Computed tomography (CT) scan revealed an aggressive lesion in the right mandible with local soft tissues extension and cervical lymphadenopathy ( Figure 1 ). [omicsonline.org]

These complications or their symptoms, such as difficulty breathing, chest pain, poor growth or weight loss, and infection have sometimes been the first indications of the condition. The specific cause of Gorham's disease remains unknown. [en.wikipedia.org]

Aviv RI, McHugh K, Hunt J. Angiomatosis of bone and soft tissue: a spectrum of disease from diffuse lymphangiomatosis to vanishing bone disease in young patients. Clin Radiol. 2001 Mar;56(3):184-90. [lgdalliance.org]

Case History: A 40-year-old male patient presented himself in 2000 with a right-sided hearing loss and tinnitus for about nine month. He also developed dysphonia and dysphagia followed by headache and neck pain with nausea and emesis. [ashg.org]

Peculiar clinical episodes of a foul body odor with fever and erythematous skin lesions, presence of radiographic findings such as acro-osteolysis and periarticular erosions, and the absence of angiomatous or lymphangiomatous dysplasias at autopsy, indicate [ncbi.nlm.nih.gov]

Gorham's disease is a rare bone disorder characterized by bone loss (osteolysis), often associated abnormal blood vessel growth (angiomatous proliferation). Bone loss can occur in just one bone, or spread to soft tissue and adjacent bones. [rarediseases.info.nih.gov]

The book details the pathologic and radiologic characteristics of all bone and joint diseases, including arthritis, metastatic bone disease, osteoporosis, trauma, osteomyelitis, developmental bone disorders, and tumor-like lesions. [books.google.com]

How we care for Gorham-Stout disease With fewer than 300 known cases of Gorham-Stout, the majority of physicians will never encounter this rare bone disorder. [childrenshospital.org]

Disorder of continuity of bone of ankle Disorder of continuity of bone of fibula Disorder of continuity of bone of foot Disorder of continuity of bone of hand Disorder of continuity of bone of humerus Disorder of continuity of bone of pelvis Disorder [icd9data.com]

[…] vertical height of the mandibular body with the resorption extended towards the basal bone [1] [Figure 1]. [jomfp.in]

& cervical spine Lump in temporal region, head-ache, deafness, paraplegia, & Arnold-Chiari malformation Pamidronate, laminectomy, & RT Progression of disease; death from chylothorax Lekovic et al. (2006) 10 10 M Clivus, petrous, & C1–2 Painful neck, torticollis [jstage.jst.go.jp]

Upon examination, there were bilateral palpable submandibular lymph nodes with no obvious facial swelling. [omicsonline.org]

They further stated that their histopathological study provided good evidence that osteolytic changes seen in Gorham's disease are the result of hyperactive osteoclastic bone. [en.wikipedia.org]

Delling Hamburg University School of Medicine, Hamburg, Germany X Study provides good evidence of hyperactive osteoclastic bone resorption causing osteolytic changes. [psykick.de]

They further stated that their histopathological study provided good evidence that osteolytic changes seen in Gorham’s disease are the result of hyperactive osteoclastic bone. [lgdalliance.org]

Typical histological findings include local osteoclastic hyperactivity and proliferation of small thin-walled arterial or lymphatic vessels (angiomatosis) [ 3 – 7 ]; radiological features include massive progressive osteolysis that does not respect anatomical [hindawi.com]

Deep tendon reflexes were hyperactive and equal bilaterally in both upper and lower limbs. Bowel and bladder function was normal. Radiographs of the cervical spine revealed atlantoaxial dislocation due to osteolysis. [jstage.jst.go.jp]

These lesions were accompanied by neurologic manifestations in both the upper and lower extremities. Bone matrix collagen and noncollagenous proteins in this rare syndrome were analyzed. The pathogenesis of this rare phenomenon is discussed. [ncbi.nlm.nih.gov]

He then presented with facial hypoesthesia, deglutition disorder, and spastic gait. MRI revealed spinal cord and medulla oblongata compression at the level of the basilar impression. [jstage.jst.go.jp]

disorder Biopsy Progression of disease; death from transection of spinal cord at C4 Hoffman et al. (1980) 7) 7 F Petrous, sphenoid, & C1–2 Cerebrospinal fluid rhinorrhea, meningitis, torticollis, & headache RT AD; remineralization Kurczynski et al. [jstage.jst.go.jp]

J Oral Surg 29: 659–663, 1971 5) Girn HR, Towns G, Chumas P, Holland P, Chakrabarty A: Gorham’s disease of skull base and cervical spine—confusing picture in a two year old. [jstage.jst.go.jp]