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Metaproterenol
Metaproterenol (product)

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WIKIDATA, Public Domain

Presentation

Beta-agonists can sometimes increase heart rate or have other cardiovascular effects, particularly when used in high doses or if hypokalemia is present. [pdr.net]

Abstract The bronchodilator response to metaproterenol delivered by metered-dose inhaler (MDI) with a spacer device (Aerochamber [A]) and by jet nebulizer was studied in 44 asthmatic patients who presented to the emergency department with acute severe [ncbi.nlm.nih.gov]

Entire Body System

  • Fever

    More common Fast, pounding, or irregular heartbeat or pulse Less common Shakiness in the legs, arms, hands, or feet trembling or shaking of the hands or feet worsening of asthma Rare Blurred vision chest pain chills cough diarrhea dizziness fainting fever [mayoclinic.org]

    Rare: Blurred vision, dizziness, fainting, headache, fever, chills, cough, joint pains, increased sweating, diarrhoea, loss of appetite, nausea, heartburn, pharyngitis, insomnia, chest pain. Interaction : Acebutolol: Antagonism. [pediatriconcall.com]

    Side effects that you should report to your doctor or health care professional as soon as possible: blurred vision breathing problems dizziness, drowsiness fast, irregular heart rate, chest pain fever, chills high blood pressure skin rash, hives unusual [nationwidechildrens.org]

  • Intravenous Drugs

    Comprehensive foldout IV compatibility chart includes essential compatibility information for 65 intravenous drugs. Highlighted monographs for the top 204 prescribed drugs help you identify the most frequently administered drugs. [books.google.ro]

  • Anemia

    Neutropenia has numerous causes, for example, infections (HIV, TB, mono); medications (chemotherapy); vitamin deficiencies (anemia); bone marrow diseases (leukemias), radiation therapy, autoimmune destruction of neutrophils, and hypersplenism. [medicinenet.com]

Respiratoric

  • Dyspnea

    Therapy regimens that contained aminophylline were associated with less dyspnea but produced more adverse side effects and were more costly. [ncbi.nlm.nih.gov]

    […] use Adverse Reactions (Side Effects): CNS: anxiety, dizziness, headache, insomnia, nervousness, stimulation, tremors CV: cardiac arrest, dysrhythmias, hypertension, palpitations, tachycardia GI: bad taste, GI distress, nausea, vomiting RESP: cough, dyspnea [medicalcorps.org]

    PHYSICAL THERAPY IMPLICATIONS Examination and Evaluation Watch for signs of paradoxical bronchospasm, including wheezing, cough, dyspnea, shortness of breath, and tightness in chest and throat. [fadavispt.mhmedical.com]

  • Respiratory Disorders

    Chapter 41 Drugs for Lower Respiratory Disorders. Dextroamphetamine saccharate. A randomized comparison of atropine and metaproterenol inhalational therapies for refractory. Side effects include. Outline Chronic Obstructive Pulmonary. [shipsbenefits.tk]

Gastrointestinal

  • Nausea

    In addition, warned of possible S/E such as vertigo, headache, nervousness, dry and irritated throat, vomiting, nausea, dry mouth, etc. [nurseteachings.com]

    No increase in undesirable side effects (eg, nausea, tremor, palpitations) was seen in the metaproterenol-treated group. [ncbi.nlm.nih.gov]

    Side effects could include: Nervousness Headache Dizziness Drowsiness Nausea Diarrhoea Upset stomach Dry mouth Tired feeling Insomnia This is not a complete list of side effects. [clicks.co.za]

    Common side effects of metaproterenol include: nausea tremor nervousness increased heart rate headache This is not a complete list of metaproterenol side effects. Ask your doctor or pharmacist for more information. [rxwiki.com]

  • Vomiting

    In addition, warned of possible S/E such as vertigo, headache, nervousness, dry and irritated throat, vomiting, nausea, dry mouth, etc. [nurseteachings.com]

    No significant differences were observed in the frequency of nausea, vomiting, headache, or insomnia (P greater than 0.05). [ncbi.nlm.nih.gov]

    GI: vomiting, nausea, heartburn, dry mouth. Respiratory: paradoxical bronchiolar constriction with excessive use, cough, dry and irritated throat. Skin: rash, hypersensitivity reactions. Effects on lab test results None reported. [glowm.com]

    Less frequent adverse reactions are hypertension, palpitations, vomiting and bad taste. Adverse reactions would be present with an overdose. [mstcparamedic.pbworks.com]

    […] diabetes mellitus, excessive use Adverse Reactions (Side Effects): CNS: anxiety, dizziness, headache, insomnia, nervousness, stimulation, tremors CV: cardiac arrest, dysrhythmias, hypertension, palpitations, tachycardia GI: bad taste, GI distress, nausea, vomiting [medicalcorps.org]

  • Diarrhea

    Side Effects Shaking, headache, nervousness, tiredness, dizziness, upset stomach, nausea, trouble sleeping or diarrhea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. [webmd.com]

    […] following side effects occur: More common Fast, pounding, or irregular heartbeat or pulse Less common Shakiness in the legs, arms, hands, or feet trembling or shaking of the hands or feet worsening of asthma Rare Blurred vision chest pain chills cough diarrhea [mayoclinic.org]

