Presentation
We present an interesting case of salicylism arising from the use of methyl salicylate as part of a herbal skin cream for the treatment of psoriasis. [ncbi.nlm.nih.gov]
They also reported on the other things present in hemp seed oil, such as cannabidiol, ?-Sitosterol, tocopherols, and terpenes and terpenoids. [healthyhempoil.com]
Entire Body System
- Gastric Lavage
lavage ) If the poisoning occurred through skin exposure, the person may receive: Washing (irrigation) of the skin, perhaps every few hours for several days Antibiotic ointment (after skin irrigation) Surgery to remove burned skin (debridement) If the [nlm.nih.gov]
lavage for elimination of compound from the stomach (irrigation using special solutions) Medically manage symptoms and provide breathing support, if necessary Administer activated charcoal to avoid absorbance of compound in the body Administer laxatives [dovemed.com]
Gastric lavage if the patient has ingested more than 500 mg/kg body weight salicylate within one hour. Aggressive rehydration. Have a low threshold to give glucose, as intracellular glucose depletion may not be reflected in the blood glucose level. [patient.co.uk]
Respiratoric
- Hyperpnea
The patient developed tinnitus followed by hyperpnea, vomiting, diaphoresis, fever, and CNS disturbance (wintergreen oil in liquid form is a highly lipid soluble). [drugs.com]
Ears
- Tinnitus
The presence of tinnitus, vomiting, tachypnoea and typical acid/base disturbance allowed a diagnosis of salicylate toxicity to be made. [ncbi.nlm.nih.gov]
Nausea, vomiting, diaphoresis, and tinnitus [12] are the earliest signs and symptoms of salicylate toxicity. Other early symptoms and signs are vertigo, hyperventilation, tachycardia, and hyperactivity. [emedicine.medscape.com]
Mild salicylate toxicity, which can occur from high dosage therapy, has symptoms that include headache, dizziness, tinnitus, deafness, nausea, vomiting, and acid-base disturbances. [medical-dictionary.thefreedictionary.com]
Clinical grading: Mild (nausea, vomiting, tinnitus). Moderate (hyperventilation and confusion). Serious (hallucinations, seizures, coma, cerebral oedema or pulmonary oedema). [patient.co.uk]
Workup
(See Presentation and Workup .) Phase 1 of the toxicity is characterized by hyperventilation resulting from direct respiratory center stimulation, leading to respiratory alkalosis and compensatory alkaluria. [emedicine.medscape.com]
Treatment
RESULTS: No plasma salicylate was detected after buccal treatment phase. Relative bioavailability for the low-dose treatment was 0.5 compared to oil of wintergreen. [ncbi.nlm.nih.gov]
It ans its derivatives are used in the treatment of hyperkeratotic, dandruff, ichthyosis and psoriasis as well as in the treatment of fungal skin infections such as tinea. [chemicalland21.com]
Prognosis
The prognosis of Methyl Salicylate Overdose is dependent on the amount of compound consumed, time between overdose and treatment, severity of the symptoms, as well as general health status of the patient In many cases, the individual can recover from [dovemed.com]
Activated charcoal Laxative Tube through the mouth into the stomach if vomiting contains blood Breathing support, including tube through the mouth into the lungs and connected to a breathing machine (ventilator) Kidney dialysis in serious cases Outlook (Prognosis [mountsinai.org]
Prevention
Office Of Prevention, Pesticides And Toxic Substances, Reregistration eligibility decision (red) : Methyl salicylate. (2005). http://www.epa.gov/oppsrrd1/REDs/methyl_salicylate_red.pdf ▲7. Overman, D. [reptox.cnesst.gouv.qc.ca]
Treatment of salicylic acid with phenol gives phenyl salicylate, which is used for sunburn creams and enteric-coated pills and to make salicylanilide for use as a fungicide and mildew preventive. Salicylic acid… Read More [britannica.com]
Solid NaOH or dissolved is very corrosive and any skin contact with it or swallowing should be prevented. [scholieren.com]
It is one of the active ingredients in the drugs used in the prevention and reduction of bad breath, gingivitis and plaque, particularly in Listerine. Anti-inflammatory: Methyl salicylate shows anti-inflammatory activity. [ayurvedicoils.com]