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Maternal Infection


Presentation

  • The present study reveals a high rate of acquiring filarial infection by the children born to infected mother than uninfected mothers even though Mf rate has come down to 1% after implementation of ten rounds of MDA.[ncbi.nlm.nih.gov]
  • Hence, in the present article, we focus on the potential for prevention of schizophrenia by control of infection, using these 3 categories of infection as examples.[ncbi.nlm.nih.gov]
  • A 3-month-old female baby presented with fever, jaundice, vomiting and stopping breast-feeding. Physical examination revealed mild respiratory distress, hepatosplenomegaly, microcephaly and growth retardation.[ncbi.nlm.nih.gov]
  • The higher rate of nosocomial infections with the Joel-Cohen incision was due to a greater proportion of patients presenting risk factors (i.e., emergency delivery, primary cesarean, blood loss or 800 mL, no manual removal of the placenta and no uterine[ncbi.nlm.nih.gov]
  • Screening for parvovirus B19 presents a greater concern because it meets most of the features of a screening test (Wilson’s criteria) endorsed by the WHO.[ncbi.nlm.nih.gov]
Developmental Disabilities
  • Abstract Congenital cytomegalovirus (CMV) infection is a leading cause of developmental disabilities.[ncbi.nlm.nih.gov]
  • Toro-Rivera, Division of Congenital and Developmental Disorders, National Center on Birth Defects and Developmental Disabilities, CDC; Joel M.[cdc.gov]
Colic
  • Data on routine surveillance variables, operative duration, and three additional variables (manual removal of the placenta, uterine exteriorization, and/or cleaning of the parieto-colic gutter) were collected.[ncbi.nlm.nih.gov]
Periodontitis
  • In the current study we present measures of maternal periodontal infection using whole chromosomal DNA probes to identify 15 periodontal organisms within maternal periodontal plaque sampled at delivery.[ncbi.nlm.nih.gov]
  • Urinary tract infection and periodontal disease during pregnancy are associated with an increased risk of preeclampsia.[ncbi.nlm.nih.gov]
  • Maternal oral infection such as clinical periodontal disease has also been identified as a risk factor for preterm birth, and pilot data suggest that oral treatment interventions undertaken during pregnancy may reduce preterm birth risk.[ncbi.nlm.nih.gov]
  • Cota LOM, Guimarães AN, Costa JE, Lorentz TCM, Costa FO (2006) Association between maternal periodontitis and an increased risk of preeclampsia. Journal of periodontology 77: 2063–2069 View Article Google Scholar 9.[journals.plos.org]
Suggestibility
  • Abstract Accumulating evidence suggests that maternal infection is a risk factor for schizophrenia.[ncbi.nlm.nih.gov]
  • OBJECTIVE: Epidemiological data have suggested maternal infection and fever to be associated with increased risk of autism spectrum disorder (ASD).[ncbi.nlm.nih.gov]
  • Maternal oral infection such as clinical periodontal disease has also been identified as a risk factor for preterm birth, and pilot data suggest that oral treatment interventions undertaken during pregnancy may reduce preterm birth risk.[ncbi.nlm.nih.gov]
  • CONCLUSIONS: Our results suggest that maternal infection is a risk factor for CP in both term and preterm infants.[ncbi.nlm.nih.gov]
  • Abstract Exposure to prenatal infection has been suggested to cause deficiencies in fetal neurodevelopment. In this study we included all children born in Denmark from 1980, through 2005.[ncbi.nlm.nih.gov]
Neonatal Seizures
  • Among children with CP, those born to infected women were more often hypotensive, needed intubation, had neonatal seizures, and received a clinical diagnosis of hypoxic-ischemic encephalopathy.[ncbi.nlm.nih.gov]

Workup

Mycoplasma Hominis
  • Individual studies did not find a relationship between herpes simplex virus type 2, bacterial vaginosis, and Mycoplasma hominis and preeclampsia.[ncbi.nlm.nih.gov]

