There were differing vascular patterns of presentation: 2 patients presented with small-vessel (lacunar) infarctions, whereas 1 patient presented with a large-vessel infarct. [ncbi.nlm.nih.gov]

• Collapse

  For shock, give massive doses over at least 10 minutes to prevent arrhythmias and circulatory collapse. [glowm.com]

  If you think you or someone else may have overdosed on: Methylprednisolone (Medrol), call your doctor or the Poison Control center (800) 222-1222 If someone collapses or isn't breathing after taking Methylprednisolone (Medrol), call 911 911 What to Expect [everydayhealth.com]

  If the victim has collapsed or is not breathing, call local emergency services at 911. [methylprednisolone.com]

  If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Keep all appointments with your doctor and the laboratory. [medlineplus.gov]

• Intravenous Administration

  We describe the development of acute hypokalemic paralysis in a middle-aged Caucasian man with recently diagnosed thyrotoxicosis and severe, active Graves' opthalmopathy who developed progressive flaccid paralysis 12 hours following intravenous administration [ncbi.nlm.nih.gov]

  The acetate is often prepared in long-acting forms while the water-soluble, rapid-acting succinate is suitable for intravenous administration and is used in the treatment of shock. methylprednisolone-21-dimethylaminoacetate a long-acting glucocorticoid [medical-dictionary.thefreedictionary.com]

  Furthermore, with regard to the testing of high or mega-doses of the steroid in SCI patients, there was already considerable clinical experience with the intraveneous administration of doses as high, or higher, than 30 mg/kg in several clinical studies [rehab.research.va.gov]

• Aspiration

  Glossary of Medical Terms Sarcoid: fleshy tumor.   Aspiration : withdrawal of fluid from the body by means of suction using an aspirator.  Lymphoma : malignant tumor of lymph nodes.  Giant cell arteritis: A serious disease characterized by inflammation [slideshare.net]

  It is also given to the female partner to reduce the risk of infection following aspiration of the follicles at the time of egg retrieval. [web.archive.org]

  […] systemic therapy) Respiratory Diseases • Symptomatic sarcoidosis • Berylliosis • Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy • Loeffler’s syndrome not manageable by other means • Aspiration [globalrph.com]

  Corticosteroids in treatment of aspiration-related acute respiratory distress syndrome: results of a retrospective cohort study. BMC Pulm Med. 2016 Feb 10;16:29. [PMC free article: PMC4748555] [PubMed: 26864571] 16. Alangari AA. [ncbi.nlm.nih.gov]

  Approximately 36 hours after your HCG injection, you will undergo aspiration of your follicles to obtain the eggs. This is done under ultrasound guidance using a specially designed needle. [rmami.com]

• Cardiomegaly

  Monitor therapy Test Interactions Decreased response to skin tests Adverse Reactions Frequency not defined: Cardiovascular: Bradycardia, cardiac arrest, cardiac arrhythmia, cardiac failure, cardiomegaly, circulatory shock, edema, embolism (fat), hypertension [drugs.com]

• Arthralgia

  Henoch-Schönlein purpura is an immunoglobulin A-mediated, small vascular inflammatory disease that can be associated with palpable purpura, arthralgia, abdominal pain, or nephritis. [ncbi.nlm.nih.gov]

  Transplantation, Kidney 1 4CompletedTreatment Relapsing Remitting Multiple Sclerosis (RRMS) 3 4CompletedTreatment Rheumatoid Arthritis 5 4CompletedTreatment Sarcopenia 1 4CompletedTreatment Sciatica 1 4CompletedTreatment Sepsis 1 4CompletedTreatment Arthralgia [drugbank.ca]

• Euphoria

  Adverse reactions CNS: headache, restlessness, nervousness, depression, euphoria, personality changes, psychoses, vertigo, paresthesias, insomnia, adhesive arachnoiditis, conus medullaris syndrome, increased intracranial pressure, seizures, meningitis [medical-dictionary.thefreedictionary.com]

  Adverse reactions CNS: euphoria, insomnia, psychotic behavior, pseudotumor cerebri, vertigo, headache, paresthesia, seizures. [glowm.com]

  […] corticosteroids to be effective in speeding the resolution of acute exacerbations of multiple sclerosis, they do not affect the ultimate outcome or natural history of the disease Psychic derangements may appear when corticosteroids used, ranging from euphoria [reference.medscape.com]

  Extreme mood changes: Tell your healthcare provider right away if you have some or all of the following symptoms... euphoria (intense feeling of happiness or joy) insomnia mood swings personality changes severe depression Stunted growth in children: Growth [rxwiki.com]

  […] shown corticosteroids to be effective in speeding the resolution of acute exacerbations of multiple sclerosis, they do not affect the outcome or natural history of the disease Psychic derangements may appear when corticosteroids are used, ranging from euphoria [rxlist.com]

• Withdrawn

  If after long-term therapy the drug is to be stopped, it is recommended that it be withdrawn gradually rather than abruptly. [rxlist.com]

  […] keloids, psoriatic plaques, alopecia areata, discoid lupus erythematosus, necrobiosis lipoidica diabeticorum, granuloma annulare d m unresponsive to topical therapy. c Rarely indicated for psoriasis † ; c if used, exacerbation may occur when the drug is withdrawn [drugs.com]

