Presentation
[…] or they present with only one area of involvment. [physio-pedia.com]
Peripheral enhancement at the site of active inflammatory reaction is sometimes present whereas calcified zones remain hypointense [ 16 ], [ 17 ] (fig. 11). [em-consulte.com]
It presents in a nonspecific pattern mimicking any disease that cause pachymeningitis. [scielo.br]
Here, we report a case of NBD presenting as HP. A 25-year-old man presented with chronic headache and a 10 day history of blurred vision. [synapse.koreamed.org]
We conclude that spontaneous CSF leaks are associated with a spectrum of connective tissue abnormalities and may be the first noted clinical presentation of the genetic disorder. [spinalcsfleak.org]
Musculoskeletal
- Short Extremities
Among the features of these syndromes are high forehead, hypoplastic facies, cleft palate, short extremities (with gross distortions of the epiphyses, metaphyses, and joint surfaces), cataracts, degeneration of the vitreous, and retinal detachment. [clinicalgate.com]
Eyes
- Ectopia Lentis
Ocular problems include myopia, flat corneas, and ectopia lentis. The major life-threatening problem is aortic aneurysm or dissection; aortic and mitral valves can also be affected. [clinicalgate.com]
Neurologic
- Papilledema
Papilledema is absent, but vision may be reduced. The head becomes so enlarged that they eventually may be bedridden. [en.wikipedia.org]
An elevation and blurring of the optic disk margin (papilledema) may occur due to increased pressure in the subarachnoid space along the optic nerve. [what-when-how.com]
PSEUDOTUMOR CEREBRI Defective resorption of CSF into the superior sagittal sinus due to sinovenous thrombosis accounts for some cases of the syndrome of pseudotumor cerebri, which is characterized by headache, papilledema, increased CSF pressure and normal [neuropathology-web.org]
Same feelings in upper sections of the spine dependent on cyst locations Headaches (due to the changes in the CSF pressure) and sometimes accompanied by blurred vision, double vision, pressure behind the eyes and optic nerve pressure causing papilledema [tarlovcystfoundation.org]
Table TABLE 2 Neurologic Signs and Symptoms of Metastatic Brain Tumors Signs and symptoms Percentage of patients Hemiparesis 55 to 60 Impaired cognition 55 to 60 Headache 25 to 40 Focal weakness 20 to 30 Altered mental status 20 to 25 Sensory loss 20 Papilledema [aafp.org]
- Neck Stiffness
If you have viral meningitis, symptoms may include fever, light sensitivity, headache, and a stiff neck. [hopkinsmedicine.org]
From Wikipedia, the free encyclopedia Jump to navigation Jump to search Neck stiffness, stiff neck and nuchal rigidity are terms often used interchangeably to describe the medical condition when one experiences discomfort or pain when trying to turn, [en.wikipedia.org]
Limb pain, pale skin, and cold hands and feet often appear earlier than the rash, neck stiffness, dislike of bright lights and confusion. Septicaemia can occur with or without meningitis. [meningitis.org]
Other common symptoms include neck pain, neck stiffness, nausea, vomiting, sensitivity to light and/or sound, sense of imbalance, ringing in the ears and changes in hearing. [cedars-sinai.edu]
- Reduced Consciousness
Toxic encephalopathy, characterized by reduced consciousness, seizures, and delirium, may occur in poisoning with alcohols, sedatives, or many other chemicals or drugs—the latter usually taken in overdose or for a prolonged period. [britannica.com]
Workup
[…] headache also warrant imaging, as they may have a mass or a bleed that is gradually growing, pressing on surrounding structures and causing worsening pain.[27] People with neurological findings on exam, such as weakness, also need further workup.[27] [en.wikipedia.org]
[…] cauda equina, or subependymal areas, which extend into the sulci of the cerebrum or folia of the cerebellum MRI of the spinal cord can show nerve-root thickening, cord enlargement, intraparenchymal and subarachnoid nodules, or epidural compression See Workup [emedicine.medscape.com]
The combination of LME and pleocytosis in all cases, especially in the 2 cases with increased CSF-PMNL and fever, led to extensive virologic and bacteriologic workup, which proved negative both in blood and CSF. [nn.neurology.org]
Pediatric Sturge-Weber Syndrome: Work-up. http://emedicine.medscape.com/article/1177523-workup (accessed 12 March 2012). ↑ Akpinar, E. The Tram-Track Sign: Cortical Calcification. [physio-pedia.com]
Treatment
OBJECTIVE: To evaluate whether treatment of spinal meningeal cysts that compress sacral spinal nerve roots is associated with relief of persistent genital arousal disorder. [ncbi.nlm.nih.gov]
[…] with late effects of your treatment. [lymphomas.org.uk]
Preventive measures: avoid triggers, treatment with meds, hydration Cluster headache Less than 1/10 as common as migraine Clusters occur once to several time per day over a few weeks then vanish for months Pain is severe, described as boring sensation [brainaacn.org]
For many patients, symptoms go away without any specific treatment. Initial treatment may include bed rest, good hydration and increased caffeine intake to reduce symptoms. [cedars-sinai.edu]
