Presentation
[…] or they present with only one area of involvment. [physio-pedia.com]
It presents in a nonspecific pattern mimicking any disease that cause pachymeningitis. [scielo.br]
Here, we report a case of NBD presenting as HP. A 25-year-old man presented with chronic headache and a 10 day history of blurred vision. [synapse.koreamed.org]
We conclude that spontaneous CSF leaks are associated with a spectrum of connective tissue abnormalities and may be the first noted clinical presentation of the genetic disorder. [spinalcsfleak.org]
Peripheral enhancement at the site of active inflammatory reaction is sometimes present whereas calcified zones remain hypointense [ 16 ], [ 17 ] (fig. 11). [em-consulte.com]
Entire Body System
- Fever
Patients with nonbacterial, or aseptic, meningitis also have fever, headache, and other meningeal signs, but they are not so obviously ill. [britannica.com]
If you have viral meningitis, symptoms may include fever, light sensitivity, headache, and a stiff neck. [hopkinsmedicine.org]
Symptoms may include: Fever and chills Fatigue (feeling tired) Vomiting Cold hands and feet Severe aches or pain in the muscles, joints, chest, or abdomen (belly) Rapid breathing Diarrhea In the later stages, a dark purple rash (see photos) [cdc.gov]
Viral meningitis usually begins with symptoms of a viral infection such as fever, a general feeling of illness, headache, and muscle aches. [msdmanuals.com]
Early signs include a fever and stiff neck, headache, nausea, vomiting, confusion, and increased sensitivity to light. Immediate medical attention is essential. Vaccination is important to prevent meningitis. [medicalnewstoday.com]
- Swelling
This disorder also causes brain swelling and a rise in intracranial pressure. Head injuries, encephalitis, abscesses, lack of oxygen, tumours, strokes, and toxic agents are the most common causes of cerebral edema. [britannica.com]
When someone has meningococcal meningitis, the bacteria infect the lining of the brain and spinal cord and cause swelling. [cdc.gov]
In 80 percent of cases, the brain MRI shows a series of findings known as SEEPS: Subdural fluid collections Enhancement of the meninges Engorgement of venous structures Pituitary swelling Sagging of the brain Spinal imaging using CT, MRI and digital subtraction [cedars-sinai.edu]
Respiratoric
- Cough
Viral meningitis can be caused by different viruses, and is spread between people by coughing or sneezing, or through poor hygiene. Other germs can be found in sewage polluted water. [columbianeurology.org]
When you need to cough or sneeze, be sure to cover your mouth and nose. If you're pregnant, take care with food. Reduce your risk of listeriosis by cooking meat, including hot dogs and deli meat, to 165 F (74 C). [mayoclinic.org]
These headaches can be treated with indomethacin. primary cough headache: starts suddenly and lasts for several minutes after coughing, sneezing or straining (anything that may increase pressure in the head). [en.wikipedia.org]
The bacteria that cause meningitis usually pass from one person to another, for example, through droplets in coughs and sneezes or through saliva or spit. Some types can spread through food. [medicalnewstoday.com]
They're commonly transmitted by coughing, sneezing, and kissing, but they can't live outside the human body for very long. [medbroadcast.com]
Gastrointestinal
- Constipation
Pelvic disorders are not typical for meningitis; only in severe cases, there incontinence of urine and feces; in children of early age at onset, there is diarrhea, and later constipation. Mental disorders in acute M. constant. [medicalency.com]
Symptoms can include loss of balance, muscle spasms, numbness, tingling, coordination problems, walking issues, tremors, weakness, constipation, urinary issues, vision issues, facial pain, decreased attention span, poor judgment, memory loss, reasoning [nrc.md]
Some individuals may have difficulty empting the bladder and constipation has also been reported. Changes in sexual function such as impotence can also occur. [rarediseases.org]
[…] paralysis, most often affecting the legs but sometimes also the arms or chest/abdomen (tummy) loss of sensation or a change in sensation, most often affecting the legs but sometimes also the arms or chest/abdomen a change in bowel function (for example, constipation [lymphomas.org.uk]
- Projectile Vomiting
[…] increases in ICP Symptoms/ signs of increased ICP Headache- worse in morning because brain edema rises overnight from lying down Altered mental status- *** most important indicator; irritability and depressed level of alertness and attention Nausea and projectile [brainaacn.org]
- Muscle Rigidity
