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2.1
Mediastinal Neoplasm
Mediastinal Neoplasms

Images

WIKIDATA, CC BY-SA 3.0
WIKIDATA, CC BY-SA 3.0

Presentation

Major changes have recently occurred in the clinical presentation, diagnosis, and management of primary lesions of the mediastinum. [ncbi.nlm.nih.gov]

However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present. The Tabular must be reviewed for the complete diagnosis code. [icdlist.com]

On presentation, he had right sided wheezes on physical exam. [pulmonarychronicles.com]

Entire Body System

  • Pathologist

    There are two opposing schools of pathologists holding different views regarding the classification of thymic epithelial neoplasms. One school of pathologists believe that histological classification of thymomas is not possible or useful. [doi.org]

    With over 300 illustrations, mostly in full colour, and a well-referenced text, this atlas is an invaluable bench reference for the practising diagnostic pathologist and a study aid for the trainee, as well as a comprehensive source of reference for oncologists [books.google.com]

    Our multidisciplinary team of thoracic surgeons, thoracic oncologists, thoracic radiation oncologists, radiologists, pathologists, neurologists, pulmonologists and nurses provide comprehensive and state-of-the-art care for patients and families. [brighamandwomens.org]

    The collection of mediastinal tumors was left almost entirely to the pathologist as most of these entities were discovered at postmortem examination. [mdedge.com]

  • Inflammation

    We performed two biopsies, one positive for malignancy without response to medical treatment and the second reporting chronic granulomatous inflammation. [ncbi.nlm.nih.gov]

    Evaluating Mediastinal Lymph Nodes Inflammation, infection, or cancer can affect the lymph nodes in the mediastinum. [nyp.org]

    The most common complications of radiation therapy are formation of scar tissue in the lungs (pulmonary fibrosis), inflammation of the pericardium (pericarditis), and inflammation of the spinal cord (myelitis). CHEMOTHERAPY. [encyclopedia.com]

    A 20 Year-Old with a Mediastinal Mass Reviewed By Allergy, Immunology & Inflammation Assembly Submitted by Tyler B. [thoracic.org]

  • Wound Infection

    Two cases presented postoperative morbidity (one pneumonia and wound infection; and one asymptomatic right phrenic paralysis). [academic.oup.com]

    Wound infections after sternotomy or thoracotomy are rare. The chest wall has an excellent blood supply and, with few exceptions, healing occurs readily. [drminkim.com]

Respiratoric

  • Mediastinal Disease

    Mediastinal diseases are conditions that arise from tissues in this cavity. [utswmedicine.org]

    In 1888, Hare 1 collected 520 cases of mediastinal disease, over 50 per cent of which were due to tumors, mostly of the malignant type. [jamanetwork.com]

    Thyroid mass mediastinal – a benign growth such as a goiter. These masses may develop into cancer. Middle mediastinal tumors include: Bronchogenic cysts - a disease in the respiratory system. Lymphadenopathy mediastinal - disease in the lymph nodes. [cedars-sinai.edu]

    Ann Thorac Surg 57:992 CrossRef PubMed CAS Google Scholar Solaini L, Bagioni P, Campanini A et al (1998) Diagnostic role of videothoracoscopy in mediastinal disease. [link.springer.com]

  • Pneumonia

    Tumor Diameter Specific Ineligibility Criteria Any 10 cm or less Severe Interstitial pneumonia Tumor locations and histological types of past cases Region Histological Type Superior mediastinum Lymph nodes (adenocarcinoma, clear cell cancer) Anterior [hibmc.shingu.hyogo.jp]

    The most commonly-known diseases include asthma, bronchitis, pneumonia and pleurisy. Though not directly related to pulmonology, there is also thoracic surgery, which involves treating lung tumours through radiation. [nal-vonminden.com]

    The esophagus was dilated cranially due to external mass compression and aspiration pneumonia signs were found in the lung. Small nodular mases were also seen in all the lung lobes. [veterinarymedicinejournal.usamv.ro]

    In children, mediastinal masses are more likely to cause tracheobronchial compression and stridor or symptoms of recurrent bronchitis or pneumonia. Symptoms and signs also depend on location. [msdmanuals.com]

    His primary care physician prescribed a short course of antibiotics for empiric treatment of pneumonia with some initial improvement in symptoms. [thoracic.org]

