Presenting identifying characteristics ( versus group 2) are few with the exception of a lower median urine protein at presentation. [doi.org]

DISCUSSION: Simultaneous anti-GBM disease and membranous glomerulonephritis is the most common temporal presentation of this rare entity. [ncbi.nlm.nih.gov]

• Kidney Failure

  Corticosteroids: They have been tried with mixed results, with one study showing prevention of progression to kidney failure without improvement in proteinuria. [en.wikipedia.org]

  She was admitted because of acute kidney failure, bloody diarrhea, and gastrointestinal symptoms. Further evaluation confirmed the diagnosis of ulcerative colitis. [ncbi.nlm.nih.gov]

• Vaginal Bleeding

  Abstract A 26-year-old woman presented at our hospital with pretibial edema, swelling, and vaginal bleeding. [ncbi.nlm.nih.gov]

The two can be distinguished by clinical, laboratory, and histological features (see Presentation and Workup ). [1] Successful treatment of the underlying cause may be curative in secondary forms. [emedicine.medscape.com]

The diagnosis of idiopathic membranous nephropathy was established by renal biopsy as part of the routine clinical workup for the investigation of proteinuria. 8 The studies were approved by the relevant institutional review boards in the three countries [doi.org]

• Liver Function Tests Abnormal

  Other exclusion criteria were systemic diseases, pregnancy or inadequate contraception, active infection, unstable angina pectoris, diabetes mellitus, clinical evidence of renal vein thrombosis, liver function test abnormalities (>2 times the upper limit [doi.org]

Korbet SM: Treatment of primary focal segmental glomerulosclerosis. Kidney Int 2002;62:2301–2310. [doi.org]

Treatment of secondary membranous nephropathy is guided by the treatment of the original disease. For treatment of idiopathic membranous nephropathy, the treatment options include immunosuppressive drugs and non-specific anti-proteinuric measures. [en.wikipedia.org]

There is no specific treatment for membranous nephropathy. [cjasn.asnjournals.org]

Persistent proteinuria at diagnosis predicts poor prognosis. [ncbi.nlm.nih.gov]

Long-term prognosis is guarded because approximately 50% of patients may have evidence of progressive kidney disease. [biomedcentral.com]

Si-Xuan Qian, Jian-Yong Li, Ming Hong, Wei Xu and Hong-xia Qiu, Nonhematological autoimmunity (glomerulosclerosis, paraneoplastic pemphigus and paraneoplastic neurological syndrome) in a patient with chronic lymphocytic leukemia: Diagnosis, prognosis [doi.org]

Author information 1 Department of Internal Medicine, Gaziantep University, School of Medicine, Gaziantep, Turkey. [email protected] Abstract Adult onset Still's Disease (ASD) is a systemic inflammatory disorder of unknown etiology characterized by [ncbi.nlm.nih.gov]

C3 glomerulonephritis is similar in etiology to dense deposit disease, arising as a result of alternate complement activation or mutations in the complement-regulating proteins. C3NeF is commonly present. [emedicine.medscape.com]

Department of Epidemiology, Johns Hopkins University, Baltimore (A.K.); Department of Systemic Ecology, University of Bucharest, Bucharest, Romania (L.D.); Departments of Nephrology (J.M.H., J.F.M.W.), Human Genetics (M.J.H.C.), Epidemiology, Biostatistics [doi.org]

Epidemiology Frequency United States In preadolescents, minimal-change nephrotic syndrome (MCNS) makes up 85-95% of all cases of nephrotic syndrome. [emedicine.medscape.com]

Epidemiology Frequency United States Biopsy reveals an underlying glomerular lesion in 25% of adults with nephrotic syndrome. However, in patients older than 60 years, the incidence rate is 35%. [emedicine.com]

Author information 1 Pathophysiology of Renal Diseases, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan. 2 Department of Nephrology, Tokyo Medical University Kasumigaura Hospital, Ami, Ibaraki, [ncbi.nlm.nih.gov]

Corticosteroids: They have been tried with mixed results, with one study showing prevention of progression to kidney failure without improvement in proteinuria. [en.wikipedia.org]

He was started on an angiotensin-converting enzyme inhibitor to reduce proteinuria and an oral anticoagulant to prevent thromboembolic events. [ncbi.nlm.nih.gov]

The binding of NFa to C3b,Bb stabilizes the complex, preventing degradation by its normal inactivators, resulting in complement activation and chronic consumption of C3. [emedicine.medscape.com]

Penny MJ, Boyd RA, Hall BM (1998) Mycophenolate mofetil prevents the induction of active Heymann nephritis: association with Th2 cytokine inhibition. J Am Soc Nephrol 9:2272–2282 PubMed Google Scholar 27. [doi.org]