Abstract A 50-day-old female child presented with asymptomatic skin colored raised lesion on the dorsal aspect of the left wrist since the age of 10 days. [ncbi.nlm.nih.gov]

Asymptomatic solitary cutaneous mastocytoma: A rare presentation. Indian J Dermatol 2014; 59(6): 634. [10] Krishnan KR, Ownby DR. A solitary mastocytoma presenting with urticaria and angioedema in a 14-year-old boy. [eurekaselect.com]

She has no prior history of itching, flushing, fevers, fatigue, night sweats, weight loss or skin rashes. She had experienced diarrhea whenever she ate wheat, several years earlier, but this subsided once she eliminated gluten from her diet. [ncbi.nlm.nih.gov]

Prolidase deficiency is an inherited connective tissue disorder that has systemic sequelae, such as intractable skin ulceration, poor wound healing, recurrent infections, and intellectual impairment. [journals.lww.com]

Her bowel movements are normal and she has no abdominal cramping or reflux. Cutaneous examination of her right abdomen showed an 8 x 4 mm brown patch with irregular borders ( Figure 1 ). [ncbi.nlm.nih.gov]

If there is a Dariers sign and a strong clinical suspicion this presentation is specific enough that I do not think biopsy is mandatory. [ncbi.nlm.nih.gov]

Symptoms may be localized to include pruritus or blistering of the lesion or generalized with flushing and rarely urticaria. [ncbi.nlm.nih.gov]

A 6-month old with total body flushing and a macular-papular lesion. Pediatr Emerg Care 2007; 23(5): 321-3. [23] Horny HP, Sotlar K, Valent P. Mastocytosis: State of the art. Pathobiology 2007; 74(2): 121-32. [24] Bourji L, Kurban M, Abbas O. [eurekaselect.com]

Results: Typically, a solitary cutaneous mastocytoma presents as an indurated, erythematous, yellow- brown or reddish-brown macule, papule, plaque or nodule, usually measuring up to 5 cm in diameter. [eurekaselect.com]

[…] cutaneous mastocytosis.[ 2 ] On an average, 10-15% of all patients with cutaneous mastocytosis have a solitary mastocytoma.[ 3 ] The majority of mastocytomas present during infancy, typically by 3 months of age, as a single indurated, red -brown macule, papule [ncbi.nlm.nih.gov]

These immunomodulators offer advantages over corticosteroids in terms of a more selective action, no associated systemic side-effects, and the absence of associated skin atrophy, depigmentation and telangiectasia. [ncbi.nlm.nih.gov]

She has no prior history of itching, flushing, fevers, fatigue, night sweats, weight loss or skin rashes. She had experienced diarrhea whenever she ate wheat, several years earlier, but this subsided once she eliminated gluten from her diet. [ncbi.nlm.nih.gov]