  • Persistent Cough

    Other symptoms may include: Persistent cough Shortness of breath or wheezing Fever or night sweats Difficulty swallowing or hoarseness Unexplained weight loss In addition to an X-ray or CAT scan, masses are diagnosed using a scope to look inside the chest [swedish.org]

    Symptoms most often observed include persistent cough, dyspnea, and stridor. If the location and size of the mass produces partial or complete obstruction, obstructive pneumonia can also occur. [drminkim.com]

Gastrointestinal

  • Dysphagia

    Symptoms  Chest pain  Dyspnea  Cough  Fever  Weight loss  Fatigue  Dysphagia  Night sweats 16. [slideshare.net]

    Respiratory symptoms and dysphagia can occur due to bronchial and esophageal obstruction respectively. [learn.pediatrics.ubc.ca]

    Thirty to fifty percent of those with thymomas also have myasthenia gravis so symptoms of weakness, fatigue, ptosis, diplopia and dysphagia can be reported. [cancertherapyadvisor.com]

    Lesions in the posterior mediastinum may encroach on the esophagus, causing dysphagia or odynophagia. [msdmanuals.com]

Skin

  • Blister

    […] radiation can have serious side effects, such as: changes in appetite bleeding problems anemia constipation diarrhea fatigue hair loss infection nausea/vomiting pain swelling Radiation may also cause changes in the skin, like: dryness itching peeling blistering [healthline.com]

  • Erythema

    Epidermal naevi are typically asymptomatic, although large linear naevi may become spontaneously inflamed, with the development of pruritus and erythema of the lesions and surrounding skin. [intranet.tdmu.edu.ua]

Face, Head & Neck

  • Head and Neck Swelling

    If arising from the muscles of head and neck, an asymptomatic firm swelling is apparent. Orbital tumors often cause pain and swelling about the eye with proptosis and diplopia. [intranet.tdmu.edu.ua]

Neurologic

  • Irritability

    Symptoms, when present, are mainly chest pain and/or various neurological symptoms such as paralysis or medullary nervous irritation. In the majority of cases, these are detected occasionally with chest radiography. [ieo.it]

    […] of adjacent structures, hemorrhage or necrosis Choriocarcinoma Epidemiology Usually men in 20s with elevated hCG and gynecomastia, impotence Prognostic factors Poor prognosis Case reports 13 year old boy with shortness of breath, chest pain, fever, irritable [pathologyoutlines.com]

  • Seizure

    This may lead to hydrocephalus, seizures, and deterioration of central nervous system function. In these cases, cells containing melanin may be detected in the cerebrospinal fluid. [intranet.tdmu.edu.ua]

Workup

Follow-up of the patient includes clinical examination, chest radiographs, computed tomography, and metastatic workup every 6 to 12 months [10] and should be monitored closely for 10 years or less after primary diagnosis. > Conclusions This case report [cancerjournal.net]

There were 144 cases having abnormal mediastinal lesions detected on initial diagnostic workup on the chest radiology. [lungindia.com]

In many cases, no further workup is needed for diagnosis. Characterization of the mass on the CT scan is based on specific attenuation of water, air, fat, calcium, soft tissue, and vascular structures. [ncbi.nlm.nih.gov]

X-Ray

  • Mediastinal Mass

    The variation in these imaging findings played an important role in the differential diagnosis of this uncommon mediastinal mass. [ncbi.nlm.nih.gov]

    Here we describe two patients with neoplastic anterior mediastinal masses associated with GD, illustrating that this may not be safe approach to all patients with anterior mediastinal masses and GD. [thyroidresearchjournal.biomedcentral.com]

    Mediastinal Mass I. Problem/Condition. Although relatively uncommon, the precise incidence of mediastinal masses remains unclear due to lack of ubiquity in classification and definition reported in medical literature. [cancertherapyadvisor.com]

    They represent 6% of mediastinal masses, and 33% of mediastinal cysts. Neurogenic tumor: The most common cause posterior mediastinal tumors arise from nerves. They are usually benign, especially in adults. [saintjohnscancer.org]

  • Superior Mediastinal Mass

    […] abnormalities The superior mediastinal mass present above the thoracic plane (upper side): Neoplastic and non-neoplastic pathology. [cancerwall.com]

