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Measles Pneumonia


Presentation

  • Two weeks later the child presented with measles giant cell pneumonia diagnosed on open lung biopsy. Ribavirin therapy was again successful. The role of ribavirin in the treatment of measles in immunocompromised children is discussed.[ncbi.nlm.nih.gov]
Fever
  • In the present paper, we describe a 27-yr-old male who developed fever, skin rash typical of measles, and diffuse pulmonary infiltrates associated with respiratory failure.[ncbi.nlm.nih.gov]
  • , trench fever, human erlichiosis; and more.[books.google.com]
  • Other symptoms include Fever Cough Runny nose Conjunctivitis (pink eye) Feeling achy and run down Tiny white spots inside the mouth Sometimes measles can lead to serious problems.[icdlist.com]
  • The fever and other measles symptoms will recede and you — or your child should begin to feel better.[healthline.com]
Multiple Organ Dysfunction Syndrome
  • The clinical characteristics of complications such as hypoxemia, acute respiratory distress syndrome (ARDS), sepsis, pneumothorax, multiple organ dysfunction syndrome (MODS), and intracranial infection were retrospectively analyzed; in addition, the death[ncbi.nlm.nih.gov]
Hypoxemia
  • RESULTS: The 58 infants experienced the following: hypoxemia, 100%; ARDS, 21%; sepsis, 34%; pneumothorax, 14%; MODS, 16%; and intracranial infection, 9%.[ncbi.nlm.nih.gov]
  • Results: The 58 infants experienced the following: hypoxemia, 100%; ARDS, 21%; sepsis, 34%; pneumothorax, 14%; MODS, 16%; and intracranial infection, 9%.[jidc.org]
Pathologist
  • Consultant pathologist Dr Maurizio Brotto told the inquest that 5ft 8ins tall Mr Colfer-Williams was "very underweight" at just 7st 7lbs.[bbc.com]
Collapse
  • During analyses, we collapsed the last 2 categories of anthropometric status so that the reference group would comprise those children with weight-for-age z scores 1.0 SD.[ajcn.nutrition.org]
Aspiration
  • Bacterial superinfection as documented by transtracheal aspiration occurred in 35 cases (30.3 percent) and was caused by Hemophilus influenzae (18), Hemophilus parainfluenzae (two), Neisseria meningitidis (nine), Streptococcus pneumoniae (three), Streptococcus[ncbi.nlm.nih.gov]
  • Other pathogens were identified by blood culture, virus isolation or antigen detection from nasopharyngeal aspirate and antibody determination from serum. Of 182 MAP cases 162 (89%) had clinically typical measles.[journals.lww.com]
  • NIH: National Heart, Lung, and Blood Institute Aspiration pneumonia (Medical Encyclopedia) Atypical pneumonia (Medical Encyclopedia) Hospital-acquired pneumonia (Medical Encyclopedia) Mycoplasma pneumonia (Medical Encyclopedia) Pneumonia (Medical Encyclopedia[icdlist.com]
Respiratory Distress
  • Abstract We report a 21-day-old preterm infant who had severe respiratory distress of 6 days' duration and whose lungs revealed a giant cell pneumonia at necropsy.[ncbi.nlm.nih.gov]
  • The clinical characteristics of complications such as hypoxemia, acute respiratory distress syndrome (ARDS), sepsis, pneumothorax, multiple organ dysfunction syndrome (MODS), and intracranial infection were retrospectively analyzed; in addition, the death[jidc.org]
Cyanosis
  • Cyanosis and a respiratory rate of 60/min predict a greater risk of dying.[journals.lww.com]
Vascular Disease
  • Hammar Springer Science & Business Media, 2013/06/29 - 1656 ページ The first edition of Pulmonary Pathology was dedicated to Vascular Diseases. Vasculitis is so complex as to con two giants in the field, Drs.[books.google.com]
Exanthema
  • […] their children and importation ( Cleve Clin J Med 2010;77:207 ) Highly infectious, affecting up to 90% of individuals in nonimmune populations Also occurs in adults ( MMWR Morb Mortal Wkly Rep 2011;60:666 ) Pneumonia is serious complication of childhood exanthema[pathologyoutlines.com]
  • The diagnosis of the invasion of measles from a study of the exanthema as it appears on the buccal mucous membrane By Henry Koplik, M.D. Reproduced from Arch. Paed. 13, 918–922 (1886). Rev. Med. Virol. 7, 71–74 (1997). 54. Singh, B. K. et al.[nature.com]
Grunting
  • Research of Post Measles Pneumonia has been linked to Pneumonia, Measles, Grunting Respiration, Tachypnea, Sequelae Aspects.[novusbio.com]

