Symptoma

Meningeal Melanocytoma

The 17th case of an intracranial meningeal melanocytoma is presented in a 67-year old man. It is the 6th melanocytoma arising from the cavum Meckeli and the first presenting with seizures. [ncbi.nlm.nih.gov]

  • Intermittent Claudication

    Our patient experienced numbness and tingling in her left leg for 8 years, and low back pains with intermittent claudication for the previous 2 months. A histologically benign 20-mm tumour was totally resected. Radiation therapy was not given. [ncbi.nlm.nih.gov]

  • Fecal Incontinence

    The patient's presenting symptoms were characteristic of a large bifrontal lesion and included headaches, personality change, lethargy, and urinary and fecal incontinence. [ncbi.nlm.nih.gov]

  • Malocclusion

    Here, we report a case of a 39-year-old Japanese man who had a history of pain and numbness on the left side of his face and malocclusion for 3 months before the initial visit. [ncbi.nlm.nih.gov]

  • Retinal Pigmentation

    Bilateral naevus of Ota with choroidal melanoma and diffuse retinal pigmentation in a dark skinned person. Br J Ophthalmol. 2005;89:1529–45S. 46. Singh M, Kaur B, Annuar NM. Malignant melanoma of the choroid in a naevus of Ota. [docksci.com]

  • Macula

    Jurgens I, Roca G, Sedo S, Pujol O, Berniell JA, Quinatana M (1994) Presumed melanocytoma of the macula. Arch Ophthalmol 112: 305–306 23. [slideheaven.com]

  • Subcutaneous Nodule

    Radhadevi et al reported a 45-year-old male with malignant melanoma of the left orbit in association with nevus of Ota and MartínezPe nuela et al reported a 24-year-old man who presented with a subcutaneous nodule that had developed in the anterolateral [docksci.com]

  • Progressive Hearing Loss

    Two women, aged 21 and 30 years, were admitted to the hospital 60 years apart: the first because of progressive paraplegia and the second because of slowly progressive hearing loss. [ncbi.nlm.nih.gov]

  • Irregular Menstruation

    The patient presented with visual impairment and irregular menstruation with no other symptoms. Her general examination was otherwise unremarkable. Endocrine tests disclosed normal endocrine function except for slight hyperprolactinemia. [ncbi.nlm.nih.gov]

  • Amenorrhea

    In this paper, we report an instructive new case of a 31-year-old woman presenting with a 2-year history of amenorrhea and an intrasellar mass with suprasellar extension, suggestive of hemorrhagic pituitary adenoma. [ncbi.nlm.nih.gov]

  • Cesarean Section

    Premature rupture of the membrane occurred at 28 weeks of gestation, so this baby boy was delivered by emergency cesarean section. [ncbi.nlm.nih.gov]

  • Urinary Retention

    A 68-year-old female presented symptoms of urinary retention, loss of strength and lower limb dysesthesias of about 20 days’ evolution. [elsevier.es]

  • Meningism

    Meningeal melanocytoma is an essentially benign melanotic tumor, derived from the melanocytes of the leptomeninges, and may occur anywhere in the cranial and spinal meninges. [ncbi.nlm.nih.gov]

  • Tingling

    Our patient experienced numbness and tingling in her left leg for 8 years, and low back pains with intermittent claudication for the previous 2 months. A histologically benign 20-mm tumour was totally resected. Radiation therapy was not given. [ncbi.nlm.nih.gov]

  • Hyperreflexia

    The neurologic examination revealed that the patient had left-sided lower extremity weakness of 4 , decreased sensation on the right side, and hyperreflexia in both legs. Department of Neuroradiology interpreted CT and MR imaging as meningiom. [ncbi.nlm.nih.gov]

  • Motor Symptoms

    In the present study, a 58 year old lady presented with bilateral sensory and motor symptoms in the lower limbs. [ncbi.nlm.nih.gov]

  • Foster-Kennedy Syndrome

    Fundoscopy showed left optic nerve atrophy and right papilledema consistent with Foster-Kennedy syndrome. Neurological exams were otherwise normal. [ncbi.nlm.nih.gov]

The histological workup following subtotal tumor resection of the initial tumor had revealed the typical features of a fibrous melanocytic meningioma without increased proliferation. [thejns.org]

It is important to differentiate primary melanin-containing lesions of the CNS from metastatic melanoma, because these lesions require a different patient workup and alternate therapeutic options. [pubs.rsna.org]

  • Hyperprolactinemia

    Endocrine tests disclosed normal endocrine function except for slight hyperprolactinemia. Magnetic resonance imaging revealed a sellar lesion. The patient underwent a successful total transsphenoidal removal of the tumor without neurologic sequelae. [ncbi.nlm.nih.gov]

The treatment of choice for SPMM is complete surgical resection via a transsphenoidal approach. For patients with a partially resected tumor, radiotherapy is an effective complementary treatment modality. [ncbi.nlm.nih.gov]

Meningeal melanocytoma is a rare benign tumor with relatively good prognosis. However, local aggressive behavior of meningeal melanocytoma has been reported, especially in cases of incomplete surgical resection. [ncbi.nlm.nih.gov]

Etiology of Increased ICP Intracranial hypertension is defined as a sustained ( 5 min) elevation of ICP of 20 mmHg. Image : “MRI showing injury due to brain herniation in a patient with choriocarcinoma.” By Rocque BG, Başkaya MK (2008). [lecturio.com]

When no inflammatory, infectious or tumoral etiology or evidence of intracranial hypotension is present, a diagnosis of idiopathic pachymeningitis is considered, with possible dural calcifications. [em-consulte.com]

The -nal diagnosis was chronic intracerebral hemorrhage of unknown etiology with reactive changes of the surrounding brain tissue and perifocal extramedullary erythropoiesis. [docslide.com.br]

The lesion was excised and diagnosed as a malignant melanoma EP Conclusion TE D M AN U SC The etiology and pathogenesis of nevi of Ota and Ito are not known. [docksci.com]

Several theories for the etiology of melanotic schwannomas have been proposed, including the melanomatous transformation of neoplastic Schwann cells, phagocytosis of melanin by Schwann cells, and the simultaneous presence of two distinct neoplastic populations [pubs.rsna.org]

Their epidemiological features, natural history and response to treatment remain poorly understood, even if, in the last 2 years, some reviews have been published about it. [ncbi.nlm.nih.gov]

Changes in glycosaminoglycans, which fill the cell free space in early embryologic development, may play an important role in the neural crest migration, leading to dermal melanosis.[17] Exact pathophysiology is not yet known. [docksci.com]

Radiation therapy is important to prevent relapse of the tumor, especially in cases of incomplete surgical resection. [ncbi.nlm.nih.gov]

Radiation therapy is important to prevent relapse of the tumor when complete surgical resection is not possible. However the management of melanocytoma has no definite guidelines. [omicsonline.org]

This is helpful for the prevention of the impending complications. [lecturio.com]

Hydrocephalus is usually treated with placement of a ventriculoperitoneal shunt, but a filter must be added to the apparatus to prevent spread in the rare event of malignant transformation (10). [ajnr.org]

Rades and Schild 13 have proposed high-dose local radiation, even in cases of complete tumor resection, to prevent local recurrence. [pagepress.org]