Presentation Presenting features may include localising signs, generalised signs and false localising signs. A rapid onset of symptoms suggests a cerebrovascular lesion whilst a space-occupying lesion of the brain will usually be more gradual. [patient.info]

As many as 0.6% of patients present with PCNSL concurrent with the diagnosis of AIDS, and early estimates suggested that 2% to 6% of AIDS patients would ultimately develop the disorder. [ajnr.org]

Case Presentation A 35-year-old woman presented with headache and left-sided weakness. MRI scans initially mislead us to a diagnosis of glioblastoma (GBM). Surgery was performed. The mass was sub-totally resected. [wjso.biomedcentral.com]

CASE 2 An AfroCaribbean woman aged 33 presented with a cluster of four right sided sensorimotor seizures with secondary generalisation. On examination she was drowsy and had a mild right hemiparesis. [jnnp.bmj.com]

Signs and Symptoms Presenting complaints of patients with an intracranial neoplasm tend to be similar for primary brain tumors and intracranial metastases. [emedicine.medscape.com]

• Lymphadenopathy

  Further investigations showed normal blood levels of ionised calcium and serum angiotensin converting enzyme (ACE), but a mild lymphopenia (0.7×10 9 /l); chest radiography showed minimal hilar lymphadenopathy but spirometry and gas transfer were normal [jnnp.bmj.com]

• Blurred Vision

  In addition to headaches, increased pressure within the head can produce nausea, vomiting, lethargy, double or blurred vision and trouble with balance or walking. A man is laying in bed with a headache. [livestrong.com]

  Symptoms Caused by an Epidermoid May Include: Headaches – often worse in the morning or by changing positions; can be constant and become more severe or more frequent; not your typical headache Vision problems like blurred vision, double vision, or loss [epidermoidbraintumorsociety.org]

  Lesions of occipital lobe Any lesions of occipital lobe typical lead to the development of symptoms associated with vision. The affected person might experience blurring of vision. [medlicker.com]

  Symptoms include headaches, blurred vision, dizziness, and a slight numbness of the face. The symptoms are caused by a buildup of cerebrospinal fluid (CSF). Treatment is given to relieve the symptoms, particularly visual impairment. [braintumor.org]

• Tremor

  Intention tremor is worst at the end of a movement and leads to past-pointing. Ask the patient first to touch their nose with the index finger, and then your index finger, held about 50 cm away and back to their nose again. [patient.info]

  […] recognition, spatial orientation disorders), personality or emotional changes, hemiparesis, hypoesthesia, aphasia, ataxia, visual field impairment, impaired sense of smell, impaired hearing, facial paralysis, double vision, or more severe symptoms such as tremors [en.wikipedia.org]

• Slurred Speech

  Signs or symptoms vary depending on a child's age and the location of the tumor, but may include: vomiting seizures weakness of the face, trunk, arms, or legs slurred speech difficulty standing or walking poor coordination headache in babies and young [kidshealth.org]

  Sudden or rapid onset (minutes to hours) of slurred speech, weakness, and numbness of an extremity, or a facial droop may be seen with strokes. [emedicinehealth.com]

[…] include incompatibility with certain medical equipment, longer imaging times (increased risk of motion artifact), and poor visualization of the subarachnoid space Neither CT nor MRI can be used to differentiate tumor recurrence from radionecrosis See Workup [emedicine.medscape.com]

Any adult who has a recent onset of seizures, particularly focal seizures, is considered a tumor suspect until adequate neurologic workup proves otherwise. Specific Tumor Types There are many types of tumors that develop intracranially. [dartmouth.edu]

• Hyponatremia

  Cytotoxic Pump failure following reductions in CBF Interstitial Caused by high pressure hydrocephalus Hydrostatic Caused by an increase in transmural vascular pressure, loss of cerebral autoregulation Osmotic Secondary to a critical fall in osmolality or hyponatremia [openanesthesia.org]

Regular follow-up treatment is extremely important after treatment for a brain tumor. [radiologyinfo.org]

Surgery is the standard treatment. [braintumor.org]

Treatment for Pediatric Brain Tumors One or more of these approaches will be included in the child’s brain tumor treatment plan: Surgery Most brain tumors in infants and children require surgical removal, or at least a biopsy, as part of the treatment [hopkinsmedicine.org]

Treatment is key for spinal tumours, as any damage it causes can be made more severe or indeed, permanent, if treatment is not sought soon enough. [spinalcord.com]