Malignant hyperthermia is a metabolic muscle disease characterized by high fever and extreme rigidity of muscles, usually caused by certain anesthetics or muscle-relaxant medications given during surgery. [britannica.com]
Cardiovascular
- Hypertension
Meningeal syndrom (signs and symptoms) Intracranial hypertension signs headache, nausea, vomitus Radicular irritation resulting in muscle spasms (meningeal signs) stiff neck spine sign Lassegue sign + Other signs of CNS disorders focal neurologic signs [lf2.cuni.cz]
[…] engorgement and elevation of optic disc; sometimes also see retinal hemorrhage Visual loss caused by transient or permanent optic nerve damage Diplopia caused by traction on CN VI, causing unilateral or bilateral abducens nerve palsies Cushing’s triad- hypertension [brainaacn.org]
Benign intracranial hypertension is a condition in which there is increased intracranial pressure caused by various metabolic and endocrine diseases; lesions and fluid obstruction are absent. [britannica.com]
The build-up of CSF can cause intracranial hypertension – an increase in pressure around the brain. Symptoms of intracranial hypertension include: a change in consciousness (becoming drowsy and unresponsive) headaches vomiting. [lymphomas.org.uk]
Musculoskeletal
- Neck Pain
See also[edit] Neck pain Acquired torticollis References[edit] ^ "Neck pain". MedlinePlus. National Institutes of Health. 5 March 2015. Retrieved 27 October 2015. ^ "Neck pain and stiff neck". NHS Choices. National Health Service. 10 December 2014. [en.wikipedia.org]
Other common symptoms include neck pain, neck stiffness, nausea, vomiting, sensitivity to light and/or sound, sense of imbalance, ringing in the ears and changes in hearing. [cedars-sinai.edu]
Mild-to-severe body pain: This can take many forms – headaches, pressure at the base of the skull, neck pain, arm pain, torso pain, hip pain, thigh pain, leg pain, numbness, facial pain, etc. [seeingyouwell.com]
At least a quarter of patients first have symptoms following relatively minor head or neck injury. Most symptomatic patients have pressing occipital headache and neck pain. [clinicalgate.com]
[…] muscles contract involuntarily, resulting in neck pain and resistance to neck flexion) Diagnosis- symptoms may progress over hours or weeks; sample of CSF by lumbar puncture; CT before LP because removing CSF if there is a mass can cause herniation Treatment [brainaacn.org]
Eyes
- Visual Impairment
impairment; due to a lesion of the occipital lobe extending from primary visual cortex into visual association cortex aphasia syndrome of disordered expression or comprehension of spoken and/or written language caused by brain injury; see also non-fluent [strokecenter.org]
Neurologic
- Stroke
Please see the National Institute of Neurological Disorders and Stroke (NINDS) for more information on brain tumors. [hydroassoc.org]
Collaborative Meta-Analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients. [books.google.es]
Seizures and stroke may occur. In young children, the fever may cause vomiting and they may refuse to eat. Young children may become very irritable and cry. There may be seizures. [my.clevelandclinic.org]
Loss of brain cells, which happens if you suffer a stroke, can affect your ability to think clearly. Brain tumors can also press on nerves and affect brain function. Some brain diseases are genetic. [icdlist.com]
The outlook for people who develop brain damage or stroke with TB meningitis is not as good. Increased pressure in the brain strongly indicates a poor outlook for a person. [healthline.com]
- Papilledema
Papilledema is absent, but vision may be reduced. The head becomes so enlarged that they eventually may be bedridden. [en.wikipedia.org]
PSEUDOTUMOR CEREBRI Defective resorption of CSF into the superior sagittal sinus due to sinovenous thrombosis accounts for some cases of the syndrome of pseudotumor cerebri, which is characterized by headache, papilledema, increased CSF pressure and normal [neuropathology-web.org]
An elevation and blurring of the optic disk margin (papilledema) may occur due to increased pressure in the subarachnoid space along the optic nerve. [what-when-how.com]
Same feelings in upper sections of the spine dependent on cyst locations Headaches (due to the changes in the CSF pressure) and sometimes accompanied by blurred vision, double vision, pressure behind the eyes and optic nerve pressure causing papilledema [tarlovcystfoundation.org]
Table TABLE 2 Neurologic Signs and Symptoms of Metastatic Brain Tumors Signs and symptoms Percentage of patients Hemiparesis 55 to 60 Impaired cognition 55 to 60 Headache 25 to 40 Focal weakness 20 to 30 Altered mental status 20 to 25 Sensory loss 20 Papilledema [aafp.org]
- Neck Stiffness
If you have viral meningitis, symptoms may include fever, light sensitivity, headache, and a stiff neck. [hopkinsmedicine.org]