    […] fever, chills high blood pressure skin rash, hives unusual swelling vomiting Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): anxious, nervous, tremor diarrhea [nationwidechildrens.org]

    Common side effects may include: nervousness; headache; dizziness, drowsiness; nausea, diarrhea, upset stomach, dry mouth; tired feeling; or sleep problem (insomnia). This is not a complete list of side effects and others may occur. [insiderx.com]

    Common side effects of Metaproterenol include: nervousness, headache, dizziness, drowsiness, nausea, diarrhea, upset stomach, dry mouth, tiredness, and sleep problem (insomnia) Serious side effects of Metaproterenol include: hives, difficulty breathing [rxlist.com]

Cardiovascular

  • Tachycardia

    SentidoA bronchodilator ( trade name Alupent) used to treat asthma and emphysema and other lung conditions; available in oral or inhalant forms ; side effects include tachycardia and shakiness .Sinónimo metaproterenol General broncodilatador A drug that [hyperdic.net]

    Adverse Reactions: Tachycardia, nervousness, tremor, headache, dizziness, GI upset, hypertension, paradoxical bronchospasm, cough, bad taste. How Supplied: Inh soln, tabs, syrup—contact supplier. [mycme.com]

  • Heart Disease

    […] rate medicines for heart disease or blood pressure pimozide sertindole stimulants This list may not describe all possible interactions. [my.clevelandclinic.org]

  • Hypertension

    Adverse Reactions: Tachycardia, nervousness, tremor, headache, dizziness, GI upset, hypertension, paradoxical bronchospasm, cough, bad taste. How Supplied: Inh soln, tabs, syrup—contact supplier. [mycme.com]

    Hypertension. Cardiovascular disease. CHF. Hyperthyroidism. Diabetes. Seizure disorders. Pregnancy (Cat.C). Nursing mothers. See Also: Metaproterenol Sulfate Syrup Classification: Beta-2 agonist. [empr.com]

  • Hypotension

    MAOIs may potentiate hypotensive effects. Beta blockers may antagonize metaproterenol. Pregnancy safety: Category C. Monitor vital signs for hypotension and tachycardia. Use with caution in patients with coronary artery disease and diabetes mellitus. [eilat.sci.brooklyn.cuny.edu]

    However, the hypotensive effect of isoproterenol was somewhat greater than that of metaproterenol. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. [onlinelibrary.wiley.com]

    Absorption 3% (oral bioavailability of 40%) Toxicity Symptoms of overdose include angina, hypertension or hypotension, arrhythmias, nervousness, headache, tremor, dry mouth, palpitation, nausea, dizziness, fatigue, malaise and insomnia. [druglib.com]

    Report tachycardia and hypotension. Patient & Family Education Report failure to respond to usual dose. Drug may have shorter duration of action after long-term use. [robholland.com]

    Nervousness 54 4.8 Gastrointestinal Nausea 15 1.3 Musculoskeletal Tremor 18 1.6 OVERDOSAGE The expected symptoms with overdosage are those of excessive beta stimulation and/or any of the symptoms listed under ADVERSE REACTIONS, e.g., angina, hypertension or hypotension [dailymed.nlm.nih.gov]

Skin

  • Flushing

    Restlessness, apprehension Palpitations Tachycardia Dysrhythmias Decreased blood pressure Coughing Facial flushing Diaphoresis Other svmpathomimetics may exacerbate adverse cardiovascular effects. MAOIs may potentiate hypotensive effects. [eilat.sci.brooklyn.cuny.edu]

    Be alert for signs of hyperglycemia, including confusion, drowsiness, flushed/dry skin, fruit-like breath odor, rapid/deep breathing, polyuria, loss of appetite, and unusual thirst. [fadavispt.mhmedical.com]

    Entries for 31 newly FDA-approved drugs provide the most current drug information available.Extensively updated IV content includes IV compatibilities, expanded rates of infusion, reconstitutions, drip rates, test doses, flushing, and incompatibilities [books.google.ro]

  • Sweating

    […] joint pain loss of appetite muscle aches and pains nausea nervousness pounding in the ears puffiness of the face and fingers runny nose shivering slow or fast heartbeat sore throat sweating swelling trouble sleeping unusual tiredness or weakness vomiting [mayoclinic.org]

    Rare: Blurred vision, dizziness, fainting, headache, fever, chills, cough, joint pains, increased sweating, diarrhoea, loss of appetite, nausea, heartburn, pharyngitis, insomnia, chest pain. Interaction : Acebutolol: Antagonism. [pediatriconcall.com]

    […] pressure skin rash, hives unusual swelling vomiting Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): anxious, nervous, tremor diarrhea headache increased sweating [nationwidechildrens.org]

  • Increased Sweating

    sweating joint pain loss of appetite muscle aches and pains nausea nervousness pounding in the ears puffiness of the face and fingers runny nose shivering slow or fast heartbeat sore throat sweating swelling trouble sleeping unusual tiredness or weakness [mayoclinic.org]

