Presentation
Presentation Most testicular germ cell tumors present with progressive, painless enlargement of the testis. They may grow slowly or with appalling speed. Sometimes, the initial presentation is in the form of a metastatic deposit in the retroperitoneum [slideshare.net]
For tumors in the sex cord-stromal category (with the exception of the juvenile granulosa cell tumor) specify if adverse prognostic features are present or absent. [nature.com]
All endodermal sinus tumors presented AFP elevation at diagnosis. In patients with mixed tumors, three presented high AFP and β-HCG, one presented high AFP, and two presented high β-HCG. [scielo.br]
Case presentation A 36-year-old Caucasian man presented to our institution with an acutely developed severe pain in his right testis. [jmedicalcasereports.biomedcentral.com]
Entire Body System
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Intermittent Claudication
claudication intestine intracranial joint joint prosthesis kidney knee laceration lacrimal lower limb lung malignant molar pregnancy multiple muscle Neoplasm nerve newborn nondisplaced nontraumatic obstetrical trauma obstruction organ Osteochondrosis [books.google.com]
Musculoskeletal
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Back Pain
pain Cancer usually affects only one testicle. [mayoclinic.org]
Lower back pain, shortness of breath, chest pain, and bloody sputum or phlegm can be symptoms of later-stage testicular cancer. Swelling of 1 or both legs or shortness of breath from a blood clot can be symptoms of testicular cancer. [cancer.net]
Less common symptoms include: feeling of heaviness in the scrotum swelling or lump in the testicle change in the size or shape of the testicle feeling of unevenness pain or ache in the lower abdomen, the testicle or scrotum back pain enlargement or tenderness [cancer.org.au]
Skin
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Night Sweats
In 25-41% of patients the disease presentation is with fever, night sweats, and weight loss but are more frequent in the advanced stage 39, 40, 41. The involvement of retroperitoneal lymph nodes often leads to pain and ascites 42. [wcrj.net]
Urogenital
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Testicular Mass
Leukemia, lymphoma, and metastases may also present as testicular masses. [sonoworld.com]
Occasionally, a testicular mass can be mistaken for normal scrotal anatomy in a pathologic state. [cancertherapyadvisor.com]
Conclusion Currently, no typical ultrasound features can definitively distinguish intratesticular adenomatoid tumors from malignant testicular masses. [eurjmedres.biomedcentral.com]
Seminomas commonly metastasize through the lymphatic system and patients might present with signs of disseminated disease rather than a testicular mass. [lecturio.com]
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Scrotal Mass
A scrotal mass is an abnormal bulge or lump inside your scrotum. The scrotum is a sac of skin that contains your testicles. A scrotal mass can be a swollen testicle or it can contain fluid or other tissue. [healthline.com]
All new scrotal masses whose onset was sudden in nature should be considered torsion until proven otherwise. [cancertherapyadvisor.com]
Testicular cancer begins as a scrotal mass, which is usually not painful. Diagnosis is by ultrasonography. [msdmanuals.com]
H&E stain 20x Spermatoceles can be discovered as incidental scrotal masses found on physical examination by a physician. They may also be discovered by self-inspection of the scrotum and testicles. [en.wikipedia.org]
[…] from other scrotal masses, including testicular germ cell tumors. [ncbi.nlm.nih.gov]
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Scrotal Pain
The main manifestations were testicular tumor and scrotal pain. [scielo.br]
Indications include the following [10] : Evaluation of scrotal pain, including but not limited to testicular trauma, ischemia/torsion, and infectious or inflammatory scrotal disease. [emedicine.medscape.com]
An infarcted right testicle was confirmed at surgeryFigure 9a Figure 9b Testicular infarction mimicking a testicular mass in a 24-year-old man who presented with a 2-day history of right scrotal pain. [pubs.rsna.org]
Approximately 10 percent of males present with gynecomastia from tumors that secrete beta human chorionic gonadotropin (β-HCG). 14, 15 In any patient with a testicular mass, or unexplained scrotal pain or swelling, an ultrasonogram of the scrotum should [aafp.org]
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Painless Testicular Mass
We report a case of 52-year-old male patient with a history of human immunodeficiency virus who presented with a painless, testicular mass for 2 months. [ncbi.nlm.nih.gov]
Most common germ cell tumor Mean age is 40 yrs Very rare in children Patients present with painless testicular mass 30 % have metastases at presentation, but only 3% have symptoms related to metastases. 11. [slideshare.net]
A painless testicular mass is the classic presentation for testicular cancer, although a number of patients present with diffuse pain or swelling. Ultrasonography may be helpful in confirming the presence of a scrotal mass within the testicle. [aafp.org]
Most of the patients with AGCT presented with slowly growing painless testicular masses with several of whom reporting a duration of symptoms for many years [7, 22, 30]. [hindawi.com]
Because testicular malignancies are much more common than epidermoid cysts, a painless testicular mass, especially in a young man, is more likely a malignancy. [pubs.rsna.org]
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Testicular Pain
Testicular pain and/or abdominal pain. Dragging sensation. Recent history of trauma; it is probably the trauma that leads the man to examine himself and find the tumour rather than being the cause of malignant change. Hydrocele. [patient.info]
Any severe testicular pain or injury warrants a visit to a hospital emergency department. A change in the appearance or an examination of the testicle should prompt a visit to your health-care provider. [emedicinehealth.com]
