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Mediastinal Abscess
Mediastinum Abscess

Presentation

To our knowledge, no other such case has ever been reported and we present this unusual case herein, followed by a short review of the related literature. [ncbi.nlm.nih.gov]

Entire Body System

  • Pain

    Mediastinal widening was seen on the chest radiograph of a diabetic patient who presented with nonspecific symptoms of shortness of breath and abdominal pain of 3 days' duration. [ncbi.nlm.nih.gov]

  • Fever

    A 76-year-old man who had undergone tricuspid annuloplasty 13 years earlier was admitted to our hospital because of a high fever. Although he was treated with antibiotics for pneumonia, a mild fever persisted. [ncbi.nlm.nih.gov]

    This study reports a case of a young male with fever, dry cough, reduced appetite and weight loss for one month presenting radiologically as a mediastinal mass. [eurekaselect.com]

  • Swelling

    Injury to the hypopharynx or esophagus with child abuse as a possible etiology should be considered when an infant or young child presents with unexplained erythematous neck swelling, subcutaneous emphysema, pneumomediastinum and/or wide mediastinum. [ncbi.nlm.nih.gov]

    The swelling would have fluctuations and there would be no transillumination. [boneandspine.com]

    The present complaint is a painful swelling on the left side of the neck since one day. [radiologyassistant.nl]

    These signs can include fever, swelling of the floor of the mouth, swelling below the inferior border of the mandible, asymmetric bulging of the pharyngeal walls and trismus or pain out of proportion to the amount of swelling ( Table 1 ). [cda-adc.ca]

  • Surgical Procedure

    Currently, mediastinitis occurred mostly as a complication post cardiovascular or thoracic surgical procedures. Rarely, primary mediastinitis developed as a result of hematogenous spread. [ncbi.nlm.nih.gov]

    Before the availability of antibiotics, a typical abscess arose from complications after oral surgical procedures (ie, tonsillectomy ), resulting in aspiration of infected material into the lungs. [emedicine.medscape.com]

    Surgical procedures are required in selective patients for drainage or pulmonary resection. the treatment is divided according to the type of abscess acute or chronic if it's acute the treatment is a- antibiotics: if anaerobic -> metronidazole or clindamycin [en.wikipedia.org]

    Major risk factors include diabetes, obesity, vascular disease, prolonged surgical procedure and bilateral internal mammary artery harvest. [cancertherapyadvisor.com]

  • Disability

    Please enable JS and disable any ad blocker [rheumatologynetwork.com]

    Submissions are welcome from authors of all ethnicities, races, colours, religions, sexes, sexual orientations, gender identities, national origins, disabilities, ages, or other individual status. Submit your manuscript now! [giornalechirurgia.it]

    These are typically institutionalized individuals with severe intellectual disabilities or who are post-stroke. [pulmonologyadvisor.com]

Respiratoric

  • Aspiration

    After the stylet was removed, an aspiration vacuum syringe with a 3-way tap was used to apply negative pressure to the aspiration needle while needle was moved back and forth under direct EBUS visualization. [omicsonline.org]

    Keywords: Abscess, aspiration, bronchoscopy, compression, mediastinal, Mycobacterium tuberculosis. [eurekaselect.com]

    There are two forms of aspiration syndrome: large-volume aspiration, which is acutely symptomatic, and chronic, small-volume aspiration with slowly progressive complaints. [pulmonologyadvisor.com]

    The introduction of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) brought about significant advancement in the field of bronchoscopy. [ncbi.nlm.nih.gov]

  • Cough

    This study reports a case of a young male with fever, dry cough, reduced appetite and weight loss for one month presenting radiologically as a mediastinal mass. [eurekaselect.com]

    Cough, fever with shivering, and night sweats are often present. [en.wikipedia.org]

    Chronic Cough Azygo-esophageal recess Azygo-esophageal recess Bronchogenic Cysts Bronchogenic Cysts Anterior junction line Anterior junction line  Extends from thoracic inlet inferiorly and to the left  Extends from thoracic inlet inferiorly and to [learningradiology.com]

    We report the case of a 14-year-old boy, who presented with dry cough and progressively increasing breathlessness, and was found to have a cystic lesion in the posterior mediastinum. [lungindia.com]

