Presentation
On presentation, he had right sided wheezes on physical exam. [pulmonarychronicles.com]
Major changes have recently occurred in the clinical presentation, diagnosis, and management of primary lesions of the mediastinum. [ncbi.nlm.nih.gov]
As many as 97% of our patients were symptomatic at presentation. [thoracicmedicine.org]
Hypogammaglobulinaemia is present in 2-5% of patients with thymoma A. [ieo.it]
The other three presented with dyspnoea. Blood tests were normal in all the patients. [academic.oup.com]
Entire Body System
- Weight Gain
This is primarily a clinical diagnosis characterized by hepatomegaly or right upper quadrant pain, jaundice, ascites, and unexplained weight gain. [intranet.tdmu.edu.ua]
Respiratoric
- Mediastinal Disease
Mediastinal diseases are conditions that arise from tissues in this cavity. [utswmedicine.org]
Thyroid mass mediastinal – a benign growth such as a goiter. These masses may develop into cancer. Middle mediastinal tumors include: Bronchogenic cysts - a disease in the respiratory system. Lymphadenopathy mediastinal - disease in the lymph nodes. [cedars-sinai.edu]
In 1888, Hare 1 collected 520 cases of mediastinal disease, over 50 per cent of which were due to tumors, mostly of the malignant type. [jamanetwork.com]
Many mediastinal diseases are treated clinically, such as lymphomas, or are clearly not resectable, such as metastatic neoplasias; therefore, the hystopathological diagnosis is obviously essential for these patients. [scielo.br]
Gastrointestinal
- Dysphagia
Respiratory symptoms and dysphagia can occur due to bronchial and esophageal obstruction respectively. [learn.pediatrics.ubc.ca]
Symptoms Chest pain Dyspnea Cough Fever Weight loss Fatigue Dysphagia Night sweats 16. [slideshare.net]
Lesions in the posterior mediastinum may encroach on the esophagus, causing dysphagia or odynophagia. [msdmanuals.com]
Thirty to fifty percent of those with thymomas also have myasthenia gravis so symptoms of weakness, fatigue, ptosis, diplopia and dysphagia can be reported. [cancertherapyadvisor.com]
Face, Head & Neck
- Head and Neck Swelling
If arising from the muscles of head and neck, an asymptomatic firm swelling is apparent. Orbital tumors often cause pain and swelling about the eye with proptosis and diplopia. [intranet.tdmu.edu.ua]
Workup
There were 144 cases having abnormal mediastinal lesions detected on initial diagnostic workup on the chest radiology. [lungindia.com]
Follow-up of the patient includes clinical examination, chest radiographs, computed tomography, and metastatic workup every 6 to 12 months [10] and should be monitored closely for 10 years or less after primary diagnosis. > Conclusions This case report [cancerjournal.net]
In many cases, no further workup is needed for diagnosis. Characterization of the mass on the CT scan is based on specific attenuation of water, air, fat, calcium, soft tissue, and vascular structures. [ncbi.nlm.nih.gov]
X-Ray
- Mediastinal Mass
The variation in these imaging findings played an important role in the differential diagnosis of this uncommon mediastinal mass. [ncbi.nlm.nih.gov]
Here we describe two patients with neoplastic anterior mediastinal masses associated with GD, illustrating that this may not be safe approach to all patients with anterior mediastinal masses and GD. [thyroidresearchjournal.biomedcentral.com]
Technetium-99m methylene diphosphonate bone scintigraphy showed intense uptake in both the T1 and marginal parts of the mediastinal mass. [ajnr.org]
Mediastinal mass; Retrieve from: http://radiopaedia.org/articles/mediastinal-mass 5. Richard W. [cancerwall.com]
Many mediastinal masses are asymptomatic and are an incidental finding on chest radiographs. Over 50% of pediatric mediastinal masses are malignant and as a result need to be investigated thoroughly. [learn.pediatrics.ubc.ca]
- Superior Mediastinal Mass
[…] abnormalities The superior mediastinal mass present above the thoracic plane (upper side): Neoplastic and non-neoplastic pathology. [cancerwall.com]
- Esophageal Motility Disorder
Motility Disorders 1887 Thomas W Shields 2069 Barretts Esophagus 1925 166 Radiographic Computed Tomographic 2079 Cardial Incompetence and Associated Mediastinum 2103 Katherine A Barsness and Marleta Reynolds 168 Mediastinal Tumor Markers 2131 Esophageal [books.google.com]