This study paves the way for earlier diagnosis and earlier treatment of leptomeningeal disease. What treatments can we offer to leptomeningeal disease patients? Goals for treatment include prolonging survival and stabilizing neurological symptoms. [mdanderson.org]
Prognosis
Encephaloceles toward the front of the skull usually do not contain brain tissue and generally have a better prognosis. [rarediseases.org]
A combination of surgery, radiation, and chemotherapy treatment improves the prognosis for leptomeningeal disease. [mountsinai.org]
In this section: Definition | Symptoms | Diagnosis | Treatment | Prognosis MRI image showing a typical meningioma tumor A meningioma is a tumor that arises from a layer of tissue (the meninges) that covers the brain and spine. [neurosurgery.ucla.edu]
Prognosis of Symptomatic Tarlov Cysts Those who have progressive and prolonged symptoms run a risk of neurological damage, if the cysts continue to compress nerve structures. [tarlovcystfoundation.org]
As a result, leptomeningeal disease has a poor prognosis, with survival typically measured in months. The Neuro-Oncology department at MD Anderson is expanding its LMD program dedicated to better understanding and treating the disease. [mdanderson.org]
Etiology
The association of an infectious uveitis with an acute or chronic meningoencephalitis is unusual but occasionally the eye examination may suggest an infectious etiology or even a specific organism responsible for a meningeal syndrome. [ncbi.nlm.nih.gov]
Although a variety of etiologies have been reported, including infection, rheumatoid arthritis, sarcoidosis, Sjo¨gren syndrome, mixed connective tissue disease, ANCA-associated vasculitis and malignancy, individual etiology escapes detection in most [posterng.netkey.at]
At that time no specific etiology was found and she was released with a diagnosis of chronic rhinitis. [scielo.br]
Enzyme deficiencies are the cause of some cases of hereditary motor neuropathy, but in most cases the etiological basis of the disease is unknown. [britannica.com]
The etiology is unknown; at present we do not know what causes this disease. It is a devastating disease in some patients that can produce a multitude of symptoms. [archive.myelitis.org]
Epidemiology
Grajales-Muñize a Surgeon specialising in Epidemiology and Professor of Hospital Administration and Public Health, Epidemiological Surveillance Management, Mexican Social Security Institute, Mexico City, Mexico b Surgeon specialising in Epidemiology, [elsevier.es]
Epidemiologic data were collected and the type, number, and location of the meningeal cysts in each patient were determined on magnetic resonance imaging. [ncbi.nlm.nih.gov]
Most registries and epidemiological studies classify encephaloceles using broad categories like frontal, parietal, occipital and sphenoidal. [rarediseases.org]
"Epidemiology and etiology of meningioma". Journal of Neuro-Oncology. 99 (3): 307–14. doi : 10.1007/s11060-010-0386-3. PMC 2945461. PMID 20821343. ^ a b Starr, CJ; Cha, S (26 May 2017). [en.wikipedia.org]
Pathophysiology
This chart roughly demonstrates the relationships between the meningeal anatomy and the pathophysiology. Emerald green arrows indicate the flow chart from the skull to the pia, from outer to the parenchyma. [posterng.netkey.at]
Side of headache often corresponds to side of pathology (but not always) Vascular headache Migraine (term also used to mean cluster headache) Pathophysiology thought to involve inflammatory, autonomic, serotonergic, neuroendocrine, and other influences [brainaacn.org]
The newly discovered vessels — which were also identified in human samples — could explain a variety of pathophysiological conundrums, namely how the immune system contributes to neurological and psychiatric disease. [scientificamerican.com]
The pathophysiology of HP is not well understood, although subacute or chronic meninigeal inflammation has been considered as potential causes. In this case, during the differential diagnosis, BD was revealed. [synapse.koreamed.org]
Pathophysiology, clinical manifestations and diagnosis of migraine in adults. In: UpToDate, Post TW (Ed), UpToDate, San Francisco, CA. (Accessed on April 23, 2014.) ^ Goadsby, P.J. (January 2009). [en.wikipedia.org]
Prevention
Prevention As several types of bacteria can cause bacterial meningitis, so a range of vaccines is necessary to prevent infection. The first vaccine was created in 1981 to protect against 4 of the 13 subtypes of N. meningitides. [medicalnewstoday.com]
Can herpes meningoencephalitis be prevented? Avoiding herpes virus infections in the first place can help you prevent herpes meningoencephalitis. [hopkinsmedicine.org]
Treatable - 0% Emergent - ED Care Needed - Preventable/Avoidable - 0% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary [medicbind.com]
Prevention Common bacteria or viruses that can cause meningitis can spread through coughing, sneezing, kissing, or sharing eating utensils, a toothbrush or a cigarette. These steps can help prevent meningitis: Wash your hands. [mayoclinic.org]
Collaborative Meta-Analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients. [books.google.es]