[…] diethylcarbamazine in onchocerciasis, most commonly an intensely pruritic rash, but sometimes also systemic manifestations such as fever, malaise, lymph node swelling, eosinophilia, arthralgias, tachycardia, and hypotension; if numerous microfilariae are present [medicine.academic.ru]

A generalized urticarial rash was present covering his arms, legs and trunk. He had bulbar and palpebral conjunctival injection and angioedema of his face, with mild swelling of his lower extremities and penis. [journals.lww.com]

This presents acutely with fluctuating focal neurological signs and meningitis, with eosinophils in peripheral blood and cerebrospinal fluid. [europeanmedical.info]

• Fever

  Clinical findings Intense pruritic rash, fever, malaise, lymphadenopathy, eosinophilia, arthralgia, tachycardia, hypotension, oedema, abdominal pain. Mazzotti, Luigi, Mexican parasitologist, 1900-1971. [medical-dictionary.thefreedictionary.com]

  The patient was hospitalized with fever, urticaria, abdominal pain and angioedema. Twelve hours after treatment with intravenous methylprednisolone he had complete resolution of his symptoms. [ncbi.nlm.nih.gov]

  Even so, nearly one-fourth of patients treated with ivermectin develop isolated fever or pruritis without the remaining constellation of symptoms. [journals.lww.com]

• Camping

  CASE REPORT A 13-year-old Liberian child arrived in the United States with his mother and 3 siblings after living in a refugee camp in Guinea for 3 years. On arrival, the patient was clinically well and had a normal physical examination. [journals.lww.com]

  His history is also significant for the consumption of partially cooked fish during a camping trip 6 months previously. A physical examination reveals a blood pressure of 140/60 mm Hg, pulse of 72 beats/min, and a respiratory rate of 16 breaths/min. [accesspharmacy.mhmedical.com]

• Respiratory Distress

  *Mazzotti reaction* Reaction to proteins released by dying onchocerca, including fevers, rashes, ocular damage, joint and muscle pain, and lymphangitis as well as hypotension, pyrexia, respiratory distress, and prostration. [quizmed.blogspot.com]

  General reaction: hypotension, orthostatic, collapse, respiratory distress, vertigo, fever, arthralgia, myalgia, and headache have been described. These manifestations may be intense and persist for several days. [healthician.org]

• Tachycardia

  Clinical findings Intense pruritic rash, fever, malaise, lymphadenopathy, eosinophilia, arthralgia, tachycardia, hypotension, oedema, abdominal pain. Mazzotti, Luigi, Mexican parasitologist, 1900-1971. [medical-dictionary.thefreedictionary.com]

  Mazzotti reactions can be life-threatening, and are characterized by fever, urticaria, swollen and tender lymph nodes, tachycardia, hypotension, arthralgias, oedema, and ab... Found on Mazzotti reaction Synonym for Mazzotti test ... [encyclo.co.uk]

  Abstract Dear Editor, The Mazzotti reaction, originally described by Mazzotti (1948), is a complex of symptoms characterized by fever/chills, swollen and tender lymph nodes (lymphadenitis), headache, myalgia, arthralgia, tachycardia, hypotension/shock [deepdyve.com]

• Conjunctival Injection

  He had bulbar and palpebral conjunctival injection and angioedema of his face, with mild swelling of his lower extremities and penis. [journals.lww.com]

• Pruritus

  Skin manifestations include pruritus, and papules, edema, wheal, vesicles, pustules as primary skin lesions and scales, excoriation, erosion, ulcer and crusts as secondary skin lesions. [deepdyve.com]

  Hypotension, fever, adenitis and pruritus were all correlated with infection intensity in these patients while… CONTINUE READING [semanticscholar.org]

  The drug patch is placed on the skin, and if the patient is infected with the microfilaria of O. volvulus, localized pruritus and urticaria are seen at the application site. [en.wikipedia.org]