    Rare: Blurred vision, dizziness, fainting, headache, fever, chills, cough, joint pains, increased sweating, diarrhoea, loss of appetite, nausea, heartburn, pharyngitis, insomnia, chest pain. Interaction : Acebutolol: Antagonism. [pediatriconcall.com]

  • Skin Rash

    Side effects that you should report to your doctor or health care professional as soon as possible: blurred vision breathing problems dizziness, drowsiness fast, irregular heart rate, chest pain fever, chills high blood pressure skin rash, hives unusual [nationwidechildrens.org]

    Side effects that you should report to your doctor or health care professional as soon as possible: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue blurred vision breathing problems chest pain dizziness fast, [mychart.geisinger.org]

  • Pruritus

    […] heart rate Urinary tract infection Dysuria (painful urination) Urinary retention Increased diaphoresis (sweating) Chills Hyperactivity Restlessness Trembling Anxiety Agitation Depression Abnormal behavior Lymphadenopathy (swollen lymph nodes) Ocular pruritus [rxlist.com]

    146 tachycardia, 146 tremor, 146 headache, 146 palpitations, 146 nausea, 146 GI distress, 146 dizziness, 146 asthma exacerbation, 146 insomnia, 146 fatigue, 146 diarrhea, 146 bad taste, 146 vomiting, 146 drowsiness, 146 syncope, 146 hypertension, 146 pruritus [drugs.com]

    3.6 dizziness / Early / 2.4-2.4 insomnia / Early / 1.8-1.8 fatigue / Early / 1.4-1.4 diarrhea / Early / 1.2-1.2 dysgeusia / Early / 0.8-0.8 vomiting / Early / 0.8-0.8 drowsiness / Early / 0.6-0.6 syncope / Early / 0.4-0.4 xerostomia / Early / 0.4-0.4 pruritus [pdr.net]

Neurologic

  • Headache

    In addition, warned of possible S/E such as vertigo, headache, nervousness, dry and irritated throat, vomiting, nausea, dry mouth, etc. [nurseteachings.com]

    Adverse Reactions: Tachycardia, nervousness, tremor, headache, dizziness, GI upset, hypertension, paradoxical bronchospasm, cough, bad taste. How Supplied: Inh soln, tabs, syrup—contact supplier. [mycme.com]

  • Tremor

    In general, the individual tremor response was proportional to the extent by which a patient's basal tremor exceeded the minimal basal tremor for the group as a whole. [ncbi.nlm.nih.gov]

    Adverse Reactions: Tachycardia, nervousness, tremor, headache, dizziness, GI upset, hypertension, paradoxical bronchospasm, cough, bad taste. How Supplied: Inh soln, tabs, syrup—contact supplier. [mycme.com]

  • Seizure

    Seizure disorders. Pregnancy (Cat.C). Nursing mothers. See Also: Metaproterenol Inh Soln Metaproterenol Sulfate Tablets Pharmacological Class: Beta-2 agonist. Interactions: Avoid other aerosol β-agonists. [mycme.com]

    Seizure disorders. Pregnancy (Cat.C). Nursing mothers. See Also: Metaproterenol Sulfate Syrup Classification: Beta-2 agonist. Metaproterenol Sulfate Syrup Interactions: Avoid other aerosol β-agonists. [empr.com]

    Seizure disorders. Pregnancy (Cat.C). Nursing mothers. Pharmacologic Class: Beta-2 agonist. Interactions: Avoid other aerosol β-agonists. Potentiated by sympathomimetics, tricyclics, MAOIs. [pulmonologyadvisor.com]

  • Agitation

    […] reduced blood flow to heart muscles) Myocardial infarction (heart attack) Increased fetal heart rate Urinary tract infection Dysuria (painful urination) Urinary retention Increased diaphoresis (sweating) Chills Hyperactivity Restlessness Trembling Anxiety Agitation [rxlist.com]

  • Asthenia

    Spasms Pain in extremities Neck pain Migraine Central nervous system stimulation Paresthesia (prickling sensation) Peripheral edema Articular rheumatism (rheumatism in joints) Muscular stiffness and rigidity Muscle cramps Myositis (muscle inflammation) Asthenia [rxlist.com]

Treatment

The chronotropic effect of metaproterenol was greater than that of albuterol at 1 to 1 1/2 hours postdose on treatment days 1 and 28. [ncbi.nlm.nih.gov]

The usual adult dose is one vial per nebulization treatment. Usually, treatment need not be repeated more often than every four hours to relieve acute attacks of bronchospasm. [mstcparamedic.pbworks.com]

Prognosis

Generally, the prognosis for a patient with asthma is good. Exposure to allergens found on farms may protect against asthma symptoms. [medicinenet.com]

Epidemiology

Epidemiology and causes of preterm birth. Lancet 2008; 371: 75-84. Husslein P, et al. Atosiban versus usual care for the management of preterm labor. J Perinatal Med 2007; 35: 305-13. Nin: Consensus Development conference statement. [medigraphic.com]

Prevention

Abstract The effectiveness of inhaled versus oral metaproterenol in preventing exercise-induced asthma (EIA) was studied. [ncbi.nlm.nih.gov]

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. [drugs.com]

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