Treatment

For lymphomas, chemotherapy is the treatment of choice, and is possibly followed by radiation. For neurogenic tumors of the posterior mediastinum, surgery is the main treatment. The outcome depends on the type of tumor. [nlm.nih.gov]

For lymphomas, chemotherapy is the treatment of choice, and is possibly followed by radiation. For neurogenic tumors of the posterior mediastinum, surgery is the main treatment. Outlook (Prognosis) The outcome depends on the type of tumor. [pennmedicine.org]

Anyone looking after patients with a mediastinal mass should follow the recommendations on diagnosis, treatment, and post-treatment care. [ncbi.nlm.nih.gov]

Prognosis

Prognosis Prognosis after resection of a mediastinal tumor varies widely depending on the type of lesion resected. After resection of mediastinal cysts and benign tumors, the prognosis is generally excellent. [emedicine.medscape.com]

Therapy in stage I tumors consists of surgical resection with good prognosis. Stage II-III requires maximal resection possible followed by radiation. [en.wikipedia.org]

What is the Overall Prognosis and Survival Rate of Mediastinal Tumor? The prognosis of Mediastinal Tumors depends on the location of the tumors and whether they are benign or malignant. [epainassist.com]

Etiology

Additional diagnostic testing, usually imaging and biopsy, is indicated to determine etiology. CT with IV contrast is the most valuable imaging technique. [msdmanuals.com]

Although our team decided that it was more likely to obtain the etiology of the lung micronodules by histo-pathological analysis from nodule resection using tho-racic surgery, the patient refused the procedure. [pneumologia.eu]

In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology [books.google.es]

Mediastinal masses in children are often symptomatic and can have a varied symptomatology and etiology. The most common symptoms at presentation are dyspnea, cough, fever, aching pain and general malaise. [learn.pediatrics.ubc.ca]

Etiology Neurogenic tumors of the mediastinum arise from cells of the nerve sheath, paraganglionic tissue, and autonomic ganglia, all of which originate embryonically from the neural crest. [emedicine.medscape.com]

Epidemiology

This in turn has clarified the classification and thus the epidemiology of tumours of the mediastinum, and modern radiotherapy, chemotherapy and surgery has led to improved survival of patients at risk. [books.google.com]

[…] surgery and chemotherapy, no vascular invasion, no yolk sac or choriocarcinoma components Gross description Unencapsulated, homogenous fleshy mass with indistinct boundaries and invasion of adjacent structures, hemorrhage or necrosis Choriocarcinoma Epidemiology [pathologyoutlines.com]

The epidemiology of the thyroid carcinoma. Crit. Rev. Oncog. 1993, 4 : 25–52. PubMed Google Scholar 27. Shore R.E. Issues and epidemiological evidence regarding radiation-induced thyroid cancer. Radiat. Res. 1992, 131 : 98–111. [link.springer.com]

[…] anterosuperior mediastinal mass Pain in the chest, abdomen, or bone s (for no known reason) Skin rash or itchy skin Weight loss (for no known reason) Diagnostic Exams Flow cytometry Immunohistochemistry Immunophenotyping Progression and Transformation None Epidemiology [seer.cancer.gov]

In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology [books.google.es]

Pathophysiology

Pathophysiology Tumors and cysts of the mediastinum can produce abnormal effects at both systemic and local levels. [emedicine.medscape.com]

Staging of Alberto de Hoyos 2177 Less Common Malignant Tumors of the Diagnostic Investigation of Mediastinal 2195 The Use of Prosthetic Grafts to Replace 195 Poorly Differentiated Carcinoma of the Mediastinum 2411 2261 Benign and Malignant Neurogenic 2415 Pathophysiology [books.google.com]

Prevention

Reasons for Procedure Cancerous tumors must be removed to prevent local tissue damage and the spread of cancer. Without removal or treatment, the cancer could spread to other areas of the body. [winchesterhospital.org]

Hengityselimet Pulmonology, also known as pneumology, deals with the prevention and treatment of lung complaints. [nal-vonminden.com]

The pleomorphic aspect of the mesenchymal cell population prevented a clear classification of the tumour but revealed a high malignancy mesenchymal mediastinal neoplasia. [veterinarymedicinejournal.usamv.ro]

In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology [books.google.es]

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