  Hypotension, fever, adenitis and pruritus were all correlated with infection intensity in these patients while arthralgia and tachycardia were not. [ncbi.nlm.nih.gov]

• Angioedema

  The patient was hospitalized with fever, urticaria, abdominal pain and angioedema. Twelve hours after treatment with intravenous methylprednisolone he had complete resolution of his symptoms. [ncbi.nlm.nih.gov]

  He had bulbar and palpebral conjunctival injection and angioedema of his face, with mild swelling of his lower extremities and penis. [journals.lww.com]

• Skin Patch

  The phenomenon is so common when DEC is used for the treatment of onchocerciasis that this drug is the basis of a skin patch test used to confirm that diagnosis. [en.wikipedia.org]

  patch test used to confirm that diagnosis. [journals.lww.com]

• Pruritic Rash

  Clinical findings Intense pruritic rash, fever, malaise, lymphadenopathy, eosinophilia, arthralgia, tachycardia, hypotension, oedema, abdominal pain. Mazzotti, Luigi, Mexican parasitologist, 1900-1971. [medical-dictionary.thefreedictionary.com]

  Mazzotti reaction the set of adverse reactions, which may be severe or rarely life-threatening, that accompany the administration of diethylcarbamazine in onchocerciasis, most commonly an intensely pruritic rash, but sometimes also systemic manifestations [medicine.academic.ru]

  Look at other dictionaries: Mazzotti reaction — the set of adverse reactions, which may be severe or rarely life threatening, that accompany the administration of diethylcarbamazine in onchocerciasis, most commonly an intensely pruritic rash, but sometimes [enacademic.com]

• Arthralgia

  Clinical findings Intense pruritic rash, fever, malaise, lymphadenopathy, eosinophilia, arthralgia, tachycardia, hypotension, oedema, abdominal pain. Mazzotti, Luigi, Mexican parasitologist, 1900-1971. [medical-dictionary.thefreedictionary.com]

  Mazzotti reactions can be life-threatening, and are characterized by fever, urticaria, swollen and tender lymph nodes, tachycardia, hypotension, arthralgias, oedema, and ab... Found on Mazzotti reaction Synonym for Mazzotti test ... [encyclo.co.uk]

  Abstract Dear Editor, The Mazzotti reaction, originally described by Mazzotti (1948), is a complex of symptoms characterized by fever/chills, swollen and tender lymph nodes (lymphadenitis), headache, myalgia, arthralgia, tachycardia, hypotension/shock [deepdyve.com]

• Headache

  Abstract Dear Editor, The Mazzotti reaction, originally described by Mazzotti (1948), is a complex of symptoms characterized by fever/chills, swollen and tender lymph nodes (lymphadenitis), headache, myalgia, arthralgia, tachycardia, hypotension/shock [deepdyve.com]

  General reaction: hypotension, orthostatic, collapse, respiratory distress, vertigo, fever, arthralgia, myalgia, and headache have been described. These manifestations may be intense and persist for several days. [healthician.org]

  Abdominal discomfort, particularly pain and nausea, diarrhea, headache, dizziness, and drowsiness may occur shortly after taking praziquantel; these direct effects are transient and dose related. [slideshare.net]

  Drug-related headache and myalgia occurred in [web.stanford.edu]

This decrease was followed by a marked eosinophilia developing over the remaining 7 days of treatment and 14 days of follow-up. [ncbi.nlm.nih.gov]

Twelve hours after treatment with intravenous methylprednisolone he had complete resolution of his symptoms. [doi.org]

Coadministration of albendazole is also recommended for presumptive treatment of other intestinal parasites. [journals.lww.com]

PMID: 6760823 Prognosis Awadzi K, Opoku NO, Addy ET, Quartey BT Trop Med Parasitol 1995 Jun;46(2):131-7. PMID: 8525285 Ackerman SJ, Kephart GM, Francis H, Awadzi K, Gleich GJ, Ottesen EA J Immunol 1990 May 15;144(10):3961-9. [ncbi.nlm.nih.gov]