  • Dyspnea

    A 46-year-old man, with a history of subaortic membranectomy, was admitted with a new onset fever and dyspnea. [ncbi.nlm.nih.gov]

    These symptoms include chest pain, cough, dyspnea, fever, and purulent sputum (, 10 ). [pubs.rsna.org]

    On hospital day 2, hoarseness, dyspnea, and rapid progression of swelling and erythema on whole neck area were observed. Neck CT with enhancement showed retropharyngeal fluid collection spreading to mediastinum ( Fig. 2A ). [e-sciencecentral.org]

    […] which air is present within the mediastinum. 1 Pneumomediastinum occurs more frequently in infants than in older children. 2 Affected pediatric patients typically present with a sensation of retrosternal fullness, dysphagia, sore throat, chest pain, or dyspnea [clinicalgate.com]

  • Hoarseness

    Presentation He was noted to be irritable with a hoarse voice and neck extension. He was noted to have high infection markers and was commenced on Ceftriaxone. He deteriorated over the next 24 h and his blood cultures were positive for S Aureus. [adc.bmj.com]

    For example in the cervical spine, the exudate collects behind prevertebral fascia & protrude forward as retropharyngeal abscess which may cause dysphagia, dysphonia, dyspnoea and/or hoarseness of voice Laterally, it may spread into the sternomastoid [boneandspine.com]

    On hospital day 2, hoarseness, dyspnea, and rapid progression of swelling and erythema on whole neck area were observed. Neck CT with enhancement showed retropharyngeal fluid collection spreading to mediastinum ( Fig. 2A ). [e-sciencecentral.org]

    The patient complained of hoarseness of his voice, numbness of his lower lip, dysphagia and marked trismus. He was pyrexic and tachycardic. [nature.com]

    The typical child presents with a muffled (not hoarse) voice, fever, drooling and stridor. The stridor is usually most pronounced on inspiration and the child tends to maintain an upright position with the neck extended. [utmb.edu]

  • Hemoptysis

    Despite antibiotic treatment, she had massive hemoptysis and eventually succumbed to the disease. [ncbi.nlm.nih.gov]

    Case Report A 26-year-old male who didn’t have any underlying diseases visited the emergency room at a university hospital with fever, pleuritic chest pain, and hemoptysis that began 2 days ago. [e-sciencecentral.org]

    Patients may also present with hemoptysis and pleuritic chest pain. Sputum may be purulent or blood-streaked and classically smells or tastes foul. Symptoms of abscess due to aerobic bacteria develop more acutely and resemble bacterial pneumonia. [merckmanuals.com]

    Half of patients report expectoration of putrid sputum that may or may not be associated with hemoptysis. These patients appear chronically ill and have fevers generally below 39°C. [pulmonologyadvisor.com]

Gastrointestinal

  • Dysphagia

    We reported here a case of tubercular mediastinal necrotic lymphadenopathy causing dysphagia. [omicsonline.org]

    Abstract Patients with advanced esophageal cancer may require intubation with a stent to relieve debilitating dysphagia. [ncbi.nlm.nih.gov]

    When the cyst is large, affected pediatric patients present with a slowly enlarging neck mass that may be associated with respiratory compromise, dysphagia, or vocal cord paralysis. [clinicalgate.com]

    Right Aortic Arch Right Aortic Arch 70 yo with dysphagia 70 yo with dysphagia Esophageal Carcinoma Esophageal Carcinoma Zenker Diverticulum Zenker Diverticulum Right paratracheal stripe   Extends from thoracic inlet to azygos vein   Widens out at [learningradiology.com]

Jaw & Teeth

  • Dental Caries

    caries 3 and have a mortality rate of 8-10%. 3,4 Anaerobic bacteria were responsible for the gas formation in the soft tissues. [cda-adc.ca]

Cardiovascular

  • Chest Pain

    A 22-year-old man, diagnosed 7 weeks before with pulmonary tuberculosis and started on antitubercular therapy, presented with non-exertional retrosternal chest pain since the past week. [ncbi.nlm.nih.gov]

    On the following day the fever subsided, chest pain decreased and he was kept on the same antibiotic while paracetamol was stopped. Twelve days later, the WBC started to decrease and his WBC was 4300/ μl. [jcdr.net]

