Successful treatment of severe Crimean-Congo hemorrhagic fever with supportive measures without ribavirin and hypothermia. J Clin Virol. 2009 Feb. 44(2):181-2. [Medline]. Zampieri CA, Sullivan NJ, Nabel GJ. [emedicine.com]

Occasionally urine samples were collected directly from the bladder by aspiration with a syringe. The schedule for sample collection is given in Table 1. [doi.org]

After a gestation period of 105–7 days, females usually give birth to a single pup which is carried attached to a nipple on the female for 6 weeks, then left at the roosting site and fed with regurgitated food for 9–10 weeks, before flying and fending [doi.org]

As disease progresses, systemic (prostration, lethargy), gastrointestinal (anorexia, vomiting, abdominal pain, diarrhea), respiratory (chest pain, breath shortness, cough, nasal discharge), vascular (conjunctival injection, postural hypotension, edema [ncbi.nlm.nih.gov]

Animals found in the Goroumbwa mine included bats, rodents, shrews, frogs, snakes, cockroaches, crickets, spiders, wasps, and moth flies, although there was no history of direct exposure to animals or insect bites in any patient with Marburg hemorrhagic [doi.org]

Gross pathologic lesions included maculopapular cutaneous rash; pulmonary congestion and edema; pericardial effusion; enlarged, congested, and/or hemorrhagic lymphoid tissues; enlarged friable fatty liver; and pyloric and duodenal congestion and/or hemorrhage [ncbi.nlm.nih.gov]

Other factors, including increased fibrinogen, decreased protein C activity, thrombocytopenia, and coagulation disorder were observed in the hamster model. The target organs were the mesenteric lymph node, spleen, liver, and adrenal gland. [ncbi.nlm.nih.gov]

Gross pathologic lesions included maculopapular cutaneous rash; pulmonary congestion and edema; pericardial effusion; enlarged, congested, and/or hemorrhagic lymphoid tissues; enlarged friable fatty liver; and pyloric and duodenal congestion and/or hemorrhage [ncbi.nlm.nih.gov]

KEYWORDS: dual-color imaging; reverse genetics; viral inclusion bodies [ncbi.nlm.nih.gov]