The presenting symptom of testicular pain can be attributed to haemorrhage and haematoma formation and thus the pressure applied to the testicle during tumour formation [ 8 ]. [omicsonline.org]
Workup
Review Topic QID: 106375 5 No further workup, instruct patient to return if symptomatic M1 Select Answer to see Preferred Response PREFERRED RESPONSE 2 Sorry, this question is for PEAK Premium Subscribers only ARTICLES (4) VIDEOS (1) Topic COMMENTS (12 [medbullets.com]
Metastatic workup was done: contrast-enhanced computed tomography of whole abdomen and pelvis was within normal limits. [jcmtjournal.com]
These patients should undergo a full course of antibiotics and if the swelling is not resolved after that, they should undergo further workup to exclude possible testicular tumor. [lecturio.com]
Laboratory workup disclosed no abnormal results. [hindawi.com]
Treatment
Treatment options include surgery, radiation and/or chemotherapy. Regular exams after treatment are important. Treatments may also cause infertility. [icd10data.com]
Sometimes fertility can be interrupted by the treatments for both types of testicular germ cell tumours. For more information on fertility and cancer treatment visit our fertility info for men page. [canteen.org.au]
Treatment options include: Surveillance Surgery Radiation Chemotherapy Before any treatment starts, men should talk with their urologist about if they want to have a child. [urologyhealth.org]
These figures apply only to men who receive appropriate treatment for their cancer. Prompt diagnosis and treatment are essential. [emedicinehealth.com]
Prognosis
Seminoma late metastasis and excellent prognosis Embryonal worse prognosis than seminoma Choriocarcinoma worst prognosis in contrast to good prognosis in females metastasizes to lungs Please rate topic. [medbullets.com]
Prognosis of Testicular Cancer Prognosis is ranked good, intermediate or poor for non-seminoma tumors on some parameters Good prognosis is seen in: Primary testicular or retroperitoneal lesion No nonpulmonary visceral metastases low level of tumor markers [lecturio.com]
NSGCT: Patients with good-prognosis metastatic NSGCT should receive three cycles of BEP chemotherapy. [patient.info]
Cases with intermediate prognosis should be treated with cycles of chemotherapy, whilst those with poor prognosis should be treated with one cycle of chemotherapy before reassessment (those with marker decline should have continued chemotherapy cycles [teachmesurgery.com]
Prognosis for testicular cancer Prognosis means the expected outcome of a disease. An individual's prognosis depends on the type and stage of cancer as well as their age and general health at the time of diagnosis. [cancer.org.au]
Etiology
Manifestation code identifies conditions for which it is important to record both the etiology and the symptom of the disease. [books.google.com]
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
ICD-10-CM Codes › C00-D49 Neoplasms › C60-C63 Malignant neoplasms of male genital organs › Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]
Urinalysis, urine culture and complete blood count help to differentiate infectious etiologies from non-infectious etiologies. Furthermore, in the case of infectious etiologies, urine culture results guide antimicrobrial selection. [cancertherapyadvisor.com]
The publications considered in this overview are reliable scientific articles on the etiology of testicular cancer from different parts of the world. [onlinelibrary.wiley.com]
Epidemiology
Testicular cancer Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Testicular cancer from other Diseases Epidemiology and Demographics Risk Factors Screening Natural History, [wikidoc.org]
Epidemiology 1996 ;7: 14 - 19 20. Swerdlow AJ, Higgins CD, Pike MC. Risk of testicular cancer in cohort of boys with cryptorchidism. BMJ 1997 ;314: 1507 - 1511 [Erratum, BMJ 1997;315:1129.] 21. [nejm.org]
Testicular tumors are rare and correspond to 1-2% of solid pediatric tumors in males.5 According to the Surveillance, Epidemiology, and End Results (SEER) program, from the U.S. [scielo.br]
This data briefing examines the epidemiology of the main types of testicular tumours, and considers the likely impact of such a change in coding. [ncin.org.uk]
Introduction Testicular tumors can be of germ cell or non-germ cell origin germ cell origin are the majority (95%) and are more commonly malignant non-germ cell origin usually benign Epidemiology incidence most common cancer in men between 15-35 years [medbullets.com]
Pathophysiology
Testicular cancer Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Testicular cancer from other Diseases Epidemiology and Demographics Risk Factors Screening Natural History, [wikidoc.org]
Pathophysiology of Testicular Cancer The exact cause of testicular cancer is unknown. [lecturio.com]
Pathophysiology The cause of testicular cancer is not known. The characteristic genetic change found is an isochromosome of the short arm of chromosome 12 [i(12p)], which is often seen in sporadic cancers. [emedicine.medscape.com]
Prevention
Secondary Prevention Cost-Effectiveness of Therapy Future or Investigational Therapies Case Studies Case #1 Testicular cancer On the Web Most recent articles Most cited articles Review articles CME Programs Powerpoint slides Images American Roentgen [wikidoc.org]
Prevention There's no way to prevent testicular cancer. Some doctors recommend regular testicle self-examinations to identify testicular cancer at its earliest stage. But not all doctors agree. [mayoclinic.org]
Causes, Risk Factors, and Prevention Learn about the risk factors for testicular cancer and if there are things you can do that might help lower your risk. Early Detection, Diagnosis, and Staging Know the signs and symptoms of testicular cancer. [cancer.org]
Prevention Preventing most cases testicular cancer is not possible, as the causes are largely unknown. Many men who develop testicular cancer do not have any known risk factors. [medicalnewstoday.com]