CASE PRESENTATION: A 12-year-old boy presented with acute worsening and subsequent spontaneous resolution of his compensated hydrocephalus. [ncbi.nlm.nih.gov]

We report on a patient who presented a psychotic disorder (delusional type), and mega cisterna magna. [readbyqxmd.com]

An enlarged posterior fossa can sometimes be present. History and etymology The term was first coined by Gonsette et al in 1962, in patients with cerebellar atrophy. [operativeneurosurgery.com]

Case Presentation A two-year-old Caucasian male presented to our clinic following a referral for an abnormal head shape. He was developmentally normal and the mother reported no symptoms. [cureus.com]

• Inflammation

  Associations Especially if noted antenatally, a mega cisterna magna has been associated with infarction inflammation and infection (e.g. [medicalopedia.org]

  It is also associated with inflammation, infection and infarction, states Radiopaedia. The prognosis for mega cisterna magna is good when the condition occurs with normal ventricles in an isolated finding. [reference.com]

  Especially if noted antenatally, a mega cisterna magna has been associated with: Infarction Inflammation/infection: particularly cytomegalovirus Chromosomal abnormalities: especially trisomy 18 However, when a mega cisterna magna occurs as an isolated [operativeneurosurgery.com]

  Associations Especially if noted antenatally, a mega cisterna magna has been associated with: infarction inflammation/infection: particularly cytomegalovirus chromosomal abnormalities: especially trisomy 18 In children, it has also been identified in [radiopaedia.org]

• Short Stature

  In addition to these abnormalities, low birth weight and short stature are constant findings, features of a widespread skeletal disorders are more variable, and there may be associated renal abnormalities [8, 9]. [hindawi.com]

• Heart Disease

  Moss' heart disease in infants, children, and adolescents, 4th ed. Baltimore: Williams & Wilkins, 1989:530. ‏ [books.google.com]

  Moss' heart disease in infants, children, and adolescents, 4th ed. Baltimore: Williams & Wilkins, 1989:530. ‎ [books.google.ro]

  Increased frequency of an association with congenital heart disease, cleft palate, and neural tube defects appears to exist. [medicaljournal.blogspot.com]

• Fetal Disorder

  Radiology. 2000; 215: 205-210 Coakley FV Hricak H Filly RA Barkovich AJ Harrison MR Complex fetal disorders: effect of MR imaging on management—preliminary clinical experience. [ajog.org]

• Stroke

  Mega Men 50 plus: GNC Supplement Megamen 50 plus does contain ginko biloba in smaller dose.A 2008 study howed that ginko biloba could increase risk of stroke .The scintists found that those taking ginko biloba had high rate of stroke than those who were [healthtap.com]

  7th International Conference on Neurological Disorders & Stroke September 20-21, 2018 | Rome, Italy Hadi Mujlli Thamar University, Yemen Posters & Accepted Abstracts: Brain Disord Ther Abstract : Kleine-Levin syndrome (KLS) is an uncommon syndrome characterized [longdom.org]

  […] have an enhancing membrane cystic tumors: often will have a solid/enhancing component and be intra-axial pilocytic astrocytoma hemangioblastoma non-neoplastic cysts neurenteric cyst neuroglial cyst porencephalic cyst often follow a history of trauma or stroke [radiopaedia.org]

  […] without resting on the floor of the cranium, which would destroy nervous tissue.[10][11] Clinical significance[edit] The narrowness of the cerebral aqueduct and foramina means that they can become blocked, for example, by blood following a hemorrhagic stroke [en.wikipedia.org]

  She died at age 92, after suffering a number of cerebellar strokes (perhaps coincidentally, or perhaps not). Her MRI scans revealed that her cerebellum had some notable asymmetries, though not as severe as my brother’s. [medium.com]

[…] with a low‐risk serum screen for aneuploidy that the finding of an isolated mildly enlarged cisterna magna with otherwise normal intracranial anatomy, especially in the third trimester, is usually a normal variant and therefore does not require further workup [onlinelibrary.wiley.com]

• Posterior Fossa Cysts

  Dandy-Walker malformation: (A, B)The fourth ventricle opens into a large posterior fossa cyst. There is associated hydrocephalus. [medicalopedia.org]

  Abstract The mega cisterna magna is one cause of a midline, extra-axial, posterior fossa cyst. [ncbi.nlm.nih.gov]

  Dandy Walker / Dandy Walker Variant / Mega Cisterna Magna / Posterior Fossa Arachnoid Cyst DANDY WALKER MALFORMATION MoA: superior medullary velum (roof of 4th ventricle) fails to develop, foramen of Magendie and Luschka atresia posterior fossa cyst continuous [learnneurosurgery.com]

  quite enlarged posterior fossa Posterior fossa arachnoid cyst Noncommunicating posterior fossa cyst Normal but distorted vermis and cerebellum Normal but displaced fourth ventricle Usually enlarged posterior fossa Diagnosis: Dandy Walker syndrome is [medicaljournal.blogspot.com]