Treatment

  • Author information 1 State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University,[ncbi.nlm.nih.gov]
  • Maternal reproductive infections such as bacterial vaginosis pose increased risk for preterm birth, although treatment of bacterial vaginosis has not proven to be universally effective in preterm birth prevention.[ncbi.nlm.nih.gov]
  • There were 27 cases of pulmonary edema, 16 of which (59.3%) were associated with treatment of preterm labor.[ncbi.nlm.nih.gov]
  • Treatment strategies for protection of at-risk mothers are limited to a narrow range of vaccines, which do not cover the bulk of the common pathogens most frequently encountered.[ncbi.nlm.nih.gov]
  • High-quality studies, particularly from settings with high neonatal mortality, are needed to determine whether targeting treatment of maternal infections or colonization, and/or prophylactic antibiotic treatment of newborns of high risk mothers, may prevent[ncbi.nlm.nih.gov]

Prognosis

  • BACKGROUND: Scarce data exist about screening, diagnosis and prognosis of non-primary Cytomegalovirus (CMV) during pregnancy.[ncbi.nlm.nih.gov]

Etiology

  • “This provides an important etiologic clue as to the origins of autism.” The link holds up regardless of whether the infection was bacterial, viral or caused by other or unknown pathogens.[spectrumnews.org]
  • The present study adds to the growing body of evidence, encompassing both animal and human studies, that supports possible immune-mediated mechanisms underlying the etiology of ASD.[journals.elsevier.com]
  • Many of the etiologic agents can be cultured from suitable specimens under proper conditions.[glowm.com]
  • […] due to the underlying etiology.[icd10data.com]
  • Serologic evidence of prenatal influenza in the etiology of schizophrenia. Archives of General Psychiatry 61, 774 – 780. Brown, AS, Cohen, P, Harkavy-Friedman, J, Babulas, V, Malaspina, D, Gorman, JM, Susser, ES ( 2001 ). A.E.[cambridge.org]

Epidemiology

  • Prospective epidemiological studies indicate that maternal influenza, toxoplasmosis, and genital/reproductive infection are associated with this disorder in offspring.[ncbi.nlm.nih.gov]
  • Abstract Epidemiological data indicate that maternal filarial infection might be associated with increased susceptibility to filarial infection in offspring.[ncbi.nlm.nih.gov]
  • OBJECTIVE: Epidemiological data have suggested maternal infection and fever to be associated with increased risk of autism spectrum disorder (ASD).[ncbi.nlm.nih.gov]
  • Background: The design of diagnostic and preventive strategies have been prevented by gaps in knowledge of the epidemiology of congenital cytomegalovirus (cCMV) with the type of maternal infection as well as the lack of large-scale neonatal screening[ncbi.nlm.nih.gov]
  • And epidemiological studies have found a link between altered levels of immune molecules in pregnant women and autism in their children 4, 5.[spectrumnews.org]
Sex distribution
Age distribution

Pathophysiology

  • Mechanisms of disease: glucocorticoids, their placental metabolism and fetal ‘programming’ of adult pathophysiology. Nature Clinical Practice. Endocrinology and Metabolism 3, 479 – 488.[cambridge.org]
  • Asian flu pandemic reported a mortality rate of approximately 50% among infected pregnant women. [21] During the 2009 H1N1 pandemic, pregnant women accounted for 5% of all deaths and were more likely to be hospitalized than the general population. [22] Pathophysiology[emedicine.medscape.com]
  • Br Med J 314 : 404–408 8 Gomez R, Ghezzi F, Romero R, Munoz H, Tolosa J, Rojas I 1995 Premature labor and intra-amniotic infection: clinical aspects and role of the cytokines in diagnosis and pathophysiology.[nature.com]

Prevention

  • Background: The design of diagnostic and preventive strategies have been prevented by gaps in knowledge of the epidemiology of congenital cytomegalovirus (cCMV) with the type of maternal infection as well as the lack of large-scale neonatal screening[ncbi.nlm.nih.gov]
  • Maternal reproductive infections such as bacterial vaginosis pose increased risk for preterm birth, although treatment of bacterial vaginosis has not proven to be universally effective in preterm birth prevention.[ncbi.nlm.nih.gov]
  • Effective prevention strategies need to be developed for both primary and non-primary maternal infections.[ncbi.nlm.nih.gov]
  • Prevention is better than cure 99% of deaths from puerperal sepsis in low and middle income countries are preventable with simple, low cost solutions such as healthcare provider hand washing at the time of delivery.[abdn.ac.uk]
  • Hence, in the present article, we focus on the potential for prevention of schizophrenia by control of infection, using these 3 categories of infection as examples.[ncbi.nlm.nih.gov]

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