Simple Education 720 Videos | 125 Topics Topics: Aorta · Coronary arteries · PCSK9 Antagonists · Anti-Platelet Drugs Event: International Society of Cardiovacular Pharmacology Speakers: Juan Carlos Kaski Summary Management of Microvascular Angina - Presented [rutherfordmedicine.com]

This review briefly addresses the clinical presentation, mechanisms and management of patients with chronic primary stable MVA. [ncbi.nlm.nih.gov]

Finally, CYP2C19 PMs are present in 2–3% of Caucasians ( 21 ), whereas they are found in 11, 21, 23, 35 ). [physiology.org]

There is at present no known cure however a change in lifestyle is important. Patients should start following healthier diets which are low in saturated fats, and should participate in regular physical activities. [en.wikipedia.org]

• Atrial Septal Defect

  Left main coronary trunk compression by dilated main pulmonary artery in atrial septal defect. Report of three cases. J Thorac Cardiovasc Surg 104 : 449–452, 1992. PubMed ISI Google Scholar 11. [physiology.org]

• Rigor

  Based on these results, we rigorously diagnosed the condition of the patients and obtained accurate results with no contradictions. [physiology.org]

• Intravenous Administration

  administration of adenosine (0.14 µg/kg/min) or dipyridamole (0.84 mg/kg in 6 min). [ncbi.nlm.nih.gov]

• Formication

  Formic acid was added to adjust pH to 5.5 and then equal amount of ethyl acetate was applied and centrifuged at 2,000 rpm for 10 min at room temperature. The upper phase was collected and dried up again. [physiology.org]

• Suggestibility

  In some MVA patients, both the early appearance of ECG abnormalities and/or angina during the stress test and the lack of response to sublingual nitrate administration often suggests a microvascular origin of symptoms. [ncbi.nlm.nih.gov]

  However, the low rate of increase in the MVA PM group suggests dysfunctional EET upregulation. [physiology.org]

  Reviews Determinants of long-term clinical outcomes in patients with angina but without obstructive coronary artery disease: a systematic review and meta-analysis 24 April 2018 - Publisher: European Heart Journal Review of data from 54 studies (n=35,039) suggests [evidence.nhs.uk]

  Older people are more at risk to develop this condition, and there is some evidence that suggests that there are genetic mutations that predispose to the syndrome. [3] Women are more prone to this condition than men, as well as those who have a history [en.wikipedia.org]

• Ischemic Changes

  All MVA cases experiencing chest pain and ischemic changes in the electrocardiogram (ECG) in the exercise stress test underwent cardiac catheterization. [physiology.org]

[…] part of the treatment is regularly visiting the doctor and repeating the tests to make sure the condition was taken care of in full. [en.wikipedia.org]

Read Summary - More: Systematic Reviews The Effect of IV Cangrelor and Oral Ticagrelor Study Source: UK Clinical Trials Gateway - UKCTG - 05 April 2016 Coronary Syndrome (ACS), High On-treatment Platelet Reactivity (HTPR), Microvascular Obstruction (MVO [evidence.nhs.uk]

Treatment Treatment of MVA includes full control of cardiovascular risk factors and all other conditions that might impair clinical outcomes (i.e. inflammatory status, oestrogen deficiency, high adrenergic activity). [ncbi.nlm.nih.gov]

Coronary microvascular dysfunction, microvascular angina, and treatment strategies. JACC Cardiovasc Imaging 8 : 210–220, 2015. Crossref PubMed ISI Google Scholar 23. [physiology.org]

Prognosis has been reported to be good in patients with MVA in the absence of conditions known to be associated with increased risk. [ncbi.nlm.nih.gov]

[…] and management of stable ischemic heart disease 28 May 2014 - Publisher: Canadian Cardiovascular Society The main focus of this guideline is on adult patients with suspected or known SIHD, covering 4 fundamental processes: establishing diagnosis and prognosis [evidence.nhs.uk]

While its recognition is of clinical importance, its prognosis is excellent. (Braunwald, Heart Disease, 4th ed, p1346; Jablonski Dictionary of Syndromes & Eponymic Diseases, 2d ed). [idref.fr]

Acetylcholine-provoked coronary spasm at site of significant organic stenosis predicts poor prognosis in patients with coronary vasospastic angina. J Am Coll Cardiol 66 : 1105–1115, 2015. Crossref PubMed ISI Google Scholar 15. [physiology.org]

[…] develop this condition, and there is some evidence that suggests that there are genetic mutations that predispose to the syndrome. [3] Women are more prone to this condition than men, as well as those who have a history of heart disease in the family. [4] Pathophysiology [en.wikipedia.org]

A pathophysiologically based approach should be preferred over a ‘first line’ and ‘second line’ recommendation. [ncbi.nlm.nih.gov]

Microvascular coronary dysfunction in women-pathophysiology, diagnosis, and management. Curr Prob Cardiol 36 : 291–318, 2011. Crossref PubMed ISI Google Scholar 20. Kubota T, Chiba K, Ishizaki T. [physiology.org]

CRT 04:32 CRT 2019: Rivaroxaban 2.5 mg BID combined with DAPT for the prevention of... Radcliffe Cardiology [rutherfordmedicine.com]

Node et al. ( 25 ) reported that EETs prevented leukocyte adhesion to the vascular wall by a mechanism involving inhibition of transcription factor, nuclear factor-κB, and IκB kinase. [physiology.org]