It presents as a well-circumscribed mass in the buccal mucosa, tongue, floor of the mouth or hard palate. There are only two case reports of SCL in the gingiva and alveolar ridge. [nature.com]

In our case, the patient was 65 years female and presented with the tumour in left mandible. The clinical presentation depends on location, size and spread of tumour. [bmrat.org]

Odontogenic fibroma Similar peak age of presentation Can also have spindled cells but usually more cellular and fibrocollagenous with strands of odontogenic epithelium Calcifications can be seen in the epithelium Osteochondromyxoma Usually present in [pathologyoutlines.com]

Pain was present in 8 cases but did not correlate with pathologic diagnosis in our study. Nonetheless, both malignant tumors in our series did present with pain. [jamanetwork.com]

Indian J Dent Res 2011;22:616 Osteochondroma (OC) is one of the most common benign tumors of the axial skeleton, but it is rarely present in the facial bones. [ijdr.in]

• Cervical Lymphadenopathy

  Cervical lymphadenopathy was absent. Cone Beam Computed Tomography was taken by SCANORA 3D CBCT machine (SOREDEX, Helsinkey, Finland) with 7.5x10 cm field of view, 200 microns voxwl size, 90 KVP and 8 mA. [pubs.sciepub.com]

  Extra orally, there were no clinical signs of cervical lymphadenopathy. The orthopantomogram was negative for bone lesion. Past medical history included a partial colectomy for an adenocarcinoma 10 months earlier. [peertechz.com]

  The CECT report was suggestive of malignant neoplasm of the left parotid gland metastatic cervical lymphadenopathy and mandibular metastasis. [amsjournal.com]

  Cervical lymphadenopathy was absent. [wjso.biomedcentral.com]

• Localized Pain

  Premalignant leukoplakia or erythroplasia or a painless nonhealing ulcer may be the first sign of oral cancer; localized pain usually occurs later, but lymph nodes may be involved early in the course. [medical-dictionary.thefreedictionary.com]

  pain or mobility • More often is undifferentiated and does not resemble primary lesion and difficult to tell primary • Immunohistochemistry is important • Prognosis is poor; most patients die within a year 70. [slideshare.net]

  The most common presenting symptoms are swelling at the site of disease, which is almost universally present, and local pain, reported by approximately 70% of the patients. [intechopen.com]

• Fatigue

  The pain and fatigue kept Matthew away from work for months. Because his jaw was wired shut, he subsisted on a liquid diet, first through a syringe and later through a straw. [utswmed.org]

• Sore Throat

  Other side effects include: a sore throat- due to mouth ulcers, pain on swallowing, a dry mouth- due to damage caused to the salivary glands (which are in charge of making the saliva), taste changes, a hoarse voice and effect on the sense of smell. [medical-dictionary.thefreedictionary.com]

  Signs and Symptoms Diagnosis Treatment Symptoms may include: Reddish patches, called erythroplasia Whitish patches, called leukoplakia A sore that does not heal and bleeds easily A lump or thickening of the tissues Chronic sore throat or hoarseness Difficulty [ucsfhealth.org]

  Other symptoms include sore throat, sores around the jaw and difficulty of swallowing or chewing Causes & Risk Factors The development of jaw cancer is associated with mutations in the oncogenes. [cancerwall.com]

• Hoarseness

  Other side effects include: a sore throat- due to mouth ulcers, pain on swallowing, a dry mouth- due to damage caused to the salivary glands (which are in charge of making the saliva), taste changes, a hoarse voice and effect on the sense of smell. [medical-dictionary.thefreedictionary.com]

  Signs and Symptoms Diagnosis Treatment Symptoms may include: Reddish patches, called erythroplasia Whitish patches, called leukoplakia A sore that does not heal and bleeds easily A lump or thickening of the tissues Chronic sore throat or hoarseness Difficulty [ucsfhealth.org]

  Rare findings include the inability to open the mouth (trismus) or dysphonia, a voice disorder characterized by hoarseness, weakness, tingling or numbness (paresthesia), and, in rare cases, voice loss (my note: disruption of the voice because of laryngeal [rarediseases.org]

• Pharyngitis

  Demographics and occurrence of oral and pharyngeal cancers. The outcomes, the trends, the challenge J Am Dent Assoc. 2001;(132 suppl):7S–11S. Copyright 2007 by the American Academy of Family Physicians. This content is owned by the AAFP. [aafp.org]

