Dysplasia is the earliest form of lesion which pathologists can recognize in a pap smear or in a biopsy. Dysplasia can be low grade or high grade, the risk of low grade dysplasia transforming into high grade dysplasia, and eventually cancer, is low. [wikivisually.com]

Low testosterone/hypogonadism in males [ edit ] Some males have had undescended testes but in all cases, whether or not this was corrected, they have hypogonadism (reduced function of the testes) and many may be infertile due to inadequate testicular [en.wikipedia.org]

Affected individuals may also have a high-pitched voice. Some individuals may experience delayed sexual maturation. The progeroid appearance may be more pronounced in individuals with mandibuloacral dysplasia type B. [rarediseases.org]

Affected individuals may also have a high-pitched voice. Some individuals may experience delayed sexual maturation. The progeroid appearance may be more pronounced in individuals with mandibuloacral dysplasia type B. [rarediseases.org]

Examples would be, bad breath links to halitosis, heart attack to myocardial infarction, where appropriate, these MeSH terms are automatically expanded, that is, include more specific terms. [wikivisually.com]

At 9 years of age, tight skin around his cheeks, hepatic steatosis and mild liver dysfunction were noted. [nature.com]

Dry eyes and the failure to close eyes during sleep can be a feature due to the loss of fat around the eyes (rather than any excessive prominence of the eyeballs). Limbs appear very thin due to lack of fat storage and also reduced muscle mass. [en.wikipedia.org]

The thin skin means if there is trauma there should be rapid attention to any wounds to avoid infection and help primary healing as there can be problems with skin ulcers. [en.wikipedia.org]

The thin skin means if there is trauma there should be rapid attention to any wounds to avoid infection and help primary healing as there can be problems with skin ulcers. [en.wikipedia.org]

He presented with prominent eyes, beaked nose, mandibular hypoplasia, crowded teeth, small mouth and testicular hypoplasia. He was also diagnosed with moderate sensorineural bilateral hearing loss and he started to wear hearing aids. [nature.com]

80%-99% of people have these symptoms Broad forehead Increased width of the forehead Wide forehead [ more ] 0000337 Congenital generalized lipodystrophy 0009059 Convex nasal ridge Beaked nose Beaklike protrusion Hooked nose Polly beak nasal deformity [rarediseases.info.nih.gov]

He presented with prominent eyes, beaked nose, mandibular hypoplasia, crowded teeth, small mouth and testicular hypoplasia. He was also diagnosed with moderate sensorineural bilateral hearing loss and he started to wear hearing aids. [nature.com]

80%-99% of people have these symptoms Broad forehead Increased width of the forehead Wide forehead [ more ] 0000337 Congenital generalized lipodystrophy 0009059 Convex nasal ridge Beaked nose Beaklike protrusion Hooked nose Polly beak nasal deformity [rarediseases.info.nih.gov]

He presented with prominent eyes, beaked nose, mandibular hypoplasia, crowded teeth, small mouth and testicular hypoplasia. He was also diagnosed with moderate sensorineural bilateral hearing loss and he started to wear hearing aids. [nature.com]

80%-99% of people have these symptoms Broad forehead Increased width of the forehead Wide forehead [ more ] 0000337 Congenital generalized lipodystrophy 0009059 Convex nasal ridge Beaked nose Beaklike protrusion Hooked nose Polly beak nasal deformity [rarediseases.info.nih.gov]

Methods We report here the clinical description of a woman with a rare severe lipodystrophic and progeroid syndrome associated with hypertriglyceridemia and diabetes whose genetic bases have been clarified through whole-exome sequencing (WES) analysis [iths.pure.elsevier.com]

Abstract BACKGROUND: Lipodystrophies are a large heterogeneous group of genetic or acquired disorders characterized by generalized or partial fat loss, usually associated with metabolic complications such as diabetes mellitus, hypertriglyceridemia and [ncbi.nlm.nih.gov]

Abstract Lipodystrophies are a large heterogeneous group of genetic or acquired disorders characterized by generalized or partial fat loss, usually associated with metabolic complications such as diabetes mellitus, hypertriglyceridemia and hepatic steatosis [infona.pl]

DOI: 10.1016/j.metabol.2015.07.022 BACKGROUND Lipodystrophies are a large heterogeneous group of genetic or acquired disorders characterized by generalized or partial fat loss, usually associated with metabolic complications such as diabetes mellitus, hypertriglyceridemia [semanticscholar.org]

In a collaborative trial with the National Institutes of Health (NIH), we showed that leptin-replacement therapy was beneficial for improving hyperglycemia (increased levels of blood sugar), hypertriglyceridemia (increased levels of blood lipids), insulin [utsouthwestern.edu]

Individuals at average-risk for colorectal cancer should have another screening after ten years if they get a normal result, dysplasia is characterised by four major pathological microscopic changes, Anisocytosis Poikilocytosis Hyperchromatism Presence [wikivisually.com]

Individuals at average-risk for colorectal cancer should have another screening after ten years if they get a normal result, dysplasia is characterised by four major pathological microscopic changes, Anisocytosis Poikilocytosis Hyperchromatism Presence [wikivisually.com]