You will also learn about the prognostic factors doctors use to help plan treatment. Use the menu to see other pages. [cancer.net]

Currently, the factors listed above are the best indicators of a patient’s prognosis. [cancer.net]

Discussing treatment and prognosis with an experienced neurologist (brain doctor) is a must. In general, the ability of a brain lesion to disappear or just shrink depends on the what the lesion is. [zocdoc.com]

Brain Lesions Prognosis Because of the many different types of brain lesions, the prognosis and outcomes of brain lesions are variable. [emedicinehealth.com]

Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options for primary brain and spinal cord tumors depend on the following: The type and grade of the tumor. [my.clevelandclinic.org]

Certain mutations provide better prognosis than others. IDH1 and IDH2 mutations in gliomas, as well as deletion of chromosome arms 1p and 19q, generally indicate better prognosis. [en.wikipedia.org]

Clinical Clues to Nonmalignant Brain Lesions Clinical clues Suggested etiology Abnormalities found on more extensive imaging that are suggestive of an etiology Cysticercosis, fungal infections, sarcoidosis, tuberculosis Chronic fever; recent dental procedure [aafp.org]

The spectrum of underlying etiologies of HIV-associated intracranial mass lesions is broad. [neurology.org]

Local inflammatory responses, vasculitis, and autoimmune mechanisms have been implicated in the etiology of Lyme neuroborreliosis. [canlyme.com]

Its etiology and pathogenesis are still unknown. It is very possible that viral infections initiate the inflammatory process that somehow becomes self-sustaining [ 5 ]. [wjso.biomedcentral.com]

In some instances, however, the symptoms are specific to the etiology. Hemorrhage, which can be parenchymal or extra-axial is the most common cause of intracranial mass lesions and is discussed in Chapter 27. [dartmouth.edu]

Epidemiologic studies conducted since the introduction of HAART suggest a decline in the incidence of PCNSL in the AIDS population. [ajnr.org]

Appel LJ, Braun LT, Chaturvedi S, Creager MA, Culebras A, Eckel RH, Hart RG, Hinchey JA, Howard VJ, Jauch EC, Levine SR, Meschia JF, Moore WS, Nixon JV, Pearson TA; American Heart Association Stroke Council; Council on Cardiovascular Nursing; Council on Epidemiology [passeportsante.net]

"Brain Tumor Epidemiology: Consensus from the Brain Tumor Epidemiology Consortium (BTEC)". Cancer. 113 (7 Suppl): 1953–68. doi : 10.1002/cncr.23741. PMC 2861559. PMID 18798534. ^ a b c "Cancer Stat Facts: Brain and Other Nervous System Cancer". [en.wikipedia.org]

Epidemiology of brain metastases. Current Oncology Reports, 14 (1), 48-54. Ramakrishna, N., Temin, S., Chandarlapaty, S., Crews, J. R., Davidson, N. E., Esteva, F. J., ... & Lin, N. U. (2014). [oncolink.org]

[…] percent of these cases were reported during the period 1981 to 1987, 41% during 1988 to 1992, and 49% during 1993 to October 31, 1995. 1 In 1990, an estimated one million individuals were infected with HIV in the United States, 2 and the more recent epidemiologic [neurology.org]

Reference article This is a summary article ; we do not have a more in-depth reference article. pathophysiology brain mass lesions are a very broad group of conditions infection (abscess) neoplastic brain metastases primary brain tumor (benign/slow growing [radiopaedia.org]

The exact pathophysiology of Lyme neuroborreliosis is unknown and may be multifactorial. In some specimens, the spirochete can be identified (6). [canlyme.com]

[…] energy emitted by the GSM (2G) phones that were in use when epidemiological studies that observed a slight increase in the risk for glioma – a malignant type of brain cancer – among heavy users of wireless and cordless telephones were conducted. [3] Pathophysiology [en.wikipedia.org]

How to Prevent Brain Lesions In some instances, certain brain lesions can be prevented, though not all types can be completely prevented. [emedicinehealth.com]

Collaborative Meta-Analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients. ‎ [books.google.es]

Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. [passeportsante.net]

Measures such as neck compression (tourniquet) and volume loading can be helpful in preventing VAE. PEEP increases the risk of VAE. [openanesthesia.org]

For this reason, researchers looked at utilizing whole brain radiation as a way to prevent future brain metastases from developing. [oncolink.org]