From Wikipedia, the free encyclopedia Jump to navigation Jump to search Neck stiffness, stiff neck and nuchal rigidity are terms often used interchangeably to describe the medical condition when one experiences discomfort or pain when trying to turn, [en.wikipedia.org]
Limb pain, pale skin, and cold hands and feet often appear earlier than the rash, neck stiffness, dislike of bright lights and confusion. Septicaemia can occur with or without meningitis. [meningitis.org]
Other common symptoms include neck pain, neck stiffness, nausea, vomiting, sensitivity to light and/or sound, sense of imbalance, ringing in the ears and changes in hearing. [cedars-sinai.edu]
- Aura
[…] no aura auras uncommonly, light sensitivity or noise sensitivity may be accompanied by running nose, tears, and drooping eyelid, often only on one side sensitivity to movement, light, and noise exacerbated by regular use of acetaminophen or NSAIDS may [en.wikipedia.org]
(classic migraine) migraine attack associated with reversible aura symptoms indicative of focal CNS dysfunction; the aura (scintillating scotoma, vertigo, paresthesias, paresis, etc) typically develops gradually over several minutes, lasts less than [strokecenter.org]
Pathophysiology thought to involve inflammatory, autonomic, serotonergic, neuroendocrine, and other influences on blood vessel caliber in the head 75% have + family history Sx provoked by foods, stress, eye strain, menstrual cycle, changes in sleep Aura [brainaacn.org]
There is no aura, but visual sparkles and scotomas can punctuate the peaks of headache. Neck pain without radicular features is common. Patients may have evanescent hand paresthesias and other generalized musculoskeletal complaints. [clinicalgate.com]
- Kernig's Sign
Efficacy: Meningeal signs Do not rely on these signs due to low efficacy Kernig's Sign and Brudzinski's Sign Test Sensitivity : 5% Test Specificity : 95% Nuchal Rigidity Test Sensitivity : 30% Test Specificity : 68% References Thomas (2002) Clin Infect [fpnotebook.com]
[…] of positive Kernig's sign or Brudziński sign. [en.wikipedia.org]
A case was considered to be probable if the patient had a fever and two or more of the following signs or symptoms: (a) meningeal disorders: bulging fontanelle (<1 year), stiff neck, Kernig's sign, Brudzinski's sign, lumbar pain or photophobia; (b) cephalic [elsevier.es]
[…] fiber electromyography; increased in myasthenia gravis juvenile myoclonic epilepsy (JME) primary generalized epilepsy syndrome usually beginning between ages 5 to 17 years, characterized by myoclonic (muscle-jerk), absence, and tonic-clonic seizures Kernig [strokecenter.org]
Workup
[…] headache also warrant imaging, as they may have a mass or a bleed that is gradually growing, pressing on surrounding structures and causing worsening pain.[27] People with neurological findings on exam, such as weakness, also need further workup.[27] [en.wikipedia.org]
[…] cauda equina, or subependymal areas, which extend into the sulci of the cerebrum or folia of the cerebellum MRI of the spinal cord can show nerve-root thickening, cord enlargement, intraparenchymal and subarachnoid nodules, or epidural compression See Workup [emedicine.medscape.com]
The combination of LME and pleocytosis in all cases, especially in the 2 cases with increased CSF-PMNL and fever, led to extensive virologic and bacteriologic workup, which proved negative both in blood and CSF. [nn.neurology.org]
Pediatric Sturge-Weber Syndrome: Work-up. http://emedicine.medscape.com/article/1177523-workup (accessed 12 March 2012). ↑ Akpinar, E. The Tram-Track Sign: Cortical Calcification. [physio-pedia.com]
Treatment
OBJECTIVE: To evaluate whether treatment of spinal meningeal cysts that compress sacral spinal nerve roots is associated with relief of persistent genital arousal disorder. [ncbi.nlm.nih.gov]
[…] with late effects of your treatment. [lymphomas.org.uk]
For many patients, symptoms go away without any specific treatment. Initial treatment may include bed rest, good hydration and increased caffeine intake to reduce symptoms. [cedars-sinai.edu]
Preventive measures: avoid triggers, treatment with meds, hydration Cluster headache Less than 1/10 as common as migraine Clusters occur once to several time per day over a few weeks then vanish for months Pain is severe, described as boring sensation [brainaacn.org]
This study paves the way for earlier diagnosis and earlier treatment of leptomeningeal disease. What treatments can we offer to leptomeningeal disease patients? Goals for treatment include prolonging survival and stabilizing neurological symptoms. [mdanderson.org]
Prognosis
Encephaloceles toward the front of the skull usually do not contain brain tissue and generally have a better prognosis. [rarediseases.org]