    These symptoms include chest pain, cough, dyspnea, fever, and purulent sputum (, 10 ). [pubs.rsna.org]

  • Thrombosis

    548 623 Acute Pelvic Vein and Inferior Vena Cava Occlusion 552 624 Acute Mesenteric Vein Occlusion 554 625 Acute Venous Occlusion of the Upper Extremity 556 626 Acute Venous Occlusion of Arteriovenous Hemodialysis Access 557 627 Acute Cerebral Vein Thrombosis [books.google.com]

    and jugular vein (thrombosis) anterior compression and compromise of the airway inferior extension into the mediastinum resulting in mediastinitis systemic dissemination and development of sepsis Grisel syndrome Lemierre syndrome retropharyngeal cellulitis [radiopaedia.org]

    Sphenoid sinusitis can spread to cause cavernous sinus thrombosis, meningitis, temporal lobe abscess, and the superior fissure symdrome. [utmb.edu]

    Thrombosis of jugular vein Jugular vein thrombosis Thrombosis of the internal jugular vein is an under-diagnosed condition that may occur as a complication of head and neck infections, surgery, central venous access, and intravenous drug abuse. [radiologyassistant.nl]

  • Retrosternal Chest Pain

    A 22-year-old man, diagnosed 7 weeks before with pulmonary tuberculosis and started on antitubercular therapy, presented with non-exertional retrosternal chest pain since the past week. [ncbi.nlm.nih.gov]

    Retrosternal chest pain, usually described as pleuritic, may radiate to the neck or back. There may be a sensation of soreness or congestion in the neck if the condition is due to descending infection. [patient.info]

Skin

  • Erythema

    We do believe, however, that the intubation attempts contributed to the rapid development of edema and erythema of the neck by disrupting the cervical fascial planes. [anesthesiology.pubs.asahq.org]

    On hospital day 2, hoarseness, dyspnea, and rapid progression of swelling and erythema on whole neck area were observed. Neck CT with enhancement showed retropharyngeal fluid collection spreading to mediastinum ( Fig. 2A ). [e-sciencecentral.org]

    Oedema and/or erythema of the neck and face may be found. There may be crepitus of the skin of the chest and neck due to surgical emphysema. The mouth should be examined for evidence of pharyngeal infection or foreign bodies. [patient.info]

Psychiatrical

  • Suggestibility

    Analysis of the fluid obtained was suggestive of tuberculous aetiology. Steroids were not required. [ncbi.nlm.nih.gov]

    Uncommon but suggestive findings include amphoric breath sounds over the abscess cavity and clubbing of the fingers. [pulmonologyadvisor.com]

Face, Head & Neck

  • Neck Edema

    All clinicians evaluating a "sore throat" should consider neck edema or gas on neck radiograms as evidence of cervical abscess, and subsequent widening of the mediastinum on chest x-ray as an ominous sign suggesting mediastinal abscess. [ncbi.nlm.nih.gov]

    Cricothyroidotomy is usually not a good option with in patients with massive neck edema. [utmb.edu]

Workup

The workup should include finding the tubercular lesion. Routine blood works will show increased lymphocytes, raised ESR and CRP. Antigravity aspiration and study for tuberculous bacteria are initiated which include PCR and culture of the aspirate. [boneandspine.com]

Nonetheless, the practice of assigning a mediastinal mass to a specific mediastinal compartment is still useful because such a method enables one to formulate a manageable differential diagnosis and effectively direct further imaging workup, and it yields [clinicalgate.com]

Cardiac workup was done in view of exertional breathlessness. [jcor.in]

X-Ray

  • Mediastinal Mass

    Abstract Salmonella is a rare cause of a mediastinal infection. This report describes the 14-year natural history of a mediastinal mass with eventual abscess formation. [ncbi.nlm.nih.gov]

    This study reports a case of a young male with fever, dry cough, reduced appetite and weight loss for one month presenting radiologically as a mediastinal mass. [eurekaselect.com]

    Inspiratory and expiratory views of the chest demonstrate an ill-defined mediastinal opacity and hyperinflation of the right lung due to gas trapping. Loading images... Mediastinal mass with peripheral enhancement and central hypodensity. [radiopaedia.org]

    Mediastinal Masses Overview The mediastinum is the most common location of chest masses in the pediatric population. [clinicalgate.com]