• Odynophagia

  However, mandibular radiolucency remained unchanged on imaging 5 years later Case two was a 26-year-old male presenting with pain, odynophagia and swelling of the left ascending ramus. [imj.ie]

• Jaw Pain

  Jaw pain A tumor is one explanation for pain in the jawbone, and this pain can make it hard for you to eat and chew. [colgate.com]

  Matthew Ladin of Dallas contacted his dentist about his nagging jaw pain, thinking it was probably just a toothache. “It felt like I had another wisdom tooth coming in. [utswmed.org]

  In the presence of an ambiguous sign in oral cavity such as jaw pain or paresthesia, diagnostic examination of malignancy is recommended. [ijp.iranpath.org]

  Jaw pain may radiate to the neck or elsewhere in the face if the tumor is near a facial nerve. Depending on the location of the tumor within the jaw, chewing may trigger increased pain. [livestrong.com]

• Poor Oral Hygiene

  Predisposing factors are alcoholism; heavy use of tobacco; poor oral hygiene; ill-fitting dentures; syphilis; Plummer-Vinson syndrome; betel nut chewing; and, in lip cancer, pipe smoking and overexposure to sun and wind. [medical-dictionary.thefreedictionary.com]

  Others include poor oral hygiene, irritation caused by ill-fitting dentures, rough surfaces on teeth and poor nutrition. [ucsfhealth.org]

  Poor oral hygiene can also be concluded based on mineral deposits on the surface of tooth crowns (calculus), and consequential atrophic changes at the cervical level within the lamina dura. [aclr.com.es]

• Xerostomia

  Bario-reflex dysfunction Candida Infection Carotid Artery Stenosis Dysphagia Esophageal Stricture Lymphedema Mandibular Sarcoma Mucositis Myelodysplastic Syndrome Neutropenia Osteoradionecrosis Periodontal Issues Radiation Caries Stomatitis / Fibrosis Trismus Xerostomia [oralcancerfoundation.org]

  Other clinical complications due to head and neck RT were xerostomia (51.2%), mucositis (11.2%), complete loss or reduction in taste (38%), oral candidiasis (8.8%), and pain (5.6%). None of the subjects had paresthesia. [ijdr.in]

• Subcutaneous Mass

  Differential diagnosis SCL typically occurs as a solitary, painless and slow growing subcutaneous mass in the posterior neck or back of elderly males. [nature.com]

• Neglect

  If so, consult your GP however don't be alarmed as it isn't necessarily cancer, though it's always better to check it out and not neglect it. Q. What is radiotherapy? My Grandfather had a surgery to remove a cancerous tumor on his cheek. [medical-dictionary.thefreedictionary.com]

  Neglected Ameloblastomas: A Case Report. Med Buccale Chri Buccale. 2012; 18: 161-165. Available at: ... 10. Philipose, T.R, Somayaji, B.V, Pai, M.R, Monteiro, F, Bhagavath, P, Hegde, P, Raj, B, Shetty, S. [bcrt.org.uk]

  Tumors that are neglected may portend a worse prognosis and progressively involve the skin of the mentum, alveolar mucosa, mandible, floor of mouth, and tongue, as well as locoregional nodal and distant metastasis. [med.uth.edu]

  Such symptoms should not be neglected and advanced imaging methods should be used with the thought that it may be neoplasia. Also the clinical symptoms and radiological appearance of many tumors are similar. [intechopen.com]

• Seizure

  Stopping alcohol suddenly can cause seizures, delirium, and death. If we know you are at risk for these complications, we can prescribe medication to help prevent them. [mskcc.org]

Her general physical examination did not reveal any significant abnormality & her laboratory workup was within normal range. [ispub.com]

After identification of a jaw mass, workup in most cases began with an incisional biopsy prior to attempting a definitive procedure. [jamanetwork.com]

Metastatic workup is not routinely indicated because fewer than 2% of patients have distant metastasis at the time of presentation. Staging of lip cancers is performed by the TNM classification system of the AJCC. [med.uth.edu]

Other metastatic workup, including spiral CT scan of the thorax, abdomen, and pelvic area, were normal. She was started on doxorubicin/cyclophosphamide/5-FU chemotherapyy, and local irradiation of the left mandible was performed. [ijp.iranpath.org]

A complete workup followed, consisting of CT scans (face, neck, chest), upper and lower abdomen ultra sound and a skeletal scanning. The investigation proved negative for lesions elsewhere in the body. [peertechz.com]