Treatment
Your doctor will tailor your treatment to your type of mediastinal tumor. Talk to your doctor to get more accurate information about your prognosis. [healthline.com]
For lymphomas, chemotherapy is the treatment of choice, and is possibly followed by radiation. For neurogenic tumors of the posterior mediastinum, surgery is the main treatment. The outcome depends on the type of tumor. [nlm.nih.gov]
Prognosis
Prognosis Prognosis after resection of a mediastinal tumor varies widely depending on the type of lesion resected. After resection of mediastinal cysts and benign tumors, the prognosis is generally excellent. [emedicine.medscape.com]
What is the Overall Prognosis and Survival Rate of Mediastinal Tumor? The prognosis of Mediastinal Tumors depends on the location of the tumors and whether they are benign or malignant. [epainassist.com]
Therapy in stage I tumors consists of surgical resection with good prognosis. Stage II-III requires maximal resection possible followed by radiation. [en.wikipedia.org]
Etiology
Additional diagnostic testing, usually imaging and biopsy, is indicated to determine etiology. CT with IV contrast is the most valuable imaging technique. [msdmanuals.com]
Although our team decided that it was more likely to obtain the etiology of the lung micronodules by histo-pathological analysis from nodule resection using tho-racic surgery, the patient refused the procedure. [pneumologia.eu]
Mediastinal masses in children are often symptomatic and can have a varied symptomatology and etiology. The most common symptoms at presentation are dyspnea, cough, fever, aching pain and general malaise. [learn.pediatrics.ubc.ca]
In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology [books.google.es]
Etiology Neurogenic tumors of the mediastinum arise from cells of the nerve sheath, paraganglionic tissue, and autonomic ganglia, all of which originate embryonically from the neural crest. [emedicine.medscape.com]
Epidemiology
This in turn has clarified the classification and thus the epidemiology of tumours of the mediastinum, and modern radiotherapy, chemotherapy and surgery has led to improved survival of patients at risk. [books.google.com]
[…] surgery and chemotherapy, no vascular invasion, no yolk sac or choriocarcinoma components Gross description Unencapsulated, homogenous fleshy mass with indistinct boundaries and invasion of adjacent structures, hemorrhage or necrosis Choriocarcinoma Epidemiology [pathologyoutlines.com]
The epidemiology of the thyroid carcinoma. Crit. Rev. Oncog. 1993, 4 : 25–52. PubMed Google Scholar 27. Shore R.E. Issues and epidemiological evidence regarding radiation-induced thyroid cancer. Radiat. Res. 1992, 131 : 98–111. [link.springer.com]
[…] anterosuperior mediastinal mass Pain in the chest, abdomen, or bone s (for no known reason) Skin rash or itchy skin Weight loss (for no known reason) Diagnostic Exams Flow cytometry Immunohistochemistry Immunophenotyping Progression and Transformation None Epidemiology [seer.cancer.gov]
In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology [books.google.es]
Pathophysiology
Pathophysiology Tumors and cysts of the mediastinum can produce abnormal effects at both systemic and local levels. [emedicine.medscape.com]
Staging of Alberto de Hoyos 2177 Less Common Malignant Tumors of the Diagnostic Investigation of Mediastinal 2195 The Use of Prosthetic Grafts to Replace 195 Poorly Differentiated Carcinoma of the Mediastinum 2411 2261 Benign and Malignant Neurogenic 2415 Pathophysiology [books.google.com]
Prevention
The pleomorphic aspect of the mesenchymal cell population prevented a clear classification of the tumour but revealed a high malignancy mesenchymal mediastinal neoplasia. [veterinarymedicinejournal.usamv.ro]
Reasons for Procedure Cancerous tumors must be removed to prevent local tissue damage and the spread of cancer. Without removal or treatment, the cancer could spread to other areas of the body. [winchesterhospital.org]
These type of tumors cannot be prevented. Mediastinal Tumor Menu The mediastinum is divided into three sections What are mediastinal tumors? Tumors (also called neoplasms) are masses of cells. They can be benign (not cancer) or malignant (cancer). [my.clevelandclinic.org]