  Seite 175 - Revised classification of posterior fossa cysts and cyst-like malformations based on the results of multiplanar MR imaging. ‎ [books.google.de]

Treatment with amisulpride 1200 mg/day resulted in a 30% decrease in PANSS score within 2 months. Then galantamine 8 mg/day was added and PANSS score decreased further by 27% within 2 weeks. [ncbi.nlm.nih.gov]

[…] of the newborn a few hours after with cPMP through a central line with good results.8 After a daily treatment with cPMP, the patient manifested an almost normal neurodevelopment.8 Lubout et al published a case where the treatment is administered shortly [dovepress.com]

In general isolated mild cisterna magna enlargement ( between 10 to 13 mms ) is associated with good prognosis in the child after birth. [kriznanultrasoundimages.com]

We conclude that overall, the prognosis for these posterior fossa defects is grim but not uniformly fatal. The presence of other anomalies is associated with the worst prognosis. [childnervoussystem.blogspot.com]

One set of data indicates that nearly 80% of parents prefer to abort fetuses identified with PFAs in some parts of the world.1 This may be unwarranted, given that cases of isolated MCM have a favorable developmental prognosis. [consultant360.com]

The prognosis for mega cisterna magna is good when the condition occurs with normal ventricles in an isolated finding. It is usually observed on a CT/MRI or ultrasound. [reference.com]

Prognosis: Normal neurodevelopment. Recurrence: No increased risk of recurrence. [fetalmedicine.org]

It is not known whether this association is accidental or based on etiological commonality. The purpose of this case report is to review the relationship between the cerebellum and psychiatric symptoms and to contribute to the literature. [koreascience.kr]

Rarely, both of these conditions may have a common underlying etiology that may indicate a causal relationship. Further studies are required to establish a causal relationship between the mega cistern magna and the psychiatric disorders. [docksci.com]

The etiology of the disease is speculated to be the loss of Zic1/4 genes. Conclusion: This is a case of DWS managed conservatively, with surgery being the usual treatment of choice. [austinpublishinggroup.com]

Epidemiology A mega cisterna magna is thought to occur in approximately 1% of all brains imaged postnatally. Associations Especially if noted antenatally, a mega cisterna magna has been associated with infarction inflammation and infection (e.g. [medicalopedia.org]

Epidemiology A mega cisterna magna is thought to occur in ~1% of all brains imaged postnatally. [operativeneurosurgery.com]

Epidemiology. 2005;16(1):87-92. Liu Z, Han J, Fu F, et al. Outcome of isolated enlarged cisterna magna identified in utero: experience at a single medical center in mainland China. Prenat Diagn. 2017;37(6):575-582. [consultant360.com]

Epidemiology and Demographics The Dandy-Walker complex is a genetically sporadic disorder that occurs one in every 25,000 live births, mostly in females. [wikidoc.org]

Discussion Considering the pathophysiology of KLS, the hypothalamic hypo-metabolism may implicate sleep regulation, control of food intake, and sexual behavior. [scirp.org]

These studies may be particularly valuable in guiding studies on the pathophysiology and treatment of mood and psychotic disorders. Acknowledgments Fig. 1. [e-jyms.org]

[…] role in coordination and motor functions.1 Besides its involvement in motor and vestibulo-ocular regulation, it is considered to be involved in modulation of mood.2 Cerebellar structures, especially the vermis, are considered to be associated with the pathophysiology [ncbi.nlm.nih.gov]

Pathophysiology: Dandy-Walker malformations are formed during embryogenesis. Insults of varying severity to both the developing cerebellar hemispheres and fourth ventricle currently are believed to be the genesis of the anomaly. [medicaljournal.blogspot.com]

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. ‏ الصفحة 332 - Crane JP, LeFevre ML, Winborn RC, et al. [books.google.com]

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. ‎ Pagina 332 - Crane JP, LeFevre ML, Winborn RC, et al. [books.google.ro]

Recently, it has been seen that administering cPMP as substitution therapy does not improve the brain damage already produced but prevents its progressive worsening.1,2,8 In 2012, Hitzert et al published a case diagnosed prenatally, induction of labor [dovepress.com]

Consequently, it also suggested that a certain and possibly large subset of autism cases may actually be preventable with early treatment. [medium.com]

Poor perinatal outcome associated with vasa previa: is it preventable? A report of three cases and review of the literature. Ultrasound Obstet Gynecol 1998;12(6):430–3. Review. [glowm.com]