We present an interesting case of salicylism arising from the use of methyl salicylate as part of a herbal skin cream for the treatment of psoriasis. [ncbi.nlm.nih.gov]

• Gastric Lavage

  lavage for elimination of compound from the stomach (irrigation using special solutions) Medically manage symptoms and provide breathing support, if necessary Administer activated charcoal to avoid absorbance of compound in the body Administer laxatives [dovemed.com]

  lavage ) If the poisoning occurred through skin exposure, the person may receive: Washing (irrigation) of the skin, perhaps every few hours for several days Antibiotic ointment (after skin irrigation) Surgery to remove burned skin (debridement) If the [nlm.nih.gov]

  Gastric lavage if the patient has ingested more than 500 mg/kg body weight salicylate within one hour. Aggressive rehydration. Have a low threshold to give glucose, as intracellular glucose depletion may not be reflected in the blood glucose level. [patient.info]

• Epilepsy

  Associated Conditions Pain NOS Postherpetic Neuralgia Minor aches Partial onset seizure Epilepsy Pharmacodynamics Methyl salicylate relieve musculoskeletal pain in the muscles, joints, and tendons by causing irritation and reddening of the skin due to [drugbank.ca]

• Hunting

  and Hunt, M. D. 1996. Systemic acquired resistance. Plant Cell Physiol. 37:762-769. Google Scholar Shimoda, T., Takabayashi, J., Ashira, W., and Takafuji, A. 1997. [doi.org]

• Hyperpnea

  The patient developed tinnitus followed by hyperpnea, vomiting, diaphoresis, fever, and CNS disturbance (wintergreen oil in liquid form is a highly lipid soluble). [drugs.com]

• Formication

  Now, methyl salicylate glycoside, a new derivative of salicylic acid, is modified with a -COOH group integrated one methyl radical into formic ether, and a -OH linked with a monosaccharide, a disaccharide or a trisaccharide unit by glycosidic linkage. [ncbi.nlm.nih.gov]

• Tinnitus

  The presence of tinnitus, vomiting, tachypnoea and typical acid/base disturbance allowed a diagnosis of salicylate toxicity to be made. [ncbi.nlm.nih.gov]

  Mild salicylate toxicity, which can occur from high dosage therapy, has symptoms that include headache, dizziness, tinnitus, deafness, nausea, vomiting, and acid-base disturbances. [medical-dictionary.thefreedictionary.com]

  Clinical grading: Mild (nausea, vomiting, tinnitus). Moderate (hyperventilation and confusion). Serious (hallucinations, seizures, coma, cerebral oedema or pulmonary oedema). [patient.info]

  Nausea, vomiting, diaphoresis, and tinnitus [12] are the earliest signs and symptoms of salicylate toxicity. Other early symptoms and signs are vertigo, hyperventilation, tachycardia, and hyperactivity. [emedicine.medscape.com]

• Hyperalgesia

  For most subjects, methyl salicylate produced a hyperalgesia to heating. Overall, the data suggest that methyl salicylate probably produces its sensory effects via stimulation and/or sensitization of a population of cutaneous nociceptors. [ncbi.nlm.nih.gov]

(See Presentation and Workup .) Phase 1 of the toxicity is characterized by hyperventilation resulting from direct respiratory center stimulation, leading to respiratory alkalosis and compensatory alkaluria. [emedicine.medscape.com]

RESULTS: No plasma salicylate was detected after buccal treatment phase. Relative bioavailability for the low-dose treatment was 0.5 compared to oil of wintergreen. [ncbi.nlm.nih.gov]

Tests that may be done include: Blood and urine tests Chest x-ray ECG (electrocardiogram, or heart tracing) Treatment may include: Fluids through a vein (by IV) Medicine to reverse stomach inflammation and bleeding, breathing problems, and other symptoms [nlm.nih.gov]

The prognosis of Methyl Salicylate Overdose is dependent on the amount of compound consumed, time between overdose and treatment, severity of the symptoms, as well as general health status of the patient In many cases, the individual can recover from [dovemed.com]

Activated charcoal Laxative Tube through the mouth into the stomach if vomiting contains blood Breathing support, including tube through the mouth into the lungs and connected to a breathing machine (ventilator) Kidney dialysis in serious cases Outlook (Prognosis [mountsinai.org]

KEY RESULTS: Treatment with MSL after the onset of arthritis significantly prevented the progression and development of rheumatoid arthritis (RA) in CIA mice without megascopic gastric mucosa damage. [ncbi.nlm.nih.gov]

Treatment of salicylic acid with phenol gives phenyl salicylate, which is used for sunburn creams and enteric-coated pills and to make salicylanilide for use as a fungicide and mildew preventive. Salicylic acid… Read More [britannica.com]

Be the first video Your name here Important information Legal Disclaimer Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition. [amazon.com]

You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. Take the container with you to the hospital, if possible. [nlm.nih.gov]