We present two cases of gestational choriocarcinoma, showing some of these unusual presentations of a primarily gynecological problem. [ncbi.nlm.nih.gov]

Prognosis of gestational choriocarcinoma largely depends upon early diagnosis of the disease, comprehensive metastatic workup, selection of appropriate regimen of chemotherapy from outset and carefully planned follow up. [ayubmed.edu.pk]

See Workup for more detail. Management Patients with GTN are subdivided into 2 groups: those with a WHO score of less than 7 (low-risk) and those with a score of 7 or higher and who are at high risk of therapy failure. [emedicine.medscape.com]

The patient had no detectable metastasis or evidence of recurrence 15 months after treatment, which involved surgery without adjuvant chemotherapy. [ncbi.nlm.nih.gov]

The type of treatment used depends on where the cancer recurs and what treatment the woman has already received. [cancer.org]

Talk with your doctor about the goals of each treatment and what you can expect while receiving the treatment. Learn more about making treatment decisions. [cancer.net]

Non-gestational choriocarcinoma carries a bad prognosis than GCO. We present a case of NGCO who had pulmonary metastasis. [ncbi.nlm.nih.gov]

Prognosis depends upon early diagnosis and management. [ayubmed.edu.pk]

[…] several rare carcinomas to do so lungs are most common site gestationally derived masses have good prognosis non-gestationally derived masses have worse prognosis Presentation Symptoms vaginal bleeding Physical exam uterine enlargement Evaluation Labs [medbullets.com]

Etiology Etiology is not known. Diagnostic methods Histologically, choriocarcinoma is characterized by trophoblast proliferation, absence of chorionic villi and tissue necrosis with bleeding. [orpha.net]

Differentiation between two etiologies of primary choriocarcinoma can be achieved with DNA polymorphic analysis and it is necessary to distinguish between them to approach to an appropriate treatment of a patient. [ncbi.nlm.nih.gov]

Etiology In the case of gestational choriocarcinoma, approximately 5% of cases of complete hydatidiform mole are followed by choriocarcinoma. Only about half the cases of choriocarcinoma arise from a complete hydatidiform mole. [radiopaedia.org]

Etiology, pathogenesis 50% cases of choriocarcioma arise in complete mole, 25% follow normal term pregnancy, 25% follow spontaneous abortion. Extremely rare are cases arising in ectopic pregnancy. [atlases.muni.cz]

METHODS: Overall and 5-year average age-adjusted incidence rates were computed with the Surveillance, Epidemiology, and End Results program public-use database. [ncbi.nlm.nih.gov]

Summary Epidemiology Annual incidence and prevalence are not known. [orpha.net]

Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole. Am J Obstet Gynecol. 2010;203(6):531-9. [aulamedica.es]

Clinical and Epidemiological Investigations, Brian E. Henderson, C. Paul Morrow, Charles B. Hammond, Ernest I. Kohorn and Donald F. [cancerres.aacrjournals.org]

Pathophysiology and Etiology Choriocarcinoma recapitulates placental tissue development. [emedicine.medscape.com]

(Lurain, 2010) return to top Pathophysiology Choriocarcinoma is an invasive, highly vascular, anaplastic trophblastic tissue made up of cytotrophoblasts and syncitotrophoblasts that secrete human chorionic gonadotropin (hCG) in high amounts (Goldstein [sharinginhealth.ca]

Pathophysiology Hydatidiform mole Hydatidiform moles are chromosomally abnormal gestations caused by faulty fertilization of the oocyte. [clinicaladvisor.com]

One of the major unresolved problems in high-risk choriocarcinoma is the prevention of hemorrhage from tumor necrosis during chemotherapy. [ncbi.nlm.nih.gov]

Prevent and plan for potential complications associated with the advancing age of pregnant women. [books.google.com]

Prevention There is no known means of prevention. However, early detection of the symptoms and prompt medical treatment can improve the odds of survival. Key terms Biopsy — A sample of an organ taken to look for abnormalities. [medical-dictionary.thefreedictionary.com]

MAR 09, 2021 A study recently published in the Asian Pacific Journal of Cancer Prevention reports that Chinese Americans are fac ... [labroots.com]