A combination of surgery, radiation, and chemotherapy treatment improves the prognosis for leptomeningeal disease. [mountsinai.org]
In this section: Definition | Symptoms | Diagnosis | Treatment | Prognosis MRI image showing a typical meningioma tumor A meningioma is a tumor that arises from a layer of tissue (the meninges) that covers the brain and spine. [neurosurgery.ucla.edu]
Prognosis of Symptomatic Tarlov Cysts Those who have progressive and prolonged symptoms run a risk of neurological damage, if the cysts continue to compress nerve structures. [tarlovcystfoundation.org]
As a result, leptomeningeal disease has a poor prognosis, with survival typically measured in months. The Neuro-Oncology department at MD Anderson is expanding its LMD program dedicated to better understanding and treating the disease. [mdanderson.org]
Etiology
The association of an infectious uveitis with an acute or chronic meningoencephalitis is unusual but occasionally the eye examination may suggest an infectious etiology or even a specific organism responsible for a meningeal syndrome. [ncbi.nlm.nih.gov]
Although a variety of etiologies have been reported, including infection, rheumatoid arthritis, sarcoidosis, Sjo¨gren syndrome, mixed connective tissue disease, ANCA-associated vasculitis and malignancy, individual etiology escapes detection in most [posterng.netkey.at]
At that time no specific etiology was found and she was released with a diagnosis of chronic rhinitis. [scielo.br]
Enzyme deficiencies are the cause of some cases of hereditary motor neuropathy, but in most cases the etiological basis of the disease is unknown. [britannica.com]
The etiology is unknown; at present we do not know what causes this disease. It is a devastating disease in some patients that can produce a multitude of symptoms. [archive.myelitis.org]
Epidemiology
Grajales-Muñize a Surgeon specialising in Epidemiology and Professor of Hospital Administration and Public Health, Epidemiological Surveillance Management, Mexican Social Security Institute, Mexico City, Mexico b Surgeon specialising in Epidemiology, [elsevier.es]
Epidemiologic data were collected and the type, number, and location of the meningeal cysts in each patient were determined on magnetic resonance imaging. [ncbi.nlm.nih.gov]
Most registries and epidemiological studies classify encephaloceles using broad categories like frontal, parietal, occipital and sphenoidal. [rarediseases.org]
"Epidemiology and etiology of meningioma". Journal of Neuro-Oncology. 99 (3): 307–14. doi : 10.1007/s11060-010-0386-3. PMC 2945461. PMID 20821343. ^ a b Starr, CJ; Cha, S (26 May 2017). [en.wikipedia.org]
Pathophysiology
This chart roughly demonstrates the relationships between the meningeal anatomy and the pathophysiology. Emerald green arrows indicate the flow chart from the skull to the pia, from outer to the parenchyma. [posterng.netkey.at]
Side of headache often corresponds to side of pathology (but not always) Vascular headache Migraine (term also used to mean cluster headache) Pathophysiology thought to involve inflammatory, autonomic, serotonergic, neuroendocrine, and other influences [brainaacn.org]
The newly discovered vessels — which were also identified in human samples — could explain a variety of pathophysiological conundrums, namely how the immune system contributes to neurological and psychiatric disease. [scientificamerican.com]
The pathophysiology of HP is not well understood, although subacute or chronic meninigeal inflammation has been considered as potential causes. In this case, during the differential diagnosis, BD was revealed. [synapse.koreamed.org]
Pathophysiology, clinical manifestations and diagnosis of migraine in adults. In: UpToDate, Post TW (Ed), UpToDate, San Francisco, CA. (Accessed on April 23, 2014.) ^ Goadsby, P.J. (January 2009). [en.wikipedia.org]
Prevention
Prevention As several types of bacteria can cause bacterial meningitis, so a range of vaccines is necessary to prevent infection. The first vaccine was created in 1981 to protect against 4 of the 13 subtypes of N. meningitides. [medicalnewstoday.com]
Can herpes meningoencephalitis be prevented? Avoiding herpes virus infections in the first place can help you prevent herpes meningoencephalitis. [hopkinsmedicine.org]
Prevention Common bacteria or viruses that can cause meningitis can spread through coughing, sneezing, kissing, or sharing eating utensils, a toothbrush or a cigarette. These steps can help prevent meningitis: Wash your hands. [mayoclinic.org]
Treatable - 0% Emergent - ED Care Needed - Preventable/Avoidable - 0% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary [medicbind.com]
Collaborative Meta-Analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients. [books.google.es]