We present an interesting case of salicylism arising from the use of methyl salicylate as part of a herbal skin cream for the treatment of psoriasis. [ncbi.nlm.nih.gov]

• Pain

  It is a counterirritant that relieves the pain by first cooling and then warming the skin. These alternate feelings divert the feeling of pain in muscles, joints and bones. [ayurvedicoils.com]

  Pain intensity was assessed on a 100-mm visual analog scale while at rest and with movement for 12 hours after patch application. The primary efficacy end point was the summed pain intensity difference score through 8 hours (SPID8) with movement. [ncbi.nlm.nih.gov]

  Pain Quiz: Test Your IQ of Pain Is pain all in the brain? Take the Pain Quiz to learn everything you've ever wanted to know about the unpleasant sensation we... Back Pain: Find Relief, Treat Your Back Pain Back pain conditions are very common. [medicinenet.com]

  Adverse events were rare in studies of acute pain and poorly reported in those of chronic pain. Efficacy estimates for rubefacients are unreliable owing to a lack of good clinical trials. [doi.org]

• Inflammation

  Abstract As an important part of non steroids anti-inflammation drug (NSAIDs), salicylate has developed from natural substance salicylic acid to natrium salicylicum, to aspirin. [ncbi.nlm.nih.gov]

  Some of the therapeutic effect described comes from counter-irritation that affects the original inflammation. [adv-bio.com]

  Tests that may be done include: Blood and urine tests Chest x-ray ECG (electrocardiogram, or heart tracing) Treatment may include: Fluids through a vein (by IV) Medicine to reverse stomach inflammation and bleeding, breathing problems, and other symptoms [nlm.nih.gov]

• Fever

  It relieves pain, reduces inflammation, and reduces fever. [encyclopedia.com]

  Collapse Low blood pressure LUNGS AND AIRWAYS Difficulty breathing No breathing Rapid breathing NERVOUS SYSTEM Agitation, confusion, hallucinations Coma (decreased level of consciousness and lack of responsiveness) Deafness Dizziness Drowsiness Headache Fever [nlm.nih.gov]

  The salicylic acid has as asperin anti-inflammatory, anti-fever, and pain killing properties. Salicylic acid is produced by various plants among others the willow tree. [scholieren.com]

• Gastric Lavage

  lavage ) If the poisoning occurred through skin exposure, the person may receive: Washing (irrigation) of the skin, perhaps every few hours for several days Antibiotic ointment (after skin irrigation) Surgery to remove burned skin (debridement) If the [nlm.nih.gov]

  lavage for elimination of compound from the stomach (irrigation using special solutions) Medically manage symptoms and provide breathing support, if necessary Administer activated charcoal to avoid absorbance of compound in the body Administer laxatives [dovemed.com]

  Gastric lavage if the patient has ingested more than 500 mg/kg body weight salicylate within one hour. Aggressive rehydration. Have a low threshold to give glucose, as intracellular glucose depletion may not be reflected in the blood glucose level. [patient.co.uk]

• Asymptomatic

  The sample should be taken at least two hours (symptomatic patients) or four hours (asymptomatic patients) following ingestion, as it may take several hours for peak plasma concentrations to occur. [patient.co.uk]

• Dyspnea

  […] child LDLo oral 228mg/kg (228mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING LUNGS, THORAX, OR RESPIRATION: DYSPNEA American Journal of Diseases of Children. [chem.nlm.nih.gov]

  Human systemic effects by ingestion: flaccid paralysis without anesthesia, general anesthesia, dyspnea, nausea, vomiting, and respiratory stimulation. Experimental reproductive effects. A severe skin and eye irritant. [chemicalbook.com]

• Hyperpnea

  The patient developed tinnitus followed by hyperpnea, vomiting, diaphoresis, fever, and CNS disturbance (wintergreen oil in liquid form is a highly lipid soluble). [drugs.com]

• Vomiting

  DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. [cameochemicals.noaa.gov]

  […] child LDLo oral 228mg/kg (228mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING LUNGS, THORAX, OR RESPIRATION: DYSPNEA American Journal of Diseases of Children. [chem.nlm.nih.gov]

  The presence of tinnitus, vomiting, tachypnoea and typical acid/base disturbance allowed a diagnosis of salicylate toxicity to be made. [ncbi.nlm.nih.gov]

  Do NOT induce vomiting. P302+P352-IF ON SKIN: Wash with plenty of water/. P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. [fishersci.es]

  Difficulty breathing No breathing Rapid breathing NERVOUS SYSTEM Agitation, confusion, hallucinations Coma (decreased level of consciousness and lack of responsiveness) Deafness Dizziness Drowsiness Headache Fever Seizures STOMACH AND INTESTINES Nausea Vomiting [nlm.nih.gov]

• Nausea

  […] child LDLo oral 228mg/kg (228mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING LUNGS, THORAX, OR RESPIRATION: DYSPNEA American Journal of Diseases of Children. [chem.nlm.nih.gov]

  健康ハザード Methyl salicylate is a highly toxic compound.The toxic symptoms in humans include nausea, vomiting, gastritis, diarrhea, respiratorystimulation, labored breathing, pulmonaryedema, convulsions, and coma. [chemicalbook.com]