Workup

  • Complicated and possibly hazardous workups can be avoided by awareness of this disease.[ncbi.nlm.nih.gov]
Pulmonary Infiltrate
  • In the present paper, we describe a 27-yr-old male who developed fever, skin rash typical of measles, and diffuse pulmonary infiltrates associated with respiratory failure.[ncbi.nlm.nih.gov]

Treatment

  • The role of ribavirin in the treatment of measles in immunocompromised children is discussed.[ncbi.nlm.nih.gov]
  • Most of these lives could be saved by expanding low-cost prevention and treatment measures.[unicef.org]
  • There is no treatment for measles, but the measles-mumps-rubella (MMR) vaccine can prevent it. "German measles", also known as rubella, is a completely different illness.[icdlist.com]

Prognosis

  • Prognosis (cont.) Deaths are primarily due to pneumonia or secondary bacterial infections.[slideshare.net]
  • Prognosis Most healthy people recover completely from measles. About 3% of adults with measles develop symptoms of pneumonia severe enough to require hospital treatment.[health.harvard.edu]

Etiology

  • Abuse of antibiotics in China and its potential interference in determining the etiology of pediatric bacterial diseases. Pediatr Infect Dis J. 1993;12:986–7. doi: 10.1097/00006454-199312000-00004.[bmcpediatr.biomedcentral.com]
  • Etiology Measles virus, the cause of measles, is an RNA virus of the genus Morbillivirus in the family Paramyxoviridae. Only one serotype is known 4. Epidemiology Measles is endemic throughout the world.[slideshare.net]

Epidemiology

  • Epidemiology Measles is endemic throughout the world. In the past, epidemics tended to occur irregularly, appearing in the spring in large cities at 2-4-yr intervals as new groups of susceptible children were exposed. 5. Epidemiology (Cont.)[slideshare.net]
  • , 200336, China (3) Department of Biostatistics, University of Michigan, Ann Arbor, 1415 Washington Heights, Ann Arbor, MI 48109, USA (4) Department of Epidemiology and Health Promotion, Public Health Service of Amsterdam, Amsterdam, the Netherlands ([bmcpediatr.biomedcentral.com]
  • All suspected cases should be confirmed, ideally by testing of oral fluid (saliva), but management will often have to be based on a clinical and epidemiological risk assessment of the likelihood of the case being true measles. 8.[gov.uk]
  • Global distribution of measles genotypes and measles molecular epidemiology. J. Infect. Dis. 204, S514–S523 (2011). 119. Greenwood, K. P., Hafiz, R., Ware, R. S. & Lambert, S. B.[nature.com]
  • Measles chapter of the Epidemiology and Prevention of Vaccine Preventable Diseases (Pink Book); CDC Measles: Questions and Answers; Immunization Action Coalition[everydayhealth.com]
Sex distribution
Age distribution

Pathophysiology

  • .); Mechanisms/pathophysiology (M.T. and R.L.d.S.); Diagnosis, screening and prevention (P.A.R. and R.L.d.S.); Management (K.M.T.); Quality of life (K.M.T.); Outlook (J.L.G.); Overview of Primer (P.A.R.).[nature.com]

Prevention

  • Prevention of measles pneumonia is clearly the preferred "treatment." Preventive healthcare is paramount in providing optimal care for children.[ncbi.nlm.nih.gov]
  • Preventing pneumonia is always better than treating it. Vaccines are available to prevent pneumococcal pneumonia and the flu. Other preventive measures include washing your hands frequently and not smoking.[icdlist.com]
  • Most of these lives could be saved by expanding low-cost prevention and treatment measures.[unicef.org]
  • According to a report released by UNICEF on Monday, most of these deaths are preventable. Pneumonia alone kills more children under five than any other disease.[ugandaradionetwork.com]

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