding or anorexia; lower back pain; bone pain; nerve pain or leg swelling.[testicularcancersociety.org]
Contusion
  • Elsevier ‏ معاينة محدودة - 2018 عبارات ومصطلحات مألوفة abdomen abnormal Abscess abuse acquired acute ankle artery benign Bite bone brain breast cardiac cell cerebral cervical cervix chronic complication NEC condition congenital connective tissue Continued contusion[books.google.com]
Testicular Mass
  • Leukemia, lymphoma, and metastases may also present as testicular masses.[sonoworld.com]
  • Radical orchiectomy is the treatment of choice for all solid testicular masses. A retroperitoneal lymph node dissection is recommended if the tumor is malignant.[path.upmc.edu]
  • On exam, the physician discovers a hard, testicular mass on the right testis. On further questioning, the patient remarks that he first noticed it 6 months ago, but did not think he needed to have it examined since it wasn't painful.[medbullets.com]
  • Gross photograph of seminoma showing a well defined, yellow homogenous testicular mass. High power view showing monotonous tumour cells divided by thin fibrovascular septae (H & E- 400x).[ncbi.nlm.nih.gov]
  • The unusual presentation of gastric adenocarcinoma as a testicular mass: a favorable response to docetaxel and cisplatin plus oral tegafur/uracil and leucovorin. J Chin Med Assoc. 2010;73:88–92.[jmedicalcasereports.biomedcentral.com]
Swelling of the Scrotum
  • Consult a doctor if you have any of these symptoms: Swelling in the scrotum A lump or swelling in either testicle Build-up of fluid on the scrotum Dull ache in the groin or lower abdomen Pain or discomfort in the scrotum or a testicle Cleveland Clinic[my.clevelandclinic.org]
  • Look for swelling in the scrotum or any changes in appearance. Gently feel the scrotal sac to find a testicle. Examine the testicles one at a time.[urologyhealth.org]
  • Consult a doctor if you have any of these symptoms: Swelling in the scrotum Lump or swelling in either testicle Build-up of fluid on the scrotum Dull ache in the groin or lower abdomen Pain or discomfort in the scrotum or a testicle Cleveland Clinic News[my.clevelandclinic.org]
Testicular Disease
  • Other significant testicular disease III. Features considered optional in the final report A. Stage —the data specified should facilitate application of most staging systems.[nature.com]
Enlarged Testis
  • testis with hypervascularity Abdominal para-aortic lymphadenopathy Left testis with a mixed solid - cystic lesion Gross description Multinodular or bilateral disease Gross images Images hosted on other servers : Metastatic prostatic adenocarcinoma Microscopic[pathologyoutlines.com]

Workup

  • Review Topic QID: 106375 5 No further workup, instruct patient to return if symptomatic M1 Select Answer to see Preferred Response PREFERRED RESPONSE 2 Sorry, this question is for PEAK Premium Subscribers only ARTICLES (4) VIDEOS (1) Topic COMMENTS (12[medbullets.com]

Treatment

  • Treatment options include surgery, radiation and/or chemotherapy. Regular exams after treatment are important. Treatments may also cause infertility.[icd10data.com]
  • Sometimes fertility can be interrupted by the treatments for both types of testicular germ cell tumours. For more information on fertility and cancer treatment visit our fertility info for men page.[canteen.org.au]
  • However, apart from treatment burden, there is a lack of data on genetic or molecular factors that can identify testicular cancer survivors at high risk for treatment-related toxicities.[gucasym.org]
  • Treatment team Depending on your treatment, your treatment team may include a number of the following professionals: GP who looks after your general health and coordinates specialist treatment urologist who specialises in the treatment of diseases of[cancer.org.au]
  • Treatment options include surgery, radiation, and/or chemotherapy. Regular exams after treatment are important. Treatments may also cause infertility. If you may want children later on, you should consider sperm banking before treatment.[medlineplus.gov]

Prognosis

  • Seminoma late metastasis and excellent prognosis Embryonal worse prognosis than seminoma Choriocarcinoma worst prognosis in contrast to good prognosis in females metastasizes to lungs Please rate topic.[medbullets.com]
  • Prognosis for testicular cancer Prognosis means the expected outcome of a disease. An individual's prognosis depends on the type and stage of cancer as well as their age and general health at the time of diagnosis.[cancer.org.au]
  • In advanced stages randomized trials have to clarify if there could be a better outcome with adding new agents or with high-dose chemotherapy for patients with "poor prognosis" and adverse features or patients with a chemoresistant relapse.[ncbi.nlm.nih.gov]
  • Introduction It is a highly malignant tumour with poor prognosis. It is generally diagnosed clinically as a solid or cystic swelling. However, confirmation is made only on histological diagnosis.[ispub.com]
  • Strong Initially offer chemotherapy in seminoma stage CS IIB (BEP x 3 or EP x 4, in good prognosis) as an alternative to radiotherapy. Strong BEP bleomycin, etoposide and cisplatin; PEI cisplatin, etoposide and ifosfamide.[uroweb.org]

Etiology

  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • ICD-10-CM Codes › C00-D49 Neoplasms › C60-C63 Malignant neoplasms of male genital organs › Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10data.com]
  • (Etiology) The causes of Intratubular Germ Cell Neoplasia of Testis are mostly unknown.[dovemed.com]

Epidemiology

  • Epidemiology 1996 ;7: 14 - 19 20. Swerdlow AJ, Higgins CD, Pike MC. Risk of testicular cancer in cohort of boys with cryptorchidism. BMJ 1997 ;314: 1507 - 1511 [Erratum, BMJ 1997;315:1129.] 21.[nejm.org]
  • Definition / general Tumors of the testis which neither originate in the testis nor come from direct extension of tumors arising in nontesticular sites Rarely is the first clinical sign of disease Terminology Also called secondary tumors of the testis Epidemiology[pathologyoutlines.com]
  • Basic epidemiological data regarding each case was collected from the request forms. The data was then analysed for the site of involvement, age distribution and histological types of tumours.[jpma.org.pk]
  • Introduction Testicular tumors can be of germ cell or non-germ cell origin germ cell origin are the majority (95%) and are more commonly malignant non-germ cell origin usually benign Epidemiology incidence most common cancer in men between 15-35 years[medbullets.com]
  • Epidemiological and histomorphological spectrum of our study was comparable to most of the countries except for some African and Western countries.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Prevention

  • Prevention There's no way to prevent testicular cancer. Some doctors recommend regular testicle self-examinations to identify testicular cancer at its earliest stage. But not all doctors agree.[mayoclinic.org]
  • Causes, Risk Factors, and Prevention Learn about the risk factors for testicular cancer and if there are things you can do that might help lower your risk. Early Detection, Diagnosis, and Staging Know the signs and symptoms of testicular cancer.[cancer.org]
  • Long-term complications are of utmost importance and have to be recognized early or, ideally, prevented.[gucasym.org]
  • Preventing testicular cancer There are no proven measures to prevent testicular cancer. Source Understanding Testicular Cancer, Cancer Council Australia ? 2018. Last medical review of source booklet: August 2018.[cancer.org.au]
  • Can I prevent testicular cancer? Because we mostly don’t know what causes testicular cancer, there are no particular ways to prevent it.[andrologyaustralia.org]

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