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Mediastinal Metastasis

Metastatic Neoplasm to the Mediastinum


Presentation

  • We report a case of an unusual initial presentation of follicular thyroid carcinoma on follow-up. A 52- year-old woman presented with a 12-month history of progressively enlarging mass in the anterior chest wall.[ncbi.nlm.nih.gov]
  • Educational points: Sclerosing hemangioma can present unusually increased lymph node enlargement with multiple lung nodules and also have positive PET uptakes. Sometimes, SH can present a feature of low grade malignant potency.[erj.ersjournals.com]
  • Generally, patients with RCC present with gross hematuria, flank pain and a palpable mass; however, these symptoms are not always present.[spandidos-publications.com]
Chest Discomfort
  • Thirteen years later, he consulted his primary physician regarding chest discomfort.[academic.oup.com]
Euthyroid
  • The patient was clinically euthyroid, with a normal thyroid gland on palpation and no adenopathies on physical examination.[elsevier.es]
Painful Cough
  • At least 90% of patients with these tumors experience: chest pain cough fever shortness of breath but these symptoms may not appear until the tumor has grown very large. LYMPHOMAS. These tumors account for 10-20% of anterior mediastinal tumors.[encyclopedia.com]
Pharyngitis
  • […] posterosuperior mediastinum ( Figs. 1 and 2 ) after the histological study reported the finding in an intraoperative biopsy of a cystic wall of fibrous tissue with thyroid follicles without atypia and associated lymphocyte infiltrate consistent with pharyngeal[elsevier.es]
Chest Pain
  • On the day of admission, the patient experienced an abrupt onset of dyspnea and left pleuritic chest pain.[kjim.org]
  • Others cough or experience chest pain. THYROID TUMORS. Most mediastinal thyroid tumors grow out of goiters and occur in women between the ages of 50 and 60. About 75% of these tumors extend to the windpipe (trachea). The rest extend behind it.[encyclopedia.com]
  • When symptoms occur, however, they often result from compression of the surrounding structures and may include: Cough Shortness of breath Chest pain Fever Chills Night sweats Coughing up blood Hoarseness Unexplained weight loss Lymphadenopathy (swollen[bmc.org]
  • Symptoms can include: cough shortness of breath chest pain fever/chills night sweats coughing up blood unexplained weight loss swollen lymph nodes respiratory blockage hoarseness If you have symptoms of a mediastinal tumor, your doctor will order additional[healthline.com]
  • Four months before admission, the patient started to present with mild diffuse abdominal pain, hyporexia, increased abdominal volume, dry cough, anterior chest pain, and loss of 4 kg in the last mouth.[hrjournal.net]
Testicular Mass
  • Physical examination was normal except for a left testicular mass of approximate size 5 5 4 cm, which was smooth, hard and did not transilluminate. No induration of spermatic cord, no gynecomastia and no palpable lymphadenopathy was found.[sjkdt.org]

Workup

Lymphocytic Infiltrate
  • infiltrate consistent with pharyngeal pouch abnormalities.[elsevier.es]

Treatment

  • OBJECTIVE: To assess the anterior mediastinal mass in recurrent testicular cancer, with relation to thymic hyperplasia after treatment.[ncbi.nlm.nih.gov]
  • Multidisciplinary contributions on medical treatment, radiation oncology, and surgery and anesthesia are included. Highlights include new material on minimally invasive procedures and thoroughly updated diagnostic and treatment information.[books.google.com]

Prognosis

  • The prognosis of patients with superior mediastinal metastasis dissected by sternotomy was significantly poorer.[ncbi.nlm.nih.gov]

Etiology

  • Pulmonary intravascular bronchoalveolar tumor (IVBAT) also recognized as pulmonary epithelioid hemangioendothelioma, is a rare malignant vascular tumor of unknown etiology.[ncbi.nlm.nih.gov]
  • Some radiologists make a point of differentiating between reactive nodal enlargement and pathological nodal enlargement, reserving lymphadenopathy for the latter etiologies only.[radiopaedia.org]
  • Mediastinal lymph node tuberculosis is one of the most common etiologies for radiologically necrotic mediastinal lymphadenopathy, especially in highly tuberculosis (TB)-prevalent settings.[lungindia.com]
  • Multiple enhancing lesions in multiple compartments Enhancing masses The differential diagnosis of enhancing mediastinal masses is: Hyperenhancing lymph nodes Thyroid tissue Paragangliomas Hemangiomas Vascular Etiologies On the left multiple enhancing[radiologyassistant.nl]

Epidemiology

  • According to an article recently published in the American Journal of Epidemiology, use of some residential pesticides may increase the risk of breast cancer.[news.cancerconnect.com]
  • Thoracic Surgeons IASLC International Association for the Study of Lung Cancer ITMIG International Thymic Malignancies Interest Group JART Japanese Association for Research on the Thymus NCCN National Comprehensive Cancer Network SEER Surveillance, Epidemiology[haigan.gr.jp]
Sex distribution
Age distribution

Prevention

  • Baozhong Zhang, Lujun Zhao, Zhiyong Yuan, Qingsong Pang, Ping Wang Department of Radiotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy[dovepress.com]
  • EBUS-TBNA helped in establishing a correct diagnosis of metastatic squamous cell carcinoma in our patient, thus preventing this patient from a delay in receiving further appropriate treatment for the same and prevented inappropriate administration of[lungindia.com]
  • EBRT is used to improve local control and prevent relapse, especially in patients with gross extrathyroidal extension, or local failure despite adequate surgery and appropriate RAI.[thyroid.org]
  • During laparotomy, a partial gastrectomy was performed to prevent tumor bleeding with achieving negative margin.[omicsonline.org]

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