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Methyl Ethyl Ketone Poisoning

Mek Toxicity


Presentation

  • Esophageal mucosal oedema (grading 1 Zargar’s score) and several gastric necrotic areas (grading 3a) were present. The duodenum revealed few scattered superficial erosions.[flore.unifi.it]
  • Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a poison center or doctor. P308 P311 :If exposed or concerned: Call a poison center or doctor. P390 :Absorb spillage to prevent material damage.[tcichemicals.com]
  • The panel's delisting petition presented extensive information on MEK's potential health and environmental effects, environmental releases, and resulting ambient air concentrations.[americanchemistry.com]
  • Some of the major suppliers present in the value chain include Xilan Chemicals, Sigma-Aldrich, Sherwin-Williams, Wicks Aircraft Supply, and LP Chemicals.[grandviewresearch.com]
  • 【Eyes】 First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.[chemicalbook.com]
Physician
  • IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop.[chemicalbook.com]
  • If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital.[conestogafuels.com]
  • FIRST AID - IF SWALLOWED, do not induce vomiting, immediately call your poison control center, hospital emergency room or physician immediately for instructions.[kleanstrip.com]
Fatigue
  • The effects may be headaches, dizziness, fatigue, narcosis (acts like a narcotic), nausea, vomiting, and cause you to pass out. Methyl ethyl ketone vapour irritates the eyes, nose, and throat. Prolonged contact with the skin will cause irritation.[npi.gov.au]
Vomiting
  • 【Vapor Density】 6.08 First Aid Measures Back to Contents 【Ingestion】 DO NOT INDUCE VOMITING.[chemicalbook.com]
  • INGESTION : DO NOT INDUCE VOMITING. Volatile chemicals have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems.[conestogafuels.com]
  • DO NOT INDUCE VOMITING. Transport the victim IMMEDIATELY to a hospital.[cameochemicals.noaa.gov]
  • If vomiting occurs naturally, have victim lean forward to reduce risk of aspiration. Have victim rinse mouth with water again. Immediately call a Poison Centre or doctor.[ccohs.ca]
  • FIRST AID - IF SWALLOWED, do not induce vomiting, immediately call your poison control center, hospital emergency room or physician immediately for instructions.[kleanstrip.com]
Nausea
  • Symptoms of this include: Irritation to the nose and/or throat Headaches Dizziness Drowsiness Confusion Nausea If there is a high level of exposure to MEK, a person may faint, blackout or become unconscious.[cllegal.co.uk]
  • Symptoms of MEK Solvent poisoning when breathed in or swallowed: Irritation to the nose and throat Dizziness Headaches Nausea Drowsiness Confusion Exposure to high levels of MEK can result in fainting and unconsciousness If drawn into the lungs, it can[cuteinjury.co.uk]
  • The effects may be headaches, dizziness, fatigue, narcosis (acts like a narcotic), nausea, vomiting, and cause you to pass out. Methyl ethyl ketone vapour irritates the eyes, nose, and throat. Prolonged contact with the skin will cause irritation.[npi.gov.au]
  • Vapor irritates eyes, nose, and throat; can cause headache, dizziness, nausea, weakness, and loss of consciousness. (USCG, 1999) Reactivity Profile ETHYL METHYL KETONE is explosive in the form of vapor when exposed to heat, flame or sparks.[conestogafuels.com]
  • Symptoms may include headache, nausea, dizziness, drowsiness and confusion. A severe exposure can cause unconsciousness. Skin Contact: May cause mild irritation. Can be absorbed through the skin, but harmful effects are not expected.[ccohs.ca]
Tooth Discoloration
  • ., skin or tooth discoloration). The SMCLs are listed in 310 CMR 22.00.[mass.gov]
Blurred Vision
  • Novel agents that target different cellular pathways have been related to a wide spectrum of ophthalmologic toxicities that can range from mild to severe, and include conjunctivitis, blurred vision, keratitis and optic neuritis, among others.[ncbi.nlm.nih.gov]
Dermatitis
  • If an individual’s skin is exposed to the liquid frequently over a long period of time (which could be weeks, months or years – depending on the circumstances), dermatitis or very dry, chapped, itchy skin could occur.[cllegal.co.uk]
  • High exposure over long periods of time can cause dermatitis or very dry, chapped and itchy skin. MEK can also cause eye irritation, either by direct contact with liquid MEK or through vapour in the air.[cuteinjury.co.uk]
  • Effects of Long-Term (Chronic) Exposure: Can cause dry, red, cracked skin (dermatitis) following skin contact. May harm the nervous system. Conclusions cannot be drawn from the limited studies available. Carcinogenicity: Not known to cause cancer.[ccohs.ca]
Headache
  • Symptoms of this include: Irritation to the nose and/or throat Headaches Dizziness Drowsiness Confusion Nausea If there is a high level of exposure to MEK, a person may faint, blackout or become unconscious.[cllegal.co.uk]
  • Symptoms of MEK Solvent poisoning when breathed in or swallowed: Irritation to the nose and throat Dizziness Headaches Nausea Drowsiness Confusion Exposure to high levels of MEK can result in fainting and unconsciousness If drawn into the lungs, it can[cuteinjury.co.uk]
  • The effects may be headaches, dizziness, fatigue, narcosis (acts like a narcotic), nausea, vomiting, and cause you to pass out. Methyl ethyl ketone vapour irritates the eyes, nose, and throat. Prolonged contact with the skin will cause irritation.[npi.gov.au]
  • Vapor irritates eyes, nose, and throat; can cause headache, dizziness, nausea, weakness, and loss of consciousness. (USCG, 1999) Reactivity Profile ETHYL METHYL KETONE is explosive in the form of vapor when exposed to heat, flame or sparks.[conestogafuels.com]
  • Symptoms may include headache, nausea, dizziness, drowsiness and confusion. A severe exposure can cause unconsciousness. Skin Contact: May cause mild irritation. Can be absorbed through the skin, but harmful effects are not expected.[ccohs.ca]
Convulsions
  • If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital.[chemicalbook.com]

