Presentation
If an individual has both meningococcal meningitis and meningococcemia, they may present with a mixture of symptoms and signs characteristic to each of the diseases. [dermnetnz.org]
The most common clinical presentations of invasive meningococcal disease are meningitis and/or septicaemia. Meningococcal meningitis usually presents with sudden onset of fever, intense headache, neck stiffness, nausea and vomiting. [travelhealthpro.org.uk]
[…] display the following symptoms; High fever Feeling lethargic, drowsy, irritable or confused Vomiting and diarrhoea Hands and feet feeling cold Pain and soreness in the joints and muscles Patients who have meningococcal meningitis are also likely to present [doctordoctor.com.au]
Petechiae are often also present, but do not always occur, so their absence should not be used against the diagnosis of meningococcal disease. [en.wikipedia.org]
Conclusion Our results demonstrate a further means by which passive smoking presents a significant risk to the health and wellbeing of young children. [bmcpublichealth.biomedcentral.com]
Entire Body System
- Asymptomatic
There is no reservoir other than man, the vast majority of which comprises of asymptomatic carriers. [lap-publishing.com]
The impact of this intervention on asymptomatic carriage of meningococci was investigated to establish whether serogroup replacement or protection by herd immunity occurred. [emgm.eu]
Since N. meningitidis is a strict human pathogen and most patients have not been in contact with other cases, asymptomatic carriers are presumably the major source of the pathogenic strains. [ncbi.nlm.nih.gov]
Person-to-person transmission can be interrupted by chemoprophylaxis, which eradicates the asymptomatic nasopharyngeal carrier state. [emedicine.medscape.com]
- Inflammation
Viral meningitis A variety of germs (viruses) can travel to the lining that covers the brain and spinal cord (the meninges) and cause inflammation. [patient.info]
Neisseria meningitidis (the meningococcus) is an opportunistic bacterium that usually lives harmlessly in our throats but, from time to time (rarely), causes serious disease such as meningitis (inflammation of the linings of the brain) and septicaemia [nottingham.ac.uk]
Meningitis is a disease caused by the inflammation of the protective membranes covering the brain and spinal cord known as the meninges. The inflammation is usually caused by an infection of the fluid surrounding the brain and spinal cord. [community.parkview.com]
Meningitis is an infection and inflammation of your meninges. Your meninges are the thin tissues that cover your spinal cord and your brain. Meningitis can be caused by many different organisms, including bacteria, fungi, and viruses. [healthline.com]
Meningitis is an inflammation of the meninges, the membranes surrounding the brain and spinal cord. It can be caused by either bacterial or viral infection. [health24.com]
Respiratoric
- Pertussis
/ Bordetella parapertussis Pertussis γ Enterobacteriales ( OX− ) Lac+ Klebsiella pneumoniae Rhinoscleroma, Klebsiella pneumonia Klebsiella granulomatis Granuloma inguinale Klebsiella oxytoca Escherichia coli : Enterotoxigenic Enteroinvasive Enterohemorrhagic [en.wikipedia.org]
Eyes
- Photophobia
Symptoms, usually severe, include headache, nausea, vomiting, photophobia, lethargy, rash, multiple organ failure, shock, and disseminated intravascular coagulation. Diagnosis is clinical, confirmed by culture. [merckmanuals.com]
[…] following symptoms; High fever Feeling lethargic, drowsy, irritable or confused Vomiting and diarrhoea Hands and feet feeling cold Pain and soreness in the joints and muscles Patients who have meningococcal meningitis are also likely to present with photophobia [doctordoctor.com.au]
Symptoms in older children and adults Symptoms of meningococcal disease in older children and adults can include: fever headache loss of appetite neck stiffness discomfort when looking at bright lights (photophobia) nausea and/or vomiting diarrhoea aching [betterhealth.vic.gov.au]
They include: confusion a headache a high fever severe sensitivity to light, or photophobia a stiff neck vomiting Other possible, but less common, symptoms include: irritability a rash sleepiness lethargy As the disease progresses, you may experience [healthline.com]
These symptoms progress quickly to a severe muscle pains, severe headache, stiff neck, photophobia, confusion, seizures and a bruise-like rash. [meningitisbc.org]
Skin
- Skin Rash
For photographs of the characteristic skin rash, click here. Who is at risk and what are the risk factors? The age group at highest risk are children under the age of five. The peak of disease is in the first two years of life. [nottingham.ac.uk]
Neurologic
- Confusion
Its symptoms also include confusion, or irritability in infants, and a stiff neck. You should see your doctor right away if you suspect that you or a loved one might have meningococcal meningitis. [healthline.com]
Symptoms Symptoms of the disease may include: fever headache confusion or drowsiness neck stiffness joint pains rash dislike of bright lights vomiting. When diagnosed and treated with antibiotics quickly, most people will make a full recovery. [nt.gov.au]
Signs and symptoms of meningococcal disease Meningococcal meningitis Meningococcemia Children >1 year and adults Neck stiffness Headache Nausea and vomiting Neck and/or back pain Fever and chills Increased sensitivity to light Irritability, confusion [dermnetnz.org]
Symptoms Of Meningococcal Disease In Adults Patients with meningococcal diseases can become very unwell and display the following symptoms; High fever Feeling lethargic, drowsy, irritable or confused Vomiting and diarrhoea Hands and feet feeling cold [doctordoctor.com.au]