  AIRWAYS Difficulty breathing No breathing Rapid breathing NERVOUS SYSTEM Agitation, confusion, hallucinations Coma (decreased level of consciousness and lack of responsiveness) Deafness Dizziness Drowsiness Headache Fever Seizures STOMACH AND INTESTINES Nausea [nlm.nih.gov]

  Clinical grading: Mild (nausea, vomiting, tinnitus). Moderate (hyperventilation and confusion). Serious (hallucinations, seizures, coma, cerebral oedema or pulmonary oedema). [patient.co.uk]

• Diarrhea

  Vol. 28, Pg. 475, 1953. dog LD50 oral 2100mg/kg (2100mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Food and Cosmetics Toxicology. [chem.nlm.nih.gov]

  健康ハザード Methyl salicylate is a highly toxic compound.The toxic symptoms in humans include nausea, vomiting, gastritis, diarrhea, respiratorystimulation, labored breathing, pulmonaryedema, convulsions, and coma. [chemicalbook.com]

• Hypotension

  The signs and symptoms of Methyl Salicylate Overdose may include Breathing difficulties or an absence of breathing Nausea, vomiting (sometimes, blood in vomit); GI bleeding Swelling in the throat Decreased blood pressure (hypotension) Feeling drowsy and [dovemed.com]

• Musculoskeletal Pain

  This is thought to mask the underlying musculoskeletal pain and discomfort. [drugbank.ca]

  Pain Management: Musculoskeletal Pain Natural menopause is the permanent ending of menstruation that is not brought on by any type of medical treatment. For women... [medicinenet.com]

• Tinnitus

  The presence of tinnitus, vomiting, tachypnoea and typical acid/base disturbance allowed a diagnosis of salicylate toxicity to be made. [ncbi.nlm.nih.gov]

  Nausea, vomiting, diaphoresis, and tinnitus [12] are the earliest signs and symptoms of salicylate toxicity. Other early symptoms and signs are vertigo, hyperventilation, tachycardia, and hyperactivity. [emedicine.medscape.com]

  Clinical grading: Mild (nausea, vomiting, tinnitus). Moderate (hyperventilation and confusion). Serious (hallucinations, seizures, coma, cerebral oedema or pulmonary oedema). [patient.co.uk]

  Mild salicylate toxicity, which can occur from high dosage therapy, has symptoms that include headache, dizziness, tinnitus, deafness, nausea, vomiting, and acid-base disturbances. [medical-dictionary.thefreedictionary.com]

• Irritability

  IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. [cameochemicals.noaa.gov]

  Methyl salicylate in topical analgesic preparations may cause irritant or allergic contact dermatitis and anaphylactic reactions. Physicians should fully appreciate the potential dangers from topical preparations containing methyl salicylate. [ncbi.nlm.nih.gov]

  Ingredients such as menthol, methyl salicylate and camphor are called counter-irritants because they produce irritation in one part of the body to help relieve irritation in another. [ruba535.com]

• Headache

  Headache after administration of electroconvulsive therapy (ECT) is common, affecting approximately half of patients treated. [ncbi.nlm.nih.gov]

  Wintergreen oil is sometimes used for muscle pain and headaches. Some of the therapeutic effect described comes from counter-irritation that affects the original inflammation. [adv-bio.com]

  BLOOD Collapse Low blood pressure LUNGS AND AIRWAYS Difficulty breathing No breathing Rapid breathing NERVOUS SYSTEM Agitation, confusion, hallucinations Coma (decreased level of consciousness and lack of responsiveness) Deafness Dizziness Drowsiness Headache [nlm.nih.gov]

(See Presentation and Workup .) Phase 1 of the toxicity is characterized by hyperventilation resulting from direct respiratory center stimulation, leading to respiratory alkalosis and compensatory alkaluria. [emedicine.medscape.com]

RESULTS: No plasma salicylate was detected after buccal treatment phase. Relative bioavailability for the low-dose treatment was 0.5 compared to oil of wintergreen. [ncbi.nlm.nih.gov]

The prognosis of Methyl Salicylate Overdose is dependent on the amount of compound consumed, time between overdose and treatment, severity of the symptoms, as well as general health status of the patient In many cases, the individual can recover from [dovemed.com]

Activated charcoal Laxative Tube through the mouth into the stomach if vomiting contains blood Breathing support, including tube through the mouth into the lungs and connected to a breathing machine (ventilator) Kidney dialysis in serious cases Outlook (Prognosis [mountsinai.org]

It is one of the active ingredients in the drugs used in the prevention and reduction of bad breath, gingivitis and plaque, particularly in Listerine. Anti-inflammatory: Methyl salicylate shows anti-inflammatory activity. [ayurvedicoils.com]

Be the first video Your name here Important information Legal Disclaimer Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition. [amazon.com]

Treatment of salicylic acid with phenol gives phenyl salicylate, which is used for sunburn creams and enteric-coated pills and to make salicylanilide for use as a fungicide and mildew preventive. Salicylic acid… Read More [britannica.com]

Office Of Prevention, Pesticides And Toxic Substances, Reregistration eligibility decision (red) : Methyl salicylate. (2005). http://www.epa.gov/oppsrrd1/REDs/methyl_salicylate_red.pdf ▲7. Overman, D. [reptox.cnesst.gouv.qc.ca]