This tumor can recur after treatment; however, aggressive surgical treatments will typically reduce the chance of recurrence. Central giant cell granuloma. [mayoclinic.org]

Treatment Removal of attached tooth and tumor is the method of treatment. No recurrences are reported. [emedicine.medscape.com]

Radical surgery seems to be the best treatment option to fibrosarcoma (1). Radiation therapy has been used as adjuvant treatment in unresectable tumors and chemotherapy is only used for palliative treatment (3,4). [scielo.isciii.es]

With current treatment techniques the recurrence rate is around 2-3%. Recurrence is usually seen within 5 years of treatment. [en.wikipedia.org]

Discussion ACC is a malignant epithelial tumor characterized by slow growth, late onset of metastasis, and poor prognosis. [tjmrjournal.org]

Survival Rate Duodenal Cancer – Symptoms, Prognosis, Survival Rate and Treatment Vaginal Cancer – Symptoms, Signs, Pictures, Treatment, Causes Tonsil Cancer – Pictures, Symptoms, Survival Rate, Staging, Prognosis Fallopian Tube Cancer – Symptoms, Prognosis [cancerwall.com]

It has a poor prognosis. The prognosis becomes worse if there is a delay in the diagnosis and treatment planning. [ccij-online.org]

The prognosis is poor and is based on the histological type, the depth at microscopic level of the tumor’s invasion and its localization. [jusurgery.com]

In conclusion, CMC of the mandible is extremely rare malignant salivary gland neoplasm and the prognosis is related to histologic grade ,clinical stage and adequate resection of the tumor. [pubs.sciepub.com]

The radiological investigations also suggested parotid gland tumour of benign etiology along with a fortuitous discovery of a Stafne bone defect in the right angle of mandible. [scielo.org.za]

[…] in females (1.5:1 to 2:1) First described in 1980's as jaw tumors that resembled metastatic clear cell renal carcinoma ( Head Neck Surg 1985;8:115 ) Sites Mandible most common site (75%) Soft tissue involvement common as lesion often perforates bone Etiology [pathologyoutlines.com]

The etiology of ameloblastoma is not known with certainty but the cells of origin are thought to be ameloblasts. [pocketdentistry.com]

Etiology of lipoma is not clear but possible etiological factors may be dental trauma, disruption of the post-extraction healing process, retention of radicular remains, medullary bone infarction (common in elderly) or osteoporotic bones [ 80, 81, 82 [intechopen.com]

[…] features Benign odontogenic myxoid lesion composed of spindled to stellate cells Third most frequent odontogenic tumor (after odontoma and ameloblastoma ) Recurrence rate 25% Terminology Odontogenic myxoma Odontogenic myxofibroma Odontogenic fibromyxoma Epidemiology [pathologyoutlines.com]

References Ottaviani G, Jaffe N (2009) The epidemiology of osteosarcoma. Cancer Treat Res 152: 3-13. Balwani SR, Tupaki JV, Barpande SR (2006) Parosteal osteosarcoma of the mandible. [omicsonline.org]

A 4-year prospective study on epidemiology and clinicopathological presentation of odontogenic tumors in Tanzania. Oral Surg Oral Med oral Pathog Oral radiol Endod. 2005;99:598-602. [revistas.unal.edu.co]

It is a tumor of mesenchymal origin and the epidemiologic factors are still unknown, but many authors report radiation therapy history as a possible one (3). [scielo.isciii.es]

Osteoradionecrosis of the jaws: Current understanding of its pathophysiology and treatment. Br J Oral Maxillofac Surg 2008;46:653-60. 4. Jereczek-Fossa BA, Orecchia R. Radiotherapy-induced mandibular bone complications. [ijdr.in]

Osteoradionecrosis prevention myths. Int J Radiat Oncol Biol Phys 2006;64:661-9. 7. Reuther T, Schuster T, Mende U, Kubler A. [ijdr.in]

[…] malignant transformation Erythroplakia 7 Red patch without obvious cause Refer for biopsy and surgical excision No evidence that surgical excision prevents malignant transformation Squamous cell carcinoma 8 Nonhealing ulcer or mass Refer for biopsy, [aafp.org]

The best treatment for this is prevention at the time of the original mandible reconstruction. [headandneckcancerguide.org]

Intraoperative facial nerve monitoring is an effective method for preventing nerve weakness during such mandibular surgeries. [journals.lww.com]