Presentation
Simple Education 720 Videos 125 Topics Topics: Aorta · Coronary arteries · PCSK9 Antagonists · Anti-Platelet Drugs Event: International Society of Cardiovacular Pharmacology Speakers: Juan Carlos Kaski Summary Management of Microvascular Angina - Presented [rutherfordmedicine.com]
This review briefly addresses the clinical presentation, mechanisms and management of patients with chronic primary stable MVA. [ncbi.nlm.nih.gov]
From the group of patients in the present study who complained of chest pain and did not present with epicardial stenosis, MVA was diagnosed in 23.4% of the patients, which was consistent with the rate reported by previous studies ( 22, 25 ). [physiology.org]
There is at present no known cure however a change in lifestyle is important. Patients should start following healthier diets which are low in saturated fats, and should participate in regular physical activities. [en.wikipedia.org]
Entire Body System
-
Abdominal Obesity
The risk factors include abdominal obesity, meaning excessive fat tissue in and around the abdomen, atherogenic dyslipidemia which is a blood fat disorder, and elevated blood pressure. [2] Other risk factors are insulin resistance or intolerance to glucose [en.wikipedia.org]
-
Atrial Septal Defect
Left main coronary trunk compression by dilated main pulmonary artery in atrial septal defect. Report of three cases. J Thorac Cardiovasc Surg 104 : 449–452, 1992. PubMed ISI Google Scholar 11. [physiology.org]
Cardiovascular
-
Heart Disease
More: Ongoing Trials Canadian Cardiovascular Society Guidelines for the diagnosis and management of stable ischemic heart disease 28 May 2014 - Publisher: Canadian Cardiovascular Society The main focus of this guideline is on adult patients with suspected [evidence.nhs.uk]
ATP-CFR, adenosine triphosphate-induced coronary flow reserve; VSA, vasospastic angina; IHD, ischemic heart disease. Intracoronary ACh-provocation test. [physiology.org]
-
Heart Failure
Microvascular angina is an chronic long term condition which increases the risk of heart attack and other cardiac events such as heart failure and frequent hospital admissions.The treatment consists of drugs, mainly to relieve chest pain, but a very important [en.wikipedia.org]
We excluded patients with possible heart failure (left ventricular ejection fraction 12-mm left ventricular wall thickness in echocardiography), severe hypertension (HT; 160/110 mmHg), valvular heart disease, and malignant diseases. [physiology.org]
-
Vascular Disease
This study was supported in part by Grants-in-Aid for the Japan Heart Foundation, Tokyo, and the Japan Vascular Disease Research Foundation, Kyoto, Japan. No conflicts of interest, financial or otherwise, are declared by the author(s). [physiology.org]
Psychiatrical
-
Withdrawn
Vasoactive drugs, including calcium-antagonists, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and nitrates were withdrawn at least 5 days before patients entered this study; sublingual nitroglycerin was withdrawn within 24 [physiology.org]
Workup
Serum
-
Dyslipidemia
Dyslipidemia (DLP) was defined as low-density lipoprotein 140 mg/dl, high-density lipoprotein 150 mg/dl. [physiology.org]
The risk factors include abdominal obesity, meaning excessive fat tissue in and around the abdomen, atherogenic dyslipidemia which is a blood fat disorder, and elevated blood pressure. [2] Other risk factors are insulin resistance or intolerance to glucose [en.wikipedia.org]
Treatment
[…] part of the treatment is regularly visiting the doctor and repeating the tests to make sure the condition was taken care of in full. [en.wikipedia.org]
Read Summary - More: Systematic Reviews The Effect of IV Cangrelor and Oral Ticagrelor Study Source: UK Clinical Trials Gateway - UKCTG - 05 April 2016 Coronary Syndrome (ACS), High On-treatment Platelet Reactivity (HTPR), Microvascular Obstruction (MVO [evidence.nhs.uk]
Treatment Treatment of MVA includes full control of cardiovascular risk factors and all other conditions that might impair clinical outcomes (i.e. inflammatory status, oestrogen deficiency, high adrenergic activity). [ncbi.nlm.nih.gov]
Coronary microvascular dysfunction, microvascular angina, and treatment strategies. JACC Cardiovasc Imaging 8 : 210–220, 2015. Crossref PubMed ISI Google Scholar 23. [physiology.org]
Prognosis
Prognosis has been reported to be good in patients with MVA in the absence of conditions known to be associated with increased risk. [ncbi.nlm.nih.gov]
[…] and management of stable ischemic heart disease 28 May 2014 - Publisher: Canadian Cardiovascular Society The main focus of this guideline is on adult patients with suspected or known SIHD, covering 4 fundamental processes: establishing diagnosis and prognosis [evidence.nhs.uk]
Acetylcholine-provoked coronary spasm at site of significant organic stenosis predicts poor prognosis in patients with coronary vasospastic angina. J Am Coll Cardiol 66 : 1105–1115, 2015. Crossref PubMed ISI Google Scholar 15. [physiology.org]
Pathophysiology
[…] develop this condition, and there is some evidence that suggests that there are genetic mutations that predispose to the syndrome. [3] Women are more prone to this condition than men, as well as those who have a history of heart disease in the family. [4] Pathophysiology [en.wikipedia.org]
A pathophysiologically based approach should be preferred over a ‘first line’ and ‘second line’ recommendation. [ncbi.nlm.nih.gov]
Microvascular coronary dysfunction in women-pathophysiology, diagnosis, and management. Curr Prob Cardiol 36 : 291–318, 2011. Crossref PubMed ISI Google Scholar 20. Kubota T, Chiba K, Ishizaki T. [physiology.org]
Prevention
CRT 04:32 CRT 2019: Rivaroxaban 2.5 mg BID combined with DAPT for the prevention of... Radcliffe Cardiology [rutherfordmedicine.com]
Node et al. ( 25 ) reported that EETs prevented leukocyte adhesion to the vascular wall by a mechanism involving inhibition of transcription factor, nuclear factor-κB, and IκB kinase. [physiology.org]