    (a) Chest radiograph shows a large mediastinal mass. (b) Contrast-enhanced CT scan shows a low-attenuation mass (arrow) that extends to all mediastinal compartments. [pubs.rsna.org]

Serum

  • Neutrophilia

    Radiographs showed evidence of chronic periapical infection from the lower left first and second molars. ( Fig. 1 ) Laboratory investigations revealed leucocytosis with neutrophilia and a raised C-reactive protein. [nature.com]

    Total blood examination was normal except for neutrophilia (total count 9300, polymorphs 90%, and erythrocyte sedimentation rate 10 mm). [jcor.in]

    Acute abdominal symptoms, radiological finding of small bowel PI with massive PMVG, severe neutrophilia, and high serum lactate forced us to perform exploratory laparotomy, from which it was observed a diffuse band-like pneumatosis of all the small bowel [giornalechirurgia.it]

Treatment

There is a lack of consensus on the optimal treatment for this condition. [ncbi.nlm.nih.gov]

Prognosis

Mediastinal abscess is a rare but life-threatening disease with grave prognosis if not recognized in time. The diagnosis of this entity is hampered by its nonspecific presentation. [ncbi.nlm.nih.gov]

Prognosis of Lung Abscess How is Lung Abscess Treated? Lung Abscess References What is Lung Abscess A lung abscess is a localised infection within the lung. An abscess is a pus-containing cavity. [healthengine.com.au]

[ edit ] Most cases respond to antibiotics and prognosis is usually excellent unless there is a debilitating underlying condition. [en.wikipedia.org]

Prognosis Patients with mediastinitis, empyema and purulent pericaditis should be treated with broad spectrum antibiotics, supportive care and surgical drainage. The prognosis depends on the timeliness of surgical intervention and treatment. [cancertherapyadvisor.com]

Etiology

The diagnosis of primary gas-containing mediastinal abscess was established by the characteristic findings of computed tomography and exclusion of all the etiological possibilities. [ncbi.nlm.nih.gov]

Mediastinal Infection Chronic Fibrosing Mediastinitis Etiology: Chronic fibrosing mediastinitis, also known as sclerosing mediastinitis, is rare in the pediatric population. [clinicalgate.com]

Etiology [ edit ] An observational retrospective study of 17 patients diagnosed with DNM found that the infections most often originated from neck infections including tonsillar abscess, pharyngitis, and epiglottitis. [en.wikipedia.org]

Epidemiology

Epidemiology Mediastinitis is a relatively rare phenomenon in patients who have not undergone cardiothoracic surgery or another intervention. [patient.info]

We investigated the epidemiology of infections after lung transplantation and determined their impact on survival. [slideplayer.org]

Defilippi A, Silvestri M, Tacchella A et al (2008) Epidemiology and clinical features of Mycoplasma pneumoniae infection in children. Respir Med 102:1762–1768 Google Scholar 45. [link.springer.com]

Epidemiology Approximately 60,000 patients develop pleural infections in the United States each year. Between 40-60% of pneumonias will be associated with parapneumonic effusions. [cancertherapyadvisor.com]

Pathophysiology

We review the published literature regarding infective complications of EBUS-TBNA and propose possible pathophysiologies. These complications are likely to increase in frequency as the technique is more widely adopted. [ncbi.nlm.nih.gov]

Pathophysiology Empyema The potential space between the parietal pleura and visceral pleura normally contains small amounts of circulating, sterile fluid that can become infected by an adjacent pneumonia or bronchopleural fistula, or seeded by bacteremia [cancertherapyadvisor.com]

Prevention

HIV exposure and needle stick injury prevention for health worker. National workshop on prevention of needle stick injuries for health worker, November, 2003 2003: Ascaridiose biliopancreatique. Ann Chir France Cecum fistula after appendectomy. [eng.benhvienvietduc.org]

The pathophysiology of this severe complication, as well as its diagnosis, management, and prevention, is discussed, together with a review of the medical scientific literature. [ncbi.nlm.nih.gov]

Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the latest findings about new antimicrobial agents, gram-negative infections and their management, and recommendations for immunization [books.google.de]

After diagnosis, prompt removal is mandatory to prevent esophageal perforation and development of subsequent mediastinitis. [jtd.amegroups.com]

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