And if your blood sugar is high, you might notice the signs and symptoms of diabetes — such as increased thirst and urination, fatigue, and blurred vision. [mayoclinic.org]

The patient is readily fatigued and daily routines will take longer. Memory is often affected from an early stage and the patient becomes apathetic and sluggish. Some patients may also show low mood and irritability. [alzheimer-europe.org]

Hypothyroidism slows body processes and causes fatigue (tiredness), slow heart rate, excessive weight gain, and constipation. Kids and teens with this condition can be treated with oral thyroid hormone. [kidshealth.org]

Characterized by hyperglycemia, symptoms of diabetes include frequent urination, increased thirst, dehydration, weight loss, blurred vision, fatigue, and, occasionally, coma. [encyclopedia.com]

Symptoms of Inherited Metabolic Diseases can include a failure to thrive, seizures and other neurologic disorders, developmental delays, abnormal blood tests and hypotonia (abnormal loss of muscle tone). [mountsinaifpa.org]

Undernutrition is a condition in which there is insufficient food to meet energy needs; its main characteristics include weight loss, failure to thrive, and wasting of body fat and muscle. [britannica.com]

In addition, children with unexplained developmental delay, deafness, dysmorphism, congenital malformations, acidosis, failure to thrive, feeding problems, short stature, birth defects, and other syndromes of unknown cause may qualify. [clinicaltrials.gov]

Most clinical manifestations of lysinuric protein intolerance ( i.e. failure to thrive, gastrointestinal disease, bone-marrow abnormalities, osteoporosis and renal disease) have been well characterised and are related to the metabolic derangement [ 69 [err.ersjournals.com]

The more severe IEMs may cause failure to thrive or develop properly, abnormally small or large body parts, bone deformities, or general lethargy. [encyclopedia.com]

Gastrointestinal symptoms (transient abdominal pain, diarrhea or nausea) are the most common side effects reported for metformin use (81). [frontiersin.org]

Tangier, sialidosis Corneal opacity Oligosaccharidoses, Fabry disease, steroid sulfatase deficiency (X-linked ichthyosis), Tangier, molybdenum cofactor deficiency, sulfite oxidase deficiency Dislocated lens Homocystinuria, sulfite oxidase deficiency Kayser-Fleischer [content.iospress.com]

Diabetes, Metabolism, Nutrition, College of Medicine, Mayo Clinic 5 Sansum Diabetes Research Institute 6 Division of Endocrinology, Diabetes, and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, New York 7 Bone Densitometry Unit and Osteoporosis [doi.org]

Symptoms include a pronounced flush of the cheeks, a tall, thin frame, lens dislocation, vascular disease, and thinning of the bones (osteoporosis). Intellectual disability and psychiatric disorders also may be present. [britannica.com]

Metabolic disorders often lead to secondary diseases such as osteopenia, which is a pre-stage of osteoporosis, generating loss of bone. Dr. J. Barranger and Dr. L.W. [gesundheitsindustrie-bw.de]

A 24-hour urine calcium collection should be measured in patients with osteoporosis or patients at risk for bone loss in order to check calcium adequacy and test for hypercalciuria or malabsorption ( Grade B, BEL 2 ). Q7.2. [web.archive.org]

Syndrome Diet Journal of Nutritional Disorders & Therapy,Journal of Nutrition & Food Sciences, Journal of Food and Nutritional Disorders, Journal of Diabetes Medication & Care, Nutrition, American Journal of Physiology - Endocrinology and Metabolism, Osteoporosis [omicsgroup.org]

We present a previously healthy adolescent who was admitted to our emergency department with a four-day history of myalgia, muscle weakness and dark urine. At presentation, she was dehydrated. [ncbi.nlm.nih.gov]

When energy levels become too low, muscle weakness and exercise intolerance with muscle pain or cramps may occur. [mda.org]

Neurological disturbances are often reported with deafness, slurred speech, a gruff husky voice, muscle cramps and muscle weaknesses and carpal tunnel syndrome at the wrists. [alzheimer-europe.org]

[…] function should be monitored independently from the degree of peripheral muscle weakness. [err.ersjournals.com]

Other adverse effects of metabolic diseases include seizures, movement disorders, poor growth, muscle weakness, fasting intolerance and disproportionate illness with simple childhood infections or immunizations. [kennedykrieger.org]

A 4-month-old female baby visited an outpatient clinic due to poor weight gain, repeated seizure-like episodes, developmental delay, and unexplained hepatomegaly with abnormal liver function test results. [ncbi.nlm.nih.gov]

Life-threatening symptoms, such as breathing problems, seizure and organ failure can occur with acute metabolic disturbance, such as too much alcohol. [houstonmethodist.org]

Typical of: pyridoxine dependent seizures pyridoxal phosphate responsive seizures glucose transporter (GLUT-1) defect non-ketotic hyperglycinaemia molybdenum cofactor or sulphite oxidase deficiency. [bettersafercare.vic.gov.au]

Symptoms of Inherited Metabolic Diseases can include a failure to thrive, seizures and other neurologic disorders, developmental delays, abnormal blood tests and hypotonia (abnormal loss of muscle tone). [mountsinaifpa.org]

Non-ketotic hyperglycinemia is characterized by seizures, low muscle tone, hiccups, breath holding, and severe developmental impairment. [britannica.com]

Examples of conditions that come in genetically determined and nongenetic types include dementias of the subtypes Alzheimer, Pick, frontotemporal, Parkinson disease, amyotrophic lateral sclerosis, and peripheral neuropathies. [emedicine.medscape.com]

Most commonly, it affects the nerves in the feet, legs, hands, and arms; this condition is called peripheral neuropathy. Peripheral neuropathy can cause tingling, burning, pain, or numbness in the affected areas. [everydayhealth.com]

neuropathy Congenital disorders of protein glycosylation, leukodystrophies, peroxisomal disorders, Tangier disease Psychoses Adult MLD Tay-Sachs, homocystinuria, porphyrias, purine metabolism disorders Skin Hypopigmentation or absent pigment Cystinosis [content.iospress.com]

The reduced blood flow leads to reduced oxygen delivery to needy tissues, resulting in increased peripheral neuropathy commonly seen in diabetes. [drlam.com]

Other symptoms of kwashiorkor include apathy, hair discoloration, and dry, peeling skin with sores that fail to heal. [britannica.com]

These lipids accumulate in the brain and cause severe problems including blindness, deafness, apathy, and death usually before age of five years. [encyclopedia.com]

Some metabolic disorders cause liver cirrhosis in infants and children and some liver disorders progress to stupor and coma. Liver function tests commonly indicate primary liver diseases. [content.iospress.com]

Criteria include: Abdominal obesity BMI above 25 High triglycerides Low HDL cholesterol High blood pressure or using medicine to lower blood pressure High fasting blood glucose Increased blood clotting. [cedars-sinai.org]

Amino acids increase insulin secretion. It is unclear, however, whether proteins are as potent as carbohydrates in stimulating insulin secretion. [drlam.com]