Reactive angioendotheliomatosis has a good prognosis and usually regresses when the underlying disease, if discovered, is successfully treated. The disease sometimes regresses spontaneously. The prognosis depends on the underlying cause. [emedicine.medscape.com]

Etiology Trop Med Parasitol 1995 Jun;46(2):131-7. PMID: 8525285 Duke BO Acta Leiden 1990;59(1-2):9-24. PMID: 2198761 Büttner DW, von Laer G, Mannweiler E, Büttner M Tropenmed Parasitol 1982 Dec;33(4):201-12. [ncbi.nlm.nih.gov]

[…] visitors to endemic areas Requires exposure in endemic area for at least a few months Age: usually occurs in 20-40 y/o Sex: 80% of cases are males Race: Indians are most susceptible Possible relationship to Tropical Myocardial Fibrosis (unclear though) Etiology [mdnxs.com]

Laboratory Diagnosis Pruritus is a common and complex problem in the tropics, and may be the result of many infectious and noninfectious etiologies. Skin snips and scrapings are commonly obtained whenever infection is considered. [isradiology.org]

The etiology and incidence of anaphylaxis in Rochester, Minnesota: a report from the Rochester Epidemiology Project. J Allergy Clin Immunol 2008; 122: 1161–1165 PubMedCentral PubMed CrossRef Google Scholar 14. [doi.org]

Etiology Different triggers (eg, subacute bacterial endocarditis; circulating immune complexes; fibrin; cholesterol emboli; viruses, such as hepatitis C; atriovenous fistula [17] ; atherosclerotic emboli; trauma; metal implants [18] ; drugs such as trabectedin [emedicine.medscape.com]

International classification of ultrasound images in cystic echinococcosis for application in clinical and field epidemiological settings. Acta Trop 2003;85:253–261. [doi.org]

International classification of ultrasound images in cystic echinococcosis for application in clinical and field epidemiological settings. Acta Trop. 2003; 85 :253–261. [ PubMed ] [ Google Scholar ] [ncbi.nlm.nih.gov]

However, the cost is justifiable only when epidemiological data indicate that more than 5% of the population is infected. Simple diagnostic blood tests can be used to estimate the prevalence of microfilaraemia. [apps.who.int]

Epidemiology Most common in Southeast Asia, India, South Pacific Africa, South America (but cases have occurred in North American and European visitors to endemic areas Requires exposure in endemic area for at least a few months Age: usually occurs in [mdnxs.com]

They also address the consequences of drug interactions and the basic pathophysiology of central nervous system toxicity. [books.google.com]

Onchocerciasis River_Blindness -Pathophysiology (African_River_Blindness)#Pathophysiology Primary prevention Global preventative efforts are currently concentrated in population-based prophylactic treatment through programs such as the African Programme [flipper.diff.org]

Clinical observations on the pathophysiology and treatment of anaphylactic cardiovascular collapse. Anaesth Intensive Care 1986; 14: 17–21 PubMed Google Scholar 32. Pumphrey RS, Roberts IS. Postmortem findings after fatal anaphylactic reactions. [doi.org]

Pathophysiology The pathogenesis of reactive angioendotheliomatosis is still not fully elucidated. [emedicine.medscape.com]

Pretreatment with low-dose dexamethasone--prior to beginning DEC therapy--prevents the development of the Mazzotti reaction and greatly reduces the microfilaricidal activity. [ncbi.nlm.nih.gov]

Prevention and control An international onchocerciasis control programme is under way, using mass treatment of whole populations with ivermectin and doxycycline. Lymphatic filariasis is prevented by mosquito-control measures. [biocyclopedia.com]

These reactions may be attenuated or prevented by the institution of a progressive dosage and the addition of corticosteroids. [healthician.org]