At present, the name applied by Tuerk, "malignant neutropenia," seems [jamanetwork.com]

The symptoms of infection can have an atypical presentation in patients with neutropenia due to the less local inflammation; hence pus and fluctuance may be absent. [news-medical.net]

Fever, thoracic pain, dyspnoea and cough were the most frequent presenting symptoms. At the onset, 89% patients were neutropenic (neutrophil counts < 0.5 x 10(9)/l) with a median duration of previous neutropenia of 14 d (range 6-60). [pubmed.ncbi.nlm.nih.gov]

Outcome of colon cancer initially presenting as colon perforation and obstruction. World J Surg Oncol. 2017; 15(1):164. Lee YC, Jivraj N, Wang L, Chawla T, Lau J. [revistas.upb.edu.co]

Delayed Nasdaq - 01:00 2022-11-25 pm EST 1.800 USD +4.05% X4 Pharmaceuticals : Q3 2022 Earnings Presentation 912.4 KB 11/03/2022 | 08:13am EST 3Q 2022 Earnings Call: The Road to 4WHIM Data and Beyond November 3, 2022 Forward-Looking Statements This presentation [marketscreener.com]

• Fever

  One of the symptoms can be fever, which constitutes a possibly severe life-threatening situation in which overwhelming infection may ensue rapidly. [news-medical.net]

  Fever, thoracic pain, dyspnoea and cough were the most frequent presenting symptoms. At the onset, 89% patients were neutropenic (neutrophil counts < 0.5 x 10(9)/l) with a median duration of previous neutropenia of 14 d (range 6-60). [pubmed.ncbi.nlm.nih.gov]

  Antimicrobial prophylaxis and outpatient management of fever and neutropenia in adults treated for malignancy: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol. 2013; 31(6):794-810. [revistas.upb.edu.co]

  Episodes of fever in neutropenia in pediatric patients with cancer in Bern, Switzerland, 1993-2012. Sci Data. 2019 Jan 15;6:180304. [PMC free article: PMC6335615] [PubMed: 30644854] 16. [ncbi.nlm.nih.gov]

Review of evolving etiologies, implications and treatment strategies for the superior vena cava syndrome. Springerplus. 2016; 29;5:229. Oh IJ, Park CK, Kim YC. [revistas.upb.edu.co]

An analysis of factors influencing outcome demonstrated that the resolution of chemotherapy-induced neutropenia and prolonged treatment with amphotericin B and, if feasible, radical surgical debridement treatment, were significantly correlated with recovery [pubmed.ncbi.nlm.nih.gov]

Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine. Ther Adv Drug Saf. 2018; 9(5): 237-56. [ Links ] 5. Mehta TM, Van Lieshout RJ. [scielo.org.pe]

Neutropenia that is drug-induced usually resolves within days to weeks upon the discontinuation of treatment, and after viral infection bodies can build up their neutrophil level on their own again. [news-medical.net]

Extensive and aggressive diagnostic and therapeutic procedures are essential to improve the prognosis in these patients. [pubmed.ncbi.nlm.nih.gov]

prognosis of neutropenia disorders depends on the cause and organs involved. [ncbi.nlm.nih.gov]

Review of evolving etiologies, implications and treatment strategies for the superior vena cava syndrome. Springerplus. 2016; 29;5:229. Oh IJ, Park CK, Kim YC. [revistas.upb.edu.co]

This activity reviews the etiology, presentation, evaluation, and management/prevention of neutropenia, and reviews the role of the interprofessional team in evaluating, diagnosing, and managing the condition. [ncbi.nlm.nih.gov]

Meta- analysis examining the epidemiology of clozapine-associated neutropenia. Acta Psychiatr Scand. 2018; 138(2): 101-9. [ Links ] 17. Inada K, Oshibuchi H, Ishigooka J, Nishimura K. [scielo.org.pe]

Metastatic spinal cord compression: Incidence, epidemiology and prognostic factors. Rev Clin Esp. 2019; 219(7):386-9. Silva G, Bergmann A, Thuler L. [revistas.upb.edu.co]

A shift has been noted in the epidemiology infectious agents since the widespread use of empiric antibiotic therapy – highly lethal, gram-negative bacilli were superseded by indolent, gram-positive bacterial and fungal pathogens. [news-medical.net]

Chronic Granulomatous Disease: Epidemiology, Pathophysiology, and Genetic Basis of Disease. J Pediatric Infect Dis Soc. 2018 May 09;7(suppl_1):S2-S5. [PMC free article: PMC5946813] [PubMed: 29746675] 9. [ncbi.nlm.nih.gov]

Diagnosis, pathophysiology and management of hypercalcemia in malignancy: A review of the literature. Horm Metab Res 2019; 51(12):770-8. Pfennig CL, Slovis CM. Electrolyte disorders. In Marx J, Hockberger R, Walls R. [revistas.upb.edu.co]

A "hyper-dense" population of immune cells in the bone marrow, reducing the ability to achieve a healthy immune response No targeted therapies approved to treat underlying cause / pathophysiology Current treatments do not address mechanism of disease [marketscreener.com]

Chronic Granulomatous Disease: Epidemiology, Pathophysiology, and Genetic Basis of Disease. J Pediatric Infect Dis Soc. 2018 May 09;7(suppl_1):S2-S5. [PMC free article: PMC5946813] [PubMed: 29746675] 9. [ncbi.nlm.nih.gov]

Adverse effects of clozapine in older patients: epidemiology, prevention and management. Drugs Aging. 2014; 31(1): 11-20. [ Links ] 8. Haddad PM, Sharma SG. Adverse effects of atypical antipsychotics: differential risk and clinical implications. [scielo.org.pe]

Therapeutic use of these cytokines among patients hospitalized for established neutropenia may complement the recommended prophylactic use of these agents for the prevention of neutropenic episodes. [news-medical.net]

NCCN Clinical Practice Guidelines in Oncology: Prevention and Treatment of Cancer-Related Infections. v2.2017 [Internet]. 2017 [citado el 5 de febrero de 2021]. Disponible en: https://www.nccn.org/professionals/physician_gls/pdf/infections.pdf. [revistas.upb.edu.co]

[…] underlying cause / pathophysiology Current treatments do not address mechanism of disease Treatments include antibiotics, G-CSF, and immunoglobulins; do not correct lymphopenia, are not effective against HPV related- disease, have no effect on cancer prevention [marketscreener.com]

This activity reviews the etiology, presentation, evaluation, and management/prevention of neutropenia, and reviews the role of the interprofessional team in evaluating, diagnosing, and managing the condition. [ncbi.nlm.nih.gov]