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Massive Trauma

Massive Trauma (history)


Presentation

  • Conversely, this experience may present a risk of missing opportunities for healing and reintegrating victims into their societies, or, worse, (re)victimizing and (re)traumatizing them.[ncbi.nlm.nih.gov]
  • Proponents of the 1:1:1 ratio invoke the need to treat diligently the acute coagulopathy of trauma (ACT) which is present in approximately 25% of patients at the time they present in the emergency room.[nataonline.com]
  • Collection includes both citations and many full-text, downloadable documents from mid-1900s to present. AULIMP - Air University Library Index to Military Periodicals.[dtic.mil]
  • This makes democracy and human rights Sida’s largest thematic area, equivalent to approximately 30 % of Sida’s total disbursement ... 2017-12-21 Publication Evaluation of Sida’s ITP approach for Capacity Development This report presents the findings,[sida.se]
  • Table 2 presents the main characteristics of the patients according to their BMI classes.[journals.plos.org]
Fracture
  • After stabilization, a CT scan was performed a few hours later which showed a subdural hematoma on the right frontotemporal side, a Le Fort I facial fracture, C6 facet joint fracture, transverse process fractures of L2-L4, and several rib fractures on[ijcasereportsandimages.com]
  • An autopsy completed Friday shows Donald Harvey had several skull fractures and brain injuries.[local12.com]
  • One driver had a fractured leg, while the other sustained back and neck injuries. Singh and his son died on the scene from "massive blunt trauma".[news24.com]

Treatment

  • Four patents did not respond to rFVIIa treatment and exsanguinated within 24 hr. Two patients died after one week, one from sepsis and one from multi-organ failure.[ncbi.nlm.nih.gov]
  • Successful outcome requires treatment of surgical sources of bleeding, restoration of blood volume to maintain tissue perfusion and oxygenation, and correction of coagulopathy.[pennstate.pure.elsevier.com]
  • Once enrolled, patients were randomly chosen to receive either the control treatment, normal saline (salt water), which is the current standard of care (SOC), or the experimental treatment (AB-FP24 plasma) as the first treatment fluid.[denverhealth.org]
  • The urgent need for a predefined treatment of hemostasis, as well as a quick and safe anticoagulant treatment reversion in bleeding patients with or without trauma, and the availability of dynamic and quick diagnostic tests and algorithms to guide professionals[medintensiva.org]
  • Program Description Through the use of case studies, this session will review the progress and variability in treatment of trauma cases within the United States.[aabb.org]

Prognosis

  • Nevertheless, we still do not know if the ACT is simply a marker of the severity of trauma or a determinant of survival, i.e. no one has established that treating the ACT improves patient prognosis.[nataonline.com]
  • It may be concluded that the prognosis of the patients with the chest injuries depends on how fast they can be carried to the Emergency and Critical Care Medical Center.[dspace.lib.niigata-u.ac.jp]
  • The majority of preventable deaths from trauma result from unrecognised intra-abdominal bleeding. [70] Prognosis [ edit ] Trauma deaths occur in immediate, early, or late stages.[en.wikipedia.org]

Etiology

  • One must not confuse Mongolian spots with contusions and make a diagnosis of child abuse; if there is any question as to the etiology, the lesion should be incised.[emedicine.medscape.com]

Epidemiology

  • The project is planned and conducted in collaboration with the Department of Laboratory Medicine, Division of Clinical Immunology and Transfusion Medicine; the Department of Medical Epidemiology and Biostatistics; and the Coagulation Unit at the Department[ki.se]
  • Zwi , A. & Ugalde , A. ( 1989 ) Towards an epidemiology of political violence in the Third World . Social Science and Medicine , 14 , 633 – 646 .[cambridge.org]
  • Epidemiologic findings in two generations of Cambodian refugees. Journal ofNervous Mental Disorders , 182 , 387–395. CrossRef Google Scholar Weiner, Z., Reich W, Herjanic, B., Jung, K. G., and Amado, H. (1987).[link.springer.com]
  • Epidemiology of trauma deaths: a reassessment. J Trauma, 38 (1995), pp. 185-193 [4] D.S. Kauvar, R. Lefering, C.E. Wade. Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations.[medintensiva.org]
  • Impact of hemorrhage on trauma outcome: An overview of epidemiology, clinical presentations, and therapeutic considerations. J Trauma 2006;60(6 suppl):S3-S11. Sauaia A, Moore FA, Moore EE, et al. Epidemiology of trauma deaths: A reassessment.[ahcmedia.com]
Sex distribution
Age distribution

Pathophysiology

  • Note that the 1:1:1 concept is mainly supported by the fact that it makes sense pathophysiologically and by retrospective and observational studies.[lifeinthefastlane.com]
  • In fact, acidosis seems to be more important for coagulopathy than the hypothermia ( Hoffman et al, 2004 ) Coagulopathy due to acidosis is the result of multiple pathophysiological processes: The main problem is impaired thrombin generation.[derangedphysiology.com]
  • Pathophysiology of early trauma-induced coagulopathy: emerging evidence hemodilution and coagulation factor depletion. J Trauma, 70 (2011), pp. 1401-1407 [6] J.C. Duchesne, N.E. McSwain, B.A. Cotton, J.P. Hunt, J. Dellavolpe, K. Lafaro, et al.[medintensiva.org]
  • "Pathophysiology of polytrauma". Injury. 36 (6): 691–709. doi : 10.1016/j.injury.2004.12.037. PMID 15910820. Retrieved 2012-07-20. a b c d Committee on Trauma, American College of Surgeons (2008).[en.wikipedia.org]

Prevention

  • Early recognition of major blood loss and effective action is necessary to prevent shock and its consequences. Massive transfusion may challenge local resources.[pennstate.pure.elsevier.com]
  • A level-one trauma center is, according to the American Trauma Society, a facility that is capable of providing total care for every aspect of injury – from prevention through rehab.[abc57.com]
  • Despite improvement in care, uncontrolled bleeding contributes to 30 to 40% of trauma related deaths and is a leading cause of potentially preventable early in-hospital deaths[6 – 9].[slideshare.net]
  • Journal of Preventive Psychiatry , 2 , 275–301. Google Scholar Danieli, Y. (1985). The treatment and prevention of long-term effects and intergenerational transmission of victimization: A lesson from holocaust survivors and their children. In C. R.[link.springer.com]
  • ) from binding to fibrin and by preventing plasmin degradation of platelet glycoprotein Ib receptors[ 100 , 101 ].[sjtrem.biomedcentral.com]

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