Presentation
We present 5 cases of progressive hemiparetic corticospinal tract degeneration, identified by the clinical presentation and the exclusion of other etiologies using serological, imaging, and electrodiagnostic studies. © 2015 S. [karger.com]
In this article, we describe a case of a middle-aged woman (initial presentation and three years follow-up) who presented with progressive ascending hemiparesis with clinically isolated upper motor neuron signs and normal sensory examination. [x-mol.com]
We describe a case (initial presentation and one year follow-up) of progressive ascending hemiplegia with clinical isolated upper neuron signs and normal sensory examination, discussing its nosological status, electromyographic findings, differential [mdpi.com]
However, only minor clinical and EMG involvement of LMN, which are not severe enough to meet ALS diagnostic criteria, may be present. [ncbi.nlm.nih.gov]
Physical examination (4 and 8 years after presentation) The gait was unsteady and broad-based. [link.springer.com]
Respiratoric
- Aspiration
She ultimately developed progressive pseudobulbar palsy and died 3 years later from aspiration pneumonia. Case 4 A 45-year-old left-handed man presented with a 4-year history of dragging his right leg when walking. [karger.com]
Musculoskeletal
- Flexion Contracture
He then developed a severe right flexion contracture of the right hand with progressive right lower limb spasticity and a spastic gait. [karger.com]
There were early flexion contractures of the fingers in the right hand with marked hypertonia in the right upper and lower limbs. [link.springer.com]
- Leg Weakness
On neurological examination, the right upper limb weakness was noted to be worse distally in the arm, with both proximal and distal pyramidal weakness in the right leg. There was normal strength in the left arm and leg. [karger.com]
Patient 3 This right-handed retired male noticed progressive weakness in the right leg at age 60, 2 months after a low velocity road traffic accident. [link.springer.com]
- Arm Weakness
On neurological examination, the right upper limb weakness was noted to be worse distally in the arm, with both proximal and distal pyramidal weakness in the right leg. There was normal strength in the left arm and leg. [karger.com]
Urogenital
- Incontinence
He did not have any sensory complaints, bulbar symptoms, or bowel or bladder incontinence. His neurological examination showed only mild facial asymmetry and asymmetric spasticity as well as hyperreflexia affecting the right upper limb. [karger.com]
Neurologic
- Hyperreflexia
His neurological examination showed only mild facial asymmetry and asymmetric spasticity as well as hyperreflexia affecting the right upper limb. [karger.com]
Neurological examination showed left hemiparesis3 with hyperreflexia, spastic hypertonia4 and Babinski sign. Although, on the right side, just the patellar jerk was increased, it was less intensely then the left one, with no signs of fasciculations. [ncbi.nlm.nih.gov]
Mild pyramidal weakness (Medical Research Council (MRC) grade 4) and hyperreflexia were noted in the right upper and lower limb. [link.springer.com]
- Limb Weakness
weakness in a patient with a 10-year history of slowly progressive left-sided hemiparesis. [tandfonline.com]
On neurological examination, the right upper limb weakness was noted to be worse distally in the arm, with both proximal and distal pyramidal weakness in the right leg. There was normal strength in the left arm and leg. [karger.com]
- Dysarthria
On examination, she had a spastic dysarthria with facial asymmetry. She had mild right-sided pyramidal distribution weakness. [karger.com]
- Steppage Gait
His gait was notable for a very mild reduction of the left arm swing and a left steppage gait. The laboratory investigations are detailed in table 1. Case 3 A 88-year-old woman presented with a 2-year history of a gait disorder. [karger.com]
- Foot Drop
Case 5 A 72-year-old woman presented with a 3-year history of left foot drop, with subsequent evolution to involve weakness of the entire left lower limb. [karger.com]
Treatment
[…] syndrome" New changes, new therapies, new information and news Full title Mills syndrome Synonyms Amyotrophic lateral sclerosis, hemiplegic type Name in a foreign language - CONTENT INFORMATION Textual description Etiology Forecast Differential diagnosis Treatment [retkebolesti.com]
Traditionally, Carpal Tunnel treatment has been limited to decompression surgeries, physiotherapy, and prescription medicines. [newtownchiroandpt.com]
Plectin-targeted lisosomes enhance the therapeutic efficacy of a PARP inhibitor in the treatment of ovarian cancer. Theronostics 8(10):2782-98. [med.virginia.edu]
Her only past medical history of note was of curative (local) treatment for ductal breast carcinoma (11 years after onset of neurological symptoms). There was no family history of neurological disease. [link.springer.com]
Prognosis
[…] case (initial presentation and one year follow-up) of progressive ascending hemiplegia with clinical isolated upper neuron signs and normal sensory examination, discussing its nosological status, electromyographic findings, differential diagnosis and prognosis [mdpi.com]
UMN-ALS is different from classical ALS in the progression rate and time of survival, which enables a better long-term prognosis. [ncbi.nlm.nih.gov]
If our criteria are satisfied, based on our experience and review of the literature, a number of statements can be made with regard to prognosis. First, no patient with the condition has yet died directly from Mills’ syndrome. [link.springer.com]
Etiology
[…] to get new information about "Mills syndrome" New changes, new therapies, new information and news Full title Mills syndrome Synonyms Amyotrophic lateral sclerosis, hemiplegic type Name in a foreign language - CONTENT INFORMATION Textual description Etiology [retkebolesti.com]
We present 5 cases of progressive hemiparetic corticospinal tract degeneration, identified by the clinical presentation and the exclusion of other etiologies using serological, imaging, and electrodiagnostic studies. © 2015 S. [karger.com]
A syndrome is a collective of symptoms and signs that could have many etiologies. [ncbi.nlm.nih.gov]
Epidemiology
[…] and news Full title Mills syndrome Synonyms Amyotrophic lateral sclerosis, hemiplegic type Name in a foreign language - CONTENT INFORMATION Textual description Etiology Forecast Differential diagnosis Treatment Diagnostic methods Antenatal diagnosis Epidemiology [retkebolesti.com]
Targetable immune regulatory molecule expression in high-grade serous ovarian carcinomas in African-American women: A study of PD-L1 and IDO in 112 Cases from the African American Cancer Epidemiology Study (AACES). [med.virginia.edu]
Pathophysiology
Predominantly unilateral primary degeneration of corticospinal pathways is the supposed underlying pathophysiological mechanism. [tandfonline.com]
Prevention
Killien, B Mills, AV Lele, MS Vavilala JAMA network open 2 (8), e199448-e199448, 201952019Prior arrest, substance use, mental disorder, and intent-specific firearm injury BM Mills, PS Nurius, RL Matsueda, FP Rivara, A Rowhani-Rahbar American journal of preventive [scholar.google.com]
Financial health & the pathology trainee: Fiscal prevention, diagnosis, and targeted therapy for young physicians. Arch Path Lab Med 2018;142(1):12-15. S Zadeh, L Duska, AM Mills. Androgen receptor expression in endometrial carcinoma. [med.virginia.edu]