Similarly, 65% of the patients who presented in coma died, compared with 12.5% who did not present in coma (p < 0.000001). [ncbi.nlm.nih.gov]

• Pharyngitis

  Abstract We are presenting a case of a 19-year-old college student with sudden-onset, asymmetric polyarticular arthritis with Neisseria meningitidis 10 days after an acute upper respiratory infection consisting of fevers, chills, pharyngitis, and productive [ncbi.nlm.nih.gov]

• Nausea

  It can also cause nausea, vomiting, and sensitivity to light. Infants may have feeding problems and a weak cry, and they may be irritable and sluggish. Bloodstream infections may cause a rash of red or purple spots. [merckmanuals.com]

• Arthritis

  Primary meningococcal septic arthritis is a rare entity. A majority of these cases present in a monoarticular fashion. The synovial fluid findings, although compatible with inflammatory arthritis, are not typical of septic arthritis. [ncbi.nlm.nih.gov]

• Purpura

  Fever was the most common manifestation (100 %) followed by meningeal signs (78.2 %), headache (56.4 %), vomiting (53.6 %), shock (38.2 %), low Glasgow coma scale (GCS) (25.5 %), purpura and rashes (23.6 %), seizures (9.1 %), abdominal symptoms (4.5 % [ncbi.nlm.nih.gov]

  Fulminant meningococcemia syndromes include Waterhouse-Friderichsen syndrome (septicemia, profound shock, cutaneous purpura, adrenal hemorrhage), sepsis with multiple organ failure, shock, and disseminated intravascular coagulation. [merckmanuals.com]

• Petechiae

  Gram-negative diplococci were found in specimens from skin films in 80% (24/30) patients with petechiae. This is significantly better than results reported for Gram-staining of needle aspirates from petechiae (46%; 12/26). [ncbi.nlm.nih.gov]

• Hearing Impairment

  impairment in 0.9 % each. [ncbi.nlm.nih.gov]

• Headache

  Fever was the most common manifestation (100 %) followed by meningeal signs (78.2 %), headache (56.4 %), vomiting (53.6 %), shock (38.2 %), low Glasgow coma scale (GCS) (25.5 %), purpura and rashes (23.6 %), seizures (9.1 %), abdominal symptoms (4.5 % [ncbi.nlm.nih.gov]

  Meningitis often causes fever, headache, red rash, and a stiff neck. It can also cause nausea, vomiting, and sensitivity to light. Infants may have feeding problems and a weak cry, and they may be irritable and sluggish. [merckmanuals.com]

• Confusion

  Our review of the literature disclosed that current classifications are confusing since they fail to differentiate between two distinct criteria: time and causality. [ncbi.nlm.nih.gov]

Abstract Aggressive early treatment of meningococcal disease can reduce mortality. [ncbi.nlm.nih.gov]

It is essential that clinicians recognize the various states of the disease, since they differ in natural history, treatment and prognosis. [ncbi.nlm.nih.gov]

The potential etiologies of sudden acquired deafness are diverse, but a thorough evaluation is warranted and may be rewarding, even if it is initiated weeks after onset of deafness. [ncbi.nlm.nih.gov]

A conventional epidemiological approach was taken, supported by routine and novel diagnostic techniques. [ncbi.nlm.nih.gov]

Determining cytokine concentrations could prove to be a valuable tool in evaluating the pathophysiology of myocardial infarction during infectious processes. [ncbi.nlm.nih.gov]

The unpredictability of infection coupled with the poor prognosis for some patients suggests immunization as an effective preventive strategy. [ncbi.nlm.nih.gov]