• Myelopathy

  Abstract HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an immune mediated myelopathy caused by the human T-lymphotropic virus type 1 (HTLV-1). The efficacy of treatments used for patients with HAM/TSP is uncertain. [ncbi.nlm.nih.gov]

  / Disseminated Sclerosis / Myelitis NOS / Neuritis / Optic Neuritis 1 4WithdrawnTreatment Pediatric Crohn's Disease 1 Not Available Active Not RecruitingPrevention Cervical Degenerative Disc Disease / Cervical Disc Herniation / Cervical Spondylotic Myelopathy [drugbank.ca]

I had my whole spine MRI, including the lumbar just recently, and over these years I've probably had the best workup done, as far Version: pfdsolmv10718 Supersedes: pfdsolmv10218 Page 2 of 28 SOLU-MEDROL ACT-O-VIAL 500 mg/4 mL The vial compartment with [its.ecnet.jp]

• Neutrophilia

  Hematologic side effects include leukocytosis and neutrophilia. [ncbi.nlm.nih.gov]

  […] activity and release of kinin from substrates. c Reduces fibroblast proliferation, collagen deposition, and subsequent scar tissue formation. c Stimulates erythroid cells of bone marrow, prolongs survival time of erythrocytes and platelets, and produces neutrophilia [drugs.com]

CONCLUSIONS: The combined treatment was more effective in reducing lumbar facet pain and improving the functional index than either treatment alone. This approach should be the preferred treatment. [ncbi.nlm.nih.gov]

longer treatment may be required. [drugs.com]

However, RHS has, per se, a poorer prognosis than idiopathic facial palsy (Bell's palsy). [ncbi.nlm.nih.gov]

Influence of high dose methylprednisolone therapy on prognosis of acute transverse myelitis in children.. 2005; 20(3): 190-192 Sorumlu Yazar: Müferet Ergüven, Türkiye [journalagent.com]

What This Study Adds: High doses of methylprednisolone therapy lead to less frequent stricture formation in grade IIb esophageal burns in children who ingested caustic substances and may improve prognosis. [pediatrics.aappublications.org]

[…] corticosteroids were used, with the question of ‘one dose of corticosteroids does not fit for all patients’ to remain a hot point of interest.14 In this retrospective study, we investigated the effect of 3-day methylprednisolone pulses (MPs) on the prognosis [jim.bmj.com]

High-dose methylprednisolone therapy should thus be considered for patients demonstrating ANA-positive agranulocytosis with an unknown etiology that is refractory to G-CSF treatment. [ncbi.nlm.nih.gov]

It is unclear whether this late onset case of meningitis is directly attributable to the contaminated steroid injection or arose from an unrelated etiology. [cdc.gov]

[…] and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran. [ncbi.nlm.nih.gov]

Discussion We describe epidemiologic and laboratory data from a multistate outbreak of fungal infections associated with injection of contaminated methylprednisolone acetate from a single compounding pharmacy. [nejm.org]

Vestibular neuronitis: epidemiological survey by questionnaire in Japan. Acta Otolaryngol Suppl 1993 ;503: 9 - 12 3. Ruttin B. Zur Differentialdiagnose der Labyrinth- und Hörnerverkrankungen. Z Ohrenheilkunde 1909 ;57: 327 - 333 4. Nylen CO. [doi.org]

Author information 1 a Section for Surgical Pathophysiology, Copenhagen University Hospital. 2 b The Lundbeck Foundation Centre for Fast-Track Hip and Knee Arthroplasty, Copenhagen. 3 c Physical Medicine & Rehabilitation Research-Copenhagen (PMR-C), Department [ncbi.nlm.nih.gov]

Dolhnikoff M, Mauad T, Bethlem EP, Carvalho CR (2007) Pathology and pathophysiology of pulmonary manifestations in leptospirosis. Braz J Infect Dis 11:142-148. [omicsonline.org]

SOME NEW NEUROPROTECTIVE OR NEURORESTORATIVE APPROACHES Novel Scavengers of ROS In view of the clear role of reactive oxygen or oxygen radical-induced LP in the pathophysiology of post-traumatic spinal cord degeneration, and the demonstrated benefits [rehab.research.va.gov]

[…] are distributed into milk and could suppress growth, interfere with endogenous glucocorticoid production, or cause other adverse effects in nursing infants. c d m Discontinue nursing or the drug. m Pediatric Use The effects of glucocorticoids on the pathophysiology [drugs.com]

However, the roles of corticosteroids and nonsteroidal anti-inflammatory drugs in PPS prevention remains unclear. This study aimed to determine whether the intraoperative use of single-dose methylprednisolone can effectively prevent PPS. [ncbi.nlm.nih.gov]

Lupron temporarily suppresses pituitary and ovarian hormone production and prevents ovulation from occurring prior to oocyte retrieval. [web.archive.org]

The short-term use of corticosteroids antepartum for the prevention of respiratory distress syndrome does not seem to pose a risk to the fetus or newborn infant. [drugs.com]