- Neck Stiffness
Symptoms Symptoms of the disease may include: fever headache confusion or drowsiness neck stiffness joint pains rash dislike of bright lights vomiting. When diagnosed and treated with antibiotics quickly, most people will make a full recovery. [nt.gov.au]
Signs and symptoms of meningococcal disease Meningococcal meningitis Meningococcemia Children >1 year and adults Neck stiffness Headache Nausea and vomiting Neck and/or back pain Fever and chills Increased sensitivity to light Irritability, confusion [dermnetnz.org]
The classic symptoms of meningitis are fever, headache and neck stiffness. Prompt diagnosis and treatment of bacterial meningitis and the associated condition of meningococcal septicaemia are vital for a good outcome and recovery. [health24.com]
In older children and adults: headache photophobia (dislike of bright lights) fever leg pain, cold extremities unusual skin colour vomiting and / or diarrhoea neck stiffness or aching backache joint pains, sore muscles, cold hands and leg pain general [health.gov.au]
Stiff neck - cannot bend the neck forward. Headache - which can become severe. Fast breathing. Aches and pains in muscles or joints - the pains can become quite severe. The skin may look pale or blotchy, or turn blue. [patient.info]
- Stroke
According to the National Institute of Neurological Disorders and Stroke (NINDS), the infection is fatal in 10 to 15 percent of cases, even with treatment. [healthline.com]
Even if the disease is quickly diagnosed and treated, 11-19 percent of survivors will experience life-changing consequences, such as loss of hearing or limbs, strokes, or seizures. [blog.pkids.org]
Treatment
Urgent treatment is essential for bacterial meningitis and septicaemia. If your doctor suspects you have bacterial meningitis, he or she will hospitalise you for treatment with antibiotics, and other supportive care. [health24.com]
For more information about preventive treatment of close contacts, click here. [meningitis.ca]
The sooner people receive treatment, the less damage the disease may cause. It is important to remember that this is an unpredictable infection that can progress very rapidly, despite the best treatment. [betterhealth.vic.gov.au]
Maintenance treatment, where the member's symptoms are neither regressing or improving, is considered not medically necessary. [tarsashazi-halozat.hu]
Prognosis
With prompt treatment, the prognosis is excellent. [en.wikipedia.org]
Bacterial causes The outlook (prognosis) often depends on how soon antibiotics are given after the illness starts. Most people make a good recovery if treated early enough. Without treatment, most people will die. [patient.info]
View Article PubMed Google Scholar Burman LA, Norrby R, Trollfors B: Invasive pneumococcal infections: incidence, predisposing factors, and prognosis. Rev Infect Dis. 1985, 7 (2): 133-142. 10.1093/clinids/7.2.133. [bmcpublichealth.biomedcentral.com]
Epidemiology
Descriptive Epidemiology 587 Mechanisms and Routes of Transmission 7 Pathogenesis and Immunity 590 Patterns of Host Response 591 Control and Prevention 592 References 593 Suggested Reading 595 Rocky Mountain Spotted Fever Theodore E Woodward and J Stephen [books.google.de]
Abstract An epidemiological study was carried out to determine meningococcal carrier state amongst recruits of a military training centre. 360 recruits with divergent socioeconomic, ethnic backgrounds were studied. [ncbi.nlm.nih.gov]
Bookcover of Epidemiology of meningococcal carrier state amongst recruits Booktitle: LAP LAMBERT Academic Publishing (2017-04-06 ) eligible for voucher ISBN-13: 978-3-330-06713-4 ISBN-10: 3330067136 EAN: 9783330067134 Book language: English Blurb/Shorttext [morebooks.de]
Invasive Meningococcal Disease Resources Epidemiological Reports Enhanced Surveillance of Invasive Meningococcal Disease in Canada, 2006-2011. [canada.ca]
Pathophysiology
Pathophysiology, treatment and outcome of meningococcemia: a review and recent experience. Pediatr Infect Dis J 1996;15(11):967-978. 15. Pollard AJ, Levin M. Vaccines for prevention of meningococcal disease. [scielosp.org]
"Pathophysiology, treatment and outcome of meningococcemia: a review and recent experience". Pediatr. Infect. Dis. J. 15 (11): 967–78, quiz 979. doi : 10.1097/00006454-199611000-00009. PMID 8933544. ^ a b Ross SC, Densen P; Densen (September 1984). [en.wikipedia.org]
Pathogenesis and pathophysiology of bacterial meningitis. Clin Microbiol Rev 6, 118 –136. [Google Scholar] 120. Tyski, S., Grzybowska, W., Dulny, G., Berthelsen, L. & Lind, I. ( 2001 ;). [jmm.microbiologyresearch.org]
Prevention
Descriptive Epidemiology 587 Mechanisms and Routes of Transmission 7 Pathogenesis and Immunity 590 Patterns of Host Response 591 Control and Prevention 592 References 593 Suggested Reading 595 Rocky Mountain Spotted Fever Theodore E Woodward and J Stephen [books.google.de]
Center. ‡ Professor of preventive medicine and chairman, Department of Preventive Medicine, State University of New York Upstate Medical Center. [nejm.org]
Immunoprophylaxis Vaccination is used for close contacts of patients with meningococcal disease due to A, C, Y, or W135 serogroups, to prevent secondary cases. [17] Current meningococcal vaccines are indicated for active immunization to prevent invasive [emedicine.medscape.com]
With no parents to keep an eye on them, meningitis can be missed Preventing meningitis Vaccines are the only way to prevent serious diseases like meningitis. [meningitisnow.org]
Conjugate vaccines are used in prevention (into routine immunization schedules and preventive campaigns) and outbreak response: They confer longer-lasting immunity (5 years and more), prevent carriage and induce herd immunity. [who.int]