A case of repeated methylergonovine-induced spasm of a saphenous vein bypass graft in a 56-year-old man is presented. Prior to the operation, spasm was induced by methylergonovine in the stenosed right coronary artery. [ncbi.nlm.nih.gov]

Case 3 Patient presented to the headache clinic with a diagnosis of episodic migraine without aura which started 7 years ago. Episodic headache attacks lasting for 1–3 days occurring on average 5–6 times a month. [frontiersin.org]

Letter Kefzol (cefazolin) all presentations 2/28/2003 Eli Lilly and Company Letter Kefurox (cefuroxime) all presentations 2/28/2003 Eli Lilly and Company Letter Kemadrin (procyclidine hydrochloride) 6/6/2008 King Pharmaceuticals 800-776-3637 Letter from [johalimedical.com]

The following examples will further illustrate the present invention and enable others skilled in the art to understand it more completely. [google.com]

• Muscle Rigidity

  Monitor for evidence of serotonin toxicity (eg, mental status changes, autonomic instability, and neuromuscular hyperactivity) or neuroleptic malignant syndrome (eg, hyperthermia, muscle rigidity, autonomic dysfunction). Minor (0) [reference.medscape.com]

• Uterine Tenderness

  tenderness, maternal tachycardia, or fetal tachycardia. [journals.lww.com]

Breast-feeding Mothers should not breast-feed during treatment with methylergonovine maleate. Milk secreted during this period should be discarded. [americanregent.com]

Treatment for primary postpartum haemorrhage. Cochrane Database Syst Rev. 2007; 1:CD003249. [PubMed 17253486] g. Perinatal HIV Guidelines Working Group. [web.archive.org]

Treatment for primary postpartum haemorrhage. Cochrane Database Syst Rev. 2007; 1:CD003249. g. Perinatal HIV Guidelines Working Group. [drugs.com]

16836961 Stability of oral liquid preparations of methylergometrine. 2006 Aug 16964714 [Heart and freezer: about one case of hypereosinophilia and coronary spasm]. 2006 Aug 16922173 Improved migraine management in primary care: results of a patient treatment [drugs.ncats.io]

Review of the literature suggests that coronary artery spasm after transplantation is often associated with severe transplant coronary artery disease and may be associated with a poor prognosis. [ncbi.nlm.nih.gov]

[…] clinical symptoms of left-sided substernal chest pain, radiating to the left upper extremity, with associated shortness of breath, and electrocardiographic changes almost immediately after intramyometrial administration of Methergine suggest cardiac etiology [anesthesiology.pubs.asahq.org]

The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries. Anesth Analg. 2010 May 1;110(5):1368-73. Oyelese Y, Ananth CV. Postpartum hemorrhage: epidemiology, risk factors, and causes. [lupinpharmaceuticals.com]

These and other observations emphasize the importance of the physiological or pathophysiological state in determining the spectrum and intensity of effects produced in animals or patients. [web.archive.org]

[…] maleate (methergine) relieves postdural puncture headache in obstetric patients. 2005 Jan 15603581 The MFMU Cesarean Registry: uterine atony after primary cesarean delivery. 2005 Sep 16157111 The role of serendipity in drug discovery. 2006 17117615 Prevention [drugs.ncats.io]

Assessing preventability for obstetric hemorrhage. Am J Perinatol 2011;28:753–60. doi: 10.1055/s-0031-1280856 6. Westhoff G, Cotter AM, Tolosa JE. Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage. [journals.lww.com]

Evaluation/Desired Outcomes Contractions that maintain uterine tone and prevent postpartum hemorrhage. methylergonovine /meth·yl·er·go·no·vine/ ( meth″il-er″go-no´vēn ) an oxytocic, used as the maleate salt to prevent or combat postpartum or postabortion [medical-dictionary.thefreedictionary.com]

Methylergonovine is a semi-synthetic ergot alkaloid used for the prevention and control of postpartum haemorrhage. [biospectrumindia.com]

Intravenous injection of 5 IU oxytocin immediately after delivery of fetal anterior shoulder is the treatment of choice for prevention of PPH in patients with natural course of labor. [oadoi.org]