Workup

Giardia Lamblia
  • Additional Resources for Massachusetts Maximum Contaminant Levels - Radionuclides Massachusetts Maximum Contaminant Levels - Biologicals Biologicals Substance CASRN MMCL Cryptosporidium N/A Treatment Technique E. coli N/A 310 CMR 22.05 Giardia lamblia[mass.gov]

Treatment

  • N/A Treatment Technique Heterotrophic plate count N/A Treatment Technique Legionella N/A Treatment Technique Turbidity N/A Treatment Technique Viruses (enteric) N/A Treatment Technique Total coliforms N/A Indicator used in tiered monitoring protocol[mass.gov]
  • Many classes of anticancer therapy, including chemotherapeutic agents, hormonal and molecular targeted treatments, can produce ocular toxicity.[ncbi.nlm.nih.gov]
  • The surgeon decided for non-surgical treatment of pneumobilia and gastric injuries. The patient underwent orotracheal intubation and was transferred to an intensive care unit. Two days later, endoscopic examination was performed.[flore.unifi.it]
  • If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. 【Eyes】 First check the victim for contact lenses and remove if present.[chemicalbook.com]
  • If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION : IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.[conestogafuels.com]

Prevention

  • 【UN (DOT)】 2550 Exposure Controls/Personal Protection Back to Contents 【Personal Protection】 Wear appropriate clothing to prevent any reasonable probability of skin contact. Wear eye protection to prevent any possibility of eye contact.[chemicalbook.com]
  • Prevent entry into waterways, sewers, basements or confined areas. DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST. (ERG, 2016) Protective Clothing Skin: Wear appropriate personal protective clothing to prevent skin contact.[cameochemicals.noaa.gov]
  • P390 :Absorb spillage to prevent material damage. P403 P233 :Store in a well-ventilated place. Keep container tightly closed. P405 :Store locked up. P406 :Store in corrosive resistant bottle or metal container with a resistant inner liner.[tcichemicals.com]
  • Can MEK Poisoning be Prevented? There are a number of safety measures that can be implemented to limit any exposure to MEK. MEK should be kept away from any heat or sources of ignition. Any vapour emissions should be avoided if possible.[cuteinjury.co.uk]
  • (AAR, 2003) Protective Clothing Skin : Wear appropriate personal protective clothing to prevent skin contact. Eyes : Wear appropriate eye protection to prevent eye contact.[conestogafuels.com]

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